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RISS 인기검색어
- 검색키워드
- 저자 : ( Ali Amanat ) (검색결과 4 건)
- 무료
- 기관 내 무료
- 유료
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Dietary and Lifestyle Factors and Risk of Non-Hodgkin's Lymphoma in Oman
Ali, Amanat,Al-Belushi, Buthaina S.,Waly, Mostafa I.,Al-Moundhri, Mansour,Burney, Ikram A. Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2
Background: The incidence of various types of cancers including the non-Hodgkin's lymphoma (NHL) has increased during the recent years. Diet and lifestyle factors have been reported to play an important role in the etiology of NHL. However, no such data are available from the Middle Eastern countries, including Oman. Materials and Methods: Forty-three histologically confirmed cases of non-Hodgkin's lymphoma (NHL) diagnosed at the Sultan Qaboos University Hospital (SQUH) and the Royal Hospital (RH), Muscat, Oman and forty-three age and gender matched controls were the subjects of this study. Frequency matching was used to select the control population. Information on social and demographic data as well as the dietary intake was collected by personal interviews, using a 117-items semi-quantitative food frequency questionnaire. Results: A non-significant increased risk of NHL was observed with higher body mass index (BMI) (OR=1.20, 95%CI: 0.45, 2.93), whereas a significantly decreased risk of NHL was associated with a higher educational level (OR=0.12, 95%CI: 0.03, 0.53). A significantly increased risk was observed for higher intake of energy (OR=2.67, 95%CI: 0.94, 7.57), protein (OR=1.49, 95%CI: 0.54, 4.10) and carbohydrates (OR=5.32, 95%CI: 1.78, 15.86). Higher consumption of daily servings from cereals (OR=3.25, 95%CI: 0.87, 12.09) and meat groups (OR=1.55, 95%CI: 0.58, 4.15) were also found to be associated with risk of NHL, whereas a significantly reduced risk was associated with higher consumption of vegetables (OR=0.24, 95%CI: 0.07, 0.82). The consumption of fruits, milk and dairy products however showed no significant association with the risk of developing NHL. Conclusion: The results suggest that obesity, high caloric intake, higher consumption of carbohydrate and protein are associated with increased risk of NHL, whereas a significantly reduced risk was observed with higher intake of vegetables.
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Waly, Mostafa I.,Ali, Amanat,Guizani, Nejib,Al-Rawahi, Amani S.,Farooq, Sardar A.,Rahman, Mohammad S. Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8
Functional foods include antioxidant nutrients which may protect against many human chronic diseases by combating reactive oxygen species (ROS) generation. The purpose of the present study was to investigate the protective effect of pomegranate peel extract (PPE) on azoxymethane (AOM)-induced colon tumors in rats as an in vivo experimental model. Forty Sprague-Dawley rats (4 weeks old) were randomly divided into 4 groups containing 10 rats per group, and were treated with either AOM, PPE, or PPE plus AOM or injected with 0.9% physiological saline solution as a control. At 8 weeks of age, the rats in the AOM and PPE plus AOM groups were injected with 15 mg AOM/kg body weight, once a week for two weeks. After the last AOM injection, the rats were continuously fed ad-libitum their specific diets for another 6 weeks. At the end of the experiment (i.e. at the age of 4 months), all rats were killed and the colon tissues were examined microscopically for lesions suspected of being preneoplastic lesions or tumors as well as for biochemical measurement of oxidative stress indices. The results revealed a lower incidence of aberrant crypt foci in the PPE plus AOM administered group as compared to the AOM group. In addition, PPE blocked the AOM-induced impairment of biochemical indicators of oxidative stress in the examined colonic tissue homogenates. The results suggest that PPE can partially inhibit the development of colonic premalignant lesions in an AOM-induced colorectal carcinogenesis model, by abrogating oxidative stress and improving the redox status of colonic cells.
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Rehman, Atiq-ur,Rafique, Shahid,Ali, Amanat,Munir, M. Asian Australasian Association of Animal Productio 1990 Animal Bioscience Vol.3 No.4
Twenty-four Harnai lambs 6 to 7 month old, weighing $16{\pm}2kg$ were used in a completely randomized design in growth and digestibility trials to study fourwing saltbush ratio supplemented with cotton seed cake. The animal were divided at random into three groups of 8 animals each. Three iso-nitrogenous (10.5% CP) experimental rations (1, 2 and 3) containing wheat straw + lucerne hay (24:76); fourwing saltbush (Atriplex canescens) + cotton seed cake (71:29); and wheat straw + cottonseed cake (41:59); respectively, were allotted to each group randomly. All the animals were taken out for grazing in a dormant native range for about 3 hours in the afternoon during the growth trial. The growth trial lasted for 8 weeks followed by a digestibility trial. At the end of 8 weeks lambs on ration 3 had gained significantly (p<0.10) more weight compared to those on rations 1 and 2 which maintained their body weight. The crude protein digestibility of the fourwing saltbush based ration was comparable with the other two treatments (71 vs 70 and 71%). However, the digestibility of dry matter (41%), acid detergent fibre (13%) and neutral detergent fibre (22%) of this ration was significantly lower (p<0.10) than the other two diets. The results suggest that lambs can be maintained on fourwing saltbush during winter without significant loss in body weight with 30% extra protein concentrate supplementation.
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