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Deformation Feature of Sheet Metals During Inclined Hole-Flanging by Two-Point Incremental Forming
Xia Chen,Tong Wen,Jian Qin,Jin Hu,Meng Zhang,Zhi-sun Zhang 한국정밀공학회 2020 International Journal of Precision Engineering and Vol.21 No.2
Incremental hole-flanging is an applicable extension of incremental sheet forming (ISF), but the knowledge on the deformation of metallic sheets during the course is lack, especially when the axes of the flanged necks are not perpendicular to the sheet plane. The current study used Al 6061 and SUS 304 stainless steel sheets with the thickness of 1 mm and 0.3 mm to examine the inclined hole-flanging processes on the flat plates by two-point ISF processes. It was found that, although as a whole the thickness variation is thinning, the decreasing degrees within upper and lower domain are not equal, and the difference increases with the inclination angle. Crack, buckling and local deformity are typical defects found in the experiments. The maximum springback increases with tool diameter, inclination angle and feeding pitch. Due to the material properties and a thinner thickness, local deformity is easier to take place on SUS 304 sheets during forming. Utilizing the tool feeding path along the oblique plane can obtain even force and consequently, more uniform deformation. Moreover, the equations for preliminarily determining the dimension of precut holes were derived according to the radial developed length of the flanged neck.
Creating Knowledge Graph of Electric Power Equipment Faults Based on BERT–BiLSTM–CRF Model
Meng Fanqi,Yang Shuaisong,Wang Jingdong,Xia Lei,Liu Han 대한전기학회 2022 Journal of Electrical Engineering & Technology Vol.17 No.4
Creating a large-scale knowledge graph of electric power equipment faults will facilitate the development of automatic fault diagnosis and intelligent question answering (QA) in the electric power industry. However, most existing methods have lower accuracy in Chinese entity recognition, thus it is hard to build such a high-quality knowledge graph by extracting knowledge from Chinese technical literature. To solve the problem, a novel model called BERT–BiLSTM–CRF is proposed. It blends Bi-directional Encoder Representation from Transformers (BERT), Bi-directional Long Short-Term Memory (BiLSTM), and Conditional Random Field (CRF). The model fi rstly identifi es and extracts electric power equipment entities from preprocessed Chinese technical literature. Then, the semantic relations between the entities are extracted based on the relation classifi cation method based on dependency parsing. Finally, the extracted knowledge is stored in the Neo4j database in the form of the triplet and visualized in the form of a graph. Through the above steps, a Chinese knowledge graph of electric power equipment faults can be built. The novelty of the model just lies in its subtle blend: the BERT module can not only learn phrase-level information representation, but also learn rich semantic information features; the CRF module realizes the constraint on the label prediction value and reduces the irregular recognition rate, so the accuracy rate of entity recognition is improved. Taking the Chinese technological literature, which is about fault diagnosis of electric power equipment as the experimental object, the experimental results show that the model identifi es and extracts Chinese entities more accurately than traditional methods. Thus, a comprehensive and accurate Chinese knowledge graph of electric power equipment faults could be constructed more easily.
Meng, Q.X.,Xia, Z.G.,Kerley, M.S. Asian Australasian Association of Animal Productio 2000 Animal Bioscience Vol.13 No.10
A continuous culture study was conducted to determine the impact of ruminal degradable soy protein (S-RDP) level and dilution rate (D) on growth of ruminal non-structural carbohydrate-fermenting microbes. Corn starch, urea and isolated soy protein (ISP) were used to formulate three diets with S-RDP levels of 0, 35 and 70% of total dietary CP. Two Ds were 0.03 and $0.06h^{-1}$ of the fermenter volume in a single-effluent continuous culture system. As S-RDP levels increased, digestibilities of dietary dry matter (DM), organic matter (OM) and crude protein (CP) linearly (p=0.001) decreased, whereas digestion of dietary starch linearly (p=0.001) increased. Increasing D from 0.03 to $0.06h^{-1}$ resulted in decreased digestibilities of dietary DM and OM, but had no effect on digestibilities of dietary starch (p=0.77) and CP (p=0.103). Fermenter pH, the concentration of volatile fatty acids (VFA) and daily VFA production were unaffected (p=0.159-0.517) by S-RDP levels. Molar percentages of acetate, propionate and butyrate were greatly affected by S-RDP levels (p=0.016-0.091), but unaffected by D (p=0.331-0.442). With increasing S-RDP levels and D, daily bacterial counts, daily microbial N production (DMNP) and microbial efficiency (MOEFF; grams of microbial N produced per kilogram of OM truly digested) were enhanced (p=0.001). The increased microbial efficiency with increasing S-RDP levels is probably the result of peptides or amino acids that served as a stimulus for optimal protein synthesis. The quantity of ruminal degradable protein from soy proteins required for optimum protein synthesis of non-structural carbohydrate-fermenting microbes appears to be equivalent to 9.5% of dietary fermented OM.
