Wustite 의 전기전도도에 미치는 제3원소의 영향

백영현,김경대 고려대학교 공학기술연구소 1984 고려대학교 생산기술연구소 생기연논문집 Vol.20 No.1

Electrical conductivity measurements were respectively made on synthetic wustites which were doped with dilithium oxide. dialuminum trioxide and silicon dioxide in the temperature range of 20℃ to 1,000℃. The D.C. conductivity of the wustite was measured by means of the two-prove method. Their electrical conduction were found to be characterized by a typical semiconductor behavior. A plot of logarithm of conductivity versus reciprocal temperature was fairly linear, and the activation energy calculated there from was approximately 0.12eV below about 600℃. whereas above that temperature 0.042eV, Electrical conductivity of the wustite was increased by adding Li₂O or CaO and on the other hand decreased by adding Al₂O₃ or SiO₂ into wustite. This behavior could be explained in terms of lattice defect structure. It was found that the electrical conductivity of wustite was practically proportional to the concentration of electron hole i.e. Fe^(+3) in the lattice.

갑상선자극 호르몬 분비에 대한 Dopaminergic Control에 관한 연구

이정상,이문호,고창순,김응진,김명덕 대한핵의학회 1978 핵의학 분자영상 Vol.12 No.2

1978년 4월부터 1978년 8월사이에 서울대학교병원 내과에 내원하였던 원발성 갑상선기능저하증 환자 9명과 일반신체검사 및 갑상선기능검사상 전혀 이상이 발견되지 않은 의과대학생 6명과 수련의 1명 총 16명을 대상으로 Dopamine 수용체를 선택적으로 차단하는 Metoclopramide와 Dopamine 수용체를 선택적으로 자극하는 Bromergocryptine(CB-154)을 각각 혹은 함께 투여해서 다음과 같은 결과를 얻었다. 1) Metoclopramide(Moxolonⓡ) 10mg을 정맥으로 주사했을때 원발성 갑상선기능저하증 환자들에서는 투여후 20분에 말초혈액에서 갑상선자극호르몬이 통계학적으로 유의하게 증가되었으며, 60분에도 계속 증가되었다. 그 이후 180분까지 계속 증가된 장태를 유대했으며, 중증보다 경증에서 더욱 현저하게 증가되어 나타났다. 그러나 정상인에서는 이러한 증가가 나타나지 않았다. 2) Bromergocryptine(CB-154)을 2mg 경구투여했을때 원발성 갑상선기능저하증 환자들에서는 투여후 120분에 말초혈액에서 갑상선자극호르몬이 현저하게 감소되었고, 240분 및 360분까지 계속 감소되었으며, 중증보다 경증에서 더욱 현저하게 감소되어 나타났다. 그러나 정상인에서는 이러한 감소가 나타나지 않았다. 3) Bromergocryptine(CB-154) 2mg을 경구투여한 후 120분에 Metoclopramide(Moxolonⓡ) 10mg을 정맥 주사했을때 원발성 갑상선기능저하증 환자들에서는 Bromergocryptine을 투여한 후 120분에 말초혈액에서 갑상선자극호르몬이 감소했으며, Metoclopramid를 투여한 후에 약간 증가하는 추세였으나, Metoclopramide를 단독으로 투여했을 때와 같은 현저한 증가는 나타나지 않았으며, 정상인들에서는 Bromergocryptine 및 Metoclopramide를 투여했을때 뚜렷한 증가나 감소는 보이지 않았다. 4) 생리식염수 2ml를 정맥주사했을 때 원발성 갑상선기능저하증 환자들 및 정상인들에서 갑상선자극호르몬이 말초혈액에서 뚜렷한 증가 내지 감소는 보이지 않았다. 5) Metoclopramide와Bromergocryptine을 각각 혹은 함께 투여했을때 및 생리염수를 투여했을 때 혈중 Triiodothyronine 및 Thyroxine치는 각각의 기저치들에 비해 통계학적으로 유의한 증가나 감소를 보이지 않았다. 이상의 결과에서 갑상선자극호르몬의 분비가 Dopaminergic Control을 받는다는 사실을 알 수 있었다. 본 연구를 실시함에 있어 물심양면으로 협조해주신 동아제약에 사의를 표하는 바이다. To e1ucidate the depaminergic control of T.S.H. secretion, we analized the pattern of T.S.H secretion in seven normal controls and nine primary hypothyroid subjects, before and after single or combined administration of specific dopaminergic receptor blocker, metoclopramide, and specific depaminergic receptor stimulant, bromergocryptine (CB-154). The results obtained were as follows: 1) There was a significant rise in T.S.H. levels after intravenous injection of metocioramide(10mg) in hypothyroid subjects. But there was no significant rise in T.S.H. levels in normal controls. The T.S.H. response to metoclopramide varied considerably, being large in mild cases and small in severely hypothyroid subjects. 2) There was a significant fall in T.S.H. levels after oral administration of bromergocryptine(2mg) in hypothyroid subjects, but there was no significant fall in T.S.H. levels in normal controls. 3) There was no significant fluctuation in T.S.H. levels after combined administration of both metoclopramide and bromergocrytine. 4) There was no significant fluctuation in T.S.H. levels after intravenous injection of normal saline(2ml) in both hypothyroid and normal subjects. 5) There was no significant change in serum T3 and T4 after administration of metoclopramide and bromergocryptine respectively and serially. These data support the fact that there is a dopaminergic control in the secretioI1 of T.S.H. in the human.

