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Meichun Huang,Runzi Luo,Jiaojiao Fu,Haipeng Su 제어·로봇·시스템학회 2023 International Journal of Control, Automation, and Vol.21 No.5
The main goal of this article is to consider the synchronization of a class of chaotic systems with timevarying delay and external disturbances. A new control method, which is the impulsive intermittent control strategy, is proposed. In our control scheme, the time interval between impulsive control and intermittent control is variable. In addition, the “working time” interval and the “rest time” interval of intermittent control are also changeable. By designing an impulsive intermittent controller, a new asymptotic stability theorem is obtained to ensure the asymptotic synchronization of a class of time-varying delay chaotic systems with variable external disturbances. Numerical simulations are given to demonstrate the applicability and validity of the proposed scheme.
Lijun Tang,Jiaojiao Guo,Zhenlong Huang 대한화학회 2013 Bulletin of the Korean Chemical Society Vol.34 No.4
A known Hg2+ selective rhodamine B derivatised probe 1 was reinvestigated as a colorimetric and fluorescent probe for Cu2+ through changing the applied solvent media. Probe 1 exhibited good selectivity and sensitivity to Cu2+ in CH3CN-H2O (7:3, v/v, HEPES 10 mM, pH 7.0) solution with a detection limit of 9.74 × 10−7 M. The Cu2+ sensing event was proved to be irreversible through hydrolysis of 1 to release rhodamine B.
Tang, Lijun,Guo, Jiaojiao,Huang, Zhenlong Korean Chemical Society 2013 Bulletin of the Korean Chemical Society Vol.34 No.4
A known $Hg^{2+}$ selective rhodamine B derivatised probe 1 was reinvestigated as a colorimetric and fluorescent probe for $Cu^{2+}$ through changing the applied solvent media. Probe 1 exhibited good selectivity and sensitivity to $Cu^{2+}$ in $CH_3CN-H_2O$ (7:3, v/v, HEPES 10 mM, pH 7.0) solution with a detection limit of $9.74{\times}10^{-7}$ M. The $Cu^{2+}$ sensing event was proved to be irreversible through hydrolysis of 1 to release rhodamine B.
Robust Fixed Time Control of a Class of Chaotic Systems with Bounded Uncertainties and Disturbances
Haipeng Su,Runzi Luo,Meichun Huang,Jiaojiao Fu 제어·로봇·시스템학회 2022 International Journal of Control, Automation, and Vol.20 No.3
This paper investigates the fixed time control of a class of chaotic systems with uncertainties and disturbances via a novel fixed time theorem. By using variable substitution to calculate definite integral, a sufficient condition for fixed-time stability is firstly derived. Then, based on the given fixed time stable theory, a new nonlinear slide mode surface is proposed. By using a novel robust controller, the system’s state trajectories are driven to its origin in a fixed time which is independent on the initial value. The control strategy is applied to the permanent magnet synchronous motor (PMSM) chaotic system, and the results of numerical simulation demonstrate the effectiveness of the proposed schemes.
( Mulan Wei ),( Xujie Liu ),( Chunyu Cao ),( Jianlin Yang ),( Yafeng Lv ),( Jiaojiao Huang ),( Yanlin Wang ),( Ye Qin ) 생화학분자생물학회(구 한국생화학분자생물학회) 2018 BMB Reports Vol.51 No.11
Recent studies showed that the PD-1/PD-L1 checkpoint blockade is a dramatic therapy for melanoma by enhancing antitumor immune activity. Currently, major strategies for the PD-1/PD-L1 blockade have mainly focused on the use of antibodies and compounds. Seeking an alternative approach, others employ endogenous proteins as blocking agents. The extracellular domain of PD-1 (ePD1) includes the binding site with PD-L1. Accordingly, we constructed a PD-1-based recombinantly tailored fusion protein (dFv-ePD1) that consists of bivalent variable fragments (dFv) of an MMP-2/9-targeted antibody and ePD1. The melanoma-binding intensity and antitumor activity were also investigated. We found the intense and selective binding capability of the protein dFv-ePD1 to human melanoma specimens was confirmed by a tissue microarray. In addition, dFv-ePD1 significantly suppressed the migration and invasion of mouse melanoma B16-F1 cells, and displayed cytotoxicity to cancer cells in vitro. Notably, dFv-ePD1 significantly inhibited the growth of mouse melanoma B16-F1 tumor cells in mice and in vivo fluorescence imaging showed that dFv-ePD was gradually accumulated into the B16-F1 tumor. Also the B16-F1 tumor fluorescence intensity at the tumor site was stronger than that of dFv. This study indicates that the recombinant protein dFv-ePD1 has an intensive melanoma-binding capability and exerts potent therapeutic efficacy against melanoma. The novel format of the PD-L1-blocked agent may play an active role in antitumor immunotherapy. [BMB Reports 2018; 51(11): 572-577]