LEGACY TRANSMISSION THROUGH FASHION FILMS: VISUAL AND NARRATIVE BRAND HERITAGE INTEGRATION.

Paloma Díaz-Soloaga,Gemma Muñoz Domínguez,Jing Zhou 글로벌지식마케팅경영학회 2021 Global Fashion Management Conference Vol.2021 No.11

Legacy transmission through fashion films: Visual and narrative brand heritage integration

Paloma Díaz Soloaga,Dominguez Gemma Muñoz,Zhou Jing 한국마케팅과학회 2023 Journal of Global Fashion Marketing Vol.14 No.4

On this research, we analyze how fashion houses transmit the spirit of the brands, convey the values that constitute their identity and show their heritage through fashion films. High end luxury brands with a long heritage such as Dior and Chanel, use audiovisual narratives fashion films, a form of visual and artistic communication, where the content establishes an emotional relationship between brand and customers and recreates the origins of the brand. Authors primarily selected, classified, and analyzed all fashion films that Chanel and Dior had published on YouTube, and then study a series of represen- tative samples selected from all those contents created by fashion brands. Based on the number of views, likes and comments of each video, it is possible to see the interaction between the brand and the audience and the engagement among the different fashion films. It also delves into the key of the brand to unearth the inheritance and tradition of its origin, trying to record the history of “Maison” to reach a wider audience and convey a series of values to new digital con- sumers. The combination of heritage and vitality through digital activities is oriented to deliver values that have a significant impact on the audience.

Allylpyrocatechol ameliorates sepsis-induced lung injury via SIRT1-mediated suppression of p65 and nucleocytoplasmic translocation of HMGB1

Mu Yanfei,Mu Xiaosong,Yang Yan,Zhou Yanhong 대한독성 유전단백체 학회 2021 Molecular & cellular toxicology Vol.17 No.4

Background Sepsis is a deadly clinical condition. Allylpyrocatechol is bioactive flavonoid that has shown promising anti-inflammatory and antioxidant activity. The effects of allylpyrocatechol on sepsis-induced lung injury have not been fully established. Objective This study investigated the effects of allylpyrocatechol in a mouse model of sepsis-induced lung injury. Results RAW264.7 macrophages were used for in vitro studies. A mouse model of sepsis was established by cecal ligation and puncture (CLP). The PaO2/FiO2 ratio was measured in conjunction with lung tissue histology, and edema was determined by the wet:dry tissue ratio. ELISA was performed to analyze levels of IL-6, TNF-α, NOx, and HMGB1. Malondialdehyde (MDA) levels were measured to determine lipid peroxidation status. Protein expression was investigated via Western blotting analyses. Molecular docking studies were done to study the affinity of SIRT1 with Allylpyrocatechol. It was observed that Allylpyrocatechol inhibited the production of HMGB1 and suppressed pro-inflammatory responses in macrophages treated with bacterial lipopolysaccharide (LPS) in vitro, and in CLP sepsis mice in vivo. Moreover, it ameliorated the reduction of SIRT1 levels in both LPS-treated macrophages and CLP mice, alleviated sepsis-induced lung edema, reduced lipid peroxidation, improved lung tissue histology findings, reduced mortality, and improved the PaO2/FiO2 ratio in CLP mice. Allylpyrocatechol caused significant reductions in serum levels of IL-6, nitric oxide, TNF-α, and HMGB1, as well as nuclear translocation of inducible nitric oxide synthase, SIRT1, and HMGB1 in lungs of CLP mice. Molecular docking analysis suggested affinity of SIRT1 with Allylpyrocatechol. Conclusion The findings suggest that Allylpyrocatechol protects mice against lung injury via SIRT1-mediated suppression of HMGB1 nuclear translocation and p-p65 activation. Background Sepsis is a deadly clinical condition. Allylpyrocatechol is bioactive flavonoid that has shown promising anti-inflammatory and antioxidant activity. The effects of allylpyrocatechol on sepsis-induced lung injury have not been fully established. Objective This study investigated the effects of allylpyrocatechol in a mouse model of sepsis-induced lung injury. Results RAW264.7 macrophages were used for in vitro studies. A mouse model of sepsis was established by cecal ligation and puncture (CLP). The PaO2/FiO2 ratio was measured in conjunction with lung tissue histology, and edema was determined by the wet:dry tissue ratio. ELISA was performed to analyze levels of IL-6, TNF-α, NOx, and HMGB1. Malondialdehyde (MDA) levels were measured to determine lipid peroxidation status. Protein expression was investigated via Western blotting analyses. Molecular docking studies were done to study the affinity of SIRT1 with Allylpyrocatechol. It was observed that Allylpyrocatechol inhibited the production of HMGB1 and suppressed pro-inflammatory responses in macrophages treated with bacterial lipopolysaccharide (LPS) in vitro, and in CLP sepsis mice in vivo. Moreover, it ameliorated the reduction of SIRT1 levels in both LPS-treated macrophages and CLP mice, alleviated sepsis-induced lung edema, reduced lipid peroxidation, improved lung tissue histology findings, reduced mortality, and improved the PaO2/FiO2 ratio in CLP mice. Allylpyrocatechol caused significant reductions in serum levels of IL-6, nitric oxide, TNF-α, and HMGB1, as well as nuclear translocation of inducible nitric oxide synthase, SIRT1, and HMGB1 in lungs of CLP mice. Molecular docking analysis suggested affinity of SIRT1 with Allylpyrocatechol. Conclusion The findings suggest that Allylpyrocatechol protects mice against lung injury via SIRT1-mediated suppression of HMGB1 nuclear translocation and p-p65 activation.

