불확실한 수율을 고려한 LED 칩 재고 관리 정책

성진모(Jinmo Sung),정봉주(Bongju Jeong),노가연(Kayeon, Noh) 대한산업공학회 2011 대한산업공학회 춘계학술대회논문집 Vol.2011 No.5

The LED (Light-emitting Diode) manufacturing system is characterized with uncertain production rate in push-pull hybrid production environment where inventory policy in chip stock points plays a crucial role in achieving both efficiency and quick response. This study proposes an efficient inventory management policy for chip stocks in LED manufacturing system and validates it. Production rates of chip in LED manufacturing are uncertain because of uncertain quality. Based on key process factors determining the quality of LED chip, production rates are statistically estimated. The modified mathematical allocation model for chip stocks is developed with real constraints such as binning rates and technical limits. With our model, the rule based inventory management policy is proposed. Real case data are used for validating the proposed policy and its extension is also discussed.

불확실한 수율을 고려한 LED 칩 재고 관리 정책

성진모(Jinmo Sung),정봉주(Bongju Jeong),노가연(Kayeon, Noh) 한국경영과학회 2011 한국경영과학회 학술대회논문집 Vol.2011 No.5

The LED (Light-emitting Diode) manufacturing system is characterized with uncertain production rate in push-pull hybrid production environment where inventory policy in chip stock points plays a crucial role in achieving both efficiency and quick response. This study proposes an efficient inventory management policy for chip stocks in LED manufacturing system and validates it. Production rates of chip in LED manufacturing are uncertain because of uncertain quality. Based on key process factors determining the quality of LED chip, production rates are statistically estimated. The modified mathematical allocation model for chip stocks is developed with real constraints such as binning rates and technical limits. With our model, the rule based inventory management policy is proposed. Real case data are used for validating the proposed policy and its extension is also discussed.

급성 칼슘통로차단제 중독에서 고용량 인슐린/정상혈당치료의 효과: 체계적 고찰

양진모 ( Jinmo Yang ),고동률 ( Dong Ryul Ko ),공태영 ( Taeyoung Kong ),주영선 ( Young Seon Joo ),유제성 ( Je Sung You ),정성필 ( Sung Phil Chung ) 대한임상독성학회 2015 대한임상독성학회지 Vol.13 No.2

Purpose: The purpose of this study is to evaluate the effectiveness and the adverse events of high dose insulin/euglycemia therapy in acute calcium channel blocker (CCB) poisoning. Methods: We developed a systematic search strategy and applied it to 4 electronic reference databases. We searched medical journals as well as the bibliographies of relevant articles. All forms of literature relevant to human use of high dose insulin for acute CCB poisoning were included. The literature search was conducted by two investigators in August, 2015 with publication language restricted to English and Korean. Case reports were divided between CCB overdose alone and multi-drug overdose including CCB. The effect and adverse event of high dose insulin and clinical outcome of each case were analyzed. Results: Among 55 searched studies, 20 studies were included. A prospective study, a retrospective study, a systematic review study, and 17 case reports were identified. Case reports consisted of 11 CCB alone and 12 multidrug overdose cases including CCB. Although most cases described significant clinical improvements, one of them showed no beneficial effect. Several adverse events including hypoglycemia and hypokalemia were reported. No significant sequalae from adverse events was reported. Conclusion: Although there were many case reports demonstrating successful use of high dose insulin for CCB poisoning, the effect cannot be estimated due to a possibility of publication bias. Therefore, high dose insulin/euglycemia therapy might be considered adjunctive therapy in cases of CCB intoxication refractory for standard therapy.

Development of Browning Technology for Shiitake in Sawdust with LED

Jinmo Koo,Sung-Hak Lee,Seo-Wan Park,Hyo-Chan Park,Woo-Sik Jo 한국버섯학회 2017 버섯 Vol.21 No.2

Shiitake culture in sawdust is a widely applied method, which can supplement the disadvantages of costly and time consuming oak log cultivation. In sawdust cultivation, browning of surface mycelia is an important stage for the productivity and longevity of sawdust media. Surface browning forms protection coat for the substrate, which can block the invasion of outer pathogens and suppress water evaporation in the substrate. We controlled different light source (red LED, white LED, blue LED, and fluorescent light) with different intensity of illumination (1.5, 10.5, 20.5 μmol/m2s for LEDs and 10, 100, 300 lux for fluorescent light) to induce browning. Lights were treated with 1 hour on/ 1 hour off cycle maintained in a controlled room with 20oC temperature, 60% humidity, and 1200 ppm CO2 atmosphere concentration for 67 days. Browning effect differed from the source and intensity of illumination. Browning was most effective in 1.5 μmol/m2s for blue LED. All light sources showed less browning in highest intensity of illumination, which indicates that higher than 20.5 μmol/m2s for LEDs or 300 lux for fluorescent light are not effective. After harvesting fruit bodies, we measured their weight, length and width of pileus and stipe, chromaticity, and hardness. Treatment with 1.5 μmol/m2s blue LED produced the best harvest with highest average individual weight (21.2g), stipe length (30.8 mm), and hardness (377.9 g) with fine length and width of pileus, and chromaticity. This results indicate that 1.5 μmol/m2s blue LED showed the best browning effect which resulted in the best harvest yeild.

