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      • Implementation of Biorthogonal Wavelet Transform Using Windowed APDF Based on DCT

        Xiao Zhou,Qiming Fu,Fanfan Yang,Chengyou Wang 보안공학연구지원센터(IJSIP) 2014 International Journal of Signal Processing, Image Vol.7 No.6

        All phase digital filter (APDF) is a new type of linear phase FIR digital filter that was proposed in recent years. Firstly, the theory of biorthogonal wavelet transform and windowed APDF based on DCT is expounded and the relationship between them is discussed. Secondly, a novel algorithm is proposed to implement biorthogonal wavelet transform by using windowed APDF based on DCT. As an important application of biorthogonal wavelet transform, multi-resolution analysis of 2-D image signal could be used to test the feasibility and applicability of the proposed algorithm. Finally, the simulation results using MATLAB tool are shown in this paper and the analysis indicates that the proposed method performs well.

      • KCI등재

        Blind Color Image Watermarking Based on DWT and LU Decomposition

        ( Dongyan Wang ),( Fanfan Yang ),( Heng Zhang ) 한국정보처리학회 2016 Journal of information processing systems Vol.12 No.4

        In watermarking schemes, the discrete wavelet transform (DWT) is broadly used because its frequency component separation is very useful. Moreover, LU decomposition has little influence on the visual quality of the watermark. Hence, in this paper, a novel blind watermark algorithm is presented based on LU transform and DWT for the copyright protection of digital images. In this algorithm, the color host image is first performed with DWT. Then, the horizontal and vertical diagonal high frequency components are extracted from the wavelet domain, and the sub-images are divided into 4×4 non-overlapping image blocks. Next, each sub-block is performed with LU decomposition. Finally, the color image watermark is transformed by Arnold permutation, and then it is inserted into the upper triangular matrix. The experimental results imply that this algorithm has good features of invisibility and it is robust against different attacks to a certain degree, such as contrast adjustment, JPEG compression, salt and pepper noise, cropping, and Gaussian noise.

      • SCOPUSKCI등재

        Blind Color Image Watermarking Based on DWT and LU Decomposition

        Wang, Dongyan,Yang, Fanfan,Zhang, Heng Korea Information Processing Society 2016 Journal of information processing systems Vol.9 No.3

        In watermarking schemes, the discrete wavelet transform (DWT) is broadly used because its frequency component separation is very useful. Moreover, LU decomposition has little influence on the visual quality of the watermark. Hence, in this paper, a novel blind watermark algorithm is presented based on LU transform and DWT for the copyright protection of digital images. In this algorithm, the color host image is first performed with DWT. Then, the horizontal and vertical diagonal high frequency components are extracted from the wavelet domain, and the sub-images are divided into $4{\times}4$ non-overlapping image blocks. Next, each sub-block is performed with LU decomposition. Finally, the color image watermark is transformed by Arnold permutation, and then it is inserted into the upper triangular matrix. The experimental results imply that this algorithm has good features of invisibility and it is robust against different attacks to a certain degree, such as contrast adjustment, JPEG compression, salt and pepper noise, cropping, and Gaussian noise.

      • KCI등재

        Metastatic pattern of ovarian cancer delineated by tracing the evolution of mitochondrial DNA mutations

        Xu Zhiyang,Zhou Kaixiang,Wang Zhenni,Liu Yang,Wang Xingguo,Gao Tian,Xie Fanfan,Yuan Qing,Gu Xiwen,Liu Shujuan,Xing Jinliang 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-

        Ovarian cancer (OC) is the most lethal gynecologic tumor and is characterized by a high rate of metastasis. Challenges in accurately delineating the metastatic pattern have greatly restricted the improvement of treatment in OC patients. An increasing number of studies have leveraged mitochondrial DNA (mtDNA) mutations as efficient lineage-tracing markers of tumor clonality. We applied multiregional sampling and high-depth mtDNA sequencing to determine the metastatic patterns in advanced-stage OC patients. Somatic mtDNA mutations were profiled from a total of 195 primary and 200 metastatic tumor tissue samples from 35 OC patients. Our results revealed remarkable sample-level and patient-level heterogeneity. In addition, distinct mtDNA mutational patterns were observed between primary and metastatic OC tissues. Further analysis identified the different mutational spectra between shared and private mutations among primary and metastatic OC tissues. Analysis of the clonality index calculated based on mtDNA mutations supported a monoclonal tumor origin in 14 of 16 patients with bilateral ovarian cancers. Notably, mtDNA-based spatial phylogenetic analysis revealed distinct patterns of OC metastasis, in which a linear metastatic pattern exhibited a low degree of mtDNA mutation heterogeneity and a short evolutionary distance, whereas a parallel metastatic pattern showed the opposite trend. Moreover, a mtDNA-based tumor evolutionary score (MTEs) related to different metastatic patterns was defined. Our data showed that patients with different MTESs responded differently to combined debulking surgery and chemotherapy. Finally, we observed that tumor-derived mtDNA mutations were more likely to be detected in ascitic fluid than in plasma samples. Our study presents an explicit view of the OC metastatic pattern, which sheds light on efficient treatment for OC patients.

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