忠南地方의 胃腸 및 呼吸器系統의 癌에 對한 臨床 및 病理學的 硏究

徐輔祥,韓龍燮,崔鎔直,李泰淑 忠南大學校 1974 論文集 Vol.13 No.1

Clinical and pathological observations on cancers of the gastrointestinal and respiratory tracts, of which clinical and histopathologic materials were collected in the Chungnam National University Hospital and in the Chungnam area, were performed and the major results were summarized as follows: 1. Clinically, the peak age incidence was 6th decade, and more frequent in male. More frequently involved organs was the stomachand the next, lungs. In patients of stomach carcinomas chief complaints were epigastric pain and discomfort, loss of appetite, vomiting and epigastric fullness. In lung cancers those are prostration, extrapulmonary signs, symptoms and edema of the face. 2. Pathologically the type of stomach carcinomas are mostly of ulcero-infiltrative type, of which infiltration into the stomach wall is almost penetrated the serosal layer. In colonic carcinomas the peak age incidence was the 6th decade, but the 5th decade and under 30 years of age were involved in significantly large numbers of patients. Females are more frequent than males in colon carcinomas. In carcinomatous infiltration into the colonic wall, most cases are perforated up to serosal layer, and hence it is likely of suggestive that the most operative cases were late stage of this disease process.

《주제발표5》수학 및 과학교사 현직 연수의 문제점과 그 개선방안

서보상 경북대학교 과학교육연구소 1987 科學敎育硏究誌 Vol.37 No.1

Autoradiography에 依한 마우스 腎臟組織의 細胞環에 關한 硏究

徐輔祥 慶北大學校 醫科大學 1970 慶北醫大雜誌 Vol.11 No.2

Autoradiography에 依한 마우스 腎臟組織의 細胞環에 關한 硏究

徐輔祥 慶北大學校 醫科大學 1970 慶北醫大誌 Vol.11 No.2

Recent studies have shown that thymidine, a DNA precursor, is selectively taken up by cells synthesizing new DNA in prepararation for cell division. The use of tritiated thymidine for labeling cells in DNA synthesis combined with autoradiography has provided a powerful tool for the study of cell proliferation. Further, since DNA is metabolically stable, cells once labeled can be followed in their migrations and even through changes of cell type. After injection into animals tritiated thymidine is distributed by the blood stream, and cells which are undergoing DNA synthesis at the time of administration remain identifiable as labeled cells. In addition, inasmuch as the labeled thymidine of these cells will halve with each subsequent mitotic divison, it becomes possible to determine the average duration of the intermitotic interval of these cells within a given period of time. In a cell population which constantly is being renewed, individual cells divide periodically. This process of mitosis and interphase (periods between cell divisions) is termed the cell cycle. Toward the end of interphase, DNA is synthesized, this being called the DNA duplication or the S stage. After the S stage, the cell enters a relatively quiescent period prior to mitosis called the postduplication or G2 stage and then passes through prophase, metaphase, anaphase and telophase. At the termination of G1 stage of interphase, which lasts until DNA duplication occurs prior to the succeeding mitosis. In the present study, age changes in these four features of ^3H-thymidine labeling were examined in the mouse kidney. Mice of five ages, 14th day of gestation to 20 day postnatal, were given a single injection of ^3H-thymidine and the changes with age in the proportion of cells synthesizing DNA synthesisat the time of injection examined in several histological regions of the kidney such as renal corpuscle, convoluted tubule, and collecting tubule because, embryologlically, the independent origin of the nephrons and the collecting tubules in the embryo has been mentioned.

胃公腸吻合部 潰瘍穿孔 : Report of 2 Cases

徐輔祥,崔鎔直,韓龍燮 中央醫學社 1975 中央醫學 Vol.28 No.3

In spite of the progress in gastric surgery, the anastomotic or marginal ulcer remains the not too uncommon and dramatic failure of surgery for duodenal ulcers. The acute complication, or free perforation of anastomotic ulcers creating an emergency condition still occurs with sufficient frequency to merit consideration of the therapeutic problems involved. Two cases of free perforation of anastomotic ulcers treated surgically were presented together with a Emitted review of the literature on the subject. The first case had undergone emergency partial gastrectomy for bleeding duodenal ulcer 1 year previously at a private clinic. Laparatomy revealed a large amount of inflammatory fluid in the peritoneal cavity and a free perforation of anastomotic ulcer in the efferent loop of jejunum just below the gastrojejunostomy stoma. Another Billroth Il type gastrectomy and total vagotomy was carried out. The other case had undergone emergency partial gastrectomy for a perforated duodenal ulcer 3 months prior to admission. Laparatomy revealed a free perforation of anastomotic ulcer in the efferent loop of jejunum 3.5cm. Below the stoma. Another Billroth II type gastrectomy and total vagotomy was carried out.

