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Song,Won-Seob,Chi,Hyung-Joon,Rim,Yo-Sup,Yoon,Jae-Ho 한국자원식물학회 2002 Plant Resources Vol.5 No.1
The material of Rhodiola sachatinensis collected from an alpine region of the west-northern China. For analysing the effect, 1 used Rhodiola sachatinensis s rhizome and cultivated callus. In EtOAc, BuOH, H₂0separation the plant showed strong antioxidative activity, but not in Hexane. The radical scavenging effect of EtOAc(RC50, 35(g), BuOH(RC50, 43(g), H₂0(RC50, 50(g) fraction and MeOH extract(RC50, 50(g) of the Rhodiola sachatinensis was comparable to that of synthetic antioxidant BHA(RC50, 14(g) and α-Tocopherol(RC50, 12(g). Total amino acid concentration of plant of In nature condition were 18,009ppm, and major components were arginine, glutamic acid, aspartic acid and valine. The ratio of essential/total amino acid on plant of In nature condition was 46.93%. Total amino acid concentration of callus of In vitro condition were 32,435ppm, and major components were valine, histidine, lysine and leucine. The ratio of essential/total amino acid on callus of In vitro condition was 56.07%. was 56.07%.
Turn-on colorimetric sensing of fluoride ions by a cationic triarylborane bearing benzothiazolium
Song, Ki Cheol,Lee, Kang Mun,Kim, Hyungjun,Lee, Yoon Sup,Lee, Min Hyung,Do, Youngkyu Elsevier 2012 Journal of organometallic chemistry Vol.713 No.-
<P><B>Abstract</B></P><P>A cationic triarylborane Lewis acid bearing benzothiazolium moiety, 2-(4′-dimesitylborylphenyl)-3-methylbenzo[<I>d</I>]thiazol-3-ium ([<B>2</B>]<SUP>+</SUP>) was prepared from a neutral borane (<B>2a</B>) and their crystal structures were determined from X-ray diffraction studies. While <B>2a</B> shows a blue-shift with a small decrease in the UV–vis absorption band upon fluoride binding to the boron atom, [<B>2</B>]<SUP>+</SUP> undergoes a red-shift of the absorption band which tails over visible region, giving rise to the color change of the solution from colorless to yellow. The fluoride binding constant in THF/H<SUB>2</SUB>O (9/1, v/v) is calculated to be 1.3 × 10<SUP>4</SUP> M<SUP>−1</SUP> that is much greater than that of a neutral borane <B>2a</B> (<I>K</I> = 4.2 × 10<SUP>2</SUP> M<SUP>−1</SUP>). DFT calculation results suggest that the absorption process in the fluoroborate (<B>2</B>F) is involved with π(Mes)→π*(phenylbenzothiazolium) intramolecular charge transfer and the greater elevation of the π(Mes) donor level is responsible for the turn-on colorimetric response of [<B>2</B>]<SUP>+</SUP>.</P> <P><B>Graphical abstract</B></P><P>A cationic triarylborane Lewis acid bearing benzothiazolium moiety ([<B>2</B>]<SUP>+</SUP>) was prepared and characterized. [<B>2</B>]<SUP>+</SUP> displays enhanced fluoride ion affinity and turn-on colorimetric response toward fluoride.<ce:figure id='dfig1'></ce:figure></P><P><B>Highlights</B></P><P>► A novel cationic triarylborane Lewis acid was synthesized. ► Fluoride ion affinity was significantly enhanced. ► Fluoride binding led to turn-on color change from colorless to yellow.</P>
갑상선 미세침흡인세포검사 슬라이드에서 BRAF Mutation 검출을 통한 갑상선 유두암의 진단
박원서<SUP>1<,SUP>,이규언<SUP>2<,SUP>,송정윤<SUP>1<,SUP>,정유승<SUP>3<,SUP>,김훈엽<SUP>4<,SUP>,고석환<SUP>1<,SUP>,윤여규<SUP>2,5<,SUP>,Won Seo Park,<SUP>1<,SUP>,Kyu Eun Lee,<SUP>2<,SUP>,Jeong Yoon Song,Ph,D,<SUP>1<,SUP>,Y 대한갑상선-내분비외과학회 2010 The Koreran journal of Endocrine Surgery Vol.10 No.1
Purpose: The prevalence rate of the BRAF mutation in papillary thyroid cancer (PTC) is as high as about 52 to 83% in Korea. Preoperative detection of BRAF mutation on fine needle aspiration cytology (FNAC) slides may help the surgeon make better therapeutic decisions. The present study aims to assess the feasibility of the mutant allele specific amplification (MASA) and restriction fragment length polymorphism (RFLP) method with using conventional FNAC slides and we also wanted to evaluate the clinical role of preoperatively detecting BRAF mutation. Methods: We extracted the genomic DNA from 59 FNAC slides and performed direct sequencing (DS) for detecting BRAF mutation. We could use only 17 slides for the MASA method and 6 slides for the RFLP method due to the shortage of extracted DNA. Additionally, we retrospectively analyzed the cases for which a histological diagnosis could be made. Results: Genomic DNA was extracted from 23 out of the 59 FNAC slides. The BRAF mutation status could be assessed via DS in 33 out of the 59 FNAC slides. The concordance between the MASA method and DS and the RFLP method and DS was 36.3% and 66.7% respectively. The positive and negative predictive value of the 13 indeterminate nodules was 87.5% and 20%, respectively. We could not find any association between the BRAF mutations and the alleged risk factors of PTC. Conclusion: We believe that the purity and the amount of the DNA template must be increased to detect BRAF mutation with using a FNAC slide. Preoperative detection of the BRAF mutation on a FNAC slide may refine the cytological diagnosis, but the application of assessing BRAF mutation as a prognostic marker is debatable. (Korean J Endocrine Surg 2010;10:12-18)
