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안희정(Hee-Jeong Ahn),최욱진(Uk-Jin Choi),심규식(Gyu-Sik Shim) 한국컴퓨터정보학회 2024 韓國컴퓨터情報學會論文誌 Vol.29 No.3
본 연구는 가정용 침대 위에서 발생한 심정지 환자에게 가슴압박을 수행할 경우 환자의 체중과 구조자의 체중에 따른 가슴압박 정확도의 차이를 확인하고자 하였다. 2023년 01월 07일부터 01월 19일까지 대한심폐소생협회의 KBLS 교육과정을 이수한 N대학교와 S대학교의 응급구조(학)과 학생 36명을 대상으로 대상자의 무릎 위치에서 매트리스가 눌리는 깊이, 마네킹의 무게에 의해 매트리스가 눌리는 깊이를 측정하였고, 2분간 연속된 가슴압박을 수행하는 동안 가슴압박 깊이, 속도, 압박 위치 불량, 가슴압박 깊이 50 mm 미만 횟수, 모든 변수를 고려한 정확도를 측정하였다. 연구결과 가정에서 소아 심정지를 발견한 경우 환자를 바닥으로 이동시켜 가슴압박을 진행하고, 성인 심정지를 발견한 최초목격자는 환자를 무리하게 침대 밑으로 내려 가슴압박을 진행하기보다는 침대 위에서 진행하는 것을 권장한다. The purpose of this study was to determine the accuracy of chest compression according to the patient body weight and the rescuers weight when performing chest compression on a cardiac arrest patient that occurred on a home bed. From January 07 to January 19, 2023, 36 paramedic students from N and S universities who completed the KBLS provider curriculum of the Korea Cardiopulmonary Resuscitation Association were measured at the subjects knee position, the depth of the mattress being pressed by the weight of the manikin, and the depth of the mattress being pressed by the weight of the manikin were measured during continuous chest compression for 2 minutes. As a result of the study, if a childs cardiac arrest is found at home, the patient is moved to the floor to proceed with chest compression, and the first witness to find an adult cardiac arrest is recommended to proceed on the bed rather than force the patient under the bed to proceed with chest compression.
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영어동화 듣기 활동을 통한 초등학교 영어 발음 교육 방안
안희정(Ahn, Hee-jeong),정현성(Chung, Hyunsong) 한국영어교과교육학회 2008 영어교과교육 Vol.7 No.2
The purpose of this study is to find out how listening activities of English fairy tales focusing on English pronunciation can improve not only the listening and speaking ability but pronunciation proficiency. It was implemented under the environment without any other private education by teaching one 6th grader in a primary school. The subject listened to one fairy tale a week for 23 weeks with the explanation of the pronunciation. The interview and 4 types of intonation (statement, Wh-question, Yes/No question, command) sentences were recorded. To figure out the improvement of pronunciation proficiency, the pronunciations were analyzed by using the acoustic analysis program (Praat) and by one native speaker. To evaluate the objective effect, the pre/post PELT jr Level 1 test scores and PELT jr speaking test scores were compared. The results show that listening instruction focusing on English pronunciation using fairy tales was proven to be very helpful. These results indicate that pronunciation-based practice enhances not only young learners’ pronunciation proficiency in the critical period but furthermore their listening and speaking ability.
