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      • 癩腫性癩의 血流中에 癩菌檢索에 關한 硏究

        金重明,申先伊,徐城鐸,徐治均 慶北大學校 1964 論文集 Vol.8 No.-

        Although It was Introduced that the Mycobacterium leprae was investigated in circulatory blood of leprosy patients. In recent, Naniwa(1938) had depicted that there were intimate relationship between the grade of disease and bacillary number in the blood stream, Nagata (1953) had described that the humber of leprosy bacilli in circulatory blood were diminshed by the appropriate leprocy treatment, and Obshima(1957) have suggested that leprosy bacilli in blood stream were closely related with the fundamental problem of pracental infection and onset of untainted children from leprosy patients. In order to investigate this point further, we have tested 211 cases of lepromatous leprosy patients and this observation gave us as following results' 1. We could find out the Mycobacterium leprae in 0,08㎖ of circulatory blood from lepromatous leprosy patient. 2. The bacilli positives were more than 90% in the case of untreated patients and most of them were presented in the monocyte and polymorphonuclear cell. 3. The bacillary numbers were greatly decreased by the treatment, and after 9 months more over begining trearment, it was turned to be complete negative. 4. There were close relation between the bacillary number and grade of disease, but no relation in lepromin and tuberculin reaction. 5. In E.N.L. the bacillus was negative, and 1 of 4 cases was positive in acute infiltration. 6. we think that the bacilli in blood stream of leprosy patient will be a new aspect in the study of the pracental infecton and untained children of leprosy patient.

      • 백서 대장암의 동종면역효과에 관한 연구 : Effect of Cancer Bearing Rat Serum

        김형일,박애자,장선택 중앙대학교 의과대학 의과학연구소 1988 中央醫大誌 Vol.13 No.2

        In recent years, there has been much interests in identification and characterization of numerous tumor relating substances including ectopic hormones, oncofetal antigens, or abnormal enzymes for the diagnosis and monitoring of malignant tumors. But, practically so called cancer antigen, such as AFP, CEA, or TPA, which has been never used toward manufacturing anti-cancer antibody, while only used to compete the cancer tissue type specificity. Nowadays, cancer antigen must be actually applied in the field of cancer treatment by means of the mediator or inducer for anti-cancer antibody formation. This study researched the alloimmunization effect of the serum components obtained from cancer developing animals, chemical carcinogen (NG: N-methyl-N'-nitroso-N-nitrosoguanidine) induced colon adenocarcinoma model, in 216 male rats, and gained following results: 1. In cancer producing rats, the CRP levels were maintained evenly high values althrough the experimental period, but serum TPA was gradually increased along sequential studies, while βCG and LDH were increased in early acute phase and sooner decreased in late phase. 2. The individuals, those were alloimmunized by the serum acquired from cancer bearing rats, represented significantly high cancer rejection rate, especially in the group which was infused the serum of conspicuously high TPA concentration. 3. In the long survivers and cancer resistance group, could observed neither high βCG level nor increased LDH value, however the early deaths revealed extremely higher βCG and LDH levels in contrast of relatively lower TPA concentration. 4. So, there was able to confirm the fact that not only cancer rejection antigenicity was presented in the serum of cancer developing individuals, but also could gained prominent allommunization effect utilizing such serum of high occurring TPA believing one of immunologic cancer rejectives by itself or mediation of antibody inducing effects.

      • 마우스 골수세포의 액체배양에서의 세포화학적 염색성에 관한 연구

        김현태,박애자,장선택 중앙대학교 의과대학 의과학연구소 1988 中央醫大誌 Vol.13 No.4

        The mouse bone marrow cells were cultured in liquid culture system to investigate the correlation of cytochemical changes and the number of colony forming unit granulocyte/macrophage(CFU-GM) and colony-forming unit megakaryocyte(CFU-Meg) colonies with cell maturation and platelet formation. The following results are obtained; 1. Total colony counts are markedly increased during 4-6 days of culture and reach the maximum number by 7th day (262.33 ± 192.33/ml). The number of cells are increased in each colonies without increase of total colony number after 5 days. 2. The mean ratio of acetylcholinesterase positive megakaryocyte colonies are 13.70 ± 7.04% of total colonies formed with no remarkable changes during 9 days culture period. The number of megakaryocyte colonies reach maximum level by 7th day (31.37 ± 25.73/ml), while that of nonmegakaryocytic colonies reach maximum level by 9th day (230.51 ± 81.90/m1). 3. Platelet count in medium are 5,000 ± 3,490/ml with no remarkable changes during 9 days of culture periods. 4. In acetylcholinesterase positive megakaryocytic colonies, the PAS stain show weak positive in few megakaryocyte by 3rd day, however about 40% of megakaryocytes show rather strong positivity by 7th day. The positivity of non-specific esterase and acid phosphatase are less than 10% until 9th flay of culture. Specific esterase positivity was not found during 9 days period of culture. 5. Non-specific esterase and acid phosphatase stain show lower positivies (11%, 5%) than PAS and specific esterase stain (21%, 55%) in non megakaryocyte colonies. In summary, the number of CFU-GM and CPU-Meg colonies in liquid culture are increased gradually and reached maximum by 7th day, forming large colonies from 5th days on In megakaryocytic colonies, no evidence of platelet formation were observed during 9 days period of culture. It is suggesed that the majority of CFU -GM colonies in liquid culture are mixed colonies according to the cytochemical stainabilities.

