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RISS 인기검색어
- 검색키워드
- 저자 : ( Defeng Zhang ) (검색결과 5 건)
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( Qianqian Zhang ),( Xiehao Wang ),( Defeng Zhang ),( Meng Long ),( Zhenbing Wu ),( Yuqing Feng ),( Jingwen Hao ),( Shuyi Wang ),( Qian Liao ),( Aihua Li ) 한국미생물생명공학회(구 한국산업미생물학회) 2019 Journal of microbiology and biotechnology Vol.29 No.8
Fish mycobacteriosis is a common bacterial disease in many species of freshwater and marine fish and has caused severe loss of fish production. Mycobacterium marinum has been the most prevalent pathogen observed in several outbreaks of mycobacteriosis of farmed sturgeons in China. However, the immune responses and pathology of sturgeons in mycobacterial infection are rarely studied. Therefore, we used the Illumina RNA-seq method to analyze the transcriptome profile of Acipenser schrenckii challenged with Mycobacterium marinum. To begin, 168,220 non-redundant contigs were acquired from the infection and control groups, and among these, 33,225 contigs have acquired annotations. A total of 4,043 differently expressed (DE) contigs between the two groups were identified, and among these, 2479 were upregulated and 1564 were down-regulated in the infected fish. A total of 1,340 DE contigs with acquired annotations in KEGG were enriched for 124 pathways including the TNF signaling pathway, and the Toll-like receptor signaling pathway. The roles of DE genes involved in significant pathways and other processes were discussed. The 2,209 DE contigs that have yet to acquire proper annotation may represent candidate genes associated with infection in sturgeons and are expected to serve as immunogenetic resources for further study. To our best knowledge, this is the first transcriptome study on sturgeons under bacterial infection.
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Zhang, Yanjun,Nian, Tingkai,Zheng, Defeng,Zheng, Lu Techno-Press 2016 Geomechanics & engineering Vol.11 No.4
Steep rock slope with water-filled tension crack will happen to overturn around the toe of the slope under seismic loading. This failure type is completely different from the common toppling failure occurring in anti-dipping layered rock mass slopes with steeply dipping discontinuities. This paper presents an analytical approach to determine the seismic factor of safety against overturning for an intact rock mass slope with water-filled tension crack considering horizontal and vertical seismic coefficients. This solution is a generalized explicit expression and is derived using the moment equilibrium approach. A numerical program based on discontinuous deformation analysis (DDA) is adopted to validate the analytical results. The parametric study is carried out to adequately investigate the effect of horizontal and vertical seismic coefficients on the overall stability against overturning for a saturated rock slope under two water pressure modes. The analytical results show that vertically upward seismic inertia force or/and second water pressure distribution mode will remarkably decrease the slope stability against overturning. Finally, several representative design charts of slopes also are presented for the practical application.
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Basement Design for Vibration Reduction of High-Rise Buildings under Metro Operation
Zhaowei Chen,Song Peng,Defeng Zeng,Qinglie He,Jing Tang,Mengqi Zhang 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.4
Vibration induced by metro operation on the underground line is transmitted to the buildings above the line, which adversely affects on the normal life and work of human in the building. To study this problem, based on the plate-shell vibration theory, a plate-column-plate coupled model is constructed to analyze the influence of plate thickness, plate elastic modulus and column arrangement on the vibration in mechanism firstly. Relying on a practical engineering problem, two models are established, namely a train-track coupled dynamic model and a monolithic track bed-tunnel-soil-building model, loading fastener force from the train-track coupled dynamic model on the monolithic track bed, vibration propagates to high-rise building through soil-building coupling. Field test is conducted to verify the reliability of the numerical model. On the basis, the vibration law of building under different basement floor thicknesses, basement floor material and arrangement of non-permanent columns are studied. Results show that changing the basement design parameters has different effects. The Z vibration level of building floor decreases with the increase of basement floor thickness. Basement floor thickness increases by 0.02 m, the Z vibration level of the floor decreased by 1.4 – 2.2 dB at most. The decrease of elastic modulus leads to a slight decrease of the Z vibration level of building, the change is less than 1 dB. Without changing the arrangement of basement load-bearing columns, reducing non-permanent structural columns significantly reduces the Z vibration level, with attenuation of up to 5.1 dB.
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Optimization and simulation of the operational motion of a pantograph: Uplift and retraction
Fang Jia,Fengyu Xu,Hang Zhou,Defeng Zhang,Zhijie Xia 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.1
A single-arm pantograph of metro train was studied in this work. The mathematical model of a single-arm pantograph was first established and an optimal design method to obtain the geometric parameters of the pantograph was proposed. The 3D model for the pantograph was then built and the simulation was performed by using virtual prototyping technology to ensure superior performance of the optimized pantograph. The fatigue test of pantograph-insulator system was performed under two operating conditions: Electric pantograph lifting and real train operation. Fatigue test results validated the stability of the optimized pantograph system.
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Fang Jia,Fengyu Xu,Zhijie Xia,Hang Zhou,Defeng Zhang 대한기계학회 2016 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.30 No.10
The power of a metro vehicle is supplied by the pantograph on the vehicle roof. During pantograph lifting, the insulator set of the pantograph is prone to fracture caused by the impact load. In this work, a Single-arm pantograph–insulator system (SPIS) of metro vehicles was studied for the fatigue fracture of the insulator set induced by impact load. The basic structure of the SPIS was first introduced. The dynamic axial force test and fatigue and fracture damage experiments was then conducted on SPIS for both simulation experiment platform and real vehicles to analyze the causes of the insulator fracture. A method to improve the design structure of the back-end insulator set was proposed to resolve the problems of both the impact failure of the insulator steel core and the stress concentration on the interface between a steel core and an epoxy resin. The finite element analysis results indicated that the improved insulator set shows a much smaller stress concentration. Therefore, the improved insulator set has a greatly reduced fatigue damage subjected to shear effect, which validated the feasibility of the improved structure design.
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