Browning technology for shiitake in sawdust using LED source

Jinmo Koo,Sang-Hwa Lee,Sung-Hak Lee,Woo-Ram Park,Jae Soon Hwang,Minkyeong Kim,Hyungseo Jun,Hee-Young Jung,Woo-Sik Jo 한국버섯학회 2018 한국버섯학회지 Vol.16 No.4

The incorporation of Shiitake culture into sawdust is a widely utilized technique that can assist in reducing the cost and time consumption associated with oak cultivation. In sawdust cultivation, browning of the surface mycelia is an important stage with respect to the utility and longevity of the sawdust media. Surface browning forms a protective coating on the substrate, which can inhibit the invasion of pathogens and suppress water evaporation. Several different light sources (red LED, white LED, blue LED, and fluorescent light) were used and the intensity of illumination was carefully controlled (1.5, 10.5, 20.5 μmol/m2s for LEDs and 10, 100, 300 lux for the fluorescent light) to induce browning. The light sources were regulated via a 1 h on/off cycle in a controlled room environment at a temperature of 20°C, 60% humidity, and 1200 ppm CO2 concentration for 60days.The browning effect varied depending on the source and the intensity of illumination. This effect was most effectively induced at 1.5 μmol/m2s for the red and blue LEDs. All light sources induced less browning at the highest intensity of illumination. This indicates that intensity values higher than 20.5 μmol/m2s in the case of the LEDs and 300 lux for the fluorescent light are not effective. After harvesting of the fruit bodies, we measured the weight, length, and width of the pileus and stipe in addition to their chromaticity and hardness. Treatment with 1.5 μmol/m2s blue LED produced the best harvest with the highest average chromaticity, weight (21.2 g), stipe length (30.8 mm), and hardness (377.9 g), with a fine length and width of the pileus.

Studies on the morphological characteristics of Wolfiporia cocos fruit bodies and basidiospores

Jinmo Koo,Sung-Hak Lee,Eun-Hee Kim,Woo-Sik Jo 한국버섯학회 2017 버섯 Vol.21 No.1

Wolfiporia cocos is a widely known traditional medicine in China, Japan, Korea, and other Asian countries due to its various medicinal effect. Aiming to determine the optimum condition for W. cocos fruit body induction, we cultured 10 strains of W. cocos on potato dextrose agar medium (PDA) in different temperature conditions (12, 16, 20, 24, 28oC). KFRI 1105 exceptively formed fuitbody in low temperatures (12 and 16oC), but in other strains, fruit body induction was restricted. in 12 and 16oC. Fruit body formation started 20oC, and formation rate increased proportionally with the temperature increase. 5 strains induced fruit body in 20oC, 7 strains in 24oC, and 9 strains in 28oC. This is the first research to identify a fruit body formation in vitro cultured W. cocos in Korea. This investigation will enable further studies of W. cocos physiology and breeding. In summary : 1. We identified the optimal conditions for W. cocos fruit body induction in the PDA plate. 2. The fruit body was best induced when it was cultured in 28 oC for 32 days. 3. The fruit bodies showed a honeycomb-like structure, and the average spore size was 7.55 μm in height and the average width was 3.35 μm.

Development of browning technology for Lentinus edodes in sawdust medium with LED

Jinmo Koo,Sung-Hak Lee,Eun-Hee Kim,Seo-Wan Park,Hyo-Chan Park,Woo-Sik Jo 한국버섯학회 2017 버섯 Vol.21 No.1

Shiitake culture in sawdust is a widely applied method, which can supplement the disadvantages of costly and time consuming oak log cultivation. In sawdust cultivation, browning of surface mycelia is an important stage for the productivity and longevity of sawdust media. Surface browning forms protection coat for the substrate, which can block the invasion of outer pathogens and suppress water evaporation in the substrate. We controlled different light source (red LED, white LED, blue LED, and fluorescent light) with different intensity of illumination (1.5, 10.5, 20.5 μmol/m2s for LEDs and 10, 100, 300 lux for fluorescent light) to induce browning. Lights were treated with 1 hour on/ 1 hour off cycle maintained in a controlled room with 20℃ temperature, 60% humidity, and 1200 ppm CO2 atmosphere concentration for 60 days. Browning effect differed from the source and intensity of illumination. Browning was most effective in 1.5 μmol/m2s for red and blue LED. All light sources showed less browning in highest intensity of illumination, which indicates that higher than 20.5 μmol/m2s for LEDs or 300 lux for fluorescent light are not effective. After harvesting fruit bodies, we measured their weight, length and width of pileus and stipe, chromaticity, and hardness. Treatment with 1.5 μmol/m2s blue LED produced the best harvest with highest average individual weight (21.2g), stipe length (30.8 mm), and hardness (377.9 g) with fine length and width of pileus, and chromaticity. This results indicate that 1.5 μmol/m2s blue LED showed the best browning effect which resulted in the best harvest yield.

