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계란껍질 분말을 혼입한 시멘트 페이스트의 역학 특석 및 CO<sub>2</sub> 배출량 연구
진옥곤 ( Chen¸ Yukun ),이한승 ( Lee¸ Hanseung ) 한국건축시공학회 2021 한국건축시공학회 학술발표대회 논문집 Vol.21 No.2
This study investigated the use of different amounts of eggshell powder (ESP), namely 5%, 10%, and 15% by weight, as a substitute for Ordinary Portland Cement. The results show that its flowability and 28-day compressive strength. Meanwhile the carbon dioxide emission was though sustainable assessment analyzed It was concluded that ESP replacement level of around 5% provides the best performance to reduces environmental pollution.
Vitamin D Receptor BsmI Polymorphism and Colorectal Cancer Risk: an Updated Analysis
Yu, Kun,Yang, Jing,Jiang, Yan,Song, Run,Lu, Qing Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.12
Background: Previous studies have investigated the association between the vitamin D receptor (VDR) BsmI polymorphism and colorectal cancer (CRC) susceptibility, but the results were conflicting. The aim of this study is to quantitatively summarize the relationship between this polymorphism and CRC risk. Materials and Methods: Two investigators independently searched the Medline, Embase, China National Knowledge Infrastructure (CNKI) and Chinese Biomedicine databases for studies published before November 2013. Summary odds ratios (ORs) and 95% confidence intervals (95%CIs) for VDR BsmI polymorphism and CRC were calculated in a fixed-effects model (the Mantel-Haenszel method) and a random-effects model (the DerSimonian and Laird method) when appropriate. Results: This meta-analysis included 14 case-control studies, which included 10,822 CRC cases and 11,779 controls. Overall, the variant genotype (BB) of the BsmI was associated with a lower CRC risk when compared with the wild-type bb homozygote (OR=0.66, 95%CI: 0.49-0.88). Similarly, a decreased CRC risk was also found in the dominant and recessive models. When stratifying for ethnicity, source of controls, and study sample size, associations were observed among Caucasians, population-based studies and studies with large study sample size (>1000 subjects). Limiting the analysis to the studies within Hardy-Weinberg equilibrium, the results were persistent and robust. No publication bias was found in the present study. Conclusions: This updated meta-analysis suggests that the VDR BsmI polymorphism may be associated with a moderate protective effect against CRC.
Yukun Lv,Zekun Ge,Yunpeng Liu,Lei Zhu,Shaoke Wei 대한전기학회 2015 Journal of Electrical Engineering & Technology Vol.10 No.4
In order to study the effect of the high-altitude and dusty weather in northwest of China on the corona characteristics of transmission lines, a corona caged based experimental system with sandy and dusty flow condition is numerically investigated and designed. This system overcomes the difficulties caused by harsh environment and offers easy usage for off-site tests. The design parameters are mainly determined by the characteristics of strong sandstorm in northwest region and test requirements. By the comparison of numerical simulation of the particle diffusion in four programs with rectangular or circular air-duct, a practical technology, which introduces swirl to control the particle diffusion length, is obtained. Accordingly, the structure of round air-duct with swirl elbow in inlet and outlet of high level segment is selected as final program. Systems of control and measurement are designed at the same time. Field tuning results show that the test system could ensure the range of sandy and dusty coverage. The wind speed, sandy and dusty concentration could be controlled and meet the requirements of accuracy. The experimental system has many features, such as simple structure, easy to be assembled, disassembled, transported and operated, small space occupied.
MicroRNA-21 controls the development of osteoarthritis by targeting GDF-5 in chondrocytes
Yukun Zhang,Jie Jia 생화학분자생물학회 2014 Experimental and molecular medicine Vol.46 No.-
Osteoarthritis is a common cause of functional deterioration in older adults and is an immense burden on the aging population. Altered chondrogenesis is the most important pathophysiological process involved in the development of osteoarthritis. However, the molecular mechanism underlying the regulation of chondrogenesis in patients with osteoarthritis requires further elucidation, particularly with respect to the role of microRNAs. MiR-21 expression in cartilage specimens was examined in 10 patients with knee osteoarthritis and 10 traumatic amputees. The effect of miR-21 on chondrogenesis was also investigatedin a chondrocyte cell line. The effect of miR-21 on the expression of growth differentiation factor 5 (GDF-5) was further assessed by luciferase reporter assay and western blot. We found that endogenous miR-21 is upregulated in osteoarthritis patients, and overexpression of miR-21 could attenuate the process of chondrogenesis. Furthermore, we identified GDF-5 as the direct target of miR-21 during the regulation of chondrogenesis. Our data suggest that miR-21 has an important role in the pathogenesis of osteoarthritis and is a potential therapeutic target.
