호알칼리성 Bacillus sp. No. 4의 Cyclodextrin Glycosyltransferase에 의한 Glycosyl Sucrose의 생산과 저충치성 당으로서의 응용

손천배,유미경,김명희,문숙경 충남대학교부설 생명공학연구소 1992 생물공학연구지 Vol.2 No.-

Action of a cyclodextrin glycosyltransferase (CGTase) produce from alkalophilic Bacillus sp. No. 4 was studied in a solution containing starch and sucrose to prepare glycosyl sucrose syrup with good sweetness and antidecaying properties of teeth. In the initial stage of the reaction the CGTase produced cyclodextrin, however, the cyclodextrin disappeared and glycosyl sucrose was formed with the lapse of reaction time. The best proportion of sucrose to starch for prodution of glycosyl sucrose was about 1 : 1. The optimum pH and temperature of the coupling reaction was pH 6.0 and 60℃, respectively. Main composition of glycosyl sucrose syrup prepared with 20% starch and 20% sucrose was sucrose 18%, glucosyl sucrose (G_2F) 15.3% and amltosyl sucorse (G_3F) 11.3%. And glucose, maltose and maltotriose were produced very little. Smaller amounts of acid and insoluble glucan were formed in the syrup by Streptococcus mtans OMZ176 than in the sucrose. Therefore, the prepared glycosyl sucrose sucrose syrup is expected to prevent teeth from decaying.

λ-경쇄형 다발성 골수종 1예

박용관,김태원,장영,김진호,강정원,천영욱,박유환,정춘해 조선대학교 1995 The Medical Journal of Chosun University Vol.20 No.1

Multiple myeloma is a disease caused by neoplastic plasma cells that synthesize abnormal amouts of immunoglobulin or immunoglobulin fragments. Light chain myeloma are regarded as a separate category characterized by a more malignant clinical course. Light chain myelomas are said to grow fastest of all and are associated with more osteolytic lesions, more hypercalcemia, and a higher incidence of renal failure and amyloidsis than either the IgG, IgA varienties The authors experienced a case of patients with λ-light chain myeloma. A 43-year-old male patient admitted to our hospital with the chief complaint of both rib and lower back pain. The radiologic findings showed multiple pathologic fracture in ribs. osteolytic lesions in 2nd, 3rd cervical spineimmuture plasma cells. Serum electrophoresis showed normal finding. Urine electrophoresis evealed an M-spike. Urine immunoelectrophoress demonstrated λ-monoclonal protein. With the cycle of melphalan, prednisone and α-interferon chemotherapy improved of pain was observed. So we reported the case with brief review of previous literature.

피부 병변을 동반한 악성조직구증 1예

조은택,박용관,김진호,강정원,천영욱,전익섭,박유환,전춘해 조선대학교 1995 The Medical Journal of Chosun University Vol.20 No.1

Malignant histiocytosis, originally described in 1939 as histiocytic medullary reticulosis by Scott and Robb-Smith, is a rare histiocytic proliferative disorder that often shows an acute onset and used to progress to death within a few months. This disorder characterized clinically by fever, generalized weakness, lymphadenopathy and hepatosplenomegaly, and shows a variable range of pancytopenia. Extranodal involvement is common, with an incidence ranging from 50% to as high as 90%, skin involves8ment was noted in 10% to 15%. Typical skin lesions were mainly founded in extremity. i.e. erythematous papule and nodule occasionally become to necrosis and ulceration. We experienced one case of malignant histiocytosis in a 46-years-old female. The major clinical findings are fever, malaise, hepatosplenomegaly and erythematous skin lesion. In the laboratory study, pancytopenia is noted on the peripheral blood. And also aggregation of many atypical histiocytes were shown on skin and bone marrow biopsy. So we reported one related case with malignant histiocytosis as well as reviewing literature .

SENIORITY PAY , TURNOVER AND JOB TRAINING IN KOREA(JEL Classification : J41)

CHEON, BYUNG YOU 한국경제학회 1998 The Korean Economic Review Vol.14 No.1

Therapeutic effect of subconjunctival injection of bevacizumab in the treatment of corneal neovascularization

You, In-Cheon,Kang, In-Seong,Lee, Seung-Hyun,Yoon, Kyung-Chul Blackwell Publishing Ltd 2009 Acta ophthalmologica Vol.87 No.6

