대학을 중심으로 한 기초과학육성의 당위성

주충로,Ju, Chung-Ro 한국과학기술단체총연합회 1988 과학과 기술 Vol.21 No.4

인삼 Saponin 의 생화학적 연구 ( Ⅳ ) 말 및 닭의 간 Alcohol Dehydrogenase 에 미치는 영향

주충로,윤병희,이상직,한정호 ( Chung No Joo,Byung Hee Yoon,Sang Jik Lee,Jung Ho Han ) 생화학분자생물학회 1974 BMB Reports Vol.7 No.3

The effect of ginseng saponins on equine and chicken hepatic alcohol dehydrogenases was investigated spectrophotometrically and the following results were obtained. 1) The Km values of equine and chicken hepatic ADH were found to be 8 × 10^(-4)M and 5.1 × 10^(-4)M respectively. 2) When the concentration of ginseng saponins of ADH reaction mixture in the presence of known amounts of ADH and ethanol, the activity of ADH increased gradually as the concentration of the saponins increased. It was found, however, that the activity of the hepatic ADH decreased when the concentration of the saponins was over 0.53 × 10^(-3) % (horse) and 0.27 × 10^(-3) % (chicken) respectively. 3) The velocity-concentration curves of the ADH reactions in vitro in the presence of the saponins ranging from 1.33 × 10^(-5) % were found to be sigmoid. 4) It was realized that the effect of the saponins on ADH activity was dependent not only upon its concentration but also upon the concentration of substrate and that the optimal concentrations of saponins and ethanol for the maximum activity of horse ADH were 1.33 × 10^(-5) % and 2∼4 mM respectively.

基礎科學育成을 爲한 提言 : 歷史的考察을 中心으로

朱忠魯 연세대학교 교육연구소 1988 연세 교육연구 Vol.1 No.2

오늘날 우리들이 살고있는 문명은 물질적인 측면에서 과학없이는 존재할 수 없을 뿐 아니라 문명의 지적 및 도덕적 측면에서도 과학은 깊은 관계를 가져왔고 과학은 끊임없이 점점 더 크게 우리 사회에 작용하고 있다 금세기 후반에서의 과학기술의 급속한 진보는 세계 각국에 강력한 충격을 주었고,특히 과학기술이 국민총생산 신장에 크게 기여한다는 점에서 과학기술의 진흥은 중요한 국가적 과제로 되어있다.

인삼 사포닌이 지용성 비타민(A와 E)의 흡수에 미치는 영향

朱忠魯,金斗植,全英運 연세대학교 자연과학연구소 1978 學術論文集 Vol.1 No.-

본 연구에서는 人蔘 Saonin 이 不水溶性 Vitamin인 Vitamin A와 Vitamin E의 吸收에 미치는 영향을 쥐(albino rat, 100~120g ♂)를 使用하여 觀察하고 다음과 같은 結果를 얻었다. 1) Vit. A 를 人蔘 Saponin 과 함께 Stomach tubing法으로 投與한후 쥐의 血淸을 조사한 結果 試驗群의 Vit.A의 含量은 對照群보다 2倍나 된다. 그러나 3時間後부터는 過量의 Vitamin含量이 減少되기 시작하였다. 試驗群의 肝의 Vitamin A含量도 對照群의 1.5倍였으며 3時間後에는 正常 Vitamin量으로 回復되었다. 2) Vit.E의 경우도 Vitamin E를 投與하고 40分後에 血淸과 肝에서의 Vit. E含量을 調査한 結果 試驗群이 對照群에 比하여 1.4~1.5倍였다. 3) 위와같은 實驗結果는 人蔘 Saponin이 Vit. A와 Vit. E의 吸收를 促進한다는 것을 意味하는 것이다. 4) 한편 試驗群의 腎藏에서의 Vitamin含量이 對照群에 比하여 훨씬 높은 것은 人蔘 Saponin이 不水溶性 Vitamin의 吸收뿐 아니라, 移動 및 排泄에도 크게 영향을 미칠것으로 예상된다. It was attempted in this experiment to observe the effect of ginseng saponin on the absorption of water insoluble Vitamins such as Vitamin A and Vitamin E using albino rat (150-200g,♂) and the following result were obtained. 1) When the Vitamin A and ginseng saponin were fed by stomach tubing, Vit. A concentration of blood serum of test group was found as much as twice that of control, but the Vitamin A content started to decrease 3 hours after. The Vitamin A content of the liver of test animal was also found about 1.5 times that of control and its value returned to normal value three hours later. 2) The Vitamin E contents of the blood and lover of test animals were found as much as 1.4-1.5 times that of control 40 minutes after feeding. 3)The above results suggested tha saponin stimulated the absortion of water insolubl Vitamin A and E 4) On the other hand, the contents of the above Vitamins in the kidney of test animals were significantly higher suggesting that the ginseng saponin also affects the transport of the above water insoluble Vitamins.

