http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
증례 : 감염 ; 면역력이 정상인 환자에서 발생한 중추신경계의 아스페르길루스증 1예
조병현 ( Byung Hyun Joe ),황은정 ( Eun Jung Hwang ),박소연 ( So Youn Park ),손준성 ( Jun Sung Son ),이미숙 ( Mi Suk Lee ) 대한내과학회 2011 대한내과학회지 Vol.80 No.5
침습성 아스페르길루스증은 면역학적으로 저하되어 있는 경우에 흔한 것으로 알려져 있으나 최근 면역학적으로 정상인 자에서 발생하는 빈도가 과거에 비해 증가 추세이며 중추신경계에서 발생하는 경우 그 임상양상이나 방사선학적 소견이 다양하기 때문에 초기 진단이 쉽지 않다. 본 저자들은 면역학적으로 정상인 환자에서 뇌종양 양상으로 중추신경계에 발생한 침습성 아스페르길루스증을 경험하였기에 이를 보고하는 바이다.
A case of molluscum contagiosum treated by ingenol mebutate gel
( Hyun Jae Joe ),( Young Wook Ryoo ),( Sung Ae Kim ),( Byung Ho Oh ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1
In most of cases, Molluscum Contagiosum (MC) is treated by curettage. However, for children, it is often difficult as they fear it. In these cases, topical therapy can be applied as another option. It has been reported that treatment with adapalene, tretinoin, imiquimod, etc. for average 8 months only acquires 50 to 60 percent of cure rate. Ingenol mebutate (IM) is a new topical drug for the field treatment of actinic keratosis, which improves symptoms in short treatment once a day for a couple of days. Recently, it was reported that IM was also effective in the treatment of MC. When applied to the MC lesion, the roof of MC was disrupted, followed by the extraction of molluscum body. Also, it is possible to promote cellular immune reaction against viral infection. We herein report a 5-year old patient with disseminated MC lesions over the whole body for 7 months who was successfully treated by IM.
Joe, Eugene,Lee, Jeong Min,Kim, Kyung Won,Lee, Kyung Bun,Kim, Soo Jin,Baek, Jee Hyun,Shin, Cheong Il,Suh, Kyung Suk,Yi, Nam Joon,Han, Joon Koo,Choi, Byung Ihn Wiley Subscription Services, Inc., A Wiley Company 2012 JOURNAL OF MAGNETIC RESONANCE IMAGING Vol.36 No.5
<P><B>Abstract</B></P><P><B>Purpose:</B></P><P>To evaluate the diagnostic implications of the iterative decomposition of water and fat using echo‐asymmetry and the least‐squares estimation (IDEAL) technique to detect hepatic steatosis (HS) in potential liver donors using histopathology as the reference standard.</P><P><B>Materials and Methods:</B></P><P>Forty‐nine potential liver donors (32 male, 17 female; mean age, 31.7 years) were included. All patients were imaged using the in‐ and out‐of‐phase (IOP) gradient‐echo (GRE) and IDEAL techniques on a 1.5 T MR scanner. To estimate the hepatic fat fraction (FF), two reviewers performed regions‐of‐interest measurement in 15 areas of the liver seen on the IOP images and on the IDEAL‐FF images. The magnetic resonance imaging (MRI) and pathology values of macrosteatosis were correlated using the Pearson correlation coefficient. We analyzed the diagnostic performance of IOP imaging and IDEAL for detecting HS.</P><P><B>Results:</B></P><P>The results of the hepatic‐FF estimated on IDEAL were well correlated with the histologic degree of macrosteatosis (γ = 0.902, <I>P</I> < 0.001). IDEAL showed 100% sensitivity and 91% specificity for detecting HS, and IOP imaging showed 87.5% sensitivity and 97% specificity, respectively.</P><P><B>Conclusion:</B></P><P>IDEAL is a useful tool for the preoperative diagnosis of HS in potential living liver donors; it can also help to avoid unnecessary biopsies in these patients. J. Magn. Reson. Imaging 2012;36:1124–1130. © 2012 Wiley Periodicals, Inc.</P>
A case of dermatofibrosarcoma protuberans treated with slow Mohs micrographic surgery
( Hyun Jae Joe ),( Joon Bum Lee ),( Kyu Suk Lee ),( Sung Ae Kim ),( Byung Ho Oh ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1
Dematofibrosarcoma protuberans(DFSP) is a rare dermal spindle cell tumor which characterized by a slowly progressive local growth and a high recurrence rate after wide excision due to its aggressive, finger-like outgrowth pattern. Mohs micrographic surgery, which ensures complete excision of the tumor and minimizes normal tissue loss, is accepted as the treatment of choice for DFSP. However, the use of frozen section for margin control in DFSP is controversial because it could be difficult to differentiate minimal residual tumor in subcutaneous tissue from normal skin on the frozen sections, and is more challenging in recurrent disease because of the scar tissue. Hence, we report a case of a DFSP treated by slow Mohs micrographic surgery, which used horizontally-cut paraffin-embeded permanent sections for better margin control.
