A New Unsymmetrical Zinc Phthalocyanine as Photosensitizers for Dye-sensitized Solar Cells

Dan Zhang,Xue-Jun Zhang,Lei Zhang,Li-Jun Mao 대한화학회 2012 Bulletin of the Korean Chemical Society Vol.33 No.4

A new unsymmetrical zinc phthalocyanine has been designed and synthesized based on the ‘push-pull’ and extended π-conjugation concept for the dye-sensitized solar cells. Three tert-butoxy groups, which act as electron releasing (‘push’), enhance the solubility of phthalocyanine in common organic solvents and reduce the aggregation. Hydroxy substituted 9,10-anthraquinones act as electron acceptors (‘pull’) for the study of photoinduced electron transfer processes as well as grafting onto nanocrystalline TiO2. The new unsymmetrical zinc phthalocyanine was fully characterized by FTIR, UV-vis, 1H NMR, cyclic voltammetry and differential pulse voltammetry. The new sensitizer was tested in dye-sensitized solar cells, and gave a better performance.

A New Unsymmetrical Zinc Phthalocyanine as Photosensitizers for Dye-sensitized Solar Cells

Zhang, Dan,Zhang, Xue-Jun,Zhang, Lei,Mao, Li-Jun Korean Chemical Society 2012 Bulletin of the Korean Chemical Society Vol.33 No.4

A new unsymmetrical zinc phthalocyanine has been designed and synthesized based on the 'push-pull' and extended ${\pi}$-conjugation concept for the dye-sensitized solar cells. Three tert-butoxy groups, which act as electron releasing ('push'), enhance the solubility of phthalocyanine in common organic solvents and reduce the aggregation. Hydroxy substituted 9,10-anthraquinones act as electron acceptors ('pull') for the study of photoinduced electron transfer processes as well as grafting onto nanocrystalline $TiO_2$. The new unsymmetrical zinc phthalocyanine was fully characterized by FTIR, UV-vis, $^1H$ NMR, cyclic voltammetry and differential pulse voltammetry. The new sensitizer was tested in dye-sensitized solar cells, and gave a better performance.

Perioperative Comprehensive Supportive Care Interventions for Chinese Patients with Esophageal Carcinoma: a Prospective Study

Zhang, Xiao-Dan,Zhao, Qing-Yu,Fang, Yi,Chen, Guan-Xuan,Zhang, Hui-Fang,Zhang, Wen-Xiao,Yang, Xiao-Ping Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.12

Objective: To assess the effects of perioperative comprehensive supportive care interventions on outcome of Chinese esophageal cancer patients in a prospective study. Methods: 60 patients with primary esophageal carcinoma were randomized into an intervention group (IG, n=31) and a control group (CG, n=29). The Chinese version of symptom checklist-90 (SCL-90) was adopted to assess their psychological status. The interventions, including health education, psychological support, stress management, coping strategies and behavior training, were carried out in 3 phases (preoperative, postoperative I and postoperative II), and psychological effects were thereafter evaluated accordingly before surgery, and 1 week, 4 weeks and 24 weeks post-surgery. Medical costs were estimated at discharge. Survival of patients was estimated each year post-surgery. General health status and satisfaction-with-hospital were surveyed by a follow-up questionnaire 4 years post-surgery. Results: All the subjects demonstrated higher scores in the preoperative phase than the normal range of Chinese population concerning 7 psychological domains including somatization, obsessive-compulsive, depression, anxiety, hostility, phobic anxiety and paranoid ideation. Although no significant difference was observed between the two groups at admission, the scores of IG, which tended to decrease at a faster rate, were generally lower than those of CG at weeks 1, 4 and 24 post-surgery. The length of hospital stay and medical costs of IG were significantly less than those of CG and satisfaction-with-hospital was better. However, there was no significant difference in 4-year survival or health status between two groups. Conclusions: Appropriate perioperative comprehensive supportive care interventions help to improve the psychological state of Chinese patients with esophageal carcinoma, to reduce health care costs and to promote satisfaction of patients and their families with hospital.

Distinct Pro-Apoptotic Properties of Zhejiang Saffron against Human Lung Cancer Via a Caspase-8-9-3 Cascade

Liu, Dan-Dan,Ye, Yi-Lu,Zhang, Jing,Xu, Jia-Ni,Qian, Xiao-Dong,Zhang, Qi Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15

Lung cancer is the leading cause of cancer-related death worldwide. Here we investigated the antitumor effect and mechanism of Zhejiang (Huzhou and Jiande) saffron against lung cancer cell lines, A549 and H446. Using high performance liquid chromatography (HPLC), the contents of crocin I and II were determined. In vitro, MTT assay and annexin-V FITC/PI staining showed cell proliferation activity and apoptosis to be changed in a dose- and time-dependent manner. The inhibition effect of Jiande saffron was the strongest. In vivo, when mice were orally administered saffron extracts at dose of 100mg/kg/d for 28 days, xenograft tumor size was reduced, and ELISA and Western blotting analysis of caspase-3, -8 and -9 exhibited stronger expression and activity than in the control. In summary, saffron from Zhejiang has significant antitumor effects in vitro and in vivo through caspase-8-caspase-9-caspase-3 mediated cell apoptosis. It thus appears to have more potential as a therapeutic agent.

