심실 중격 결손에 의한 감염성 심내막염 환자의 치과치료

양정현,현홍근,김영재,김정욱,장기택,이상훈,한세현,김종철 대한소아치과학회 2007 大韓小兒齒科學會誌 Vol.34 No.3

Craves병 환자에서 백혈구와 갑상선 조직의 HLA-DR β 유전자 부위의 비교

양인명,우정택,팽정령,서광식,김성운,김영설,김광원,최영길 경희대학교 유전공학연구소 1989 遺傳工學論文集 Vol.1 No.-

정상 갑상선세포에서는 HLA-DR 항원이 발현되지 않았으나, 그레이브스병 환자의 갑상선세포 표면에는 HLA-DR 항원이 발현됨이 보고되어, 이러한 현상은 이 질환의 자가면역 기전에 중요한 역할을 하고 있을 것으로 생각되고 있다. 한편 최근 DR이나 DQ 유전자의 상부 159kb 이내에는 이들의 발현을 조절하는 유전자가 존재함이 알려져 있고, 이 부위의 구조적인 변화로 인하여 DR DQ 유전자의 발현을 유도하는 여러 가지 핵내 인자들과 interferon-r 와 같은 외부인 자들이 보고되고 있다. 그러나 그레이브스병에서 이들 유전자 부위의 구조적인 변화에 관해서는 아직 보고가 없다. 이에 본 연구자 등은 이러한 가능성 여부를 규명하고자 2명의 전형적인 그레이브스병 환자의 수술 우 얻어낸 갑상선 조직에서 RNA를 분리한 우 DR β유전자를 소식자로 northem blotting을 하여 mRNA의 발현을 관찰하였으며, 말초혈액 백혈구와 갑상선 조직으로부터 분리된 DNA를 EcoRI BamHI. HindⅢ PvuⅡ TaqI, PstI등의 6가지 제한효소로 소화한 후 DR β유전자를 소식자로 하여 RFLP 양상을 비교한 결과, 환자 모두에서 mRNA의 발현이 관찰되었으나, 환자 모두에서 6가지 제한효소에 의한 RFLP 양상이 동일하였다. 이러한 결과는 Graves병 환자의 DR 유전자의 발현에 있어서 이 유전자 부위의 구조적인 변화가 관여할 가능성이 적음을 시사하는 사실이라고 사료되나 향후 더 많은 예와 더 많은 제한효소를 이용한 주시가 필요할 것이다. The requirement for major histocompatibility antigen class Ⅱ molecules in the recognition of antigen by helper T cells suggests that the expression of class Ⅱ antigen may be important in the initiation and prolongation of immunopathology. HLA class Ⅱ antigenes are expressed on the surface of thyrocytes of the patients with graves disease. The increased expression of class Ⅱgene can be induced by trans acting factor such as interferon However the possibility of rearrangement of their regulatory genes has not been explored so far. We studied the mRNA expression in the thyrocytes of 2 patients with Graves' disease and compared the restriction fragment length polymorphism (RFLP) between thyroid and peripheral leukocyte DNA. The prominent expression of mRNA was observed in the thyroid tissues of all the two patients. But we did not find any difference in RFLP pattern in both patients. These results suggest the possibility that the rearrangement of the regulatory gene located in the upstream of DR- β gene can be a role in expression of DR antigen is less likely.

좁쌀약주 釀造를 위한 균주의 선발

梁榮澤,高正三,康順善 濟州大學校亞熱帶農業硏究所 1991 亞熱帶農業硏究 Vol.8 No.-

As the manufacturing techniques of foxtail millet wine, a traditional wine in Cheju island, has been transfered by person to person, basic studies on this are not carried out yet. There are many difficulties to industrialize it successfully without improvement of wine quality. The purposes of this study were to screen saccharifying mold strain and brewing yeast for foxtail millet wine-making. Optimum reaction conditions of crude enzyme of Aspergillus oryzae on saccharifying soluble starch were 55℃, pH 5.6, Saccharifying activity of crude enzyme was maintained 31.0~35.4% at 20~25℃, fermentation temperature, compared to optimum enzyme reaction conditions. Saccharomyces cerevisiae IAM 4274 was selected as brewing yeast strain for foxtail millet wine-making.

인장하중을 받는 의사등방성 복합재 적층판의 피로손상

양광영,임경택,이동하,김택현,김인권 朝鮮大學校 機械技術硏究所 1999 機械技術硏究 Vol.2 No.1

The purpose of this work is to investigate fatigue damage of quasi-isotropic laminates under tensile loading in different directions. Low cycle fatigue tests of [O/-60/+60]s laminates and [+30/-30/90]s laminates were carried out. Materials systems used are AS4/Epoxy and AS4/PEEK. The fatigue damage of [+30/-30/90]s is very different from that of [O/-60/+60]s. The position of delamination generated at AS4/Epoxy and AS4/PEEK laminates were differentiated by the matrix difference that is, we suppose, the value of both G (critical energy release rate of mode-I) and G (critical energy release rate of mode-Ⅲ) difference. The experimental results are compared with the result obtained from the method of determining strain energy release rate components proposed by the authors.