Al 첨가에 의한 CV 흑연주철의 흑연조직 및 성질에 관한 연구

김수영,전대진,허보녕 대한금속재료학회(대한금속학회) 1984 대한금속·재료학회지 Vol.22 No.9

In this study, CV graphite cast iron was made from adding small amount of A1 after making an incomplete spheroidal graphite by adding small amount of Fesi-Mg alloy. As a result, it was found that CV ratio and graphite length were increased as increasing amount of Al addition and holding time, but graphite width was decreased, Also, it was found that brinell hardness value 170-190 HB and tensile strength value 38-40 ㎏/㎟ of the CV graphite cast iron were closer to those values of the spheroidal than those values of the flake graphite cast iron, but thermal diffusivity value 7.8×10^(-6)㎡/sec of the CV graphite cast iron was closer to that value of the flake than that value of the spheroidal graphite cast iron.

RIHSA와 131I-Hippuran으로 측정한 심박출량의 비교

김정일,고창순,이안기,길광수,박진영,김동섭 대한핵의학회 1970 핵의학 분자영상 Vol.4 No.2

저자들은 정상성인 남자 11예에서 방사성동위원소인 RIHSA와 (131)^I-Hippuran을 사용하여 체외계측법에 의한 심박출량을 측정하여 다음과 같은 결론을 얻었다. 1) RIHSA를 사용한 심박출량의 측정치는 6750±866ml/min, 심계수의 측정치는 3960±476ml/min./㎡이었다. 2) 131I-Hippuran을 사용한 심박출량의 측정치는 5940±764ml/min, 심계수의 측정치는 3490±396ml/min./㎡이었다. 3) (131)^I-Hippuran에 의한 심박출량의 측정치는 RIHSA를 사용한 심박출량의 측정치의 88%로 나타났으며 양자간의 차이는 통계학적의미를 가지고 있었다(P$lt;0.05). 4) (131)^I-Hippuran을 사용하여 심박출량측정이 가능함을 알 수 있었다. Repeated measurement of cardiac output in the same 11 normal individuals were done with (131)^I-Hippuran and RIHSA. Following results were obtained. 1) The cardiac output measured with RIHSA was 6750±866ml/min. 2) The cardiac output measured with (131)^I-Hippuran was 5940±764ml/min. 3) The relative value of cardiac output measured with (131)^I-Hippuran to that measured with RIHSA was 88 percent, and a statistical significance was found present in the difference.

T3-BSA,T4-BSA 접합체 제조 및 생성항체의 방사면역측정적 이용 연구

오옥두,김재록 대한핵의학회 1980 핵의학 분자영상 Vol.14 No.1

1) T₃-BSA 및 T₄-BSA는 Morpho CDI를 coupling agent로 사용하여 pH 5.5에서 12시간 정도 실온 하(10∼20℃)에 반응시키는 것이 효고적이며 특히 T₄의 경우는 DMF를 충분히 가해야 침전생성을 막을 수 있다. 2) 제조한 T₃-BSA 및 T₄-BSA의 접합 mole비율은 각각 8∼9:1 및 4∼5:1이었다. 이들을 사용하여 얻은 항혈청의 RIA용 적정 희석비율은 각각 1.5×104:1 및 2×103:1이었으며 교차반응성은 T₄항체가 T3항체에 비해 7∼8배 컸다. 따라서 T₄항체가가 낮게 얻어지는 이유는 T₄-BSA의 접합비율이 낮다는 사실 이외에 T₄-BSA접합체 제조, 정제, 면역등 일련의 과정에서 T₄-BSA의 T₃- BSA로의 분해에 기인한다고본다. 3) T₃나 T₄를 ester화 하지 않은채로 만든 접합체를 써서 얻은 항혈청으로도 RIA용 적정 항혈청 희석비율율에서의 교차반응영향은 무시됨으로 T₃, T₄ RIA가 가능하였다. T₃-BSA, T₄-BSA conjugates were prepared and identified spectrophotometrically. The lambda-max on the conjugates was just coincided with that of BSA, but the molar extinction coefficients of the conjugates were generally larger than that of BSA itsalf. The molar ratios of T₃:BSA and T₄:BSA in the prepared conjugates were found to be 9:1 and 5:1, respectively. The titers of the T₃ antisera were generally higher (max. 1.5×104:1) than those of T₄ (max.2×103:1), and the average cross reactivity of the T3 antibody with T₄ was lower (0.45%) than that of T4 antibody with T₃(3∼4%). The results of the study indicate that the predominant cause of the lower titers and the lower specificity of the T₄ antisera comparing with those of T₃ is mainly due to the unstability of the T₄-BSA and consequent degradation of the conjugate to T₃-BSA during preparation, purification, and even during immunization. The lower molar ratio of T₄ to BSA in the preparation stage is also considered to be a minor factor. By measuring T₃, T₄ les in the reference control serum, it has been confirmed that the prepared antisera can sufficiently be utilized, respectively, in the established radioimmunoassay systems.