Effects of Allogeneic Blood Transfusion in Patients with Stage II Colon Cancer
Meng, Jin,Lu, Xiao-Bo,Tang, Yuan-Xin,Sun, Gong-Ping,Li, Xin,Yan, Yi-Fei,Liang, Gao-Feng,Ma, Si-Ping,Li, Xiao-Xia Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1
The aim of the present study was to determine whether allogeneic red blood cell transfusions showed a deleterious effect and what might be preoperative risk factors for blood transfusion in patients with TNM stage II colon cancer. Total 470 patients who fulfilled inclusion criteria were selected for a further 10-year follow-up study. We found that there were statistical significance between non-transfused and transfused group in mortality (P=0.018), local recurrence (P=0.000) and distant metastasis (P=0.040). Local recurrence and distant metastasis between 1 to 3 units and more than 3 units group did not show any significant differences. There was no difference in survival rate between non-transfused and 1 to 3 units group (log rank=0.031, P=0.860). The difference between different blood transfusion volume in transfused patients was found (78.77% vs 63.83%, P=0.006). Meanwhile, the significant difference of survival rate was existed between non-transfused group and more than 3 units group (84.83% vs 63.83%, P=0.002 ). Univariate analysis showed the following 3 variables to be associated with an increased risk of allogeneic blood transfusions: preoperative CEA level (P<0.05), location of tumor (P<0.01) and diameter of tumor (P<0.01). Multivariate analysis revealed that location of tumor and diameter of tumor are two independent factors for requirement of perioperative transfusions. Therefore, allogeneic transfusion increase the postoperative tumor mortality, local recurrence and distant metastasis in patients with stage II colon cancer. The postoperative tumor mortality, local recurrence and distant metastasis were not associated with the blood transfusion volume. The blood transfusion volume was associated with the survival rate. Location of tumor and diameter of tumor were the independent preoperative risk factors for blood transfusion.
Diaporthe taoicola and D. siamensis, Two New Records on Citrus sinensis in China
( Meng Jiao Cui ),( Xin Wei ),( Peng Liang Xia ),( Ji Ping Yi ),( Zhi He Yu ),( Jian Xin Deng ),( Qi Li Li ) 한국균학회 2021 Mycobiology Vol.49 No.3
Two Diaporthe species isolated from fruit of Citrus sinensis in China were characterized based on morphology and multilocus phylogeny of ITS, tef1, and tub2 gene sequences. The phylogeny indicated that the two species match Diaporthe taoicola and D. siamensis. A critical examination of phenotypic characteristics confirmed the phylogenetic results. Diaporthe taoicola was morphologically characterized by producing Alpha conidia with tapering toward both ends. Meanwhile, D. siamensis produced cylindrical or ellipsoidal Alpha conidia with two oil drops. Pathogenicity tests revealed that both species were pathogenic to fruit of C. sinensis. To our knowledge, the two species were firstly reported on Citrus sinensis in China.
Xia Qian,Zhan Gaofeng,Mao Meng,Zhao Yin,Li Xing 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-
Excessive and unresolved neuroinflammation is a key component of the pathological cascade in brain injuries such as ischemic stroke. Tripartite motif-containing 45 (TRIM45) is a ubiquitin E3 ligase involved in various critical biological processes. However, the role of TRIM45 in cerebral ischemia remains unknown. Here, we found that the TRIM45 protein was highly expressed in the peri-infarct areas of mice subjected to cerebral ischemia and reperfusion injury induced by middle cerebral artery occlusion. This study systemically evaluated the putative role of TRIM45 in the regulation of neuroinflammation during ischemic injury and the potential underlying mechanisms. We found that TRIM45 knockdown significantly decreased proinflammatory cytokine and chemokine production in primary cultured microglia challenged with oxygen-glucose deprivation and reoxygenation (OGD/R) treatment. Mechanistically, we demonstrated that TRIM45 constitutively interacted with TAB2 and consequently facilitated the Lys-63-linked polyubiquitination of TAB2, leading to the formation of the TAB1–TAK1–TAB2 complex and activation of TAK1, which was ultimately followed by activation of the nuclear factor-kappa B (NF-κB) signaling pathway. In an in vitro coculture Transwell system, downregulation of TRIM45 expression also inhibited the OGD/R-induced activation of microglia and alleviated neuronal apoptosis. More importantly, microglia-specific knockdown of TRIM45 in mice significantly reduced the infarct size, mitigated neurological deficit scores, and improved cognitive function after ischemic stroke. Taken together, our study reveals that the TRIM45–TAB2 axis is a crucial checkpoint that controls NF-κB signaling in microglia during cerebral ischemia and reperfusion injury. Therefore, targeting TRIM45 may be an attractive therapeutic strategy.