      • SCOPUS

        Geometric Accuracy Measurement of Machined Surface Using the OMM (On the Machine Measurement) System

        Kim, Sun-Ho,Lee, Seung-Woo,Kim, Dong-Hoon,Lee, An-Sung,Lim, Sun-Jong,Park, Kyoung-Taik Korean Society for Precision Engineering 2003 International Journal of the Korean Society of Pre Vol.4 No.4

        Machining information such as form accuracy and surface roughness is an important factor for manufacturing precise parts. To this regard, OMM (On the Machine Measurement) has been researched for last several decades to alternate CMM (Coordinate Measurement Machine) process. In this research, the OMM system with a laser displacement sensor was developed for measuring form accuracy and surface roughness of the machined workpiece on the machine tool. The surface roughness was estimated comparing the sensory signal with the reference data measured from master specimen. Also, form accuracy was determined from the moving averaged raw data. In addition, the geometric error map constructed beforehand using the geometric errors of the machine tool was used to compensate the obtained form accuracy. The overall performance was compared with CMM result, and verified the feasibility of the measurement system.

      • SCIEKCI등재
      • Optimization of parameters for the synthesis of bimodal Ag nanoparticles by Taguchi method

        Kim, Sang Min,Park, Ki Sun,Kim, Ki Do,Park, Sung Dae,Kim, Hee Taik Elsevier 2009 Journal of industrial and engineering chemistry Vol.15 No.6

        <P><B>Abstract</B></P><P>Bimodal Ag nanoparticles were synthesized by modified precipitation process. Taguchi analysis was used in this study and the reaction time and temperature were the most influencing parameter on the particle size and the size distribution, respectively. The optimal conditions were determined by using Taguchi method and nano-sized Ag particles with bimodal shape were obtained.</P>

      • The Solution of a Forced Unamped Harmonic Oscillator Under the Various Restrictions

        Kim, Sun Kyu,Kim, Chun Taik 成均館大學校 1965 論文集 Vol.10 No.-

        本 論文에서는 場理論方法에 依하여 求할 수 있는 强制非減衰調和振動子에 對한 解를 適當한 除限條件밑에서 散亂行列方法을 使用하여 求하였다. 이때 除條件으로 振動子에 作用하는 driving force F(t)가 거의 無視될 때 振動子는 無限한 時間동안 振動할 것이란 假定을 두었고 driving force F(t)의 Fourier 變換이 存在한다는 條件을 두었다. 調和振動子에 對한 遷移確率은 散亂行列要素들은 Heisenberg States와 operators들로서 表示한 Laguerre 多項式으로 表示한 結果를 얻었다. 그리고 振動子에 傳導된 平均 Energy는 初期狀態에는 關係없고 共鳴의 境遇에 있어 入射波가 共鳴振動數 ω에 近方에서 連續的인 Energy 分布를 나타내는 古典的 振動子의 結果와 잘 一致함을 보여 주고 있다. 따라서 이른 基本的인 場理論에 이른 方法의 應用은 particle이 바로 그들에 對應하는 Current로 變換하는 現代場論의 Contraction method의 簡單한 한 例로서 基礎場論硏究에 기여될 것으로 믿는다. In this paper, the exact solution for the forced undamped quantum harmonic ocsillator can be obtained by S-marix technique under the proper condition and hypothesises as much as to obtain by the field theory technique have been investigated in full detail. It is assumed that the oscillator will vibrate for an infinitely long time(t=±∞) provided the driving force F(t) is neglected. The only restriction is that the Fourier transform of F(t) must exist. The transition probabilities for the oscillator are obtained in closed form in terms of Lagurre polynomials by expressing S-matrix elements as Heisenberg states and operators. The mean energy transfer from the incident wave to the oscillator is found not to be dependent of the initial state, and is in agreement with the classical results which, in the case of resonance, was obtained when the primary radiation was assumed to have a continuous energy distribution in the neighbourhood of resonant frequancy ω. The application of this techniques to this fundamental field theoretical model provides a simple example of the contraction method of modern field theory where-by particles are converted into their corresponding currents.

      • KCI등재후보

        Separation of the Tip of a Coblation Wand within the Knee Joint: A Complication of Arthroscopic Adhesiolysis

        Yeub Kim,Ha-Kyung Kim,Jung-Ro Yoon,Nasir Muzaffar,Taik-Sun Kim,Young-Su Shin 대한정형외과학회 2010 Clinics in Orthopedic Surgery Vol.2 No.2

        Coblation devices are now widely used in arthroscopic surgery and they show a very low incidence of intraoperative complications. We experienced a case where the tip of the wand separated and migrated into the posterior knee compartment in an arthrofibrotic knee. The free wand tip was identified and then extricated from the popliteal hiatus of the knee with using C-arm fluoroscopic control. To the best of our knowledge, this is the first report of its kind involving coblation wands. We describe this complication to show that the use of coblation devices can lead to unexpected problems and it is imperative to inspect all instruments before and after each surgical use.

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