티타늄 스폰지를 이용한 수소 흡장 특성

이성호,김광락,안도희,유재형,백승우,손종식,임성팔,정홍석 한국공업화학회 2001 응용화학 Vol.5 No.2

Hydrogen absorption experiments were carried out by the titanium(Ti) sponge for investigating the characteristics of hydrogen absorption. From experimental results, Ti sponges showed the high hydrogen absorption capacity inspite of low reaction temperature. The H/M which mean the capacity of hydrogen absorption was measured 2.0 for Ti sponge in the experimental condition of 25℃. The effects of the reaction temperature, activation conditions, and the presence of helium in the hydrogen were investigated.

지르코늄의 트리튬 저장을 위한 수소흡수 예비실험

이성호,김광락,안도희,이한수,정흥석,강희석,백승우 한국공업화학회 1999 응용화학 Vol.3 No.2

A hydrogen absorption apparatus was installed for the experiment of hydrogen absorption as a basic procedure for the tritium immobilization. The basic experiment on the hydrogen absorption was conducted by using the zircaloy scrap and the sponge. The surface of the zircaloy scrap was activated and the equilibrium time on hydrogen absorption was determined. Morphology change of the zircaloy scrap was observed according to the progress of activation. The value of H/M measured under the hydrogen condition of 46 atm showed about 2.04 at 600℃ in case of the zircaloy scrap and about 2.01 at 400℃ in case of the zirconium sponge, respectively. These values were maximum allowable hydrogen storage capacity in zirconium.

기체 크로마토그래피를 이용한 수소동위원소 혼합물의 분리 특성

이성호,김광락,안도희,이한수,유재형,정흥석,강희석,백승우 한국공업화학회 1999 응용화학 Vol.3 No.2

Gas chromatography has been used as one of the practical methods for separation and enrichment of hydrogen isotopes in filds of operation or handling a hydorgen isotope facility. Chromatographic separation experiments of a mixture of hydorgen isotopes including with hydorgen, hydrogen deutride and deuterium. The complete separation of hydrogen isotopes was observed with an alumina adsorbent partially deactivated by coating with 10% manganese chloride(MnCl₂).

수소동위원소 교환반응 촉매 지지체의 경도에 대한 용매의 효과

이성호,김광락,안도희,이한수,정흥석,강희석,백승우,최희주 한국공업화학회 2000 응용화학 Vol.4 No.1

Polymeric catalyst supports for hydrogen isotope exchange reaction were prepared by using the various good and poor solvents. Effect of solvent was investigated experimentally on the hardness of these polymeric supports. P55OE1 showed the highest hardness and low ratio of micro pore area to total pore area. P55TE2 showed high hardness and ratio of micro pore area to total pore area. Therefore P55TE2 was expected to be the best polymeric support with regard to the performance and the hardness of the catalyst.

소결 경질 탄화물에 화학 증착법으로 TiC 를 증착시킬때 그들의 성질에 관한 연구

이채우,이동복,천성순,김재곤 대한금속재료학회(대한금속학회) 1980 대한금속·재료학회지 Vol.18 No.5

화학 증차법을 이용하여 WC-Co합금의 substrate위에 TiC를 증착시킬때 coating층의 성장과 내마모성질을 조사하였다. 증착온도 및 시간, substrate의 Co함량이 증가할수록 coating층의 두께는 현저한 증가를 보였으며 증착온도가 증가함에 따라 우선방위는 <100>으로부터 random orientation을 나타내었다. TiC coating한 시편은 내마모저항을 현저히 증가시켰으며 이에 대한 원인도 논하였다. Growth of coating layer and wear properties of chemically vapor deposited (CVD) TiC onto WC-Co substrate were investigated. The deposition temperature, time and Co content of the substrate showed pronounced effects on the thickness of coating layer. The texture of TiC layer changed from <100> orientation at low deposition temperature (950℃) to random orientation at high deposition temperature (1050℃). The wear resistance of coated specimen was remarkably increased and enhanced wear resistance was also discussed.