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      • Poster Session:PS 0572 ; Oncology : Lung Cancer with Revealing Skin Metastasis

        ( Miguel Arderius ),( Nayive Gomez ),( David Fortes ),( Alda Jordao ),( Gloria Silva ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Introduction: Skin metastization is an uncommon manifestation of carcinomas (3-4% incidence in some series). Lung origin is more common in men (24 versus 4% in women, in recent meta-analysis), being the fi rst manifestation in 0.8% of cases. It appears in advanced stage and has poor prognosis. Case Presentation: 78 year old man, smoker, went to the ER because of the appearance, in the last 3 months, of 2 cutaneous nodules in the thorax, with progressive enlargement and infi ammatory signs. Concomitantly, he showed asthenia, adynamia, anorexia, exertional dyspnea and weight loss (10kg), symptoms the patient didn`t quite value, showing a very good Performance Status (Karnofsky scoring 70%). In observation, 2 solid subcutaneous nodules (3cm), parasternal, violaceous, ulcerated, non adherent, painful; and 2 similar nodules, smaller and non ulcerated, palpable in the inguinal regions. In the thorax radiography, peribronchial mass on the right, with irregular contour. Thoraco-abdomino-pelvic CT showed a perihilar mass (8cm) in the right lung, obliterating the anterior segment of the superior lobe; pulmonary artery compression; mediastinal pleura invasion; multiple adenomegalies; adrenal gland metastization; and subcutaneous masses in the anterior thoracic wall, abdominal wall and gluteal region. Analytically, elevated NSE (142μg/L). Bronchofi broscopy revealed complete bronchial obstruction, with the biopsy confi rming a Small Cell Carcinoma. The biopsies from the skin lesions had a mixed pattern (Combined Small Cell and Large Cell Neuroendocrine Carcinoma). He was discharged to Pneumological Oncology, where he started chemotherapy. Conclusion: Despite the fact that skin metastasis are rare, it`s timely recognition may be critical to the prognosis. The Internist should therefore be aware of its existence. In this case, the patient kept a good performance status despite the advanced disease.

      • SCIESCOPUSKCI등재

        Clitoria ternatea L. as a Potential High Quality Forage Legume

        Abreu, Matheus Lima Correa,Vieira, Ricardo Augusto Mendonca,Rocha, Norberto Silva,Araujo, Raphael Pavesi,Gloria, Leonardo Siqueira,Fernandes, Alberto Magno,Lacerda, Paulo Drude De,Junior, Antonio Gesu Asian Australasian Association of Animal Productio 2014 Animal Bioscience Vol.27 No.2

        Samples of Clitoria ternatea L. (Cunh$\tilde{a}$) were harvested at 35, 50, 70, and 90 d after a uniformity harvest in a field study designed as a completely randomized design with a total of 18 experimental plots. The dry matter yield of the whole plant was separated quantitatively into leaves, stems, and pods at each harvesting age. Chemical analyses and in vitro gas production kinetics were performed to assess the quality of the plant parts. Yields, chemical composition, and estimates of gas production parameters were analyzed by fitting a mixed statistical model with two types of covariance structures as follows: variance components and an unrestricted structure with heterogeneous variances. Fast and slow gas yielding pools were detected for both leaves and stems, but only a single pool was detected for pods. The homoscedasticity assumption was more likely for all variables, except for some parameters of the gas production kinetics of leaves and stems. There was no presence of typical pods at 35 and 50 d. In the leaves, the fibrous fractions were affected, whereas the non-fibrous fractions were unaffected by the harvesting age. The harvesting age affected the majority of the chemical constituents and gas kinetic parameters related to the stems. The leaves of this legume were the least affected part by the aging process.

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