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An Unusual Case of Delirium after Restarting Clozapine
Sourav Khanra,Rati Ranjan Sethy,Sanjay Kumar Munda,Christoday Raja Jayant Khess 대한정신약물학회 2016 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.14 No.1
Clozapine is a gold standard medication and drug of choice in refractory schizophrenia. Among many of its fatal side effects, delirium is less reported and inconsistently recognized by clinicians. We here present a case of delirium which emerged during retreatment with clozapine in a patient of paranoid schizophrenia. A patient diagnosed with paranoid schizophrenia, was restarted on clozapine after he left medications and became symptomatic. He was delirious on 22nd day after clozapine was restarted. Clozapine was stopped and the patient was managed with standard treatment for delirium. After one week interval, clozapine was restarted. Delirium was not noted till 6 weeks of his hospital stay. Clozapine induced central anticholinergic toxicity or clozapine induced seizure might cause delirium in index case. Limited literature exist delirium with clozapine. Clinicians must have high index of suspicion to detect delirium during clozapine therapy. More researches should focus to explore the association between delirium and clozapine.
Harianawala, Husain Hatim,Kheur, Mohit Gurunath,Apte, Sanjay Krishnaji,Kale, Bharat Bhanudas,Sethi, Tania Sanjeev,Kheur, Supriya Mohit The Korean Academy of Prosthodonitics 2014 The Journal of Advanced Prosthodontics Vol.6 No.6
PURPOSE. Translucency and colour stability are two most important aspects for an aesthetic dental restoration. Glass ceramic restorations are popular amongst clinicians because of their superior aesthetic properties. In the last decade, zirconia has generated tremendous interest due to its favorable mechanical and biological properties. However, zirconia lacks the translucency that lithium disilicate materials possess and therefore has limitations in its use, especially in esthetically demanding situations. There has been a great thrust in research towards developing translucent zirconia materials for dental restorations. The objective of the study was to evaluate and compare the transmittance of a translucent variant of zirconia to lithium disilicate. MATERIALS AND METHODS. Two commercially available zirconia materials (conventional and high translucency) and 2 lithium disilicate materials (conventional and high translucency) with standardized dimensions were fabricated. Transmittance values were measured for all samples followed by a microstructural analysis using a finite element scanning electron microscope. One way analysis of variance combined with a Tukey-post hoc test was used to analyze the data obtained (P=.05). RESULTS. High translucency lithium disilicate showed highest transmittance of all materials studied, followed by conventional lithium disilicate, high translucency zirconia and conventional zirconia. The difference between all groups of materials was statistically significant. The transmittance of the different materials correlated to their microstructure analysis. CONCLUSION. Despite manufacturers' efforts to make zirconia significantly more translucent, the transmittance values of these materials still do not match conventional lithium disilicate. More research is required on zirconia towards making the material more translucent for its potential use as esthetic monolithic restoration.
Bharat Bhanudas Kale,Tania Sanjeev Sethi,Supriya Mohit Kheur,Sanjay Krishnaji Apte,Mohit Gurunath Kheur,Husain Hatim Harianawala 대한치과보철학회 2014 The Journal of Advanced Prosthodontics Vol.6 No.6
PURPOSE Translucency and colour stability are two most important aspects for an aesthetic dental restoration. Glass ceramic restorations are popular amongst clinicians because of their superior aesthetic properties. In the last decade, zirconia has generated tremendous interest due to its favorable mechanical and biological properties. However, zirconia lacks the translucency that lithium disilicate materials possess and therefore has limitations in its use, especially in esthetically demanding situations. There has been a great thrust in research towards developing translucent zirconia materials for dental restorations. The objective of the study was to evaluate and compare the transmittance of a translucent variant of zirconia to lithium disilicate. MATERIALS AND METHODS Two commercially available zirconia materials (conventional and high translucency) and 2 lithium disilicate materials (conventional and high translucency) with standardized dimensions were fabricated. Transmittance values were measured for all samples followed by a microstructural analysis using a finite element scanning electron microscope. One way analysis of variance combined with a Tukey-post hoc test was used to analyze the data obtained (P=.05). RESULTS High translucency lithium disilicate showed highest transmittance of all materials studied, followed by conventional lithium disilicate, high translucency zirconia and conventional zirconia. The difference between all groups of materials was statistically significant. The transmittance of the different materials correlated to their microstructure analysis. CONCLUSION Despite manufacturers' efforts to make zirconia significantly more translucent, the transmittance values of these materials still do not match conventional lithium disilicate. More research is required on zirconia towards making the material more translucent for its potential use as esthetic monolithic restoration.
Rajpoot Sharad Chandra,Pandey Chanki,Rajpoot Prashant Singh,Singhai Sanjay Kumar,Sethy Prabira Kumar 대한전기학회 2021 Journal of Electrical Engineering & Technology Vol.16 No.4
This paper proposes a SUGPDS model based on Detection and Isolation algorithm and smart sensors, namely micro phasor measurement unit, smart sensing and switching device, phasor data concentrator, and ZigBee technology, etc. for the identifi cation, classifi cation, and isolation of the various fault occurs in the underground power cable in the distribution system. The proposed SUGPDS is a quick and smart tool in supervising, managing, and controlling various faults and issues and maintaining the reliability, stability, and uninterrupted fl ow of electricity. First, the SUGPDS model is analyzed using a distributed parameter approach. Then, the proper arrangement of the system required for the implantation of SUGPDS is demonstrated using fi gures. The Phasor data concentrator plays an essential role in developing the detection and classifi cation report for identifi cation and classifi cation. Finally, smart sensing and switching device installed at a diff erent location isolated the faulty phase from a healthy network. This approach helps to decrease power consumption. Hence, SUGPDS has super abilities compared to the underground power distribution system. The eff ectiveness of the proposed method and model is demonstrated via fi gures and tables