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        Gear fault diagnosis under variable conditions with intrinsic time-scale decomposition-singular value decomposition and support vector machine

        Zhanqiang Xing,Jianfeng Qu,Yi Chai,Qiu Tang,Yuming Zhou 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.2

        The gear vibration signal is nonlinear and non-stationary, gear fault diagnosis under variable conditions has always been unsatisfactory. To solve this problem, an intelligent fault diagnosis method based on Intrinsic time-scale decomposition (ITD)-Singular value decomposition (SVD) and Support vector machine (SVM) is proposed in this paper. The ITD method is adopted to decompose the vibration signal of gearbox into several Proper rotation components (PRCs). Subsequently, the singular value decomposition is proposed to obtain the singular value vectors of the proper rotation components and improve the robustness of feature extraction under variable conditions. Finally, the Support vector machine is applied to classify the fault type of gear. According to the experimental results, the performance of ITD-SVD exceeds those of the time-frequency analysis methods with EMD and WPT combined with SVD for feature extraction, and the classifier of SVM outperforms those for K-nearest neighbors (K-NN) and Back propagation (BP). Moreover, the proposed approach can accurately diagnose and identify different fault types of gear under variable conditions.

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        Overexpression of miR-191 Predicts Poor Prognosis and Promotes Proliferation and Invasion in Esophageal Squamous Cell Carcinoma

        Xiaotian Gao,Zeqing Song,Zhanqiang Xie,Zhigang Wang,Keluo Cheng,Ke Liang 연세대학교의과대학 2017 Yonsei medical journal Vol.58 No.6

        Purpose: Accumulating evidence has shown that dysregulation of microRNA-191 (miR-191) is closely associated with tumorigenesisand progression in a wide range of cancers. This study aimed to explore the potential role of miR-191 in esophageal squamous cell carcinoma (ESCC). Materials and Methods: miR-191 expression was assessed in 93 ESCC tissue specimens by real-time polymerase chain reaction, and survival analysis was performed via Kaplan-Meier and Cox regression analyses. 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide, plate colony-forming, BrdU, and Transwell assays were conducted to observe the effect of miR-191 on ESCC proliferation and invasion. Luciferase reporter and western blot assays were taken to identify target genes of miR-191. Results: miR-191 was overexpressed in 93 cases of ESCC, compared with adjacent normal tissues, and miR-191 expression was significantly related to differentiation, depth of invasion, TNM stage, lymph node metastasis, and distant metastasis of tumor. Kaplan-Meier and Cox regression analyses demonstrated that overexpression of miR-191 was an independent and significant predictorof ESCC prognosis. Both gain-of-function and loss-of-function experiments showed that miR-191 promoted ESCC cell proliferation and invasion activities in vitro. Early growth response 1 (EGR1), a tumor suppressor, was predicted as a direct target of miR-191. Luciferase reporter and western blot assays proved that miR-191 reduced EGR1 expression by directly binding its 3' untranslated region. Moreover, EGR1 knockdown by siRNA enhanced ESCC cell growth and invasion. Conclusion: Our findings provide specific biological roles of miR-191 in ESCC survival and progression. Targeting the novel miR-191/EGR1 axis represents a potential new therapeutic way to block ESCC development.

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        A Novel Rate-dependent Direct Inverse Preisach Model With Input Iteration for Hysteresis Compensation of Piezoelectric Actuators

        Yutong Sun,Haifeng Ma,Zhanqiang Liu,Yangmin Li,Zhenhua Xiong 제어·로봇·시스템학회 2024 International Journal of Control, Automation, and Vol.22 No.4

        This paper proposes the design and validation of a novel rate-dependent direct inverse Preisach model with input iteration (RDIPMII) dedicated to feedforward compensation of hysteresis nonlinearity in piezoelectricactuators (PEAs). Unlike existing similar works, the proposed RDIPMII avoids deriving the parameters of the inverse compensator from the hysteresis model, and could be directly employed as the inverse compensator. Furthermore, RDIPMII is capable of achieving rate-dependent inverse compensation while reducing the experimental burden in identifying models by the use of newly proposed data expression method (DEM). In addition, by integrating iterative learning control (ILC), RDIPMII accomplishes online input iteration to further suppress the hysteresis effect. The feasibility and efficiency of the presented scheme are demonstrated through experimental investigations conducted on a PEA.

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