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수술적으로 치료한 통증을 동반한 흉추부의 후외상성 Schmorl씨 결절 : 2례 보고 Report of Two Cases
신병준,이재철,송화용,정석봉,권계원,조영일,김연일 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2
Study Design : Two patients who had painful Schmorl's node at thoracic level from acute trauma were adopted and taken operation for its treatment Objectives : To document the effect of operation for the treatment of painful Schmorl's node at thoracic level summary of background data : Schrmorl's nodes are common spinal lesion generally believed to be asymptomatic, but in some cases there were painful symptom by Schmorl's node. This case report is to explain the effect of operative treatment for the painful Schmorl's node. Methods : Two patients were adopted who had traumatic painful Schmorl's node at thoracic level for our case report. They were treated conservative methods at first but it's effect were poor, so they were taken anterior decompression and fusion, and checked back pain symptom. Result : In all two patients, the symptom of back pain by Schmorl's nodes at thoracic level was almost subsided. conclusion : For the treatment of traumatic painful Schmorl's node, most of surgeon says that conservative treatments were treatment of choice, but operative treatments are also benefit to subsidence of back pain by Schmorl's node.
Dong-Hwa Lee,Ju-Hee Lee,So Young Kim,Hae-Young Lee,Jung-Yeon Choi,Youjin Hong,Sue K. Park,Dong Ryeol Ryu,Dong Heon Yang,Seok-Jae Hwang,Jung Hyun Choi,Kye Hun Kim,Sun Hwa Lee,Seung Jae Joo,Jae-Hyeong P 대한내과학회 2022 The Korean Journal of Internal Medicine Vol.37 No.5
Background/Aims: The optimal systolic blood pressure (SBP) goal for elderly patients with hypertension, especially to reduce cardiovascular disease (CVD) incidence and improve outcome, is unclear. This study aimed to evaluate the beneficial effects of intensive treatment for hypertension on the incidence of CVD in elderly Korean patients. Methods: The HOW to Optimize eLDerly systolic Blood Pressure (HOWOLD-BP) trial is a multicenter, parallel-design, open-label, randomized controlled trial designed to evaluate whether intensive treatment (SBP ≤ 130 mmHg) will provide more benefits in lowering the incidence and mortality associated with CVD than standard treatment (SBP ≤ 140 mmHg) in elderly patients with hypertension aged ≥ 65 years. For this study, eleven university hospitals in Korea will enroll approximately 3,176 elderly patients with hypertension between 2019 and 2022. Patients will be requested to visit the clinic every 4 months for the first year and every 6 months thereafter for 36 months. Parameters, including clinic and home blood pressure, anthropometric and laboratory findings, and frailty assessments, will be collected according to the standardized protocol. The primary outcome is a composite of CVD (acute coronary syndrome, stroke, and heart failure) incidence and cardiovascular deaths. Results: As of December 2021, 1,655 participants had been enrolled in the study, including 831 patients in the standard group and 824 patients in the intensive group. Conclusions: The HOWOLD-BP trial is the first study performed in Korea to evaluate the beneficial effects of intensive blood pressure treatment on CVD in elderly patients with hypertension. The results of this study will help clarify the appropriate target SBP for this population.
SPECTRAL BEHAVIORS OF Hβ LINE OF CH CYGNI IN A QUIESCENT PHASE
KYE HWA YOO,KANG MIN KIM,BYUNG CHUL LEE,TAE SEOG YOON,JUNG AE LEE 한국천문학회 2004 天文學論叢 Vol.19 No.1
We analyzed the high resolution H,6 line spectra of CH Cygni obtained at the Bohyunsan Astronomical Observatory (BOAO) on April 2004. The temporal changes in the Hβ line profiles are reported. We obtained the equivalent widths of the Gaussian components. Using this we estimated the length of the gaseous nebula which emits the Hβ line and the mass loss rate from the star.
