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( Youngwoo Jang ),( Heekyung Ahn ),( Eunyoung Kim ),( Jungkeun Moon ),( Yangbin Jeon ),( Kyuchan Lee ),( Yeonho Park ),( Eunyoung Cho ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Primary cardiac cancer is a very rare disease, as the prevalence is 0.001 to 0.03%. Primary cardiac angiosarcoma is one of the most frequent types of primary cardiac cancers, however, is characterized by extremely poor prognosis, as the mean survival is reported to be only three to four months, and optimal treatment is unknown. Here we report a patient of primary cardiac angiosarcoma with hemorrhagic pericardial effusion who achieved a durable response with tumor excision followed by concurrent chemoradiotherapy with docetaxel. A sixty year old male with underlying history of diabetes mellitus presented with rapidly progressing shortness of breath. Cardiac tamponade was diagnosed, and 420 cc of bloody fiuid was drained with pericardiocentesis. The patient`s blood pressure was restored to within normal limit after pericardial effusion drainage. Subsequent chest computed tomography scan, echocardiography and cardiac Magnetic Resonance Image revealed a 4.5x3.5cm sized infiltrative mass in the right atrium. Tumor excision was performed, of which pathologic findings revealed cardiac angiosarcoma with tumor involvement of resection margin. The patient underwent adjuvant radiotherapy (5000cGys/30fractions) with concurrent chemotherapy with docetaxel. There was no evidence of recurrence until ten months later, when multiple liver metastases were found on CT scan. Hepatic metastasectomy with periop chemotherapy with weekly paclitaxel was followed. As of Jul 2014, the patient is receiving chemotherapy with overall survival of 16 months and counting. Currently there are only three published case reports of cardiac angiosarcoma which showed response to radiation and taxane, and this is the fourth case report of successful treatment. Further investigation on this regimen is warranted.
Trauma Volume and Performance of a Regional Trauma Center in Korea: Initial 5-Year Analysis
( Byungchul Yu ),( Giljae Lee ),( Min A Lee ),( Kangkook Choi ),( Sungyoul Hyun ),( Yangbin Jeon ),( Yong-cheol Yoon ),( Jungnam Lee ) 대한외상학회 2020 大韓外傷學會誌 Vol.33 No.1
Purpose: We aimed to evaluate the trauma volume and performance indicators during the first 5-year period of operation in a single regional trauma center. Methods: We analyzed prospectively collected data from the Korean Trauma Data Bank for a single regional trauma center between January 2014 and December 2018. More than 250 variables were analyzed. We calculated the predicted survival rates using the trauma and injury severity score (TRISS) method. Results: In total, there were 16,103 trauma admissions during the first 5 years; trauma activation was performed in 5,105 of these cases. Over 70% of the patients were men, and most of the admitted patients were within the age groups of 55-59 years for men and 75-79 years for women. Analyses were performed considering two patient groups: the total patient group and the group of those with severe trauma (injury severity score [ISS] >15). The median ISS, revised trauma score, and TRISS of the two groups were 5 (interquartile range [IQR] 4-10), 22 (IQR 17-27), and 7.6±0.99 and 6.74±1.9, 0.95±0.13, 0.81±2.67, respectively. Of the total patient group, 801 patients (5%) died in the hospital, whereas of the group of patients with ISS >15, 526 (19.5%) died. The direct transportation of patients to the regional trauma center increased year by year. The emergency room stay time and time to entering the operating room showed a decrease until 2017; however, these parameters increased again in 2018. Conclusions: The trauma volume in the regional trauma center is appropriate, and some improvements could be observed after its establishment. However, performance indicators reveal the prematurity of the trauma center and its potential for further improvements. Moreover, the development of a national trauma system, beyond regional trauma centers, is required.