An R package UnifiedDoseFinding for continuous and ordinal outcomes in Phase I dose-finding trials

Rongji Mu,Chia Wei Hsu,Shouhao Zhou,Haitao Pan 한국통계학회 2022 Communications for statistical applications and me Vol.29 No.4

Phase I dose-finding trials are essential in drug development. By finding the maximum tolerated dose (MTD) of a new drug or treatment, a Phase I trial establishes the recommended doses for later-phase testing. The primary toxicity endpoint of interest is often a binary variable, which describes an event of a patient who experiences dose-limiting toxicity. However, there is a growing interest in dose-finding studies regarding non-binary outcomes, defined by either the weighted sum of rates of various toxicity grades or a continuous outcome. Although several novel methods have been proposed in the literature, accessible software is still lacking to implement these methods. This study introduces a newly developed R package, UnifiedDoseFinding, which implements three phase I dose-finding methods with non-binary outcomes (Quasi- and Robust Quasi-CRM designs by Yuan it et al. (2007) and Pan it et al. (2014), gBOIN design by Mu it et al.(2019), and by a method by Ivanova and Kim (2009)). For each of the methods, UnifiedDoseFinding provides corresponding functions that begin with next_ that determines the dose for the next cohort of patients, select\_, which selects the MTD defined by the non-binary toxicity endpoint when the trial is completed, and get_oc, which obtains the operating characteristics. Three real examples are provided to help practitioners use these methods. The R package UnifiedDoseFinding, which is accessible in R CRAN, provides a user-friendly tool to facilitate the implementation of innovative dose-finding studies with nonbinary outcomes.

New concept of half - palm mouse

( Zheng Mu Zhou ) 한국기초조형학회 2018 한국기초조형학회 작품집 Vol.2018 No.1

Efficient Anonymous Broadcast Encryption with Adaptive Security

( Fu-cai Zhou ),( Mu-qing Lin ),( Yang Zhou ),( Yu-xi Li ) 한국인터넷정보학회 2015 KSII Transactions on Internet and Information Syst Vol.9 No.11

Broadcast encryption is an efficient way to distribute confidential information to a set of receivers using broadcast channel. It allows the broadcaster to dynamically choose the receiver set during each encryption. However, most broadcast encryption schemes in the literature haven`t taken into consideration the receiver`s privacy protection, and the scanty privacy preserving solutions are often less efficient, which are not suitable for practical scenarios. In this paper, we propose an efficient dynamic anonymous broadcast encryption scheme that has the shortest ciphertext length. The scheme is constructed over the composite order bilinear groups, and adopts the Lagrange interpolation polynomial to hide the receivers` identities, which yields efficient decryption algorithm. Security proofs show that, the proposed scheme is both secure and anonymous under the threat of adaptive adversaries in standard model.