Yukun Shu,Xiaoli Ruan,Xisheng Zhan 제어·로봇·시스템학회 2023 International Journal of Control, Automation, and Vol.21 No.10
This article investigates the global O(t-ρ) synchronization problem for multiple fractional-order neural networks (MFNNs) with time delay. By utilizing the unique properties of fractional-order calculus, namely hereditary and infinite memory, a new design scheme of the event-triggered non-Laplacian coupling control strategy is proposed. Compared with the Laplacian coupling matrix, non-Laplacian coupling matrix nondiagonal elements can be arbitrary and row sums can be same nonzero constant. With the introduced rules, by using a Razumikhin-type method, some less conservative sufficient conditions are derived to assure the global O(t-ρ) synchronization of MFNNs with time delay. Furthermore, in order to prohibit Zeno behavior in the MFNNs with time delay, lower bounds of two consecutive events are also gathered. Finally, simulation results verify the validity of the analysis.
( Yukun Huang ),( Lu Liu ),( Linna Chen ),( Lin Zhou ),( Xia Xiong ),( Yongqiong Deng ) 대한피부과학회 2021 Annals of Dermatology Vol.33 No.6
Background: The gut microbial dysbiosis and gender differences in the pathogenesis of acne vulgaris have long been postulated respectively. However, there was no data about a genderrelated discrepancy in gut microbiota and microbial metabolism in acne. Objective: This study aimed at identifying the underlying gender-related difference in gut microbiota and metabolism in acne vulgaris. Methods: Fecal samples were collected from 43 acne patients and 43 age and gender-matched controls. Gut microbiota was analyzed by sequencing the V3-V4 region of 16SrDNA gene and microbial metabolites were quantitatively detected using gas chromatography time-of-flight mass spectrometry. Results: Compared with healthy controls, the men had a lower abundance of 18 microbes such as Butyricicoccus , Clostridium sensu stricto, Faecalibaculum, Bacillus , Lactococcus , Blautia, Clostridiales, Lachnospiracea incertae sedis, Ruminococcus at genus level. However, the female patients only showed increased Clostridium sensu stricto and declined Oscillibacter and Odoribacterin. Additionally, the disordered metabolism of fatty acids was identified in male patients, while the dysbiosis of amino acids metabolism in female ones. Conclusion: The disorder of gut microbiota and metabolism in acne vulgaris was genderspecific, which supported the potential role of gender difference in the pathogenesis of this disease.
Yukun Tao,Wenhu Tang 대한전기학회 2018 Journal of Electrical Engineering & Technology Vol.13 No.3
This paper proposes a virtual flux (VF) and positive-sequence power based control strategy to improve the performance of grid-interfaced three-phase voltage source converters against unbalanced and distorted grid conditions. By using a second-order generalized integrator (SOGI) based VF observer, the proposed strategy achieves an AC voltage sensorless and grid frequency adaptive control. Aiming to realize a balanced sinusoidal line current operation, the fundamental positive-sequence component based instantaneous power is utilized as the control variable. Moreover, the fundamental negative-sequence VF feedforward and the harmonic attenuation ability of a sequence component generator are employed to further enhance the unbalance regulation ability and the harmonic tolerance of line currents, respectively. Finally, the proposed scheme is completed by combining the foregoing two elements with a predictive direct power control (PDPC). In order to verify the feasibility and validity of the proposed SOGI-VFPDPC, the scenarios of unbalanced voltage dip, higher harmonic distortion and grid frequency deviation are investigated in simulation and experimental studies. The corresponding results demonstrate that the proposed strategy ensures a balanced sinusoidal line current operation with excellent steady-state and transient behaviors under general grid conditions.