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박승창,김달식,임채웅,조남표,강명재,이혜수,최호열,김상호 의과학연구소 1994 全北醫大論文集 Vol.18 No.2
Author evaluated specimens of the uterine cervix submitted in Chonbuk National University Hospital laboratory from Sept. 1983 to Aug. 1986. The specimens were diagnosed hitologically under the light microscope previously. The results were as follows ; 1. The analyzed cervical tissues were 982 cases, e.g. 681 cases by punch biopsy, 166 cases by polypectomy, 32 cases by conization, 51 cases by total hysterectomy, 51 cases by radical hysterectomy, and one cases by endocervical curettage. 2. On the hitological classification of the tissue, chronic cervicities and chronic cervicitis with wquamous metaplasia were 483 cases, cervical polyps 164 cases, dyplasia 123 cases, carcinoma in situ 22 cases, microinvasivee carcinoma 6 cases, invasive squamous cell carcinoma 157 cases, adenocarcinoma 13 cases, condyloma accuninaturn 3 cases and verrucous carcinoma was one case. 3. The peak incidence of cervical lesions occurs 5th decade (365cases), and the average was 44.2 year of age. The youngest and oldest cases were 16 and 79 year of age. 4. The average age of chronic cervicitis was 40.6 years, chronic cervicitis with squamous metaplasia was 40.7 years, cervical polyp was 42.9 years, dysplasia was 42.2 years, carcinoma in sity was 42.8 years, microinvasive carcinoma was 49.8 years, invasive squamous cell carcinoma was 48.4 years, and adenocarcinoma was 50.8 years. 5. Clinical manifestation of the patients with performed biopsy of the uterine cervix were leukorrhea(289 cases), vaginal spotting(279 cases), contact bleeding(229 cases), and irregular vaginal bleeding(221 cases). And other many symptoms were complained. 6. Clinical manifestations of the chronic cervicitis and chronic cervicitis with squamous metaplasia were leukorhea, vaginal spotting and contact bleeding, dysplasia was contact bleeding and leukorrhea, and invasive carcinoma was irregular vaginal bleeding, vaginal spotting, and contact bleeding. 7. The main histological diagnosis of the cervical tissues obtained by punch biopsy(681 cases) were chronic cervicitis and squamous metaplasia(442 cases), invasive carcinoma(128 cases), and dysplasia(85 cases). The tissues by polypectomy(166 cases) were diagnosed with polyp(160 cases) mostly, and conebiopsy tissues(32 cases) were disclosed with dysplasia(16 cases) and chronic cervicitis & squamous metaplasia(10 cases). The specimens by total hysterectomy specimens(51 cases) were confirmed with invasive carcinoma(38 cases) mainly.
( Kang Pyo Kim ),( Nam Woo Kwon ),( Beom Kyung Kim ),( Seung Up Kim ),( Do Young Kim ),( Sang Hoon Ahn ),( Kwang Hyub Han ),( Chae Yoon Chon ),( Jun Yong Park ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.-
Background: With wide use of vaccination and antiviral agents against hepatitis B virus (HBV) infection, epidemiologic characteristics of HBV-infected patients have changed substantially for several decades in South Korea, however, recent data are lacking. Hence, we reviewed the recent clinical characteristics of patients with chronic hepatitis B (CHB). Methods: From January 2010 to December 2010, we studied 5,262 consecutive HBV-infected patients who visited in Severance Hospital. Data concerning demographic profiles, laboratory findings about viral activity, and antiviral therapy were gathered. Results: Among the whole population, the median age was 51.0 and 66.0% were male. 1,788 (34.0%) had positive HBeAg and the median ALT level was 31.0 (2, 4700) IU/ml and 1,560 (29.6%) patients had family history of HBV-related liver disease. Regarding viral replication status, 297 (5%) patients were in immune tolerance phase, 2,195 (42%) in inactive phase, and the remaining 2,770 (53%) patients were in active CHB (either immune clearance or reactivation phase). Liver cirrhosis was diagnosed in 2,065 patients, among them, 611 (29.6%) patients had positive HBeAg, and 576 patients had experienced decompensation events including ascites, variceal bleeding, and hepatic encephalopathy. Hepatocellular carcinoma was diagnosed in 1,268 patients. Patients with HCC increased as they get older, especially after age of forty for male and after fifty for female. The male patients had a significantly higher ratio of the HCC than female patients did (78.7% vs. 21.3%, respectively, p<0.001). Conclusions: The study result shows that epidemiologic characteristics of CHB are male, elder, HBeAg negative dominant. The further studies are required to investigate the overall epidemiology of HBV infection in Korea.
