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유치원에서의 꽃과 채소 가꾸기 활동이 유아의 정서지능 및 행복감에 미치는 영향
최민수(Choi Min-Soo),정영희(Jung Young-Hee),김정옥(Kim Jung-Ok) 한국영유아보육학회 2012 한국영유아보육학 Vol.0 No.72
본 연구는 G지역에 거주하는 유치원 원아 70명을 대상으로 꽃과 채소 가꾸기 활동이 유아의 정서지능 및 행복감에 어떠한 영향을 미치는 지를 알아보기 위한 목적으로 이루어졌다. 이를 위하여 두 가지 연구문제를 설정하였다. 첫째, 유치원에서의 꽃과 채소 가꾸기 활동이 유아의 정서지능에 미치는 영향은 어떠한가? 둘째, 유치원에서의 꽃과 채소 가꾸기 활동이 유아의 행복감에 미치는 영향은 어떠한가? 연구결과는 다음과 같다. 첫째, 유치원에서의 꽃과 채소 가꾸기 활동은 실험집단과 통제집단 비교에서 정서지능 하위영역인 자기인식, 감정조절, 타인인식, 대인관계 모든 영역에서 유의한 차이가 있는 것으로 분석되었다. 둘째, 유치원에서의 꽃과 채소 가꾸기 활동은 실험집단과 통제집단 비교에서 행복감 하위영역인 부모관계, 교사관계, 인지 및 성취, 몰입, 정서, 건강, 생활만족 영역에서 유의한 차이가 있었다. 이러한 결과를 볼 때 유아의 정서지능과 행복감 증진을 위해 꽃과 채소 가꾸기 활동의 체험들이 적절하고 의미 있는 교육활동으로 현장에 적용해 볼 수 있음을 시사해 주고 있다. The purpose of this study was to find out how flower and vegetable growing activity will have an influence on young children’s emotional intelligence and happiness. The subjects of study were 70 young children in the age group of 5 years at G kindergarten and H kindergarten. Among those 70 young children, each 35 young children were allocated to both experimental group and control group, respectively and then flow growing activity and vegetable growing activity were classified for separate allocation. The findings were as follows: First, flower and vegetable-growing activity had a positive influence on young children’s emotional intelligence. In particular, looking at the effect of emotional intelligence by sub-area, it was analyzed that there was a significant statistical difference in self-recognition, emotion adjustment, recognition of others, interpersonal relationship, and all areas-sub area of emotional intelligence between experimental group and control group. Second, flower and vegetable-growing activity had a positive influence on young children’s happiness. Looking at the effect of happiness by sub-area, it was appeared that there was a significant statistical difference in young children parent relationship, young children-teacher relationship, peer relationship, young children’s recognition and achievement, immersion, emotion, health, and satisfaction in life -subarea of happiness-between experimental group and control group, but no significant statistical difference in spirituality.
Young Hoon Choi,Ju Whi Kim,Jung Ok Shim,Hye Ran Yang,Ju Young Chang,Jin Soo Moon,Jae Sung Ko 대한소아소화기영양학회 2019 Pediatric gastroenterology, hepatology & nutrition Vol.22 No.3
Purpose: Vitamin D deficiency is a condition widespread throughout the world. Recent studies have suggested that vitamin D deficiency was associated with obesity and metabolic syndrome. The purpose of the study was to examine the relationship between vitamin D deficiency and nonalcoholic fatty liver disease (NAFLD) in adolescents. Methods: The data were obtained from the Korean National Health and Nutrition Examination Survey from 2008–2014. A total of 3,878 adolescents were included in the study. Vitamin D deficiency was defined as a 25-hydroxyvitamin D concentration <20 ng/mL and suspected NAFLD was defined as an alanine transaminase concentration >30 U/L. Results: Vitamin D deficiency was noted in 78.9% of the studied population. Age, body mass index, waist circumference, and blood pressure, glucose, cholesterol, and triglyceride levels were significantly higher in adolescents with suspected NAFLD than in adolescents without suspected NAFLD, while the mean vitamin D level was significantly lower in adolescents with suspected NAFLD. The multivariate-adjusted odds of suspected NAFLD were higher with increased age, male gender, obesity, and metabolic syndrome. Individuals with vitamin D deficiency were at higher risk of suspected NAFLD (odds ratio, 1.77; 95% confidence interval, 1.07–2.95) after adjusting for age, gender, obesity, and metabolic syndrome. Conclusion: Vitamin D deficiency was associated with suspected NAFLD, independent of obesity and metabolic syndrome, in adolescents.