농촌지역 주민의 농기계에 의한 손상에 관한 연구

양한설,이태용,이동배,조영채,심운택 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

To find out the incidence rate of farm machinery injuries for rural residents and to analyse characterisitics of injuries, we surveyed 10,075 rural residents from six Myons in Chungnam province from January 1, 1990 to Deccember 31, 1990 The results were as follows: 1. 94.4%(101 persons) of the injured were male; 5.6%(6 persons) female. 2. The annual incidence rate per 1,000 rural residents was 10.6 persons, and the annual incidence rate per 100 farm machines was 11.2 persons. 3. The number of the injured were more in mountainous district than in plain distict 4. Injuries were occured throughout the year but predominantly in April and October. Farm machines which caused accidents were power tillers, combine, and a farm tractor in that order of frequency. 5. The injured part of body were fingers and arms, foot and legs, the chest, and the waist in that order of frequency. 6. Most of the injured had been to medical institution for treatment. 7. The major cause of injuries was personal factor.

불악산(경기도)의 식물상에 관한 연구

안영희,안영철,최광율,박대식,정연택 중앙대학교 유전공학연구소 2001 遺傳工學硏究論集 Vol.13 No.1

Field surveys were carried out 3 times from 2000 5. 17 to 2000. 6. 4. Main results obtained from this study wet·e as follows : 1.The vascular Plants in Mt. Bull-ak were consisted of 221 taxa such as 71 families, 163 genera, 188 species, 30 varieties, 2 forma, 1 hybrid. 2.Family Compositae and Gramineae covers 8.6% and 7.2% of total number of naturalized plants, respectively. 3.Pteridophyte, Gymnosperm, Dicotyledon and Monocotyledon covers 2.5%, 2.7%, 75.9% and 18.1% of total number of naturalized plants, respectively. 4.The life cycle of the plants was annual 11.8%, biennial 11.3%, perennial 76.9%. As it compared with consistency ratio in the flora of Korea, the distribution of biennial appeared highly. 5.The highest peak of blooming month is May (49.3% among total number of naturalized plants). 6.In this area the Korean endemic plants are 5 taxa (2.3% among total number of naturalized plants). 7.Number of naturalized is 20 taxa (9.0% among total number of naturalized plant)

난치 천식으로 오인된 기관지 카르시노이드 종양 1례

어수택,김양기,이영목 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

A bronchial carcinoid tumor is identified in the patients with cough and normal chest PA or during routine examination of chest PA. Sometimes it is very difficult to diagnose the bronchial carcinoid tumor with normal chest PA, especially if the patient complains the typical symptoms of bronchial asthma. We experienced a 30 year-old female, who had been suffered from coughing and dyspnea in spite of asthma medications for 1 year, with bronchial carcinoid tumor. We describe here a case of bronchial carcinoid tumor mimicking refractory bronchial asthma.

해외에서 유입된 정상 면역 성인의 Varicella 폐렴 1예

조영관,박은경,김양기,이영목,어수택,김태형 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Varicella-zoster virus, an unusual pathogen of community acquired pneumonia in adult, may causes respiratory distress and death. Since the first description by Waring et al. in 1942, the disease has been recognized by roentgenography, pathologic study, and virus studies as a special syndrome of the varicella virus. Immunocompromized conditions such as leukemia, malignant lymphoma and corticosteroid therapy predispose patients to varicella pneumonia. It occurs rarely in immunocompetent patients. The clinical manifestations of varicella zoster pneumonia exhibit a wide spectrum of disease from asymptomatic to death. Acyclovir is the recommended treatment and corticosteroid can be used in severe varicella pneumonia. We report a case of varicella pneumonia developed in a immunocompetent patient.

인슐린 주사제의 고충실 액체색층기 분석

우정택,팽정렬,김성운,양인명,김진우,김영설,김광원,최영길 최신의학사 1993 最新醫學 Vol.36 No.8

아나필락시스를 동반한 Sweet 증후군 1례

이영목,어수택,김양기 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Sweet's syndrome is a neutrophilic dermatosis that has various clinical characteristics and is often associated with inflammatory, malignant or autoimmune diseases, so the viral or bacterial antigens and tumor antigens are suspected to play a role in the pathogenesis of Sweet's syndrome. We describe here a Korean male who had Sweet's syndrome accompanied by anaphylaxis.