Kwang Pyo Chae,Won Oak Choi,Jae-Gwang Lee,Byung-Sub Kang,Seung Han Choi 한국자기학회 2013 Journal of Magnetics Vol.18 No.1
Nickel substituted manganese ferrites, Mn1-xNixFe₂O₄ (0.0 ≤ x ≤ 0.6), were fabricated by sol-gel method. The effects of sintering and substitution on their crystallographic and magnetic properties were studied. X-ray diffractometry of Mn0.6Ni0.4Fe₂O₄ ferrite sintered above 523 K indicated a spinel structure; particles increased in size with hotter sintering. The Mossbauer spectrum of this ferrite sintered at 523 K could be fitted as a single quadrupole doublet, indicative of a superparamagnetic phase. Sintering at 573 K led to spectrum fitted as the superposition of two Zeeman sextets and a single quadrupole doublet, indicating both ferrimagnetic and paramagnetic phase. Sintering at 673 K and at 773 K led to spectra fitted as two Zeeman sextets due to a ferrimagnetic phase. The saturation magnetization and the coercivity of Mn0.6Ni0.4Fe₂O₄ ferrite sintered at 773 K were 53.05 emu/g and 142.08 Oe. In Mn1-xNixFe₂O₄ (0.0 ≤ x ≤ 0.6) ferrites, sintering of any composition at 773 K led to a single spinel structure. Increased Ni substitution decreased the ferrites’ lattice constants and increased their particle sizes. The Mossbauer spectra could be fitted as the superposition of two Zeeman sextets due to the tetrahedral and the octahedral sites of the Fe³? ions. The variations of saturation magnetization and coercivity with changing Ni content could be explained using the changes of particle size.
이승표(Seung Pyo Lee),이나연(Nah Yon Lee),차채영(Chae Yeong Cha),이인하(In Ha Lee),이상률(Sang Roul Lee),김원익(Won Ik Kim),김태우(Tae Woo Kim) 대한기계학회 2012 대한기계학회 춘추학술대회 Vol.2012 No.11
The automotive wheel bearing is one of important components in vehicle to translate the power and bear the weight. Bearing life is affected by many parameters such as bearing geometry, bearing specification, vehicle specification, loading conditions, lubrication conditions, material properties, and so on. In this paper, the optimization of the bearing life was performed using design of experiments. A factorial design was applied to carry out the bearing life calculation proposed by ISO 281:2007 and to investigate the design variables effects influencing on bearing life. The determination of the significance of effects in an experiment was made through the analysis of variance. The results showed that operating temperature and contamination affected the bearing life significantly.
채승희(Seung-Hee Chae),김지민(Ji-min kim),이병화(Byeong-Hwa Lee),홍정표(Jung-Pyo Hong) 대한전기학회 2009 대한전기학회 학술대회 논문집 Vol.2009 No.7
The purpose of this paper is Characteristics Analysis according to thickness of Secondary Conductor in Tubular Linear Induction Motor(TLIM). Linear motors make good used of several applications as pumps and linear actuator. Characteristic equations of TLIM are obtained form voltage equation. And parameters of voltage equation are calculated.
이승화(Seung Wha Lee),이재광(Jae-Gwang Lee),채광표(Kwang Pyo Chae),안성용(Sung Yong An) 한국자기학회 2010 韓國磁氣學會誌 Vol.20 No.5
γ-Fe₂O₃ nanoparticles have been prepared by a sol-gel method. The structural and magnetic properties have been investigated by XRD, VSM and Mossbauer spectroscopy. γ-Fe₂O₃ powder annealed at 150℃ has a spinel structure and superparamagnetical behavior. The estimated size of superparammagnetic γ-Fe₂O₃ nanoparticle is around 7 ㎚. The hyperfine fields at -261℃ for the A and B patterns were found to be 503 and 485 kOe, respectively. The blocking temperature (T<SUB>B</SUB>) of superparammagnetic γ-Fe₂O₃ nanoparticle is about -183℃. The magnetic anisotropy constant of γ-Fe₂O₃ nanoparticle was calculated to be 1.6 × 106 ergs/㎤. γ-Fe₂O₃ nanoparticle annealed at 150℃ can be a candidate for biomedicine applications as magnetic carriers.
