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Jia, Yao,Hu, Ting,Hang, Chuan-Ying,Yang, Ru,Li, Xiong,Chen, Zhi-Lan,Mei, Ye-Dong,Zhang, Qing-Hua,Huang, Ke-Cheng,Xiang, Qun-Ying,Pan, Xiu-Yu,Yan, Yu-Ting,Wang, Xiao-Li,Wang, Shao-Shuai,Hang, Zhou,Tang Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.10
Purpose: To investigate the diet of patients with cervical cancer and precancerosis in the Wufeng area, a high-incidence region in China. Methods: In the case group, 104 patients diagnosed with cervical cancer or cervical intraepithelial neoplasias (CINII/III) were recruited from the Wufeng area. Nine hundred thirty-six healthy women were selected from the same area as the matched controls. A questionnaire, which included questions about general lifestyle conditions, smoking and alcohol status, source of drinking water, green tea intake, and diet in the past year, was presented to all participants. Results: Green tea intake (P=0.022, OR=0.551, 95% CI=0.330-0.919) and vegetable intake (P=0.035, OR=0.896, 95% CI=0.809-0.993) were identified as protective factors against cervical cancer or CINII/III. There was no indication of any associations of other lifestyle factors (smoking status, alcohol status, source of drinking water) or diet (intake of fruit, meat/egg/milk, soybean food, onion/garlic, staple food and pickled food) with cervical cancer. Conclusions: The results suggest that eating more fresh vegetables and drinking more green tea may help to reduce the risk of cervical cancer or CINII/III in people of the Wufeng area.
Dual-Mode Liquid Crystal Devices with Switchable Memory and Dynamic Modes
Yao, I-An,Kou, Hsiao-Ti,Yang, Chiu-Lien,Liao, Shih-Fu,Li, Jia-Hsin,Wu, Jin-Jei The Korean Infomation Display Society 2009 Journal of information display Vol.10 No.4
A liquid crystal device with switchable dynamic and memory modes was investigated and developed. The proposed device reveals the splay, $\pi$-twist, and bend states via selective switching among them. In the dynamic mode, the device is operated in the bend state, which exhibits a wide viewing-angle and a fast-response-time due to its self-compensated bend structure and flow-accelerated fast response time, respectively. In the memory mode, the permanent memory characteristics in the splay and $\pi$-twist sates are obtained, respectively. The switching mechanisms of the tristate device are also proposed.
Jia-Piao Lin,Chao-Qin Chen,Ling-Er Huang,Na-na Li,Yan Yang,Sheng-Mei Zhu,Yong-Xing Yao 한국뇌신경과학회 2018 Experimental Neurobiology Vol.27 No.4
α2-Adrenoceptor agonists attenuate hypersensitivity under neuropathic conditions. However, the mechanisms underlying this attenuation remain largely unknown. In the present study, we explored the potential roles of purinergic receptor 7 (P2X7R)/extracellular signal-regulated kinase (ERK) signaling in the anti-nociceptive effect of dexmedetomidine in a rat model of neuropathic pain induced by chronic constriction injury (CCI) of the sciatic nerve. An animal model of CCI was adopted to mimic the clinical neuropathic pain state. Behavioral hypersensitivity to mechanical and thermal stimuli was determined by von Frey filament and Hargreaves’ tests, and the spinal P2X7R expression level and ERK phosphorylation were analyzed using western blot analysis and immunohistochemistry. In parallel with the development of mechanical and thermal hyperalgesia, a significant increase in P2X7R expression was noted in the ipsilateral spinal cord on day 7 after CCI. Intrathecal administration of dexmedetomidine (2.5 μg) for 3 days not only attenuated neuropathic pain but also inhibited the CCI-induced P2X7R upregulation and ERK phosphorylation. Intrathecal dexmedetomidine administration did not produce obvious effects on locomotor function. The present study demonstrated that dexmedetomidine attenuates the neuropathic pain induced by CCI of the sciatic nerve in rats by inhibiting spinal P2X7R expression and ERK phosphorylation, indicating the potential therapeutic implications of dexmedetomidine administration for the treatment of neuropathic pain.
Yang, Zhi-Ping,Xie, Yong-Hong,Ling, Dan-Yan,Li, Jin-Rui,Jiang, Jin,Fan, Yao-Hua,Zheng, Jia-Lian,Wu, Wan-Xin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.17
SCY1-like 1-binding protein 1 (SCYL1BP1) is a newly identified transcriptional activator domain containing protein with many unknown biological functions. Recently emerging evidence has revealed that it is a novel regulator of the p53 pathway, which is very important for the development of human cancer. However, the effects of SCYL1BP1 on human lung squamous carcinoma cell biological behavior remain poorly understood. In this study, we present evidence that SCYL1BP1 can promote the degradation of MDM2 protein and further inhibit the G1/S transition of lung squamous carcinoma cell lines. Functional assays found that reintroduction of SCYL1BP1 into lung squamous carcinoma cell lines significantly inhibited cell proliferation, migration, invasion and tumor formation in nude mice, suggesting strong tumor suppressive function of SCYL1BP1 in lung squamous carcinoma. Taken together, our data suggest that the interaction of SCYL1BP1/MDM2 could accelerate MDM2 degradation, and may function as an important tumor suppressor in lung squamous carcinomas.
