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쥐의 간 미토콘드리아 Aldehyde Dehydrogenase 의 분포와 특성에 관한 연구
최주영,주충노 ( Joo Young Choi,Chung No Joo ) 생화학분자생물학회 1992 BMB Reports Vol.25 No.5
Separation of inner membrane, outer membrane and matrix were accomplished by treating rat liver mitochondria preparation with digitonin followed by differential centrifugation. Mitochondrial ALDH isozymes were founded to be located in outer membrane as well as matrix fraction. Soluble low K_m ALDH in matrix had a very low K_m ($lt;10^(-6)M) for acetaldehyde, but the K_m of soluble high K_m ALDH in the matrix was 9.8 × 10^(-4) M, outer membrane bound ALDH showed a relatively high K_m, 1.4 × 10^(-2)M. The outer membrane bound ALDH was purified and characterized. Optimal pH was 9.5 and pI was 6.1. Subunit molecular weight was determined by SDS-PAGE and found to be 55,000. These results suggest that the soluble low K_m ALDH might be primarily response for the oxidation of acetaldehyde in rat liver, but the outer membrane bound ALDH will serve as barrier when the concentration of acetaldehyde in cytosol is high.
최주영 대진대학교 건설연구소 1998 건설공학논문집 Vol.1 No.-
This paper is to study the relation of urban design with ESSD(environmentally sound sustainable development). The priciples of sustainable development as defined by the agenda 21 of the world conforence on environment in Rio(Brazil) in 1992 provide some basic rules for the evaluation of our present practice and the necessary changes. Healthy and ecologically-sound city is real organisms that interact inside and the environment outside. Therefore to make ecologically-sound city, factors of urban design is ecologically-sound. This study presents that factors of urban design highly relate factors of ESSD.
최주영 대진대학교 2000 大眞論叢 Vol.8 No.-
This paper is to study regional development plan for Northern part of Kyonggi Province by ecological sustainable concept. The topic of regional development and the study of ESSD in the CCA/DMZ adjacent region is of growing interest to all, including from the international community. Therefore, to project regional development plan of ESSD this study presents general planning guide of regional development plan for Northern part of Kyonggi Province
신뢰성 있는 매쉬업 웹 애플리케이션 개발을 위한 보안 연구
최주영,김명주 서울여자대학교 2010 정보기술논문지 Vol.8 No.-
Mash-up is a new emerging web application that uses and combines data, presentation or functionalily from two or more sources to create new web services. In this paper, we suggest a strategic approach to support the development of trustworthy code-centric mash-up web applications which imports and integrates JavaScript codes. To show the benefit of mash-up, our system utilizes two open source API's - Heritirix and HTML Unit as a special purpose web crawler for JavaScript web pages and a non-GUI web browser respectively. For the accurate and concrete targeting web pages to analyze their trustworthiness, we have classified the JavaScript codes by HTML tags. The ultimate result of this research will be a trustworthiness reputation system for world-wide web applications, which will be helpful for mash-up developers to prevent and detect the malicious JavaScript code.
최주영,손방용 대진대학교 1996 大眞論叢 Vol.4 No.-
This study aims to is investigated the factor property of conventional market. The objects of this analysis are 143 conventional markets supplied during 35years from 1960 to 1995 in Seoul City that is one of typical large cities in Korea. Indices which were consisted of 13 physical fastors were established to analyze the conventional market. To understand the interrelation between indicies, 13 indices were grouped into 5 significent fadtors by Factor Analysis.
최주영,정성애,심기남,조원영,금보라,변정식,허규찬,장병익,장동경,정훈영,공경애,the Korean ESD Study Group 대한의학회 2015 Journal of Korean medical science Vol.30 No.4
The objective of this study was to conduct a meta-analysis to determine risk factors thatmay facilitate patient selection for radical resections or additional resections after apolypectomy. Eligible articles were identified by searches of PUBMED, Cochrane Libraryand Korean Medical Database using the terms (early colorectal carcinoma [ECC], lymphnode metastasis [LNM], colectomy, endoscopic resection). Thirteen cohort studies of 7,066ECC patients who only underwent radical surgery have been analysed. There was asignificant risk of LNM when they had submucosal invasion (≥ SM2 or ≥ 1,000 μm) (oddsRatio [OR], 3.00; 95% confidence interval [CI], 1.36-6.62, P = 0.007). Moreover, it hasbeen found that vascular invasion (OR, 2.70; 95% CI, 1.95-3.74; P < 0.001), lymphaticinvasion (OR, 6.91; 95% CI, 5.40-8.85; P < 0.001), poorly differentiated carcinomas (OR,8.27; 95% CI, 4.67-14.66; P < 0.001) and tumor budding (OR, 4.59; 95% CI, 3.44-6.13;P < 0.001) were significantly associated with LNM. Furthermore, another analysis wascarried out on eight cohort studies of 310 patients who underwent additional surgeriesafter an endoscopic resection. The major factors identified in these studies includelymphovascular invasion on polypectomy specimens (OR, 5.47; 95% CI, 2.46-12.17;P < 0.001) and poorly or moderately differentiated carcinomas (OR, 4.07; 95% CI, 1.08-15.33; P = 0.04). For ECC patients with ≥ SM2 or ≥ 1,000 μm submucosal invasion,vascular invasion, lymphatic invasion, poorly differentiated carcinomas or tumor budding,it is deemed that a more extensive resection accompanied by a lymph node dissection isnecessary. Even if the lesion is completely removed by an endoscopic resection, anadditional surgical resection should be considered in patients with poorly or moderatelydifferentiated carcinomas or lymphovascular invasion.
해계 유침 및 전침의 전․후 처치가 실험적으로 항진된 흰쥐의 장운동에 미치는 영향
최주영,이현 대한침구의학회 2010 대한침구의학회지 Vol.27 No.3
Objectives : The purpose of this study was to compare the effect of needle retention(NR) and electro-acopuncture of low(EA(L)) and high(EA(H)) frequencies at Haegye(ST41) on intestinal hypermotility induced with carbachol in rats Methods : We made over-activated state of intestinal motility with carbachol in rats and caried out needle retention acupuncture, low frequency electro-acopuncture and high frequency electro-acopuncture at Haegye(ST41) or sham point in rat devided into pre-treatment group and post-treatment group. And we resulted as followings from measuring charcoal travel rate with observation of intestinal motility. Results :1. None of acupuncture, low frequency electro-acopuncture and high frequency electro-acopuncture at ST41 had significant influences on intestinal motility of rat in normal state. 2. Pre-treated with acupuncture, low frequency electro-acopuncture and high frequency electro-acopunc- ture and post-treated with acupuncture and low frequency electro-acopuncture at ST41 didn’t significantly influences intestinal motility in rat which over-activated with carbachol. 3. Post-treated with high frequency electro-acopuncture at ST41 suppressed intestinal motility in rat which over-activated with carbachol. Conclusions : These results suggest that treatment high frequency electro-acopuncture at ST41 may be effective on gastric disorders such as intestinal hypermotility and its effect had more cure than prevention.