Lee, Seung-Pyo,Park, Kyung Woo,Shin, Dong-Ho,Lee, Hae-Young,Kang, Hyun-Jae,Koo, Bon-Kwon,Suh, Jung-Won,Youn, Tae-Jin,Choi, Dong-Ju,Chae, In-Ho,Kim, Hyo-Soo Japan Atherosclerosis Society 2011 Journal of atherosclerosis and thrombosis Vol.18 No.10
<P>Aim: Previous studies regarding on-treatment platelet reactivity have focused on response variability to individual antiplatelet agents. There are limited data on [1] response variability to both of these anti-platelet drugs, [2] efficacy of combining two point-of-care tests (POCT) simultaneously and [3] how it predicts the clinical outcome after percutaneous coronary intervention (PCI).Methods: We analyzed 716 patients, enrolled in the CILON-T prospective randomized controlled trial, with both VerifyNow P2Y12 (PRU) and Aspirin (ARU) data at discharge. Patients were classified according to the tertile of PRU, ARU and the sum of the tertiles of PRU and ARU. The primary endpoint was the composite of cardiac death, nonfatal myocardial infarction (MI) and ischemic stroke at 6 months post-PCI.Results: Ten patients reached the primary endpoint, four of which were nonfatal MI and six ischemic stroke. When analyzed for the primary endpoint, tertiles of ARU and PRU were not able to discriminate patients with future thrombotic events from the remainder (<I>p</I>= 0.197 for ARU and 0.058 for PRU with the log-rank test, respectively), whereas combining the tertiles of ARU and PRU was significantly effective (<I>p</I>= 0.019 for ARU+PRU with the log-rank test). Multivariate analysis showed that the highest tertile of the sum of ARU and PRU tertiles was the only significant predictor of future thrombotic events after PCI (HR 6.34, 95% confidence interval 1.32-30.47, <I>p</I>= 0.021).Conclusions: In this post-hoc analysis of the CILON-T trial, combining the results of ARU and PRU simultaneously had a significant role in discriminating patients at highest risk of future thrombotic events after PCI compared with either assay alone.</P>
( Kang Pyo Kim ),( Nam Woo Kwon ),( Beom Kyung Kim ),( Seung Up Kim ),( Do Young Kim ),( Sang Hoon Ahn ),( Kwang Hyub Han ),( Chae Yoon Chon ),( Jun Yong Park ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1
Background: With wide use of vaccination and antiviral agents against hepatitis B virus (HBV) infection, epidemiologic characteristics of HBV-infected patients have changed substantially for several decades in South Korea, however, recent data are lacking. Hence, we reviewed the recent clinical characteristics of patients with chronic hepatitis B (CHB). Methods: From January 2010 to December 2010, we studied 5,262 consecutive HBV-infected patients who visited in Severance Hospital. Data concerning demographic profiles, laboratory findings about viral activity, and antiviral therapy were gathered. Results: Among the whole population, the median age was 51.0 and 66.0% were male. 1,788 (34.0%) had positive HBeAg and the median ALT level was 31.0 (2, 4700) IU/ml and 1,560 (29.6%) patients had family history of HBV-related liver disease. Regarding viral replication status, 297 (5%) patients were in immune tolerance phase, 2,195 (42%) in inactive phase, and the remaining 2,770 (53%) patients were in active CHB (eiher immune clearance or reactivation phase). Liver cirrhosis was diagnosed in 2,065 patients, among them, 611 (29.6%) patients had positive HBeAg, and 576 patients had experienced decompensation events including ascites, variceal bleeding, and hepatic encephalopathy. Hepatocellular carcinoma was diagnosed in 1,268 patients. Patients with HCC increased as they get older, especially after age of forty for male and after fifty for female. The male patients had a significantly higher ratio of the HCC than female patients did (78.7% vs. 21.3%, respectively, p<0.001). Conclusions: The study result shows that epidemiologic characteristics of CHB are male, elder, HBeAg negative dominant. The further studies are required to investigate the overall epidemiology of HBV infection in Korea.