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Review : Barrett`s Esophagus: Diagnosis, Screening, Surveillance, and Controversies
( Rajvinder Singh ),( Krish Ragunath ),( Janusz Jankowski ) The Editorial Office of Gut and Liver 2007 Gut and Liver Vol.1 No.2
Barrett`s esophagus (BE) is a frequent complication of gastroesophageal reflux disease, an acquired condition resulting from persistent mucosal injury to the esophagus. The incidence of Barrett`s metaplasia and Barrett`s adenocarcinoma has been increasing, but the prognosis of Barrett`s adenocarcinoma is worse because individuals present at a late stage. Attempts have been made to intervene at early stage using surveillance programmes, although proof of efficacy of endoscopic surveillance is lacking. There is much to be learned about BE. Whether adequate control of gastroesophageal reflux early in the disease alters the natural history of Barrett`s change once it has developed remains unanswered. Thus there is great need for carefully designed large randomised controlled trials to address these issues in order to determine how best to manage patients with BE. The AspECT and BOSS clinical trials proride this basis. (Gut and Liver 2007;1:93-100)
Sam Costello,Rajvinder Singh 대한소화기내시경학회 2011 Clinical Endoscopy Vol.44 No.2
The practice for endoscopic surveillance of Barrett’s oesophagus has evolved from “blind” or random 4 quadrant biopsies (Seattle protocol) to a more “intelligent’’ targeted biopsy approach. This evolution has been possible due to the rapid advances in endoscopic imaging technology and expertise in the last decade. Previous endoscopes had relatively poor image resolution that often did not allow the subtle mucosal changes associated with dysplastic Barrett’s mucosa to be identified. Newer endoscopic imaging techniques available today may allow endoscopists to identify areas of dysplasia or malignancy and target biopsies accordingly. These modalities which include narrow band imaging, chromoendoscopy, autofluorescence imaging, and confocal endomicroscopy as well as a few novel imaging modalities on the horizon will be discussed further.
Current Status of Mucosal Imaging with Narrow-Band Imaging in the Esophagus
( Keng Hoong Chiam ),( Seon Ho Shin ),( Kun Cheong Choi ),( Florencia Leiria ),( Mariana Militz ),( Rajvinder Singh ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2021 Gut and Liver Vol.15 No.4
Recent advances in endoscopic imaging of the esophagus have revolutionized the diagnostic capability for detecting premalignant changes and early esophageal malignancy. In this article, we review the practical application of narrow-band imaging focusing on diseases of the esophagus, including Barrett’s esophagus, adenocarcinoma, and squamous cell carcinoma. (Gut Liver 2021;15:492-499)