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안희정(Hee-Jeong Ahn),김지영(Ji Young Kim),이충환(Choong-Hwan Lee),송임숙(Im Sook Song),유광현(Kwang-Hyeon Liu) 한국생명과학회 2008 생명과학회지 Vol.18 No.9
본 연구에서는 다양한 천연 추출물의 P-gp 저해능의 고속탐색을 통하여 새로운 화학감작제 후보물질을 발굴하고자 하였다. P-gp 활성에 대한 천연 추출물의 저해능은 P-gp이 과발현된 L-MDR1 세포주를 이용하여 대표적인 P-gp 기질 약물인 calcein AM의 세포 내 축적 정도를 측정함으로써 평가하였다. 강황 및 울금은 가장 강력한 P-gp 기능 저해를 나타내었고, 이외에도 Mentrasto, 취호초, 봉출, Rakta chandan, 강진향, 소목, 노회 등의 순으로 P-gp 기능 저해능을 보였다. 이들 추출물에서 P-gp 저해능을 보이는 성분을 확인하기 위하여 LC/MS/MS 분석을 수행한 결과, 기존에 P-gp 활성을 저해한다고 잘 알려진 curcumin 이외에, 다양한 플라보노이드 화합물이 질량 스펙트럼 DB 검색을 통하여 확인되었다. In vitro 연구 결과를 통하여 상기의 천연 추출물이 P-gp 활성을 저해하는 성분을 함유하고 있음을 확인하였다. 향후 이들 천연 추출물의 화학감작제 후보물질로의 사용 가능성에 대한 in vivo 연구가 필요할 것이다. 사업(R01-2007-000-10734-0) 및 2006년도 인제대학교 학술연구조성비의 지원에 의하여 이루어진 것임. P-glycoprotein (P-gp) is a very important drug transporter, which plays an important role in drug disposition and represents an additional mechanism for the development of multidrug resistance. Flavonoids, a major class of natural compounds widely present in foods and herbal products, have been shown to be P-gp inhibitors. The objective of the present study was to identify new chemosensitizer candidates through the screening of various herbal extracts. The inhibitory effects of herbal extracts on P-gp activity were assessed by measuring accumulation of calcein AM using P-gp overexpressed L-MDR1 cells. Curcuma longa showed the most potent inhibition on P-gp function. The inhibitory potential of P-gp was in the order: Curcuma longa > Curcuma aromatica > Ageratum conizoids > Zanthoxylum planispinum > Zedoariae rhizome > Rakta chandan > Dalbergia odorifera > Caesalpinia Sappan > Aloe ferox. To identify individual constituents with inhibitory activity, the herbal extracts were analyzed by LC/MS/MS. Several flavonoids such as curcumin, a well-known P-gp inhibitor, were identified through mass spectral library search. These in vitro data indicate that herbal extracts contain constituents that can potently inhibit the activities of P-gp and suggest that these herbal extracts should be examined for potential chemosensitizer in vivo.
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古事記における在の硏究 ─ 日本書紀の修飾構造の補足を含めて ─
안희정 ( Ahn Heejung ) 한국일본어교육학회 2017 日本語敎育 Vol.0 No.82
In this paper, I examined the usages of Zai (在) in Kojiki, and whether the form of “Zai + place + target” seen in Kojiki and Nihonshoki in which the phrase “Zai + place” qualifies “target” is a perfect Chinese sentence. The results are summarized as follows. Zai (在) in Kojiki was used a total of 59 times. It consists of 43 cases of “existence”, 3 cases “survival”, 1 case of “idiom”, 3 cases of “Japanese usage”, “misuse” 2 cases, and “modifying structure” 7 cases. This result was included in all the previous research results, but there are no usages of “to depend on”, “to stay in”, and “every”. Usage of “preposition” depends on whether “modifying structure” is accepted or not. 2) In the Nihonshoki, among the 21 cases of type A used as the modifying structure, 3 cases used together with Zhi (之) were authentic Chinese sentences, and among the 18 cases of type A used without Zhi 12 cases were used in the α group and eight cases in the β group. B type of “Ukijimari” has 4 cases; it is a special usage. C type is certainly misuse, but it can be found only in the β group, so it is an example supporting the validity of the theory of categories in the Nihonshoki. Three examples of type D are correct Chinese sentences. 3) From the point of view of Ancient Chinese, 6 cases of Kojiki and 18 cases of Nihonshoki should be seen as all “prepositions” except for one case used as a verb in Kojiki. Therefore, I think that the 24 cases are perfect Chinese sentences, and they do not turn away from the theory of categories in the Nihonshoki. It seems preferable to read “~ni (at ~)” as a preposition rather than “~ni aru(to be at ~)” as a modifying structure. In the case of a modifying structure, I do not think that reading Zai as “~ni aru” is incorrect “reading”. That is because I think that it is necessary to acknowledge the special nature of reading by the difference between the structure of Ancient Chinese and the structure of Old Japanese.