Yang, Yankang,Qiu, Beibei,Chen, Shanshan,Zhou, Qiuju,Peng, Ying,Zhang, Zhi-Guo,Yao, Jia,Luo, Zhenghui,Chen, Xiaofeng,Xue, Lingwei,Feng, Liuliu,Yang, Changduk,Li, Yongfang The Royal Society of Chemistry 2018 Journal of materials chemistry. A, Materials for e Vol.6 No.20
<P>Solution-processed organic solar cells (OSCs) have been attracting more and more attention for a series of well-known advantages, and power conversion efficiencies (PCEs) of over 11% have been reported. However, the highest PCE of the OSCs based on small molecule donor/polymer acceptor blends is only 4.82%, which was much lower than those of other types of OSCs due to weak absorption of the polymer acceptor and the unbalanced charge carrier mobility of the small molecule donor and the polymer acceptor. Here, we fabricated small molecule donor/polymer acceptor-based OSCs using the wide bandgap SM1 and DR3TBDTT as the small molecular donor and the low-bandgap n-type conjugated polymer PZ1 as the polymer acceptor. With the treatment of a solvent additive, which can promote the absorption intensity, enhance the carrier mobility and suppress the charge carrier recombination, the SM1-based devices and the DR3TBDTT-based devices show PCEs of 3.97% and 5.86%, respectively. It is worth mentioning that the PCE of 5.86% is the state-of-the-art efficiency for OSCs based on the small molecular donor/polymer acceptor system.</P>
DAB Converter Based on Unified High-Frequency Bipolar Buck-Boost Theory for Low Current Stress
Jia-rong Kan,Yao-dong Yang,Yu Tang,Dong-chun Wu,Yun-ya Wu,Jiang Wu 전력전자학회 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.2
This paper proposes a unified high-frequency bipolar buck-boost (UHFBB) control strategy for a dual-active-bridge (DAB), which is derived from the classical buck and boost DC/DC converter. It can achieve optimized current stress of the switches and soft switching in wider range. The UHFBB control strategy includes multi-control-variables, which can be achieved according to an algorithm derived from an accurate mathematical model. The design method for the parameters, such as the transformer turns ratio and the inductance, are shown. The current stress of the switches is analyzed for selecting an optimal inductor. The analysis is verified by the experimental results within a 500W prototype.
Yang Fei,Shi Yu Jia,Lin Lin,Chen Jing Yao,Hou Meng Zhe,Yu Ke Xin,Zhang Yi Han,Yuan Zheng,Li Xiao Fang,Hu Yan Chun,Shang Jun,Yin Shao Qian,Wang Xian Wei 한국물리학회 2023 Current Applied Physics Vol.50 No.-
In this work, to prepare the PbZr0.52Ti0.48O3(PZT)/PbZrO3(PZ) multilayer films, PZ films and PZT films were spin-coated on LaNiO3/SiO2/Si substrates in sequence by the sol-gel method, and the PZ films were prepared using PZ precursor solution with different concentrations. After each spin-coating, PZ layer and PZT layer were annealed with rapid thermal annealing (RTA) technique at 650 ◦C and 550 ◦C, respectively. The crystal structures, microstructures and electrical properties of the films with different PZ film thickness were comprehensively investigated. The PZ films with different thickness showed perovskite phase. The PZT films on crystallized PZ films exhibited the coexistence of pyrochlore phase and perovskite phase at the annealing temperature of 550 ◦C. The PZT/PZ multilayer films with 0.2 M PZ precursor solution exhibit typical anti-ferroelectricity with double hysteresis loops, while other multilayer films exhibit nearly linear loops. In addition, the recoverable energy storage density increases with the increase of the film thickness and reaches the maximum value 32.4 J/ cm3 in the PZT/PZ multilayer films with 0.4 M PZ precursor solution. Therefore, the ferroelectric properties of the PZT/PZ multilayer films could be regulated by different PZ film thickness, which effectively further enhances the energy storage performance.
Tribological Properties of PAO40@SiO2/UHMWPE Composites Subjected to Heavy-loading Conditions
Yao Chenyu,Jia Dan,Wan Changxin,Li Jian,Zhan Shengpeng,Yang Tian,Qi Xiaowen,Liu Changxin,Duan Haitao 한국고분자학회 2022 폴리머 Vol.46 No.5
In the present study, the ballistic impact resistance of kevlar reinforced polymer composites and shape memoryalloy sheet reinforced kevlar epoxy polymer composites have been compared numerically and experimentally. The testspecimens have been fabricated by the hand layup method, and the ballistic impact test has been conducted accordingto NIJ Level IIIA. In the current research, a new method has been proposed to measure the ballistic impact resistanceof the material by using Image J software. From the test results, it has been observed that reinforcement of shape memoryalloy in kevlar epoxy polymer composites has increased the ballistic impact resistance by 89-145% for the damaged areacompared with plain kevlar reinforced epoxy polymer composite. Also, the damaged area observed in the numerical andthe experimental results is almost the same.
Effects of V2O5 on sinterability and microwave dielectric properties of NaCa4V5O17 ceramics
Guoguang Yao,Yang Li,Jingjing Tan,Cuijin Pei,Yan Zhang,Jia Chen 한양대학교 세라믹연구소 2020 Journal of Ceramic Processing Research Vol.21 No.3
The NaCa4V5O17 ceramics owing low sintering temperature had been prepared via conventional solid state reaction methodusing V2O5 as vanadium source. The sinterability, microwave dielectric characterisations and compatibility with Ag wereinvestigated. Pure phase NaCa4V5O17 with triclinic structure was confirmed by Rietveld refinement and Raman spectrum. Thepermittivity (εr) and quality factor (Qxf) values mainly depended on the relative density, whereas the temperature coefficientof resonant frequency (τf) value was closely connected with the tetrahedral distortion of V(1)O4. The NaCa4V5O17 ceramicssintered at 800 oС owned high densification and moderate microwave dielectric performances under 10.7 GHz: εr = 9.5, Q×f= 34,200 GHz, τf = -90.0 ppm/oС, but poor chemical compatibility with Ag paste.