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특집 - 2007 당뇨협회가 만난 사람들 - 당뇨병, 예방 교육에 힘써야... -
박성우,Park, Seong-U 사단법인 한국당뇨협회 2007 당뇨 Vol.217 No.-
"당뇨병은 예방이 가장 중요합니다. 국가적인 차원에서 노력해 전단계인 사람들을 찾아내야하고 교육, 관리해 주는 것이 가장 중요합니다." 박성우 교수는 당뇨병에 있어 가장 중요한 것은 무엇보다 예방과 교육이라고 강조한다. 전당뇨인들이 당뇨병에 걸리기 전 미리미리 예방하고, 이미 당뇨가 온 환자라면 올바르게 관리해 나갈 수 있도록 의료진과 협회, 국가정책 당국이 함께 손잡아야 한다는 것이 박 교수의 생각이다.
박성우,안송지,양희범,권진경,강병철 한국원예학회 2009 Horticulture, Environment, and Biotechnology Vol.50 No.1
High resolution melting (HRM) analysis is an inexpensive, simple, and rapid detection technology for single nucleotide polymorphism (SNP). In this study, we tested and applied HRM analysis for SNP marker discovery in pepper. To obtain accurate and reproducible HRM results, the PCR conditions were tested first. Factors affecting PCR reactions also affected HRM results. Best HRM results could be obtained with the PCR condition of 1.5 mM of MgCl2, 60 mM of KCl, and 2.5 ng・μl-1 of template DNA. With the optimized PCR condition, the usefulness of HRM analysis for SNP detection was evaluated for 60 COSII markers with known SNP information. SNPs were successfully detected by HRM analysis with an average success rate of 65% (39 of 60). SNPs were most successfully (about 90%) detected for amplicons smaller than 250 bp in size. Among the SNPs, single base pair changes were the most successfully detected (79.2%). This study is the first report about on HRM application in pepper which demonstrates that HRM will be a very useful tool for SNP discovery and application in pepper.
박성우,신용철,고성규,Park, Seong-Woo,Shin, Yong-Cheol,Ko, Seong-Gyu 대한예방한의학회 2008 대한예방한의학회지 Vol.12 No.1
Background : Diabetes is a chronic disease characterized by deficiency of insulin. It has been reported that Fructus aurantii and mulberry leaves have the effect of anti-diabetes. Methods : To investigate the improvement of mixed extracts of Fructus aurantii and mulberry leaves on lipid metabolism, we performed double-blinded, randomized and placebo-controlled multi-center clinical trial. Results : Mixed extracts of Fructus aurantii and mulberry leaves significantly reduced total cholesterol. Conclusion : These results suggest that mixed extracts of Fructus aurantii and mulberry leaves improve lipid metabolism.