( Hyun Jae Joe ),( Gil Han ),( Byung Ho Oh ),( Kyu Suk Lee ),( Sung Ae Kim ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.1
Sweet syndrome(acute febrile neutrophilic dermatosis) ischaracterized by abrupt onset of fever, leukocytosis, and tender erythematous nodules or plaques. Generally, sweet syndrome does not respond to antibiotic therapy, but steroids are very effective and promptly improve skin lesion. Also, sweet syndrome is associated with a variety of disorders, including hematological malignancies and solid tumors, autoimmune diseases, inflammatory bowel disease, infections, medications, and pregnancy. In this case, a 5-year-old female children visited us who had painful erythematous indurated plaques on Rt. periocular and Lt. zygomaic area after using granulocyte colony-stimulating factor(G-CSF) for aplastic anemia. She was diagnosed as sweet syndrome induced by recombinant G-CSF, which was improved after drug withdrawl and systemic corticosteroid treatment. Herein, we report a very rare case of sweet syndrome in a child with aplastic anemia after receiving recombinant G-CSF.
A case of kerion celsi mistaken for ruptured epidermal cyst
( Hyun Jae Joe ),( Joon Bum Lee ),( Young Wook Ryoo ),( Sung Ae Kim ),( Byung Ho Oh ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1
Kerion celsi is the severe inflammatory infection, caused by a vigorous T-cell mediated host response to the dermatophyte infection. In this case, it can be mistaken for other disease such as cellulitis, impetigo, furuncle, epidermal cyst. M. canis is most likely transmitted by contact of animal hosts such as cats and dogs with humans. We report the 75-year-old female who presented with a 2-month history of tender erythematous scaly plaques with pustules, crusts on Rt. scalp area. At first, from the histopathologic findings of the lesion, the patient was diagnosed epidermal cyst because of cystic-like structure in mid-dermis. But, the fungal culture revealed M. canis as the causative fungus. Herein we report a educational case of kerion celsi mistaken for ruptured epidermal cyst.
( Hyun-jae Joe ),( Jun-il Kwon ),( Byung-ho Oh ),( Young-wook Ryoo ),( Sung-ae Kim ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2
Background: Staphylococcal scalded skin syndrome (SSSS) is a superficial blistering skin disease by S. aureus- mediated exfoliative toxin. Generally, SSSS affects infants and children younger than 5 years and has a good prognosis. But, an increasing number of methicillin- resistant Staphylococcus aureus (MRSA) cases has been reported recently. Objectives: The purpose of this study was to evaluate clinical features and courses, and to investigate microbiological manifestations and antimicrobial susceptibility test of SSSS in Korean children. Methods: From March 2003 to July 2016, a total 141 children were included in this study. The patients were divided into two groups according to the time of onset: before and after September 2011. We retrospectively reviewed medical records, microbiological results, bacterial detection sites and antimicrobial susceptibility tests of all children. Results: S. aureus infection was noted in all children. All of cultured S. aureus in 89 (63.1%) of the 141 patients were methicillin-resistant. Dividing by the September 2011, MRSA shows much higher ratio, 71.7% than previous 38.8%. Also, MRSA was detected on skin, neck, nose each 61, 41, 18 times including the overlap detection. Conclusion: In conclusion, since the MRSA infection is gradually increasing in recent years, careful consideration is needed in antibiotic selection covering MRSA.