現代 産業技術의 特質과 科學敎育

朱忠魯 연세대학교 교육대학원 1977 연세교육과학 Vol.11 No.-

We are all living in the age of science and it is now well recognized that politics, economic prosperity and civilization of our society anti even philosophical problems cannot be dealt with without considering science and technology today. It is also true that science and technology became an indispensale strategic tool for the rapid development of society, particularly for the developing country like Korea. Therefore, science education and its development became one of the serious facing issues of this country. Science of today is growing rapidly and it is one of the characteristics of modern science that it is finely dividing into a number of specialized fields but on the other hand they are going to group into several catagories. Furthermore, industrial technology is so intimately interlinked to science that no industrial development can be made without the background of science and scientific research. Actually science today acts a leading role in industry and few people would venture to assert that the prosperity and industrial development of any society can expect otherwise the rational science education and scientific research being carried out steadily. Science today occupies the heart of modern industry and it is rapidly spreading over industry through scientific production and administration. This rejects the social significance of modern Science. Historical events tell us that well organized and planned policy of science and technology did catalytic role unexceptionally for the prosperity of society in the past. Furthermore, it should he reminded that new technologies were brought by scientific findings and it is extremly dangerous to consider science and technology separately. It cannot he overestimated to emphasize the signifance of fundamental science for industrial development and prosperity of society. We know that science and technology have been developed before industrial prosperities were made, and well organized science education and policies were prepared before the development of science and technology. It is clear therefore that improvement of science education, both teaching contents and methods, must be urgently required to meet the development of industry and prosperity of thin society. There is no doubt that the purpose of science education today is not any more to teach systematic scientific knowledge as before. Rather I think it is necessary to teach fundumental concepts governing today's science and technology and scientific methods so that they may handle their own problems in the future and enjoy their lives rationally in the highly developed scientific society. Accordingly the content of the text of science education must be carefully selected to meet their lives in the future. It is realized that modern science governing today's industry would be consisted of nuclear physics, electronics, polymer chemistry and molecular biology. Baaed on the above fields of science, what it is called universe development has been initiated. From the above considerations, it is suggested that we all, educators, scientists as well as industrial people and government officials have to pay their extreme attention to set up rational programs for science education and scientific research in the very near future, and hoped the programs being carried out properly and steadily for the prosperity of this country.

科學 Curriculum 改善의 動向

朱忠魯 연세대학교 교육대학원 1979 연세교육과학 Vol.14 No.-

Curriculum reform movement of Science education was initiated in 1976 and the Curriculum study has been made towards formulating "Concept and process centered Science Curriculum", what is called "investigative curriculum. " Recently developed integrated and/or individualized Science curricula are also based on the idea of the above concept and process centered curriculum but extended the area that the fundamental concept fevers and/or considered not only concepts and process of the Science but also the feeling side of the students. It is quite true that the purpose of science educntion cannot be accomplished successfully even with a perfect curriculum when the ability and feeling of the students are ignored. Therefore the individualized science curriculum will be ideal one toward which the currumt study is approching. For the successful achievement of the above developed curriculum, the role of teachers are of great significance. As pointed out through the experimental teaching of PSSC course at school, it is necessary to retrain school teachers to meet the new science curriculum. Particularly in a developing country like ours, we are suffering from the lack of qualified teachers. Of course, there are a number of well trained teachers, but most school teachers in this country have received old fashioned education at home and they have not enough experience of scientific experiments to meet the new curriculum requirements. It is urgent, therefore, to establish a sound and practical retraining courses for school science teachers to carry out the new science curriculum successfully. I suggest that it is possible to retrain the school teachers at academic institution such as graduate school of education. It is also realized that the number of experiments required in the current curriculum is far beyond the practically limited available teading time at middle school. This signified that a new experimental program must be organized under the full cooperation of scientist and school teachers. Finally it must be pointed out that the supply of laboratory equipments, reagents, materials and assistants should be satisfied and the teacher's over-load should be avoided. It is quite natural that the satisfactory science education cannot be expected without a sufficient educational investigation as the good products are not produced without properly organized instruments and machines. It is clear that improvement of science education, both teaching contents and methods, must be urgently required to meet the developing and properity of this society. There is no doubt that the purpose of science education today is not any more to teach systemtic scientific knowledge as before but to teach fundamental concepts grovering today's science and scientific methods so that they may handle their own problems in the future and enjoy their lives rationally in the highly developed scientific society. Accordingly the contents of the text of science education must be carefully reselected to meet the above requirment. From the above consideration, the government officials, industrial people and school authorities have to pay their atention to organized rational programs for science education.

生命科學의 發展과 倫理問題

朱忠魯 연세대학교 교육대학원 1973 교육논집 Vol.6 No.1

모든 학문의 목적이 인류복지와 문화의 창조에 있다면 과학도 그 예외가 될 수 없으며 생명과학의 발전은 생명현상의 정확한 이해에 있는 것이지 그 지식의 악용으로 인류의 타락이나 멸망을 초래해서는 안됨은 의심할 여지가 없다. 또한 과학의 발전은 그 영역내에서의 한계점을 지니고 있으며 어디까지나 외적인 현상 이해에 끝이게 될 것이다. 오늘날 생명과학의 발전으로 파생되는 여러 사회윤리의 변천은 문제가 되고 있으며 많은 염려를 자아내고 있으나 이것이 반드시 과학의 발전에만 그 이유가 있는 것으로는 생각치 않는다. 기계가 개발되고 성능이 좋은 기계일수록 그것을 다루는 기술자의 훈련이 필요한 것과 같이 과학이 발전할수록 그 과학을 이해하고 이용하는 우리의 내면적 요소 즉 정신적 밑바탕이 건전하게 뒤따라야 하기 때문이다. 과학자는 과학자로서의 건실한 진리탐구에 최선을 다해야 할 것이고 이에 수반되는 교육, 문화, 철학, 사회, 종교등 각 영역에서의 큰 발전이 절실히 요망되는 것이다.