Browning technology for shiitake in sawdust using LED source

Koo, Jinmo,Lee, Sang-Hwa,Lee, Sung-Hak,Park, Woo-Ram,Hwang, Jae Soon,Kim, Minkyeong,Jun, Hyungseo,Jung, Hee-Young,Jo, Woo-Sik The Korean Society of Mushroom Science 2018 한국버섯학회지 Vol.16 No.4

The incorporation of Shiitake culture into sawdust is a widely utilized technique that can assist in reducing the cost and time consumption associated with oak cultivation. In sawdust cultivation, browning of the surface mycelia is an important stage with respect to the utility and longevity of the sawdust media. Surface browning forms a protective coating on the substrate, which can inhibit the invasion of pathogens and suppress water evaporation. Several different light sources (red LED, white LED, blue LED, and fluorescent light) were used and the intensity of illumination was carefully controlled (1.5, 10.5, $20.5{\mu}mol/m^2s$ for LEDs and 10, 100, 300 lux for the fluorescent light) to induce browning. The light sources were regulated via a 1 h on/off cycle in a controlled room environment at a temperature of $20^{\circ}C$, 60% humidity, and 1200 ppm $CO_2$ concentration for 60days. The browning effect varied depending on the source and the intensity of illumination. This effect was most effectively induced at $1.5{\mu}mol/m^2s$ for the red and blue LEDs. All light sources induced less browning at the highest intensity of illumination. This indicates that intensity values higher than $20.5{\mu}mol/m^2s$ in the case of the LEDs and 300 lux for the fluorescent light are not effective. After harvesting of the fruit bodies, we measured the weight, length, and width of the pileus and stipe in addition to their chromaticity and hardness. Treatment with $1.5{\mu}mol/m^2s$ blue LED produced the best harvest with the highest average chromaticity, weight (21.2 g), stipe length (30.8 mm), and hardness (377.9 g), with a fine length and width of the pileus.

신이식 환자에서 마이코페놀레이트 병합을 통한 싸이클로스포린 감량요법의 전향적 연구결과

강진모(Jinmo Kang),박양진(Yang Jin Park),하종원(Jongwon Ha),이태승(Taeseung Lee),정중기(Jungkee Chung),김연수(Yon Su Kim),안규리(Curie Ahn),김상준(Sang Joon Kim) 대한외과학회 2008 Annals of Surgical Treatment and Research(ASRT) Vol.74 No.4

Purpose: Although cyclosporine (CsA) improves short-term renal graft outcomes, many paradigms reduce or withdraw this drug because of its nephrotoxicity. However, inadequate immunosuppression with azathioprine led to little success. We conducted a prospective study to define the prolonged effect of CsA reduction in stable renal transplant recipients with mycophenolate mofetil (MMF). Methods: Thirty-nine primary renal transplant recipients were divided into two cohorts, the AZA (N=13) and the MMF cohort (N=26). Both cohorts were allowed to reduce the CsA dose up to 50% of baseline within 3 to 4 months of conversion to AZA or MMF. Graft function, clinical parameters, and adverse events were monitored for up to 3 years. Results: Ccr gradually deteriorated in the AZA cohort, but was stable in the MMF cohort. There was no episode of acute rejection or graft loss observed in either cohort. Conclusion: The CsA dose can be reduced in combination with MMF treatment in stable renal transplant recipients after 2 years of transplantation, resulting in beneficial effects on Ccr, lipid profiles, and blood pressure.

당뇨병성 케톤산증의 회복 중에 발생한 Torsades de Pointes 유발 심정지 증례

김진모 ( Jinmo Kim ),이주엽 ( Ju Yeop Lee ),유원상 ( Won Sang Yoo ),이명용 ( Myung Yong Lee ),정현경 ( Hyun-kyung Chung ) 대한내과학회 2021 대한내과학회지 Vol.96 No.5

당뇨병성 케톤산증 환자는 QT 간격 연장, 그리고 이에 따른 Torsades de Pointes 발생 위험의 위험요소를 많이 내포하고 있으며 실제로 치명적인 부정맥인 Torsades de Pointes, 그리고 그에 따른 심정지를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Diabetic ketoacidosis (DKA) is an acute complication related to severe hyperglycemia. While the mortality rate for DKA is low with appropriate therapy, several complications may lead to deterioration of the clinical course. Here, we report a case of a 23-year-old patient with DKA who suffered from a rare but hemodynamically unstable cardiac arrhythmia, polymorphic ventricular tachycardia with prolonged QT interval, or Torsades de Pointes. During the recovery phase of DKA, three episodes of Torsades de Pointes suddenly occurred, and were recovered by immediate defibrillation. The patient did not have structural heart disease or a genetic predisposition. To the best of our knowledge, this is the first report of an adult with DKA complicated with QT prolongation related to Torsades de Points after correction of ketosis. To manage DKA, more attention may be needed on changes in the QT interval as well as risk factors for Torsades de Points. (Korean J Med 2021;96:432-437)