Yoon, Jong Hyun,Roh, Eun Youn,Shin, Sue,Jung, Nam Hee,Song, Eun Young,Lee, Dong Soon,Han, Kyou Sup,Kim, Joung Sung,Kim, Byoung Jae,Jeon, Hye Won,Yoon, Kang Sup Kluwer Academic Publishers 2009 Biotechnology letters Vol.31 No.3
<P>The human umbilical cord (hUC) is a source of adult tissue-derived mesenchymal stem cells (MSCs). A pulsed low-intensity ultrasound (PLIUS) method is described for increasing the yield of MSCs from whole hUC without enzymatic digestion or growth factor supplementation. Analysis of the immunophenotype of cells and a differentiation study were performed to show the compatibility of MSCs. The mean number of cells recovered from primocultures of hUC was 6 x 10(5) cells/cm. PLIUS resulted in a 3.3-fold increase in MSC yield at passage 0. PLIUS exposure increases the yield of hUC-MSCs by promoting release and enhancing proliferation.</P>
송윤섭(Yoon Sup Song) 한국가구학회 2020 한국가구학회지 Vol.31 No.3
Providing a comfortable space through air quality management and sterilization in multi-purpose facilities, and suggesting a new concept of a smart clean bench by showing an example of a bench design that combines the beauty of relaxation and space. The Smart Clean Bench is designed to improve the quality of life by providing comfortable space and the health protection effect of users through the merging of the existing air purification device and the fine dust reduction device of the sterilization system and a bench that can rest. In the future, many design products in which environment and advanced technology are well fused in more living spaces should be developed.
곡목기법을 활용한 스마트클린가구 디자인 연구 -목재형 공기청정기 디자인 중심으로-
송윤섭(Yoon Sup Song) 한국가구학회 2022 한국가구학회지 Vol.33 No.1
Smart clean furniture in the Bentwood Technique was proposed as a fusion design product for the post-corona era, which is experiencing great difficulties by designing the quality of life through the beautiful fusion of the fine dust reduction device of the existing air purification device and sterilization system and the indoor space in the organic form to improve the quality of life by providing comfortable space as well as the health protection effect of the user. The recent life trend is seeking eco-design-based companies that try to improve environmental problems with eco-friendly products, and seek ways to coexist with nature and humans. The wooden air purifier design is environmentally friendly, and it is an organic type of wood product with the fine dust reduction device of the existing air purifier and sterilization system.
창살문양과 LED조명의 병치(倂置) 혼합적 특성을 적용한 가구디자인 연구
송윤섭(Yoon Sup Song) 한국가구학회 2013 한국가구학회지 Vol.24 No.2
The purpose of this research is to provide new direction on the field of the furniture design and to establish the identity of Korean furniture design as the flow of craft’s juxtapose mixture era where it mix and match Korean traditional craft style materials with the modern furniture design. In other words, it is intended to create new furniture design and propose beautiful Korean luxury furniture design based on the precious unique culture with the traditional craft style, juxtaposition of modern furniture, and reinterpretation. It should grant artistic values that can satisfy consumers having various tastes and scarcity values, plus it should put out aesthetic and creative expressions in furniture design putting into the beautiful traditional craft form values. Furthermore, it is required to create new design through values and spirit, materials, techniques, forms, pattern, and usages by interacting, coordinating, and combining tradition and modern East and West, plus craft and design.
전통목가구와 현대소재의 병치(倂置)혼합적 특성을 적용한 가구디자인 연구
송윤섭(Yoon Sup Song) 한국가구학회 2014 한국가구학회지 Vol.25 No.4
The purpose of this research is to provide new direction on the field of the furniture design and to establish the identity of Korean furniture design as the flow of craft’s juxtapose mixture era where it mix and match Korean traditional craft style materials with the modern furniture design. In other words, it is intended to create new furniture design and propose beautiful Korean luxury furniture design based on the precious unique culture with the traditional craft style, juxtaposition of modern furniture, and reinterpretation. It should grant artistic values that can satisfy consumers having various tastes and scarcity values, plus it should put out aesthetic and creative expressions in furniture design putting into the beautiful traditional craft form values. Furthermore, it is required to create new design through values and spirit, materials, techniques, forms, pattern, and usages by interacting, coordinating, and combining tradition and modern East and West, plus craft and design.
송윤섭(Yoon Sup Song) 한국가구학회 2017 한국가구학회지 Vol.28 No.4
Recently, as changes in the office environment, office furniture are changing at a rapid pace. With the development of various smart devices specialized in work type, the concepts of office environment and office furniture are diversified. New furniture design is presented with the new concept of work format and changes to the space, an example of a compact single-person storage space is required.