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박승연(Seung Yeon Park),이정남(Jung Nam Lee),정민(Min Chung),이운기(Un Gi Lee),이영돈(Yeong Don Lee),오재환(Jae Hwan Oho),백정흠(Jung Hum Bak),박연호(Yeon Ho Park),김현영(Hyeon Yeong Kim),김건국(Keon Kuk Kim),최상태(Sang Tae Choi) 대한외과학회 2007 Annals of Surgical Treatment and Research(ASRT) Vol.72 No.2
Appendiceal mucocele is a cystic dilatation of the appendiceal lumen with mucus, which may be caused by either benign or malignant diseases. In this report, five cases of appendiceal mucocele are reported, three of which had a preoperative diagnosis of mucocele, whereas the others were found incidentally during the operation under the diagnosis of intussusception and periappendiceal abscess. All five patients underwent surgical resections, including one ileocecal resection and four right hemicolectomies. Histopathology revealed a mucinous cystadenoma in four cases, and a mucinous cystadenocarcinoma in one. There was no disease-related death during 18 months of follow-up.
김경순(Kyoung Soon KIm),심상희(Sang Hee Shim),정기화(Gi Hwa Jeong),정춘식(Chun Sik Chung),고광호(Kwang Ho Ko),박정일(Jeong Hill Park),허훈(Hoon Huh),이봉진(Bong Jin Lee),김박광(Bak Kwang Kim) 한국응용약물학회 1998 Biomolecules & Therapeutics(구 응용약물학회지) Vol.6 No.4
In the previous screening on antidiabetic effect of Lycii fructus by glucose transport method using N₂-STZ diabeted rat model, each extracts showed the potent antidiabetic activity. We obtained three compounds isolated from the water fraction, EtOAc fraction and n-BuOH fraction of Lycii fructus in the present work and their structures were identified as 1-carboxy-N,N,N-trimethylmethanaminium hydroxide inner salt, 2,4(1H,3H)-pyrimidinedione and 3,3`,4`,5,7-pentahydroxyflavone-3-rutinoside. Among the constituents separated from Lycii fructus, 2,4(1H,3H)-pyrimidinedione, 3,3`,4`,5,7-pentahydroxyflavone-3-rutinoside and ascorbic acid were shown a remarkable antidiabetic effect.
악성 변화를 동반한 십이지장 팽대부의 융모성 선종 1예
박상훈,김진호,최상용,김재선,이창홍,박영태,김종극,원남희,정문기,조상경 대한소화기내시경학회 1994 Clinical Endoscopy Vol.14 No.4
Ampullary adenoma is a benign neoplasm with malignant potential that arises from the glandular epithelium of the ampulla of Vater. When the tumor is confined to the ampulla, abdominal sonogram and CT scan can show dilatation of the common bile duct or pancreatic duct, but the mass itself may not be seen. And even biopsies are done, the confirmation of malignant change is frequently missed, and it may be impossible to assess the presence of carcinoma in situ or invasive carcinoma without complete exicision of the lesion. So complete surgical resection is recommended because of extensive growth of the ampullary adenoma and its malignant potential. Recently, we experienced a case of about 0.8 x 1.0 cm sized tumor of the ampulla of Vater that was diagnosed as villous adenoma on endoscopic biopsy, and malignant change was found on resected surgical specimen.
김종호(Jong Ho Kim),김경순(Kyoung Soon KIm),박정일(Jeong Hill Park),이봉진(Bong Jin Lee),허훈(Hoon Huh),정기화(Gi Hwa Jeong),정춘식(Chun Sik Chung),김박광(Bak Kwang Kim) 한국응용약물학회 1996 Biomolecules & Therapeutics(구 응용약물학회지) Vol.4 No.3
For the screening of antidiabetic effect, this study was carried out to some natural products by measurements of glucose level. MeOH and CH₂Cl₂ extracts of natural products were investigated for the effect on glucose level of N₂-STZ diabeted Rat. Among the natural products, Dioscorea Rhizoma, Trichosanthes Radix, Nelumbis Semem and Lycii Fructus were shown a remarkable antidiabetic effect.