Jung, Deok-Beom,Lee, Hyo-Jeong,Jeong, Soo-Jin,Lee, Hyo-Jung,Lee, Eun-Ok,Kim, Young Chul,Ahn, Kyoo Seok,Chen, Chang-Yan,Kim, Sung-Hoon Pharmaceutical Society of Japan 2011 BIOLOGICAL & PHARMACEUTICAL BULLETIN Vol.34 No.6
<P>Hypoxia inducible factor 1 alpha (HIF-1α) is frequently over-expressed in the numerous types of cancer and plays an important role in angiogenesis. In the present study, the inhibitory mechanism of rhapontigenin isolated from <I>Vitis coignetiae</I> was investigated on HIF-1α stability and angiogenesis in human prostate cancer PC-3 cells. Rhapontigenin significantly suppressed HIF-1α accumulation at protein level but not at mRNA level in PC-3 cells under hypoxia. Also, rhapontigenin suppressed hypoxia-induced HIF-1α activation in various cancer cells, such as colorectal adenocarcinoma (SW620), breast adenocarcinoma (MCF-7), fibrosarcoma (HT-1080) and prostate carcinoma (LNCaP). Interestingly, rhapontigenin had more potency in inhibition of hypoxia-induced HIF-1α expression than that of resveratrol, a known HIF-1α inhibitor. In addition, rhapontigenin promoted hypoxia-induced HIF-1α degradation and cycloheximide (CHX) blocked protein synthesis. A prolyl hydroxylase (PHD) inhibitor dimethyloxalylglycine (DMOG) is usually utilized to examine whether prolyl hydroxylation is involved in inhibition of HIF-1α accumulation. Here, DMOG recovered HIF-1α accumulation inhibited by rhapontigenin. Immunoprecipitation assay also revealed that rhapotigenin enhanced the binding of hydroxylated HIF-1α to von Hippel-Lindau (VHL) tumor suppressor protein. Furthermore, rhapontigenin reduced vascular endothelial growth factor (VEGF) secretion in hypoxic PC-3 cells as well as suppressed tube formation in human umbilical vein endothelial cells (HUVECs) treated by the conditioned media of hypoxic PC-3 cells. However, anti-angiogenic effect of rhapontigenin in hypoxic PC-3 cells was reversed by DMOG. Taken together, these findings suggest that rhapontigenin inhibits HIF-1α accumulation and angiogenesis in PC-3 prostate cancer cells.</P>
Nefopam Reduces Dysesthesia after Percutaneous Endoscopic Lumbar Discectomy
( Young Min Ok ),( Ji Hyun Cheon ),( Eun Ji Choi ),( Eun Jung Chang ),( Ho Myung Lee ),( Kyung Hoon Kim ) 대한통증학회 2016 The Korean Journal of Pain Vol.29 No.1
Background: Neuropathic pain, including paresthesia/dysesthesia in the lower extremities, always develops and remains for at least one month, to variable degrees, after percutaneous endoscopic lumbar discectomy (PELD). The recently discovered dual analgesic mechanisms of action, similar to those of antidepressants and anticonvulsants, enable nefopam (NFP) to treat neuropathic pain. This study was performed to determine whether NFP might reduce the neuropathic pain component of postoperative pain. Methods: Eighty patients, who underwent PELD due to herniated nucleus pulposus (HNP) at L4-L5, were randomly divided into two equal groups, one receiving NFP (with a mixture of morphine and ketorolac) and the other normal saline (NS) with the same mixture. The number of bolus infusions and the infused volume for 3 days were compared in both groups. The adverse reactions (ADRs) in both groups were recorded and compared. The neuropathic pain symptom inventory (NPSI) score was compared in both groups on postoperative days 1, 3, 7, 30, 60, and 90. Results: The mean attempted number of bolus infusions, and effective infused bolus volume for 3 days was lower in the NFP group for 3 days. The most commonly reported ADRs were nausea, dizziness, and somnolence, in order of frequency in the NFP group. The median NPSI score, and all 5 median sub-scores in the NFP group, were significantly lower than that of the NS group until postoperative day 30. Conclusions: NFP significantly reduced the neuropathic pain component, including paresthesia/dysesthesia until 1 month after PELD. The common ADRs were nausea, dizziness, somnolence, and ataxia. (Korean J Pain 2016; 29: 40-47)
First Record of Amphisiella milnei (Ciliophora, Stichotrichida) from Korea
Jung Min Choi,Jae-Ho Jung,Young-Ok Kim 한국동물분류학회 2018 Animal Systematics, Evolution and Diversity Vol.34 No.3
A marine ciliate Amphisiella milnei (Kahl, 1932) Horváth, 1950 was discovered from the tidal pool of Baekdo Island, South Korea. The existence of extra cirri between leftmost frontal cirrus and buccal cirrus discriminates this species from its congeners. Its morphological features are described as follows: body size in vivo 110-130×35-45 ㎛; elongate rectangular to elliptical in shape; two large and several small ring-shaped structures; yellowish cortical granules arranged irregularly on ventral side but longitudinally along dorsal kineties on dorsal side; 34-40 adoral membranelles, 3 frontal cirri, 1 buccal cirrus, 1 parabuccal cirrus, usually 2 extra cirri behind leftmost frontal cirrus, and 3 frontoventral cirri; amphisiellid median cirral row composed of 25-31 cirri with 27-36 left and 27-44 right marginal cirri; usually 5 transverse cirri and 2 pretransverse cirri with 7 dorsal kineties; two macronuclear nodules. In addition to, 18S rDNA sequence of A. milnei was analyzed to understand its phylogenetic relationship.