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      • 비점착성 사면의 그물식 뿌리말뚝의 보강효과

        박병수,유남재,최종상 江原大學校 産業技術硏究所 1998 産業技術硏究 Vol.18 No.-

        This paper is an experimental study of investigating the reinforcing effect and the behavior of cohesionless slope installed with reticulated root pils. Reduced scale model tests with plane strain conditions were performed to study the behavior of the strip footing located on the surface of cohesionless slopes reinforced with root piles. Model tests were carried out with Jumujin Standard Sand of 45% relativ density prepared by raining method to have an uniform slope foundation during tests. Slope of model foundaton was 1:1.5 and a rigid model slop. Parametric model tests were performed with changing location of model footing, arrangements of root piles and angles of pile installation. On the other hands, the technique with camera shooting was used to monitor sliding surface formed with discontinuty of dyed sand prepared during formation o foudation. From test resutls , parameters affecting the behavior of model footing were analyzed qualitatively to evaluate their effects on the characteristic of load - settlement, ultimate bearing capaity of model footing and failure mechanism based on the formation of fasilure surface.

      • 인체의 내분비 조직에서의 Renin 함유세포의 분포에 관한 면역 세포화학적 연구

        최종상,김한겸 고려대학교 의과대학 1989 고려대 의대 잡지 Vol.26 No.2

        The avidin-biotin- complex method with a monoclonal antibody to human renin was used to identify renin in human endocrine tissues. Renin immunoreactivity was found in some large cells of the anterior pituitary glands, the zona glomerulosa and the zona reticularis the adrenal glands, the Leydig cells of the testis, the follicular epithelial cells of the thyroid glands, and epithelial cells of the prostatic glands. The presence of renin in extrarenal tissues raises an intriguing hypothesis that there exists a "tissue renin-angiotensin system "which can locally regulate tissue functions.

      • 性 Hormone이 白鼠胸腺 비반세포에 對한 Prostaglandin F_(2α)의 作用에 미치는 影響에 關한 實驗的 硏究

        崔宗相,李大一,白承龍 고려대학교 의과대학 1982 고려대 의대 잡지 Vol.19 No.3

        The effects of sex hormones and prostaglandins to the tissue mast cells are variable by the animal species and tissue examined. While there are reports that the thymus has a certain control mechanism of the tissue mast cells, studies concerning effects of sex hormones and prostaglandins on mast cell of the thmus are rare. The purpose of this study is to understand influences of sex hormones to the effect prostaglandin F_(2α) on thymic mast cell in animal model. Two hundred female adult albino rats, weighing 150 gm. in average, were subjected to bilateral oophorectomy to eliminate the effects of sex hormones from ovaries, and subsequently sex hormones and prostaglandin F_(2α) were subcutaneously injected. Five rats in each group were sacrificed daily on to 5 days after injections. Obtained tissue was processed by usual paraffin sectioning and stained with Radden's modified toluidine blue staining method. The total numbers of mast cells in 30 high power fields (×400) were counted and findings in each group were compared. The results obtained are as follows; 1. The numbers of mast cells in oophorectomized control group were in the range of from 71.5±7.9 to 92.5±2.1 throughout the experimental period, and there was no significant change with time interval. 2. In estrogen injected group, the numbers of mast cells showed maximum (150.6±40.6) at the first day after injection, and then continuously decreased to the level of 111.2±9.0 at the fifth day after injection. 3. In progesterone injected group, the number of mast cells were in the range of from 83.6±19.0 to 102.6±9.4 throughout the experimental period, similar with findings of the control group. 4. In testosterone injected group, the numbers of mast cells were in the range of from 62.3±14.6 to 76.0±13.0, which were lower than those of the control group. 5. In prostaglandin F_(2α) injected group, the numbers of mast cells were 94.8±14.2 at the first day after injection and showed increasing pattern throughout the experimental period, reaching the maximum numbers (111.8±17.8) at the fifth day after injection. 6. In the combined estrogen and prostaglandin F_(2α) group, the numbers of mast cells were 105.8±13.3 at the first day after injection and showed continuously increasing pattern, with the maximum numbers (131.6±17.8) at the fifth day after injection. This finding suggests that the estrogen has an effect of increasing the action of prostaglandin F_(2α) on the number of tissue mast cell in rat thymus about 20% in degree. 7. In the combined progesterone and prostaglandin F_(2α) group, the numbers of mast cells ranged from 82.8±14.7 to 93.4±7.2, and reflect that progesterone acts as an antagonistic mechanism to the effect of the prostaglandin F_(2α) on the thymic mast cell. 8. In the combined testosterone and prostaglandin F_(2α) group, and increased throughout the experimental period. It seems that testosterone acts synergistically with prostaglandin F_(2α) on the number of mast cell in rat thymus.

