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RISS 인기검색어
- 검색키워드
- 저자 : ( Y Dahgwahdorj ) (검색결과 3 건)
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Baatarkhuu, Oidov,Kim, Do Young,Ahn, Sang Hoon,Nymadawa, Pagvajav,Dahgwahdorj, Yagaanbuyant,Shagdarsuren, Manaljav,Park, Jun Yong,Choi, Jong Won,Oyunbileg, Janchiv,Oyunsuren, Tsendsuren,Han, Kwang Hyu Blackwell Publishing Ltd 2008 Liver International Vol.28 No.10
<P>Abstract</P><P>Background and Aims</P><P>Hepatitis C virus (HCV) is one of the major causes of liver cirrhosis and hepatocellular carcinoma (HCC) in Mongolia. However, there are no data concerning nationwide prevalence of HCV infection in Mongolia. We intended to investigate the population-based prevalence of HCV infection and genotype distribution among 1512 apparently healthy individuals in this country.</P><P>Methods</P><P>Between April 2003 and December 2005, sera from 1512 residents of Ulaanbaatar and 12 provinces were collected by two-stage cluster random sampling, and anti-HCV was tested. Anti-HCV-positive samples were tested for HCV RNA by reverse transcription polymerase chain reaction, and HCV genotype was determined.</P><P>Results</P><P>The mean age of the subjects was 46.2±17.8 years, and 812 (53.7%) were male. Overall, the prevalence of anti-HCV was 15.6% (236/1512) and HCV RNA was detected in 167 subjects (11.0%), with the most common genotype being 1b (165/167, 98.8%). When the HCV RNA-positive subjects were categorized by decade of age, the prevalence in each age group was as follows: 2.5% in subjects ≤10 years of age, 4.5% in teens, 10.1% in 20's, 12.5% in 30's, 24.2% in 40's, 29.0% in 50's and 32.6% in subjects ≥61 years of age. The seroprevalence of anti-HCV in a risk group, nurses, was not significantly different from the general population in each decade of age (<I>P</I>>0.05).</P><P>Conclusions</P><P>Approximately 11.0% of apparently healthy population had detectable HCV RNA in Mongolia, and the predominant genotype of HCV was 1b. Preventive and therapeutic strategies for chronic hepatitis C are urgently warranted in this HCV-endemic area.</P>
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( O Baatarkhuu ),( Do Young Kim ),( B Bayarmagnai ),( N Khorolsuren ),( B Baigal ),( R Ouyngerel ),( D Enkhsaikhan ),( Y Dahgwahdorj ),( Sang Hoon Ahn ),( Kwang Hyub Han ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1
Background and Aims: Mongolia is an endemic area of acute and chronic viral hepatitis. To determine the prevalence of HAV, HBV, HCV and HDV infections among patients with acute hepatitis in Mongolia during outbreaks. Methods: A total of 624 patients (353 males and 271 females; age, 18.6±8.1 years; range 2-66 years) who were clinically diagnosed with acute hepatitis during outbreak from October 2011 to March 2012 in Ulaanbaatar, Mongolia have been studied. The prevalence of hepatitis virus infections was determined by testing of serum for the IgM class of antibodies against HAV, HBV, HCV, HDV, and HBsAg. Results: Acute hepatitis A (AHA) (IgM anti-HAV positive) was diagnosed in 284 patients (45.5%). Acute hepatitis B (AHB) (IgM anti-HBc positive) was diagnosed in 191 patients (30.6%) and 22 patients (3.5%) was diagnosed as co-infection of B and D. Acute hepatitis C (AHC) (IgM anti-HCV positive) was diagnosed in 33 patients (5.3%). There were 52 (8.3%) HBV carriers who had detectable HBsAg and anti-HDV but who were negative for both IgM anti-HAV and IgM anti-HBc, suggesting that they acquired type D acute hepatitis due to superinfection of HDV on a background of chronic HBV infection. Forty-two (6.5%) patients were found to be infected by various combinations of dual viruses such as HAV/HBV (2.8%), HAV/HDV (0.6%), HBV/HCV (2.5%), and HCV/HDV (0.6%). AHA was the most prevalent in subjects aged 1-19 years, AHB and HBV+HDV superinfection were the first and second most prevalent in the age group of 20-29 years, and AHC was the most common type in 40-49 years. Conclusion: Dual hepatitis viral infection was detected in approximately 6.5% among patients with acute hepatitis in Mongolia.
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( O. Baatarkhuu ),( Do Young Kim ),( B Bayarmagna ),( N Khorolsuren Baigal ),( R Ouyngerel ),( D Enkhsaikhan ),( Y Dahgwahdorj ),( Sang Hoon Ahn ),( Kwang Hyub Han ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.-
Background and Aims: Mongolia is an endemic area of acute and chronic viral hepatitis. To determine the prevalence of HAV, HBV, HCV and HDV infections among patients with acute hepatitis in Mongolia during outbreaks. Methods: A total of 624 patients (353 males and 271 females; age, 18.6±8.1 years; range 2-66 years) who were clinically diagnosed with acute hepatitis during outbreak from October 2011 to March 2012 in Ulaanbaatar, Mongolia have been studied. The prevalence of hepatitis virus infections was determined by testing of serum for the IgM class of antibodies against HAV, HBV, HCV, HDV, and HBsAg. Results: Acute hepatitis A (AHA) (IgM anti-HAV positive) was diagnosed in 284 patients (45.5%). Acute hepatitis B (AHB) (IgM anti-HBc positive) was diagnosed in 191 patients (30.6%) and 22 patients (3.5%) was diagnosed as co-infection of B and D. Acute hepatitis C (AHC) (IgM anti-HCV positive) was diagnosed in 33 patients (5.3%). There were 52 (8.3%) HBV carriers who had detectable HBsAg and anti-HDV but who were negative for both IgM anti-HAV and IgM anti-HBc, suggesting that they acquired type D acute hepatitis due to superinfection of HDV on a background of chronic HBV infection. Forty-two (6.5%) patients were found to be infected by various combinations of dual viruses such as HAV/HBV (2.8%), HAV/HDV (0.6%), HBV/HCV (2.5%), and HCV/HDV (0.6%). AHA was the most prevalent in subjects aged 1-19 years, AHB and HBV+HDV superinfection were the first and second most prevalent in the age group of 20-29 years, and AHC was the most common type in 40-49 years. Conclusion: Dual hepatitis viral infection was detected in approximately 6.5% among patients with acute hepatitis in Mongolia.
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