Insect-specific microRNA involved in the development of the silkworm Bombyx mori

Yong Zhang,Xue Zhou,Xie Ge,Jiang-Hao Jiang,Mu-Wang Li,Shi-Hai Jia,Xiao-Nan Yang,Yun-Chao Kan,Xue-Xia Miao,Guo-Ping Zhao,Fei Li,Yong-Ping Huang 한국응용곤충학회 2009 한국응용곤충학회 학술대회논문집 Vol.2009 No.10

MicroRNAs (miRNAs) are endogenous non-coding genes that participate in post-transcription regulation by either degrading mRNA or blocking its translation. It is considered to be very important in regulating insect development and metamorphosis. Insects are the largest group of animals and are extremely valuable in biological and agriculture research. Insects are also important pests to human health and agriculture, and efforts are necessary protect both humans and plants from disease and damage. Despite their importance, insects lag behind mammals, nematodes, and plants in miRNA research. At present, only 279 insect miRNAs have been identified from Drosophila melanogaster, Anopheles gambiae, Apis mellifera, Bombyx mori, and D. pseudoobscura in miRBase, and most of these miRNAs were computationally predicted without experimental validation. Functional analysis of insect miRNAs has only been conducted in D. melanogaster.

Rapid preparation and characterization of chitosan nanoparticles for oligonucleotide

Mu-hua Cheng,Yao-xiong Huang,Han-jian Zhou,Zhi Liu,Jian-fang Li 한국물리학회 2010 Current Applied Physics Vol.10 No.3

Chitosan is regarded as one of the potential candidates as a gene carrier. However, the poor solubility of chitosan is the major limiting factor in its utilization as a gene carrier. The purpose of this study was to simplify the method of preparing the nanoparticles of chitosan linked with antisense oligonucleotide (asON). The main step was preparing the derivatives of chitosan phosphate (CSP) in order to easily dissolve in aqueous solution. The nanoparticles were formed using a simple mixed method for CSP and asON, and the nanoparticle’s forming condition was optimized so that the nanoparticle’s characterization could be examined. Results showed that it was simple to make the nanoparticles under the optimal condition of 2:1 M proportion of CSP and asON. The size of the nanoparticles was 102.6 ± 12.0 nm, its zeta potential was 1.45 ± 1.75, and the encapsulated ratio of the chitosan crosslinked the asON was 87.6 ± 3.5%. The infrared spectra and electron microscope displayed that chitosan may combine with the asON to form equirotal nanoparticles. In conclusion, it was simple and feasible to form chitosan nanoparticles for asON using the CSP, and the CSP can efficiently encapsulate asON.

A Study on Multi-Objective Fuzzy Optimum Design of Truss Structures

Mu, Zai-Gen,Ge, Xin,Yan, Mou,Chen, Yun-Zhou 한국공간구조학회 2003 한국공간구조학회지 Vol.3 No.2

This paper presents decision making method of structural multi-objective fuzzy optimum problem. The data and behavior of many engineering systems are not know precisely and the designer is required to design the system in the presence of fuzziness in the multi-goals, constraints and consequences of possible actions. In this paper, in order to find a satisfactory solution, the membership functions are constructed for the fuzzy objectives subject to the fuzzy constraints, and two approaches are presented by using the different types of fuzzy decision making. Thus, multi-objective fuzzy optimum problem can be converted into single objective non-fuzzy optimum problem and satisfactory solution of the multi-objective fuzzy optimum problem can be found with general optimum programming. Illustrative numerical example of the ten bar truss for minimum weight and minimum deflection is provided to demonstrate the process of finding the solution and the results are discussed.

BLOW-UP FOR A NON-NEWTON POLYTROPIC FILTRATION SYSTEM WITH NONLINEAR NONLOCAL SOURCE

Zhou, Jun,Mu, Chunlai Korean Mathematical Society 2008 대한수학회논문집 Vol.23 No.4

This paper deals the global existence and blow-up properties of the following non-Newton polytropic filtration system, $${u_t}-{\triangle}_{m,p}u=u^{{\alpha}_1}\;{\int}_{\Omega}\;{\upsilon}^{{\beta}_1}\;(x,\;t)dx,\;{\upsilon}_t-{\triangle}_{n,p}{\upsilon}={\upsilon}^{{\alpha}_2}\;{\int}_{\Omega}\;u^{{\beta}_2}\;(x,{\;}t)dx,$$ with homogeneous Dirichlet boundary condition. Under appropriate hypotheses, we prove that the solution either exists globally or blows up in finite time depends on the initial data and the relations of the parameters in the system.