      • 睾丸腫瘍의 植物凝集素 表現에 관한 硏究

        崔宗相 고려대학교 의과대학 1984 고려대 의대 잡지 Vol.21 No.2

        Lectins are proteins and glycoproteins that bind specifically to mono- or oligosaccharides and are found primarily in plants. Since they are avalible commercially in pure from and their interactions can be inhibited and even reversed by simple sugars, lectins have been extensively used as proves of the structure and organization of cell membrance carbohydrate-containing components. Biotinylated 8 plant lectins-concanavalin A (Con A), peanut agglutinin (PNA), Ricinus commuis agglutinin Ⅰ(RCA Ⅰ) Ulex europaeus agglutinin Ⅰ(UEA Ⅰ), soybeen agglutinin SBA), dolichos biflorus agglutinin (DBA), wheat germ agglutinin (WGA) and pinellia ternate agglutinin (PTA)-were bound to paraffin sections of surgically resected human testicular tumors and visualized with avidin-horseradish peroxidase conjugated. The testicular tumors used were seminomas, embryonal carcinomas, teratocarcinomas and Leydig cell tumors with the contrast of normal testicular tissues. The results obtained are as followings: 1. In the normal testicular tissues Con-A, and RCA Ⅰ showed positive reactions with the spermatocytic cells and PNA showed positive reaction with the secondary spermatocytes and spermatozoa. 2. On the Letdig cells, in normal testicular tissue or Leydig cell tumors, Con-A, WGA, UEA Ⅰ and PTA revealed positive cytoplasmic reactions. 3. All the lectins used exhibited negative reactions on the neolastic cells of seminomas. However Con-A showed positive cytoplasmic reactions on the seminomatous components of teratocarcinomas. 4. Con-A and PTA showed positive cytoplasic reactions on the glandular components of embryonal carcinoma and WGA revealed linear positive reaction on the poorly differentiated cells of embryonal carcinomas. 5. Con-A and PTA showed granular positive reactions on the syncytiotrophoblasts in choriocarcinomatous components of teracarcinomas. 6. Wga and RCA I exhibited linear positive reactions on the neoplastic cells of endodermal sinus tumors. And Con-A showed positive reactions on the hyaline bodies of the tumors. With the results, there are changes in lectin receptors in the cell membranes either loss or acquire, between normal cells and neoplastic cells.

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        사도 바울의 삶과 사역에 나타난 개혁주의생명신학 -그 원리와 21세기 적용-

        최종상 ( Daniel Jong Sang Chae ) 개혁주의생명신학회 2012 생명과 말씀 Vol.6 No.-

        이 글은 유럽의 교회 감소상황을 전하면서 시작된다. 교회가 아무리 오랜 역사, 좋은 전통, 심오한 신학을 가지고 있다 할지라도 역동하는 생명력을 상실하면 교회는 무너질 수 있다는 것을 실증해 보이기 위해서다. 이 시대의 교회가 복음의 능력을 회복하여 세상을 구원하기 위해서는 무엇보다도 신학교들이 신학과 신앙과 실천을 균형있게 가르쳐야 한다. 하지만 아쉽게도 대부분의 신학교에서는 신학교육에만 치우쳐 있고, 그 신학도 주로 학문적으로 가르치고 있을 뿐, 학생들을 뜨거운 가슴의 신앙을 소유한 그리스도의 제자로 길러내지 못하고, 또 사역 현장에 나아가 배운 것을 실천하며 활용할 수 있는 준비된 사역자로 교육시키지 못하는 경우가 허다한다. 특히 신학을 “과학의 여왕”으로 여기며 가르쳐 왔던 유럽의 신학교들이 그러했다. 따라서 유럽의 교회는 오늘날 급속히 감소되었으며, 유럽은 심각한 선교지로 변했다. 개혁주의신학의 본산지인 유럽이 이렇게 된 것은 개혁주의신학에 생명이 결여되었기 때문이다. 사도 바울은 개혁주의생명신학의 원조(元祖)다. 그는 신학과 신앙과 실천의 균형을 유지하면서 생명력 넘치는 교회를 개척하고 목회한 대표적인 인물이었다. 바울은 오늘의 신학교와 교회가 본받아야할 모델이다. 이 글은 바울의 삶과 사역의 원리를 살펴보면서, 이 시대에 교회와 신학교가 배워 실천할 수 있는 영역을 제시한다. 바울은 복음 진리를 설명하고 수호하며 그의 신학을 표현하였다. 그의 복음의 핵심은 예수 그리스도와 그가 이루신 십자가와 부활이었다. 바울은 예수님과 복음을 향한 확신을 가지고 열정적으로 헌신한 그리스도의 제자였다. 더 나아가 그는 그리스도의 생명의 복음을 삶에 적용하며 실천하는 훌륭한 신앙인이었다. 이 글의 마지막 부분은 신학과 신앙과 실천의 균형을 유지했던 바울의 사역원리를 실천하고 있는 영국의 암노스교회개척학교의 사역자 훈련 사례를 소개하고 있다. 결론적으로 그리스도의 복음의 생명으로 교회를 살리자는 개혁주의생명신학은 한국뿐만 아니라 세계교회에 소개되고 수출되어야할 것이다. This article begins by surveying the decline of churches in Europe today. It makes the point that if the Church loses its life of dynamic vitality it is bound to fall even if it has a long history, good tradition and profound theology. If the church is determined to recover the power of the gospel and to save the world, it is vital for theological institutions to equip students with the balance in theology, discipleship and practice. Regrettably most theological institutions focus on teaching theology as merely an academic discipline. They pay little attention to equipping students as the disciples of Christ whose hearts are filled with passion and commitment. Their training does not offer students practical tools that they can use in their fields of ministry. It is the case particularly among the theological institutions in Europe, which regard theology as “the queen of science”. As a result the church in Europe has experienced a rapid decline, and Europe, which used to be the main force for mission, has now become a serious mission field. It is because reformed theology, which originated in Europe, lacks life in its theology. The Apostle Paul is the father of Reformed Life Theology. He was a model who planted life-giving churches and pastored them by keeping the balance with theology, discipleship and practice. The churches and theological institutions today need to take his example seriously. Paul expressed his theology by both explaining the truth of the gospel and defending it. The core of his gospel was Jesus Christ, his suffering on the cross and resurrection. He was a committed disciple of Christ who had firm and passionate conviction in the gospel. Furthermore, he was a Christian who put into practice the truth of the gospel in daily life. Amnos Church Planting School, UK, is introduced towards the end of this article, as a case institution which applies the Pauline principles in training church planters and pastors. The ethos of Reformed Life Theology, that is to revitalize the Church with the life of the gospel, needs to spread to the world.

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