유자와 탱자 과피 추출물의 항산화 및 면역 활성 효과

박준희(Joon Hee Park),강병원(Byoung Won Kang),김지은(Ji Eun Kim),서민정(Min Jeong Seo),이영춘(Young Choon Lee),이재헌(Jai Heon Lee),주우홍(Woo Hong Joo),최영현(Yung Hyun Choi),임학섭(Hak Seob Lim),정영기(Yong Kee Jeong),이복규(Bok Ky 한국생명과학회 2008 생명과학회지 Vol.18 No.3

본 연구는 탱자(Poncirus trifoliata) 과피의 80% 에탄올 추출물(PTP)에 대한 항산화 활성과 면역 활성을 유자(Citrus junos) 과피 추출물(CJP)과 비교하였다. 총 phenol 함량과 총 flavonoids 함량은 PTP가 각각 60.75±1.15 ㎎/100 g과 33.75±0.15 ㎎/100 g이었으며, 이는 CJP에 비해 다소 낮았다. PTP의 항산화 활성은 농도 의존적으로 증가하였으며 CJP의 항산화 활성과 비슷하게 나타났다. 면역반응 중 대식세포가 생성하는 NO 생성량을 측정한 결과 CJP와 PTP를 단독으로 처리한 경우와 LPS와 혼합하여 처리한 경우 모두 1㎎/ml까지는 대조구와 비교하여 농도 의존적으로 증가하였으나 고농도에서는 감소하는 경향을 나타내었다. 비장세포를 이용한 면역세포 증식능에서 CJP와 PTP를 첨가한 경우, 1 ㎎/ml까지는 대조구와 비교하여 농도 의존적으로 증가하였으나 고농도에서는 감소하였다. In this study, we compared with 80% ethanol extracts from peel of Poncirus trifoliata (PTP) and peel of Citrus junos (CJP) against antioxidant and immune activities. Total phenolics and flavonoids contents in PTP extracts were 60.75±1.15 and 33.75±0.15 ㎎/100 g, respectively, and those were lower than CJP extracts. Antioxidant activities of PTP were increased with the more concentration, and were similar to CJP. Antioxidant activities of PTP were increased with increasing of concentration, and were similar to those of CJP. The NO production in macrophage cell lines were increased in a dose-dependent manner, until 5 ㎎/ml of CJP and 1 ㎎/ml of PTP compared with control cells, but decreased at higher concentrations. The proliferation of mouse spleen cells were increased in a dose-dependent manner, until 1 ㎎/ml of CJP and PTP compared with control cells but decreased at higher concentrations. The NO production in macrophage cell lines treated with PTP and CJP were increased in a dose-dependent manner, compared with untreated control cells until the concentrations of 1~5 ㎎/ml (CJP) and 1 ㎎/ml (PTP) but decreased at higher concentrations than that. The proliferation of mouse spleen cells treated with PTP and CJP were increased in a dose-dependent manner, compared with untreated control cells until the concentration of 1 mg/ml but decreased at higher concentrations than that.

서울市內 乳兒 運動能力의 發達

尹南植(Nam Sik Yoon),朴俊熙(Choon Hee Park),林美子(Mi Ja Yim) 이화여자대학교 교육과학연구소 1975 교육과학연구 Vol.4 No.-

체외순환적용시 비박동성 관류법과 박동성 관류법간의 혈류역학과 신장기능 비교 : 관상동맥우회술 환자를 대상으로 Centered on the patients undergoing coronary artery bypass grafting with cardiopulmonary bypass

박준희,이현화,홍용우,심연희,곽영란,이춘수 대한마취과학회 2000 Korean Journal of Anesthesiology Vol.39 No.6