Lee, Kye Hwa,Lim, Jae Hyeun,Kim, Ju Han Korea Genome Organization 2013 Genomics & informatics Vol.11 No.1
In cancer genome studies, the annotation of newly detected oncogene/tumor suppressor gene candidates is a challenging process. We propose using concept lattice analysis for the annotation and interpretation of genes having candidate somatic mutations in whole-exome sequencing in acute myeloid leukemia (AML). We selected 45 highly mutated genes with whole-exome sequencing in 10 normal matched samples of the AML-M2 subtype. To evaluate these genes, we performed concept lattice analysis and annotated these genes with existing knowledge databases.
Lee, Kye Hwa,Kim, Grace Juyun,Kim, Ju Han The Korean Academy of Medical Sciences 2015 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.30 No.11
<P>The relationship between the number of withdrawn/restricted drugs and socioeconomic, health, and welfare indicators were investigated in a comprehensive review of drug regulation information in the United Nations (UN) countries. A total of of 362 drugs were withdrawn and 248 were restricted during 1950-2010, corresponding to rates of 12.02±13.07 and 5.77±8.69 (mean±SD), respectively, among 94 UN countries. A socioeconomic, health, and welfare analysis was performed for 33 OECD countries for which data were available regarding withdrawn/restricted drugs. The gross domestic product (GDP) per capita, GDP per hour worked, health expenditure per GDP, and elderly population rate were positively correlated with the numbers of withdrawn and restricted drugs (<I>P</I><0.05), while the out-of-pocket health expenditure payment rate was negatively correlated. The number of restricted drugs was also correlated with the rate of drug-related deaths (<I>P</I><0.05). The World Bank data cross-validated the findings of 33 OECD countries. The lists of withdrawn/restricted drugs showed markedly poor international agreement between them (Fleiss's kappa=-0.114). Twenty-seven drugs that had been withdrawn internationally by manufacturers are still available in some countries. The wide variation in the numbers of drug withdrawals and restrictions among countries indicates the need to improve drug surveillance systems and regulatory communication networks.</P>
Jieun Lee,HyoJin Kim,Yong Uk Kye,Dong Yeon Lee,Wol Soon Jo,Chang Geun Lee,Jeung Kee Kim,Jeong-Hwa Baek,Yeong-Rok Kang Korean Nuclear Society 2023 Nuclear Engineering and Technology Vol.55 No.7
The radioactivity concentration of environmental radionuclides was analyzed for soil and sand at eight locations within a radius of 255 m centered on the Dongnam Institute of Radiological & Medical Science (DIRAMS), Korea. The average activity concentrations of <sup>40</sup>K, <sup>137</sup>Cs, <sup>226</sup>Ra, and <sup>232</sup>Th were 661.1 Bq/kg-dry, 0.9 Bq/kg-dry, 21.9 Bq/kg-dry, and 11.1 Bq/kg-dry, respectively. The activity of <sup>40</sup>K and <sup>137</sup>Cs was lower than the 3-year (2017-2019) average reported by the Korea Institute of Nuclear Safety, respectively. Due to the nature of granite-rich soil, the radioactivity of <sup>40</sup>K was 0.6-fold higher than in other countries, while <sup>137</sup>Cs was in the normal fluctuation range (15-30 Bq/kg-dry) of the concentration of radioactive fallout from nuclear tests. The activity of <sup>226</sup>Ra and <sup>232</sup>Th was lower than in Korean soils reported by the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR). The average activity concentrations of <sup>232</sup>Th and <sup>40</sup>K for the soil and sand samples from DIRAMS were within the range specified by UNSCEAR in 2000. The radium equivalent activity and internal and external hazard index values were below the recommended limits (1 mSv/y). These radionuclide concentration (<sup>226</sup>Ra, <sup>232</sup>Th, <sup>40</sup>K, and <sup>137</sup>Cs) data can be used for regional environmental monitoring and ecological impact assessments of nuclear power plant accidents.