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( Yukihiro Yano ),( Hiroyuki Kagawa ),( Seigo Kitada ),( Masahide Mori ),( Soichiro Yokota ),( Ryoji Maekura ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: To date, the clinical signifi cance of Mycobacterium (M.) gordonae isolated from respiratory specimens has not been well investigated. This study aimed to determine the clinical signifi cance of M. gordonae isolated from respiratory specimens and the validity of the diagnostic guideline for pulmonary nontuberculous mycobacterial (NTM) disease as applied patients with M. gordonae. Methods: A retrospective observational study was conducted on all patients from whom M. gordonae was isolated between 2003 and 2013 in our institution, which is a specialist hospital for respiratory disease in Osaka, Japan. M. gordonae was identifi ed by the DNA-DNA hybridization method. We identifi ed patients who met diagnostic criteria according to the guideline of the American Thoracic Society (ATS) for pulmonary NTM disease and confi rmed fi nal defi nitive diagnosis of such patients. Results: M. gordonae isolates were found in respiratory specimens from 152 patients who were examined multiple times. A total of 10 patients met the diagnostic criteria based on pulmonary symptoms, abnormal radiographic fi ndings, and multiple identifi cations of M. gordonae from respiratory specimens. Among these 10 patients, only 2 were confi rmed as having pulmonary disease caused by M. gordonae. Colonization or contamination was diagnosed in the remaining 150 patients. The ratio of patients confi rmed as having pulmonary disease caused by M. gordonae to those from whom M. gordonae was isolated, was 2/152 (1.32%). The positive predictive value of the ATS guideline for pulmonary NTM disease when applied to patients with M. gordonae was 20% (2/10 patients). Conclusions: Occurrence of pulmonary disease caused by M. gordonae was rare and the present ATS guideline for pulmonary NTM disease may be inappropriate when applied to patients with M. gordonae.
Satoru Kikuchi,Tetsushi Kubota,Shinji Kuroda,Masahiko Nishizaki,Shunsuke Kagawa,Hironari Kato,Hiroyuki Okada,Toshiyoshi Fujiwara 대한소화기내시경학회 2019 Clinical Endoscopy Vol.52 No.4
Endoscopic ultrasound (EUS)-guided transgastric drainage has been performed as a less invasive procedure for pancreatic fistulasand intra-abdominal abscesses occurring after surgery in recent years. However, there are no reports of EUS-guided transgastricdrainage of intra-abdominal abscesses following gastrectomy. This case report describes 2 patients who developed an intra-abdominalabscess following gastrectomy and underwent EUS-guided transgastric drainage. Both patients underwent laparoscopy-assisted distalgastrectomy with Billroth-I reconstruction for gastric cancer. The intra-abdominal abscesses were caused by postoperative pancreaticfistula that developed following gastrectomy. One patient underwent naso-cystic drainage and the other underwent only a needlepuncture of the abscess cavity. EUS-guided drainage was performed safely and effectively, although 1 patient developed gastroduodenalanastomotic leakage related to this procedure. In summary, EUS-guided transgastric drainage is safe and technically feasible evenin post-gastrectomy patients. However, it is necessary to be careful if this procedure is performed in the early period followinggastrectomy.