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      • 저온에서 혐기성 소화에 대한 온도영향

        閔庚碩,金弘泰,姜玉熙 慶北大學校 1991 論文集 Vol.51 No.-

        This study was conducted to show the possibility of application of anaerobic digestion process in low temperature. Laboratory single-stage anaerobic digester was operated at 15 to 80 days' HRT at the temperature of 15℃, 20℃, 25℃ and 35℃. The results of this study indicated that the organic removal efficiencies and gas productions were remarkably decreased in low temperature. Despite of the low organic loading of 0.67 ㎏-COD/㎥·day at 15℃ the gas production was very poor as 0.16㎥CH_4/㎏COD removed. The observed maximum F/Mv ratio which would get the organic removal efficiencies of 70% and 60% respectively at the temperature of 20℃ and 15℃ were 0.1 ㎏COD/㎏MLVS·day. The substrate removal rates(Km) had a tendency to become larger at higher temperature, and were critical at the temperature of 20 to 25℃.

      • Research on Timing Synchronization Algorithm for Optical Signal Receiving

        Hong-min Wang,Zhong-jie Wang,Ping Xue 보안공학연구지원센터 2016 International Journal of Future Generation Communi Vol.9 No.4

        In consideration of the characteristics of visible light communication (VLC) and orthogonal frequency division multiplexing (OFDM) signal modulation mode, this paper presents some improvements from two aspects of timing metric function and training sequence structure on the basis of the traditional algorithms. In order to solve the problem of the correlation peak plateau and achieve the symbol accurate positioning, the power of the improved algorithm is normalized on the principle of maximum sliding auto-correlation (SAC). The simulation results show that the improved algorithm can obtain a more excellent timing synchronization performance and a lower symbol error rate (SER) in both the additive white Gaussian noise (AWGN) channel and the multipath frequency selective fading (MFSF) channel. Especially under the environment of a low signal noise ratio (SNR), the improved algorithm has overwhelming advantages over other three traditional algorithms.

      • DNA Microarray Probe Preparation by Gel Isolation Nested PCR

        Wang, Hong-Min,Ma, Wen-li,Huang, Hai,Xiao, Wei-Wei,Wang, Yan,Zheng, Wen-Ling Korean Society for Biochemistry and Molecular Biol 2004 Journal of biochemistry and molecular biology Vol.37 No.3

        To develop a simplified method that can rapidly prepare DNA microarray probes in a massive scale, a lambda phage genomic DNA-fragments library was constructed for the microarray-probes collection. Four methods of DNA band recovery from the first PCR products were tested and compared. The DNA microarray probes were collected by a novel method of nested PCR that was mediated by gel isolation of the first PCR products. This method was named GIN-PCR. The probes that were prepared by this GIN-PCR technique were used as subjects to fabricate a DNA microarray. The results showed that a wooden toothpick was superior to the other 3 methods, since this technique can steadily transfer the DNA bands as the template of the second PCR after the first PCR. A group of probes were successfully collected and DNA microarrays were constructed using these probes. Hybridization results demonstrated that this technique of DNA recovery and probe preparation was rapid, efficient, and effective. We developed a cost-effective and less labor-intensive method for DNA microarray probe preparation by nested PCR that is mediated by wooden toothpick transfer of the DNA bands in the gel after electrophoresis.

      • SCIESCOPUSKCI등재

        DNA Microarray Probe Preparation by Gel Isolation Nested PCR

        ( Hong Min Wang ),( Wen Li Ma ),( Hai Huang ),( Wei Wei Xiao ),( Yan Wang ),( Wen Ling Zheng ) 생화학분자생물학회 2004 BMB Reports Vol.37 No.3

        To develop a simplified method that can rapidly prepare DNA microarray probes in a massive scale, a lambda phage genomic DNA-fragments library was constructed for the microarray-probes collection. Four methods of DNA band recovery from the first PCR products were tested and compared. The DNA microarray probes were collected by a novel method of nested PCR that was mediated by gel isolation of the first PCR products. This method was named GIN-PCR. The probes that were prepared by this GIN-PCR technique were used as subjects to fabricate a DNA microarray. The results showed that a wooden toothpick was superior to the other 3 methods, since this technique can steadily transfer the DNA bands as the template of the second PCR after the first PCR. A group of probes were successfully collected and DNA microarrays were constructed using these probes. Hybridization results demonstrated that this technique of DNA recovery and probe preparation was rapid, efficient, and effective. We developed a cost-effective and less labor-intensive method for DNA microarray probe preparation by nested PCR that is mediated by wooden toothpick transfer of the DNA bands in the gel after electrophoresis.