<P>Abstract.</P><P>Purpose: </P><P>To investigate the efficacy of subconjunctival injection of bevacizumab in the treatment of patients with corneal neovascularization.</P><P>Methods: </P><P>Twenty-nine eyes of 29 patients with corneal neovascularization were treated with subconjunctival injection [1.25 mg/0.05 ml (seven eyes), 2.5 mg/0.1 ml (15 eyes) and 5.0 mg/0.2 ml (seven eyes)] of bevacizumab. Best-corrected visual acuity, intraocular pressure and area of corneal neovascularization were measured before injection and at 1 week, 1 month and 3 months after treatment.</P><P>Results: </P><P>At 1 week, the mean neovascularized corneal area decreased significantly to 85.5 ± 18.0% (<I>p</I> =<I> </I>0.01) in the eyes treated with 2.5 mg bevacizumab and to 73.1 ± 23.4% (<I>p</I> =<I> </I>0.02) in the eyes treated with 5.0 mg bevacizumab. At 3 months, the mean neovascularized corneal area was 93.6 ± 10.6% (<I>p</I> =<I> </I>0.10 compared to baseline; <I>p</I> <<I> </I>0.01 compared to 1 week) in the eyes treated with 2.5 mg bevacizumab and 83.3 ± 25.8% (<I>p</I> =<I> </I>0.03 compared to baseline; <I>p</I> =<I> </I>0.02 compared to 1 week) in the eyes treated with 5.0 mg bevacizumab. However, there were no significant changes in the areas of the eyes injected with 1.25 mg bevacizumab.</P><P>Conclusion: </P><P>Subconjunctival injection of bevacizumab can partially reduce corneal neovascularization in the short term, and the efficacy of this treatment correlates with the injection dose.</P>

A Case Report of Herpes Zoster Ophthalmicus and Meningitis After COVID-19 Vaccination

You In-Cheon,Ahn Min,Cho Nam-Chun 대한의학회 2022 Journal of Korean medical science Vol.37 No.20

There are several reports that herpes zoster characterized by reactivation of varicella zoster virus (VZV) following coronavirus disease 2019 (COVID-19) vaccines can occur. Herein, we report VZV meningitis, herpes zoster ophthalmicus (HZO), and late neurotrophic keratitis after receiving a second dose of messenger RNA (mRNA) COVID-19 vaccine. A 74-year-old man developed a vesicular skin rash on the forehead, scalp, nose, and left upper eyelid with a severe headache. Five days earlier, he received a second dose of the BNT162b2 mRNA vaccine on his left arm. Ocular examination revealed conjunctival hyperemia and pseudodendrite in the peripheral cornea. VZV was detected in the cerebrospinal fluid using polymerase chain reaction. The patient was diagnosed with HZO and meningitis. The patient was treated with intravenous acyclovir and topical acyclovir ointment and levofloxacin 1.5% eye drops. One month later, he developed a central epithelial defect with a rolled margin, typical of a neurotrophic ulcer. Treatment with a therapeutic contact lens and a combination of topical recombinant human epithelial growth factor and ofloxacin ointment was initiated. At six months after vaccination, the slit-lamp examination findings were stable with a mild corneal superficial stromal haze.

임금 불평등 변화의 요인분해: 2006-2015년

정준호 ( Cheon Byung-you ),전병유 ( Jeong Jun-ho ),장지연 ( Chang Jiyeun ) 한국산업노동학회 2017 산업노동연구 Vol.23 No.2

이 글에서는 2000년대 중반 이후 한국의 임금불평등을 지니계수의 변화와 이를 초래한 요인들의 기여도를 분석하였다. 자료와 임금 지표에 따라 추세가 달라지지만, 주당 35시간 미만 일하는 파트타임의 증가로 전체근로자 임금총액의 지니계수는 증가하는 추세를 보여주는 반면, 시간당임금 지니계수와 풀타임근로자의 임금총액 지니계수는 하락하는 추세를 나타냈다. 파트타임 증가가 임금총액 기준의 불평등은 높였지만, 파트타임의 시간당임금 증가는 시간당임금 기준의 불평등을 낮추었다. 풀타임 노동자만을 대상으로, 지니계수 감소 요인을 분해한 결과, 불평등 감소에 절대적으로 기여가 큰 요인은 근속, 경력, 직종 등의 변수였고, 고용형태 변수는 불평등 감소에 미미하게 기여하는 것으로, 사업체 규모 변수는 불평등을 오히려 높이는 것으로 나타났다. 업종이나 연령, 교육 등의 변수는 불평등 변화에 유의미한 크기의 기여를 하지 못한 것으로 분석되었다. 여기에는 장기근속과 관리전문직종에 대한 임금프리미엄의 감소와 대규모사업체의 임금프리미엄 증가 등이 작용한 것으로 분석되었다. This paper analyzes the changes in wage inequality and its contributing factors since the mid-2000s. Although trends vary by data and wage indices, the Gini coefficient of the total wage of all workers shows an increasing trend due to the part-time increase of less than 35 hours per week, while the wage Gini coefficient of hourly wages and the total wage Gini coefficient of full-time workers showed a declining trend. Part-time increases have increased inequality based on total wages, but part-time hourly wage increases can be considered to have reduced hourly wage inequality. Therefore, as a result of decomposing the factor of Gini coefficient reduction only for full-time workers, factors that contributed absolutely to inequality reduction were variables such as job tenure, career, and occupation, and employment type variable has little effects, and the establishment size variable deepens inequality. The variables such as industry, age, and education did not contribute significantly to the inequality change. This is attributed to the decline in wage premiums for job tenure and management and professional jobs and the increase in wage premiums for large-scale businesses.