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제2형 당뇨병환자에서 식기를 활용한 식사계획법과 식품교환표를 활용한 식사계획법이 섭취량 조절에 미치는 효과
안희정 ( Hee Jung Ahn ),구보경 ( Boo Kyung Koo ),정지연 ( Ji Yeon Jung ),귄휘련 ( Hwi Ryun Kwon ),김현진 ( Hyun Jin Kim ),박강서 ( Kang Seo Park ),한경아 ( Kyung Ah Han ),민경완 ( Kyung Wan Min ) 대한당뇨병학회 2009 Diabetes and Metabolism Journal Vol.33 No.2
연구배경: 식품교환표를 활용한 식사계획은 제2형 당뇨병환자들에게 섭취량과 영양소 구성을 교정하는데 유용한 방법이다. 그러나 인지능력이 낮은 환자들은 이러한 교육내용을 이해하는데 어려움을 느낀다. 이에 본 연구는 한국인 제2형 당뇨병환자에서 정량화된 식기와 식품교환표를 활용하여 영양소 섭취량, 영양소 구성, 교육의 이해도에 미치는 효과를 조사해 보고자 하였다. 방법: 80명의 제2형 당뇨병환자는 정량화된 식기를 활용한 식사계획 군(BG)과 식품교환표를 활용한 식사계획 군(ExG)으로 분류하였다. BG는 식기 활용방법에 대해 간단히 교육하였다. 교육 시간은 BG에서 10분, ExG에서 40분 정도 소요하였다. 총 섭취량과 열량 영양소 섭취량은 3일 식사 기록지로, 교육의 이해도는 5점 척도로 조사하였다. 결과: 섭취 열량에 대한 순응도는 12주 교육 후 BG에서 103±10%, ExG에서 101±17%로 두 군 간 차이가 없었다. 두 군 모두에서 탄수화물과 단백질 섭취량이 유의하게 감소하였고, 그룹 간 총 섭취 열량에 대한 탄수화물, 단백질, 지방 섭취비의 차이는 없었다. 교육 후 이해도에서도 그룹간 차이는 없었다. 결론: 제2형 당뇨병환자에서 식기를 활용한 식사 계획법은 짧은 교육 시간에도 식품교환표를 활용한 식사계획법에 비해 섭취량과 열량 영양소 구성비 조절, 교육의 이해도에서 동등한 효과를 보였다. Background: The food exchange-based meal plan is effective in controlling dietary energy intake with a macronutrient balance. However, it is difficult to practice for relatively low-literacy patients. As an alternative, we developed a system employing a standardized-sized bowl and investigated its effectiveness on achieving proper energy intake and macronutrient composition and patient compliance, compared to the conventional food exchange system in Korean type 2 diabetes patients. Methods: Eighty subjects with type 2 diabetes were assigned to both the novel bowl-based meal plan group (BG) and the food exchange-based meal plan group (ExG). BG received limited simple instructions for the plan. Time spent for plan instruction was 10 min for BG and 40 min for ExG. Dietary energy and macronutrient intake were estimated with 3-day dietary records and patient comprehension of the plan was estimated with a 5-point Likert scale. Results: After 12 weeks, dietary energy compliance showed no difference between the groups (BG: 103±10%, ExG: 101±17%). Both groups showed significant reduction in carbohydrate and protein intake and there was no difference in the proportion of carbohydrate, protein and fat in energy intake between the groups despite the shorter instruction time for BG. Following the instruction period, there was no difference in the understanding score between the groups. Conclusion: This bowl-based plan was equally effective as the food exchange-based plan in controlling dietary energy intake and macronutrient composition, as well as patient comprehension and compliance. Our novel plan may allow for more cost-effective methods in terms of time needed for plan instruction. (Korean Diabetes J 33:155-163, 2009)
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