Fabrication of Photopolymer Hierarchical Micronanostructures by Coupling Electrospinning and Photolithography for SERS Substrates

Wen-Yi Zhang,Xin-Ze Xiao,Chao Lv,Jia Zhao,Gong Wang,Xuan Gu,Ran Zhang,Bin-Bin Xu,Dan-Dan Zhang,Ai-Wu Li,Yong-Lai Zhang,Hong-Bo Sun 한국고분자학회 2013 Macromolecular Research Vol.21 No.3

Reported here is the fabrication of photopolymer hierarchical micronanostructures through a combinative process of electrospinning and subsequent photolithography. Electrospun SU-8 (epoxy-based negative photoresist)nanofiber films have been patterned into gratings with periods of 100, 200, 300, and 400 μm, respectively. Deposition of a silver nanolayer on these interlaced nanofiber films would lead to the formation of various plasmonic nanostructures,and therefore, giving rise to abundant surface-enhanced Raman scattering (SERS) “hot spots”. In the detection of Rhodamine 6G (R6G), probing molecule, the resultant SERS substrates show both high sensitivity and good reproducibility. The SERS enhancement factor could reach as high as ~108, indicating high efficiency. The fabrication of patterned, highly efficient SERS substrates may hold a great promise for the integration of SERS substrates in various microdevices such as microfluidic chips.

Improvement of Poly(γ-glutamic acid) Biosynthesis and Quantitative Metabolic Flux Analysis of a Two-stage Strategy for Agitation Speed Control in the Culture of Bacillus subtilis NX-2

Dan Zhang,Zongqi Xu,Hong Xu,Xiaohai Feng,Sha Li,Heng Cai,Yan Wei,Pingkai Ouyang 한국생물공학회 2011 Biotechnology and Bioprocess Engineering Vol.16 No.6

In this study, the production of poly(γ-glutamic acid) by Bacillus subtilis NX-2 (PGA) at different agitation speeds was investigated. Based on the analysis of specific cell growth rate (μ) and specific PGA formation rate (q_p),a two-stage strategy for agitation speed control was proposed. During the first 24 h, an agitation speed of 600rpm was used to maintain a high μ for better cell growth,which then reduced to 400 rpm after 24 h to maintain a high qp to enhance PGA production. Using this method, the maximum concentration of PGA reached 40.5 ± 0.91 g/L and the PGA productivity was 0.56 ± 0.012 g/L/h, which was 17.7 and 9.8% higher, respectively, than the best results obtained when a constant agitation speed was used. The flux distributions and the related enzymes of 2-oxoglutarate could be affected by this two-stage strategy for agitation speed. The activity of isocitrate dehydrogenase and glutamate dehydrogenase at the key node of 2-oxoglutarate increased, and more flux distribution was directed to glutamate. The flux distribution from extracellular to intracellular glutamate also increased and improved PGA production as the glutamate uptake rates increased using the agitation-shift control method.

Research of Regional Forest Fire Prediction Method based on Multivariate Linear Regression

Dan Liu,Yanrong Zhang 보안공학연구지원센터 2015 International Journal of Smart Home Vol.9 No.1

In order to achieve the predicted speed, high accuracy, the use of simple purpose, forest fire prediction of the key issues is to choose the main predictors. Forest fire prediction involves many factors, some of which are stable factors such as climate, topography, forest characteristics; and some unstable factors, such as fuel moisture content, meteorological factors, and other sources of ignition. Currently leading factor in the prediction of forest fire is often used in the fuel moisture, precipitation or dry days, relative humidity, temperature and wind five factors. In this paper, some of the data Yichun fire nearly a decade predict the forest fire meteorological data analysis, using multivariate linear regression to derive forest fire prediction method in the wireless sensor networks.

Residual detection of buparvaquone, nystatin, and etomidate in animal-derived food products in a single chromatographic run using liquid chromatography-tandem mass spectrometry

Zhang, Dan,Park, Jin-A.,Abd El-Aty, A.M.,Kim, Seong-Kwan,Cho, Sang-Hyun,Wang, Yanmei,Shim, Jae-Han,Jeong, Ji Hoon,Shin, Sung Chul,Kim, Jin-Suk,Chang, Byung-Joon,Shin, Ho-Chul Elsevier 2017 Food chemistry Vol.237 No.-