      • Light Fades and Life Prediction of LED Light Source

        Hong-min Wang,Jin-shan Yao,Pin Xue 보안공학연구지원센터 2015 International Journal of Smart Home Vol.9 No.11

        The life is the most representative parameter in the parameters of LED reliability. But the impact factor of the LED lifetime are numerous and complicated, each factor of the influence degree of each are not identical. If according to the traditional light source life test method, then the cycle is too long to not led update speed. And the majority of the LED accelerated life test by means of increasing the should force experiments to estimate the life of the LED light source, this kind of test is usually elevated led where the ambient temperature or increasing the current through the LED itself. Finally, through the acquisition of data and analysis to predict the service life of LED light source, but did not direct theoretical foundation to justify force and the service life of LED light source specific equivalent relation. Therefore, the accuracy of accelerated stress measured the service life of LED light source is yet to be verified. Through the analysis of the change of the life of LED is a gradient of chemical reaction, with the Arrhenius model, led the life of the weakening is through changes in the flux to the lumen, and for that we can under the normal working condition analysis of LED light attenuation mechanism and rules, the prediction from but realize life led to predict led by degradation of cause and the change of life.

      • KCI등재

        Dissecting Causal Relationships Between Gut Microbiota, Blood Metabolites, and Stroke: A Mendelian Randomization Study

        Wang Qi,Dai Huajie,Hou Tianzhichao,Hou Yanan,Wang Tiange,Lin Hong,Zhao Zhiyun,Li Mian,Zheng Ruizhi,Wang Shuangyuan,Lu Jieli,Xu Yu,Liu Ruixin,Ning Guang,Wang Weiqing,Bi Yufang,Zheng Jie,Xu Min 대한뇌졸중학회 2023 Journal of stroke Vol.25 No.3

        Background and Purpose We investigated the causal relationships between the gut microbiota (GM), stroke, and potential metabolite mediators using Mendelian randomization (MR). Methods We leveraged the summary statistics of GM (n=18,340 in the MiBioGen consortium), blood metabolites (n=115,078 in the UK Biobank), and stroke (cases n=60,176 and controls n=1,310,725 in the Global Biobank Meta-Analysis Initiative) from the largest genome-wide association studies to date. We performed bidirectional MR analyses to explore the causal relationships between the GM and stroke, and two mediation analyses, two-step MR and multivariable MR, to discover potential mediating metabolites. Results Ten taxa were causally associated with stroke, and stroke led to changes in 27 taxa. In the two-step MR, <i>Bifidobacteriales</i> order, <i>Bifidobacteriaceae</i> family, <i>Desulfovibrio</i> genus, apolipoprotein A1 (ApoA1), phospholipids in high-density lipoprotein (HDL_PL), and the ratio of apolipoprotein B to ApoA1 (ApoB/ApoA1) were causally associated with stroke (all <i>P</i><0.044). The causal associations between <i>Bifidobacteriales</i> order, <i>Bifidobacteriaceae</i> family and stroke were validated using the weighted median method in an independent cohort. The three GM taxa were all positively associated with ApoA1 and HDL_PL, whereas <i>Desulfovibrio</i> genus was negatively associated with ApoB/ApoA1 (all <i>P</i><0.010). Additionally, the causal associations between the three GM taxa and ApoA1 remained significant after correcting for the false discovery rate (all q-values <0.027). Multivariable MR showed that the associations between <i>Bifidobacteriales</i> order, <i>Bifidobacteriaceae</i> family and stroke were mediated by ApoA1 and HDL_PL, each accounting for 6.5% (<i>P</i>=0.028) and 4.6% (<i>P</i>=0.033); the association between <i>Desulfovibrio</i> genus and stroke was mediated by ApoA1, HDL_PL, and ApoB/ApoA1, with mediated proportions of 7.6% (<i>P</i>=0.019), 4.2% (<i>P</i>=0.035), and 9.1% (<i>P</i>=0.013), respectively. Conclusion The current MR study provides evidence supporting the causal relationships between several specific GM taxa and stroke and potential mediating metabolites.

