http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Psoriasis and Cardiovascular Disease: A Narrative Review
Adrian Martinez-Moreno,Jorge Ocampo-Candiani,Veronica Garza-Rodriguez 대한가정의학회 2021 Korean Journal of Family Medicine Vol.42 No.5
Psoriasis is a chronic, autoimmune, and inflammatory disease that affects 2% of the world’s population. In recent years, it has been demonstrated that psoriasis confers a 25% increase in relative risk of cardiovascular disease, independent of factors such as hyperlipidemia, smoking, and obesity. The objective of this review was to analyze and describe the association between psoriasis and cardiovascular disease. In this review, we describe the epidemiological association of psoriasis and cardiovascular disease, pathophysiology, mechanisms, and its association with the well-known cardiovascular risk calculators. In addition, we describe diagnostic tools, such as imaging techniques and novel biomarkers, that are useful in the evaluation of atherosclerotic cardiovascular disease. Finally, we present different systemic therapies that are used in patients with psoriasis and their effect on atherosclerotic cardiovascular disease. This article provides an overview of the current literature on psoriasis and cardiovascular risk, which can be useful for primary care physicians in their daily clinical practice.
In Vitro Susceptibility of Mycobacterium tuberculosis Clinical Isolates to Garenoxacin and DA-7867
Vera-Cabrera, Lucio,Castro-Garza, Jorge,Rendon, Adrian,Ocampo-Candiani, Jorge,Welsh, Oliverio,Choi, Sung Hak,Blackwood, Kym,Molina-Torres, Carmen American Society for Microbiology 2005 Antimicrobial agents and chemotherapy Vol.49 No.10
<B>ABSTRACT</B><P>The in vitro activities of DA-7867, a novel oxazolidinone, and garenoxacin (BMS-284756) were compared to those of linezolid in 67 susceptible and drug-resistant clinical isolates of <I>Mycobacterium tuberculosis</I>. DA-7867 was the most active drug with an MIC90 of 0.125 μg/ml, compared to the MIC90s of 4 μg/ml of garenoxacin and 2 μg/ml of linezolid.</P>
Vera-Cabrera, Lucio,Gonzalez, Eva,Rendon, Adrian,Ocampo-Candiani, Jorge,Welsh, Oliverio,Velazquez-Moreno, Victor M.,Hak Choi, Sung,Molina-Torres, Carmen American Society for Microbiology 2006 Antimicrobial agents and chemotherapy Vol.50 No.9
<B>ABSTRACT</B><P>The in vitro activities of DA-7157, a novel oxazolidinone, against clinical isolates of <I>Nocardia brasiliensis</I> and <I>Mycobacterium tuberculosis</I> were determined. Equal MIC50s and MIC90s (0.25 and 0.5 μg/ml, respectively) were found for susceptible and multidrug-resistant isolates of <I>M. tuberculosis</I>. The <I>N. brasiliensis</I> isolates showed an MIC90 of 1 μg/ml and an MIC50 of 1 μg/ml. The DA-7157 prodrug, DA-7218, exhibited similar MICs for <I>M. tuberculosis</I> but fivefold-higher MICs for <I>N. brasiliensis</I>.</P>