先天性 巨大 薦尾骨 畸形腫 : 1例報告 A Case Report

韓相彬,徐輔祥,姜大榮,李泰淑 충남대학교 의과대학 지역사회의학연구소 1975 충남의대잡지 Vol.2 No.1

A sacrococcygeal teratoma, meassuring 21.0 × 13.0 × 13.0 cm and weighing 925 gm was resected from a new-born infant. Grossly the tumor is largely cystic and filled with serous fluid, and the solid mass was composed of many tissue components, i.e., skin, adipose tissue, nervous tissues with choroid plexus, intestinal mucosal epithelium containing goblet cells, and bronchial mucosa etc.

胃에서 發生한 Adenoacanthoma : 1例報告 및 文獻考察 A Case Report and Review of Literatures

成志鏞,徐輔祥,姜大榮,李泰淑 충남대학교 의과대학 지역사회의학연구소 1975 충남의대잡지 Vol.2 No.1

Adenoacanthoma or squamous-cell carcinoma originating in the gastric mucosa is a fairly rare malignancy while most of the carcinomas in the stomach are adenocarcinoma with varying degree of differentiation. A 44-year-old Korean male was admitted to Chung Nam National University Hospital because of abdominal pain, indigestion, constipation, abdominal fullness and palpable tumor mass in the upper abdomen for 18 months. Subtotally gastrectomized specimen showed a deep ulcer, measuring 3.5 × 3.0 × 2.0 cm along the lesser curvature of the pylorus, and the ulcer edge is elevated with neoplastic infiltration. Microscopically many irregular cancer pearls are scattered in the sheets or cords of tumor cells which are consisted mainly of anaplastic, but sometimes individually keratinizing large hyperchromatic squamoid cells. A few nodes draining stomach are also invaded by the new growths.

巨大尿管을 同伴한 二重尿管

成志鏞,徐輔祥,李泰淑 中央醫學社 1975 中央醫學 Vol.28 No.3

Duplication of the ureters occurs frequently, but a congenital double ureter with megaloureter is rather rare and has difficulty in diagnosis. This 3 year old female was admitted due to long lasting fever and abdominal distension for 16 month's duration. She also had paraplegia for 14 months, She was performed exploratory laparotomy due to markedly laterally displaced and distorted left renal pelvis and ureter, and was found to have hydronephrosis and megaloureter. She was performed adhesiolysis of distal periureteral fibrotic tissue on first operation resulting in successful decompression of hydronephrosis. But her symptoms recurred on 9th postoperative day. She was performed 2nd operation on 21st postoperative day and was performed left nephrouretectomy with good result. She was found to have incidental paraplegia due to poliomyelitis and active minimal pulmonary tuberculosis.

入院其間中 患者의 鼻腔내에서 分離한 葡萄狀球菌의 性狀에 關한 硏究

景龍澤,徐輔祥 中央醫學社 1975 中央醫學 Vol.28 No.3

An analysis was performed on characteristics of staphylococci isolated from 62 patients on the first, 4th and 7th hospital day, of staphylococci isolated from nasal cavities of 73 hospital employees, and of staphylococci isolated from the air of 16 places in Choong Nam University Hospital from May to Aug., 1974. The results were as follows: 1) The pollution rate by staphylococci in the air in the hospital was 35.6%. Coagulase test was positive in 14.7% of total bacterial colonies, and in 41.3% of isolated staphylococci. 2) The isolation rate of staphylococci from the nasal cavities of hospital employees was 83.5% and coagulase test was positive in 62.2%. 3) Isolation rates of staphylococci from the nasal cavities of patients were 70.3 on the first hospital day, 77.4% on the 4th day and 85.4% on the 7th day. 4) There was no specific differnces of antibiotic resistance between staphy-Iococci isolated from the air and from the nasal cavities of hospital employees, but there was the tendency of the increasing rate of appearing antibiotic-resistant strains according to the time lapse of hospitalization in the nasal cavities of patients. 5) The drugs which had been used with wide popularity in the province such as Streptomycin, Terramycin and ChioramphenicoI, had a higher resistance rate from the beginning of hospitalization. 6) Leucomycin was the most sensitive drug to isolated staphylococci in this study.

제27차 학술대회 : 98. 경부생검 ( neck biopsy ) 114예에 대한 분석보고

이용태,서보상 대한외과학회 1975 대한외과학회 학술대회자료집 Vol.- No.-