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        Study on the Characteristics of X-ray Spectra in Imaging Diagnosis Using Monte Carlo Simulations

        Khanh Ai Tran,Loan Thi Hong Truong,Nhon Van Mai,Phuong Nguyen Dang,Dung Thi Thuy Vo 한국물리학회 2016 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.69 No.7

        X-rays are widely used in diagnostic imaging such as radiography and computed tomography. An understanding of the X-ray spectrum is essential for estimating the dose absorbed by the patient and for improving image quality. In this research, X-ray emission spectra were investigated by using two different approaches: a Monte Carlo method using the MCNP5 code and a semi-empirical calculation with SpekCalc software. The results were compared with each other to validate the Monte Carlo simulation of the X-ray spectra, so that the simulation model can be applied to estimating the dose rate distribution in X-ray imaging. The obtained results show good agreement between the two approaches, but some divergence is still observed in the characteristic X-ray peaks. In addition, the influence of X-ray tube parameters such as the peak voltage, filter, anode angle and target material on of the beam quality was investigated.

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        Chitosan Oligomer as a Hopeful Adjuvant for H5n1 Influenza Vaccine

        ( Le Van Hiep ),( Mai Thi Thanh ),( Dang Thi Hong Van ),( Vo Thi Phuong Khanh ),( Nguyen Anh Dzung ) 한국키틴키토산학회 2008 한국키틴키토산학회지 Vol.13 No.1

        Effect of Chitosan oligomer (dp = 8-16) and other adjuvant such as: Aluminum phosphate (AlPO4) and Freund on immune response of H5N1 influenza vaccine in Swiss mice has been investigated. The Swiss mice were twice vaccinated alternative 20 days with dose 0.1 ml/mouse. After 10, 20 and 30 days, the immune response of Swiss mice with H5N1 vaccine was detected. The result showed that after 20 days of the first vaccination, immune response of chitosan oligomer test and Freund was 100%, but Freund test reduced 80% after 30days of vaccination. Meanwhile, immune response of the control and AlPO4 test was very low, only 40%. The Effect of chitosan oligomer and the others on antibody titer has been also investigated. The result showed that the antibody titer of chitosan oligomer test was 60 HIU (Hemagglutination units), 70 HIUs after 10 and 20 days of the first vaccination, and increased up to 112 HIUs after 10 days of the second vaccination and the antibody titer of the chitosan oligomer test was higher than the others. Therefore, chitosan oligomer is a hopeful adjuvant for H5N1 influenza vaccine.

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        Efficacy of electrochemically activated water solution in gingivitis treatment

        Dinh‑Toi Chu,Van‑Huy Pham,Thien Chu‑Dinh,Truong Nhu Ngoc Vo,Duc Long Duong,Van Nhon Bui,Minh Son Tong,Thi Thu Phuong Nguyen,Quynh Anh Le,Khanh‑Hoang Nguyen 한국약제학회 2019 Journal of Pharmaceutical Investigation Vol.49 No.3

        Mouthwash is one of the most commonly oral healthcare products for prevention and treatment of gum diseases. Dr. ECA is a disinfectant solution manufactured by a Vietnamese company and has been licensed for oral healthcare, but its effect on gingivitis is still unclear. To evaluate the effectiveness of this product in the treatment of gingivitis, we conducted a clinical study in 60 students diagnosed with gingivitis to compare the results of gingivitis treatment using Dr. ECA and a control mouthwash (a demonstrated anti-gingivitis product). The data showed that in the treated group, the rate of good Gingivitis Index (GI) before treatment was 46.67%, but after 2 and 4 weeks of using Dr. ECA that rate was increased to 96.67% and 100%, respectively. The percentage of patients with bleeding on probing was 63.33% but declined sharply after 2 weeks of treatment to 6.67%, and further reduced to 3.33% after 4 weeks of treatment. The treatment outcomes in were similar in the Dr. ECA treated group and control one with no statistically significant difference. Our results suggest that the electrolyte saline solution Dr. ECA is effective in treating gingivitis. Its effects are similar to other mouthwash products that had been approved and marketed.

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