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      • Diagnosis and Management of Benign Central Airway Stenosis: Experience from Vietnam

        ( Ngo Quy Chau ),( Giap Vu Van ),( Du Nguyen Ngoc ),( Duc Hoang Anh ) 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.0

        Introduction We present a brief review on the diagnosis and management of the central airway obstruction (CAO) in particular nonmalignant CAO. There are multiple causes. The laryngotracheal stenosis is frequently caused by prolong intubation or tracheostomy with the cuff injury, stomal stenosis, tube tip granulations. The patients with CAO may have non-typical clinical signs such as cough, stridor, wheezing. It is easily overlooked or misdiagnosed. Most patients do not complain of dyspnea until the lumen of the central airway is obstructed by approximately 50%. The first paraclinical exam indicated is Chest CT scans with 2 D or 3 D rendering of tracheo-bronchial tree but the bronchoscopy permit the diagnosis, evaluation of the lesion with degree, location and morphological classsification of stenosis. The management of benign airway stenosis require a multidiscipline team discussion with two options: surgical resection and interventional bronchoscopy. There bronchoscopic interventions with their advantages and inconveniences are discussed: bronchoplasty, electrocautery and airway stent. We present some Experiences from Bach Mai hospital, Vietnam Case 1: 43-year-old male patient was admitted for dyspnea. He had motorcycle accident 2 months before, after the accident, the patient was comatose, had IMV for 1 month. Bronchoscopy: severe membranous stenosis of the subglottic segment, 3cm from the vocal cords. He had intervention with electrocautery then balloon dilation with good success. Case 2: Male patient, 57 years old, admitted to Bach Mai hospital due to wheezing, shortness of breath 3 weeks ago. He had hospital-acquired pneumonia treated at ICU in 2 months, twice intubations, 11 days mechanical ventilation. Bronchoscopy showed membranous stenosis of the trachea, 3cm from the vocal cords. He had intervention with electrocautery then balloon dilation with good success. Case 3: 16-year-old man hospitalized for shortness of breath. History: 6 months before this hospitalization, patients had trafic accident and mechanical ventilation for 2 weeks and tracheostomy. Chest CT: tracheal stenosis above tracheostomy. He had surgical resection of tracheal stenosis but the dyspnea and wheezing persist due to tracheal anastomotic stenosis post operation. After MDT discussion, he had Interventional bronchoscopy - stenting with good success. Case 4: 36 years old male patient, had a traffic accident 4 years ago. He was intubated then tracheostomized. Subsequently, the patient developed tracheal stenosis and had a metallic stent through flexible bronchoscopy. After intervention, metallic stent was displaced many times, the patient had to undergo the surgery to fix the stent to the trachea. For one year, he had many episodes of shortness of breath with wheezing. Chest CT scan and bronchoscopy showed the tracheal stenosis below the metallic stent. He was transfert to BACH MAI hospital. He had surgical remove of metallic stent. A silicone stent was put through rigid bronchoscopy sucessfully. Case 5: A male patient 34 years old. He had a traumatic brain injury requiring craniotomy. After the surgery, the patient presented a tracheal stenosis post intubation. He had long term tracheostomy with several unsuccessful remove. MDT discussion: interventional bronchoscopy with tracheal stent. Due to the fixation of cervical spine post accident, we had first perfomed the tracheotomy then used rigid bronchoscopy to put the tracheal stent through the tracheotomy. In conclusions Tracheal stenosis can be difficult to treat and necessitate a multi-disciplinary approach in order to offer the best available solution for each patient. Intervention Bronchoscopy can provide durable successful results in selected patients. We had bronchoplasty, electrocautery, balloon dilation, rigid bronchoscopy, stent. We need to apply and developpe more other interventional bronchoscopy such as laser.

      • Management of malignant central airway obstruction in a tertiary hospital in viet nam

        ( Giap Vu Van ),( Chau Ngo Quy ),( Ha Pham Ngoc ),( Du Nguyen Ngoc ),( Duc Hoang Anh ) 대한결핵 및 호흡기학회 2019 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.127 No.-

        Objective: To evaluate the causes and treatments of patients with malignant central airway obstruction (CAO). Subjects: 37 patients were diagnosed with malignant CAO at Respiratory Center of Bach Mai Hospital. Methods: Retrospective and Prospective, descriptive study. Results: Average age was 53.8 ± 13.1 years. CAO occurred mainly in the 45-59 age group and in men more than women. No significant differences between the number of patients with cancer originated from in (group 1) and out (group 2) of the airway with regard to the number of patients, degree of stenosis and location of stenosis. In group 1, NSCLC accounted for the majority. In group 2, squamous-cell esophageal carcinoma had the highest proportion. The prevalence of patient having treatment was higher than not having treatment statistically. In the treatment group, the number of participants undergoing a combination of airway stent insertion and balloon dilatation was predominant. There were no significant differences in causes or locations or degrees of stenosis respecting treatment modalities. Participants having comfort after treatment accounted for the majority. In no treatment group and treatment group, cumulative proportions surviving were 0% (at 11th month) and 44.3% (at 9th month), respectively. The survival time in the treatment group (15.1 ± 3.4 months) was statistically longer than in no treatment group (4.4 ± 1.9 months) (p = 0.031). Conclusions: Causes of malignant CAO are varied and induce a variety of location and degree of stenosis, thereby leading to diverse treatments. Clinicians need to consider having appropriate treatments for patients to increase their comfort and survival time.

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