서울市內 幼兒 運動能力의 發達

尹南植,朴俊熙,林美子 이화여자대학교 사범대학 교육과학연구소 1975 인간발달연구 Vol.4 No.-

The purpose of the present study is to collect basic data which might be made use of in the practical teaching and planning of physical education programs. The study also sets out to discover the patterns of motor ability development in childhood. Out of the childhood population in Seoul City, samples of 449 children (ages between 3 to 12) of both sexes were selected at random. The samples were studied in terms of their motor ability development and the results are summarized as follows: Ability to produce physical movement? 1. It was uncovered that children of both sexes experience the straight development of the lower limbs muscle power and that the age for spurt phenomenon is 5.6 to 6.0 for males and 4.0 to 4.6 for females Male is superior to female in power of the lower limbs muscles. 2. It was discovered that children of both sexes experience the straight-wise development of power in the upper limbs muscles and the difference in power between male and female tends to widen gradually according to chronological transition. 3. It was found that between 3.6 to 4.0 years in males a spurt phenomenon is observed But afterwords a straight development is shown. Male is superior to female in speed. 4. Strength or power of children develops through increasing muscle quantity according to chronolgical transition in parallel with stature or body weight without special training. Ability to continue physical movement 5. It was discovered that it is generally straight-wise development in muscular endurance except spurt phenomenon for males of 4.0 and 4.6 years old and there has been found a wavy type in the case of females of 4.0, 4.6 and 5.6 years old are superior to males in muscular endurance. 6. Children can not continually move stably, because children can not produce strength steadily for a long time, This is due to the slow development of children constive power ability to coordinate physical movement 7. There has been found a wavy type according to chronological transition in flexibility development in the case of males and has been found ceasing phenomenon in the case of females. Male is superior to female in flexibility. 8. It was uncovered that it is straight-wise development in stunt ability in both sexes, and that it decreases individual differences according to chronological transtion. Male is superior to female in stunt ability. 9. It was found out that it is straight-wise development in balance according to chronological transition in both sexes. Female is superior to male at 4.0, 4.6 and 5.6 years old in balance, and it decreases individual differences according to chronological transition, (or "individual differences decrease")? 10. In the motor ability of child-hood develops first coordination, second strength, third power, and fourth muscular endurance. Therefore physical activities in child hood should be satisfied through various free play games.

서울市內 幼兒 運動能力의 發達

尹南植,朴俊熙,林美子 이화여자대학교 한국문화연구원 1975 韓國文化硏究院 論叢 Vol.26 No.-

The purpose of the present study is to collect basic data which might be made use of in the practical teaching and planning of physical education programs. The study also sets out to discover the patterns of motor ability development in childhood. Out of the childhood population in Seoul City, samples of 449 children (ages between 3 to 12) of both sexes were selected at random. The samples were studied in terms of their motor ability development and the results are summarized as follows: Ability to produce physical movement? 1. It was uncovered that children of both sexes experience the straight development of for males and 4.0 to 4.6 for females Male is superior to female in power of the lower limbs muscles. 2. It was discovered that children of both sexes experience the straight-wise development of power in the upper limbs muscles and the difference in power between male and female tends to widen gradually according to chronological transition. 3. It was found that between 3.6 to 4.0 years in males a spurt phenomenon is observed. But afterwards a straight development os sown. Male is superior to female in speed. 4. Strength or power of children develops through increasing muscle quantity according to chronological transition in parallel with stature or body weight without special training. Ability to continue physical movement. 5. It was discovered that it is generally straight-wise development in muscular endurance except spurt phenomenon for males of 4.0 and 4.6 years old and there has been found a wavy type in the case of females of 4.0, 4.6 and 5.6 years old are superior to males in muscular endurance. 6. Children can not continually move stably, because children can not produce strength steadily for a long time. This is due to the slow development of children costive power ability to coordinate physical movement. 7. There has been found a wavy type according to chronological transition in flexibility deveent in the case of males and has been found ceasing phenomenon in the case of females. Male is superior to female in flexibility. 8. It was uncovered that it is straight-wise development in stunt ability in both sexes, and that it decreases individual differences according to chronological transition. Male is superior to female in stunt ability. 9. It was found out that it is straight-wise development in balance according to chronological transition in both sexes. Female is superior to male at 4.0, 4.6 and 5.6 years old in balance, and it decreases individual differences according to chronological transition. (or "individual differences decrease")? 10. In the motor ability of child-hood develops first coordination, second strength, third power, and fourth muscular endurance. Therefore physical activities in child-hood should be satisfied through various free play games.