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Study of the Optimal Film Structure by Using Conventional Elipsometry
Liang-Yao Chen,Ming-Yu Sheng,Yun-Hua Wu,Yuan Zhao,Yue-Rui Chen,Yu-Xiang Zheng 한국물리학회 2008 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.53 No.2
The optimal film structure affected by the space effect has been studied for SiO2 film samples deposited onto Si wafers by using the e-beam evaporation method. The ellipsometric data were measured at different incidence angles and in the 300-800-nm wavelength range. In the range where the phase delay δ is close to π, the film thickness deduced from the conventional ellipsometry model varied with the phase delay. The optimal SiO2 film-thickness was achieved with a modified ellipsometric model, including the space effect. The results given in this work can generally be applied to other optical measurement methods used to study film structures.
Chen, Ying,Fan, Xue-Yun,Jin, Yu-Lan,Yao, San-Qiao,Yun, Xiang,Hua, Zheng-Bing,Shen, Fu-Hai Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20
Background: To explore the relationship between polymorphisms of interleukin17 (IL-17) gene(A-832G 7488A/G) and the susceptibility to silicosis, a risk factor for lung cancer. Materials and Methods: A total of 113 silicosis patients and 116 workers without silicosis were enrolled in the case-control study. IL-17A A-832G and IL-17F 7488A/G polymorphisms were evaluated by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Results: The frequencies of AA,GG and AG of IL-17A A-832G locus in the case and control groups were 46.9%, 8.0%, 45.1%, and 49.2%, 7.6%, 43.2%, respectively, with no significant differences (p>0.05).The GG genotype in the IL-17F (7488A/G) locus was not found. The frequencies of AA and GA of IL-17F 7488A/G locus in the case and control groups were 84.1%, 15.9% and 66.4%, 33.6%, respectively (p<0.05). Analysis of combined effects showed that the individuals with GG+AG genotype of IL-17A and GG+GA genotype of IL-17F are protected against silicosis (OR=0.469). Conclusions: IL-17F 7488A/G is associated with susceptibility to silicosis, and G allele may have a protective effect. No relationship was found between IL-17A gene polymorphisms at A-832G and silicosis.
A new piezoelectric shell element and its application in static shape control
Chen, Su Huan,Yao, Guo Feng,Lian, Hua Dong Techno-Press 2001 Structural Engineering and Mechanics, An Int'l Jou Vol.12 No.5
In this paper, a new three-dimensional piezoelectric thin shell element containing an integrated distributed piezoelectric sensor and actuator is proposed. The distributed piezoelectric sensor layer monitors the structural shape deformation due to the direct effect and the distributed actuator layer suppresses the deflection via the converse piezoelectric effect. A finite element formulation is presented for static response of laminated shell with piezoelectric sensors/actuators. An eight-node and forty-DOF shell element is built. The performance of the shell elements is improved by reduced integration technique. The static shape control of structure is derived. The shell element is verified by calculating piezoelectric polymeric PVDF bimorph beam. The results agreed with those obtained by theoretical analysis, Tzou and Tseng (1990) and Hwang and Park (1993) fairly well. At last, the static shape control of a paraboloidal antenna is presented.
Yao Long,Jun-hua Chen,Jia-sheng Zhang 대한토목학회 2017 KSCE Journal of Civil Engineering Vol.21 No.7
A damage strain softening model for predicting the shear behavior of soil–structure interfaces is presented. The damage model, which contains only four parameters (i.e., undamaged shear modulus G′, damage evolution parameters n and m, and the residual shear stress τr), is developed based on Weibull distribution statistical damage theory. By fitting curves, the model parameters are obtained from director simple shear tests. As the shear thickness is usually considered an important factor on soil–structure interface constitutive relations, the shear thickness ratio (η) is introduced to the model to compensate for the influence of the shear thickness. The relationships between the model parameters and the shear thickness ratio η are also analyzed under different levels of normal stress based on data from both direct and simple shear tests. The results show that the undamaged shear modulus G′ increases with increasing normal stress and increasing shear thickness. The shear thickness has a significant effect on the damage evolution parameter n, but the normal stress does not. Neither normal stress nor shear thickness have significant effects on the damage evolution parameter m. The residual shear stress τr increases with increasing normal stress.
Chen, Xin-Ping,Xu, Wei-Hua,Xu, Da-Feng,Xie, Xian-He,Yao, Jia,Fu, Sheng-Miao Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.18
Although a number of studies have been conducted on the association between GSTM1 polymorphisms and lung cancer in China, this association remains elusive and controversial. To clarify the effects of GSTM1 polymorphisms on the risk of lung cancer, a meta-analysis was performed in the Chinese population. Related studies were identified from PubMed, Springer Link, Ovid, Chinese Wanfang Data Knowledge Service Platform, Chinese National Knowledge Infrastructure (CNKI), and Chinese Biology Medicine (CBM) up to 5th April 2014. A total of 45 articles (47 studies) including 6,623 cases and 7,865 controls were involved in this meta-analysis. Overall, a significant association (OR = 1.45, 95%CI: 1.32-1.60) was found between the null GSTM1 and lung cancer risk when all studies in Chinese population pooled into the meta-analysis. In subgroup analyses stratified by quality score, geographic area and source of controls, the same results were observed under all the models. This meta-analysis showed that the null GSTM1 may be a potential biomarker for lung cancer risk in Chinese, but further studies with gene-gene and gene-environment interactions are required for definite conclusions.
Significance of Caveolin-1 Regulators in Pancreatic Cancer
Chen, Tao,Liu, Liang,Xu, Hua-Xiang,Wang, Wen-Quan,Wu, Chun-Tao,Yao, Wan-Tong,Yu, Xian-Jun Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.8
Caveolin-1 is a scaffold protein on the cell membrane. As the main component of caveolae, caveolin-1 is involved in many biological processes that include substance uptake and transmembrane signaling. Many of these processes and thus caveolin-1 contribute to cell transformation, tumorigenesis, and metastasis. Of particular interest are the dual rolesof tumor suppressor and oncogene that caveolin-1 appear to play in different malignancies, including pancreatic cancer. Therefore, analyzing caveolin-1 regulators and understanding their mechanisms of actionis key to identifying novel diagnostic and therapeutic tools for pancreatic cancer. This review details the mechanisms of action of caveolin-1 regulators and the potential significance for pancreatic cancer treatment.