<P><B>Abstract</B></P> <P>A reliable and highly sensitive screening method based on liquid chromatography coupled withtriple-quadrupoleelectrospray tandemmass spectrometry (LC-MS/MS) analysis has been developed for the detection and quantification of three veterinary drugs, including buparvaquone, nystatin, and etomidate impurity B CRS. The tested drugs were extracted from samples of porcine muscle, pasteurized whole milk, and eggs using 10mM ammonium formate in acetonitrile followed by liquid-liquid purification with <I>n</I>-hexane. Chromatographic separation was achieved on a Phenomenex Luna C18 analytical column using 0.1% formic acid in ultrapure water (A) and acetonitrile (B) as mobile phases. All the matrix-matched calibration curves were linear (<I>R<SUP>2</SUP> </I> ≥0.9756) over the concentration levels of the drugs tested. Recovery at two spiking levels (equivalent to the limit of quantification (LOQ)=5ng/g and 2×LOQ) ranged from 72.88% to 92.59% with intra- and inter-day precisions <17%, except for porcine muscle spiked with 5ng/g nystatin (RSD=25.15%). Samples collected from markets located in Seoul, Republic of Korea, tested negative for all the drugs analyzed. In summary, this method is suitable for screening and quantifying the selected drugs in a single chromatographic run and with high selectivity in animal-derived food products meant for human consumption.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Buparvaquone, nystatin, and etomidate were analyzed in animal-derived food products using LC-MS/MS. </LI> <LI> A combination of 10mM ammonium formate in acetonitrile and <I>n</I>-hexane is sufficient to effectively extract the drugs without SPE. </LI> <LI> The performance parameters were satisfactory and acceptable. </LI> <LI> The target analytes were not detected in any of the market samples. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Collaborative Filtering Algorithm based on User in Cloud Computing

Dan Zhang 보안공학연구지원센터 2016 International Journal of Grid and Distributed Comp Vol.9 No.12

The user-based collaborative filtering algorithm has been widely used in various kinds of personalized recommendation systems. But it has a serious shortcoming: with the increasing number of the users and commodities, its calculation work grows rapidly. To address the problem of vast time consumption by big dataset, we utilize MapReduce programming idea to do parallelized transformation of the algorithm; finally deploy it to be run in Hadoop cloud computing platform. Experiments have revealed that if computing data is reasonably distributed and the data volume is big, then the algorithm performance of the algorithm can realize favorable linearly speeding effect.

Controlled synthesis of Co₂C nanochains using cobalt laurate as precursor: Structure, growth mechanism and magnetic properties

Zhang, Yajing,Zhu, Yuan,Wang, Kangjun,Li, Da,Wang, Dongping,Ding, Fu,Meng, Dan,Wang, Xiaolei,Choi, Chuljin,Zhang, Zhidong Elsevier 2018 Journal of magnetism and magnetic materials Vol.456 No.-

<P><B>Abstract</B></P> <P>Cobalt carbides (Co<SUB>2</SUB>C and Co<SUB>3</SUB>C) nanocomposites exhibit interesting hard magnetic property, controlled synthesis of individual phase facilitates to clarify the magnetism of each, but it is difficult to obtain the single phase. We present a new approach to address this issue via a polyol refluxing process, using cobalt laurate as the precursor. The single phase Co<SUB>2</SUB>C magnetic nanochains self-assembled by nanoparticles are synthesized. The precursor is the key factor for controlling the growth kinetics of the Co<SUB>2</SUB>C nanochains. Cobalt, instead of cobalt carbides, is produced if cobalt chloride, acetate and acetylacetonate replace cobalt laurate as the precursor, respectively. The evolution of the growth process has been studied. In the formation of Co<SUB>2</SUB>C, first fcc-Co produces, then it transforms into Co<SUB>2</SUB>C by carbon diffusion process, and the produced carbon first exists in disordered state and then a small amount of them transforms into graphite. Saturation magnetization (<I>Ms</I>) of Co<SUB>2</SUB>C nanochains obtained at 300 °C for 20, 60, and 180 min are 27.1, 18.9, and 10.9 emu g<SUP>−1</SUP>, respectively. The decrease of <I>Ms</I> caused by increasing carbon content, and the carbon content are much larger than the stoichiometric ratio value of Co<SUB>2</SUB>C (9.2 wt%). The Co<SUB>2</SUB>C nanochains have mesoporous pore of 3.8 nm and the specific surface area of 48.6 m<SUP>2</SUP> g<SUP>−1</SUP>.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The Co<SUB>2</SUB>C magnetic nanochains are synthesized using cobalt laurate as the precursor in TEG. </LI> <LI> The precursor of cobalt laurate is the key factor for controlling the growth kinetics of Co<SUB>2</SUB>C nanochains. </LI> <LI> Ms of Co<SUB>2</SUB>C nanochains obtained at 300 °C for 20, 60, and 180 min are 27.1, 18.9, and 10.9 emu g<SUP>−1</SUP>, respectively. </LI> <LI> The decrease of Ms is caused by increasing carbon content with increasing reaction time. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>We present a new approach to obtain single phase Co<SUB>2</SUB>C nanochains by using cobalt laurate as the precursor.</P> <P>[DISPLAY OMISSION]</P>