      • SCIESCOPUSKCI등재

        The Efficacy and Safety of Clonazepam in Patients with Anxiety Disorder Taking Newer Antidepressants: A Multicenter Naturalistic Study

        Sheng-Min Wang,Jung-Bum Kim,Jeong Kyu Sakong,Ho-Suk Suh,Kang Seob Oh,Jong-Min Woo,Sang-Woo Yoo,Sang Min Lee,Sang-Yeol Lee,Se-Won Lim,Seong Jin Cho,Ik-Seung Chee,Jeong-Ho Chae,Jin Pyo Hong,Kyoung-Uk Le 대한정신약물학회 2016 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.14 No.2

        Objective: This study compared the efficacy and tolerability of clonazepam with other benzodiazepines in patients with anxiety disorders. Methods: Inclusion criteria were as follows: age >20 years, diagnosis of anxiety disorder according to the Diagnostic and Statistical Manual of Mental Disorders 4th edition, text revision (DSM-IV-TR) criteria, taking only one type of antidepressant, and prescribed one of three oral benzodiazepines (alprazolam, clonazepam, or lorazepam). At baseline and week 6, clinical benefit was evaluated using the Clinical Global Impression-Severity Scale (CGI-S), Clinical Global Impression-Anxiety Scale (CGI-anxiety), and Clinical Global Impression-Sleep Scale (CGI-sleep). Results: Among 180 patients, no differences in demographic characteristics among the three benzodiazepine groups were noted. After six weeks of treatment, all benzodiazepine groups showed significant improvements in CGI-S, CGI-anxiety, and CGI-sleep scores ( p <0.001). There were no differences in mean changes in CGI-S, CGI-anxiety and CGI-sleep among the three benzodia-zepine groups. The incidence of side effects was significantly lower in the clonazepam group than with the other benzodiazepines. The incidences of adverse events for the clonazepam, alprazolam, and lorazepam groups were 26.7% (n=20), 48.4% (n=31), and 43.9% (n=18), respectively. Conclusion: The present study suggests that clonazepam is as efficacious as other benzodiazepines for the treatment of various anxiety disorders. Furthermore, the safety profile of clonazepam was superior to the other benzodiazepines in this study.

      • 지역계획의 지역투자 촉진효과 분석

        황홍민 ( Hong Min Huang ),왕기공 ( Ji Kong Wang ),김민영 ( Min Young Kim ) 한국지역발전학회 2010 지역발전연구 Vol.10 No.1

        개혁개방 이래, 각 시기의 지역경제발전 상황에 따라 중국은 서로 다른 지역계획정책을 제시하였다. 이와 같은 지역계획정책은 정부의 직접적인 자금이전과 건설투자, 투자환경 개선 등을 통해 계획지역에게 강력한 투자촉진 효과를 가져왔을 뿐만 아니라, 경제발전에도 큰 도움이 되었다. 본 연구는 중국의 거시적 지역계획전략의 변화 추이를 분석하고, 개혁개방 이래 지역계획정책의 실시 효과를 고찰하며, 지난 몇 년간 새로 제시하고 통과된 지역계획을 분석함으로써 지역계획이 지역투자에게 어떠한 촉진 효과를 가져왔는지를 찾아내고자 한다. 본 연구의 결과, 지역계획이 지역투자에게 현저한 촉진 효과를 가져오는 것이 검증되었고, 그 효과는 지역계획정책이 제시된 시기에 가장 현저하였음을 알 수 있었다. 改革開放以來,中國針對不同時期的地區經濟發展狀況,提出了不同的區域規劃政策。這些區域規劃政策通過政府的直接財政轉移,直接建設投資或者投資環境的優化政策,爲規劃地區提供了有力的投資拉動支持,幷進而推動了經濟建設。本文通過分析中國宏觀區域規劃戰略的演變趨勢,幷回顧了改革開放以來的區域規劃政策的實施效果,以及通過分析近幾年新提出和通過的區域規劃,來總結區域規劃對於地區投資的拉動作用。經過分析,區域規劃對於地區投資的拉動作用顯著存在,幷且在區域規劃政策提出時最爲顯著。

      • KCI등재

        A Study of Correlation among Bone Mineral Density, Body Composition and Body Circumference on 20's Women

        Sang Min Lee,Joong San Wang,Sung Kyu Park,Hong Rae Kim,Jin Hee Ko,Yu Jung Oh,Hae Ran Yoon,Ji Sung Kim 국제물리치료학회 2012 Journal of International Academy of Physical Ther Vol.3 No.1

        The aim of this study was to investigate the correlation among bone mineral density(BMD), body composition and body circumference on 20's college women in Hwaseong. A total of 86 subjects were measured with BMD and body composition and body circumference. To evaluate the correlation between BMD and body composition, bone density and body weight, body mass index(BMI), lean body mass, muscle mass, fat mass and body fat mass were compared. The results of this study, weight was considered the strong correlation with BMD than the height and BMI seems to be greater significance rather than the lumbar spine and femur BMD. In addition, the relationship between body composition and BMD, lean body mass, muscle mass, body fat mass were the most relevant factors and BMD. The relationship between BMD and body circumference that have been difficult because of not enough previous studies but somewhat the study showed that association.

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