멀티미디어 디자인에서 사용자 인터페이스 그래픽 메타포 유형에 관한 연구

류시천(You Si-cheon) 한국디자인학회 2000 디자인학연구 Vol.- No.39

THE MATERIAL BALANCE OF PCDDs/DFs IN THE LEACHATE LANDFILL TREATMENT PROCESS OF MUNICIPAL SOLID WASTE LANDFILL

( Jae-cheon You ),( Chang-han Joo ),( Dong-hoon Lee ),( Jong-choul Won ),( Bong-hyun Park ) 한국폐기물자원순환학회 2002 APLAS Vol.2002 No.1

This study is to survey the material flow of PCDDs/DFs in the leachate treatment process of the sanitary landfill for municipal solid wastes(MSW) which are mainly consisted of about 60% of household and commercial wastes, about 20% of construction & demolition wastes, about below 10% of sewage & water treatment sludges, and etc. The maximum quantity of collected leachate from landfill was 6,700㎥ per day at that time. The source of PCDDs/DFs in the collected leachate from landfill may be originated from wastes itself. Leachate treatment process is consisted of the biological denitrification/nitrification, coagulation and precipitation and fenton process. Samples obtained from the inner of each unit process were separated into two as filtered part and filtrate part through filtering by GF/B(1.0㎛). Each separated sample was analyzed according to 1613 EPA Method for PCDDs/DFs to calculate mass flow of PCDDs/DFs about input and output of the each unit process. The input amount of PCDDs/DFs calculated 0.057mg- TEQ/day entered into biological treatment process from landfill and the output of that was 0.140mg-TEQ/day. In the next process of coagulation and precipitation 0.0068mg-TEQ/day went out in the form of sludge cake and 0.0032mg-TEQ/day flowed into the next fenton process. In that process 0.0048mg-TEQ/day went out in the form of sludge cake. As a result 99.94% of input PCDDs/DFs in the collected leachate was discharged into the environment as sludge cake (returned to landfill here) and 0.06% of that was discharged into the water system as the effluent water. The concentration of sludge generated from biological and chemical coagulation process was in the range of 9.853 ~ 18.880 pg-TEQ/g. Annual emission amount of PCDDs/DFs was 24.462mg-TEQ in the landfill.

요소소득분배가 가구소득 불평등에 미치는 영향에 관한 연구

전병유(Cheon Byung You) 한국경제발전학회 2015 經濟發展硏究 Vol.21 No.4

최근 거시적인 노동소득분배율 하락과 미시적인 가구소득 불평등 증가가 동시에 나타나면서, 요소소득분배율의 변화가 가구소득 불평등에 미치는 효과에 대한 관심이 증가하고 있다. 요소소득분배율이 가구소득불평등에 미치는 영향은 요소소득의 집중도, 그리고 요소소득의 상대적 비중과 총소득과의 상관관계에 따라 좌우된다. 우리나라의 국민계정 상의 요소소득 분배 구조를 가계조사 자료와 비교하고, 가구소득에서 요소소득분배율의 변화가 가구소득 불평등도에 기여하는 정도를 추정했다. 가계조사에서는 재산소득의 비중 자체가 작고, 재산소득 비중과 전체 시장소득과의 관계가 L자형이나 U자 형으로 상관관계가 높지 않은 것으로 나타났다. 이는 요소소득분배율의 변화가 가구소득불평등에 미치는 영향이 크지 않을 수 있다는 점을 시사한다. 다만, 분석대상을 가구주가 취업자인 경우로 한정할 경우, 재산소득 비중이 작아질수록 가구소득 불평등도는 낮아진다는 점이 확인되었다. 가계조사에서 재산소득의 과소보고와 고소득층의 과소대표 문제를 고려하면 실제 효과는 더 커질 수 있다.(JEL: D3, R2). This paper is to analyse the effects of factor distribution on household income inequality. The statistical data shows that declines in labor's share have positive correlation with increasing household income inequalities. The effects of factor distribution on income inequality depend on concentration of factor income and the correlation between share of factor income and total income. This paper compares factor income distribution of national account with the one in the household survey, and estimate the effects of changes in factor distribution on household income inequalities. The the share of capital income in household survey is so low, and the relationship between its share and total income has L or U-shaped form. It implies that the effects would not be so large. If the household income is to be decomposed by its income sources for the household with househead holding job, however, the lower capital income's share lead to lower income inequality. This effects will be larger if we could consider the relative lower reporting of capital income and lower representative of those with higher share of capital income in the household income survey.