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Vaclav ?e?ulka,Pavel Straka 한국자기학회 2016 Journal of Magnetics Vol.21 No.3
The article presents the results and findings obtained through the assembly of opposing linear Halbach arrays from two magnet layers using large magnetic blocks from permanent NdFeB magnets, especially concerning the distribution of magnetic induction in an air gap. The use of these large blocks has led to a significant expansion of the area of magnetic field with a substantially higher value of magnetic induction in comparison with similar linear Halbach arrays composed of small magnets. The paper also discusses the determined dependences of magnetic induction on the parameters of the x, y, z coordinate system and indicates the possibilities of achieving an even stronger magnetic field in a larger volume of an air gap for application for instance in equipment for magnetic separation of raw materials, in instrument technologies and in other areas.
Vaclav ?e?ulka,Pavel Straka 한국자기학회 2018 Journal of Magnetics Vol.23 No.2
The article presents the results of the experimental implementation of separate and opposing linear structures of different sizes using NdFeB permanent magnets. It focuses on the distribution of the resulting magnetic induction. For both separate and opposing structures, composed of two layers of magnets, the magnetic induction attained was much more affected by changes in the width of the central magnet than by the increasing width of side magnets. When the width of the central magnet in either of the two opposing double-layer Halbach structures was increased approximately three times, the area of the uniform magnetic field attained in the middle of a 20-mm-wide air gap was roughly three times bigger with only ca 7% lower induction in comparison with opposing Halbach structures of optimized dimensions. These make it possible to generate the maximum magnetic field in the middle of the air gap, but only in a narrow band.
Vaclav ?e?ulka,Pavel Straka 한국자기학회 2017 Journal of Magnetics Vol.22 No.2
The article presents the principle of a relatively small device that makes it possible to generate a strong magnetic field in an air gap without electrical energy consumption. It describes the implemented design of this device, the method of the assembly of opposing linear arrays from two NdFeB magnet layers, its advantages, the possible ways of increasing the parameters further and its application in various areas.
Vaclav Vetvicka,Jana Vetvickova 한국식품영양과학회 2016 Journal of medicinal food Vol.19 No.12
Thymus species are popular spices and contain volatile oils as main chemical constituents. Recently, plant-derived essential oils are gaining significant attention due to their significant biological activities. Seven different thymus-derived essential oils were compared in our study. First, we focused on their chemical composition, which was followed up by testing their effects on phagocytosis, cytokine production, chemotaxis, edema inhibition, and liver protection. We found limited biological activities among tested oils, with no correlation between composition and biological effects. Similarly, no oils were effective in every reaction. Based on our data, the tested biological use of these essential oils is questionable.
Vaclav Vetvicka,Aruna Vashishta,Marta Fuentes,Roberto Baigorri,Jose M. Garcia-Mina,Jean-Claude Yvin 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.7
Despite the rather common presence of humic acid (HA), our full knowledge of its biological effect is still lacking. In this article, we first performed a physicochemical characterization of several HAs, and next, we evaluated their ability to affect interleukin-2 secretion, antibody secretion, wound healing (an in vitro model using HaCaT cells), cancer growth (the Lewis lung carcinoma model), and protection against hepatotoxicity. In all tested reactions, HA showed significant stimulation on immune reactions, including suppression of cancer growth and inhibition of lipopolysaccharideinduced hepatotoxicity. These effects were dependent on its chemical properties. The pleiotropic effects of HA observed in this article suggest the possible role of these compounds in human nutrition.
Glucan and Humic Acid: Synergistic Effects on the Immune System
Vaclav Vetvicka,Roberto Baigorri,Angel M. Zamarreno,Jose M. Garcia-Mina,Jean-Claude Yvin 한국식품영양과학회 2010 Journal of medicinal food Vol.13 No.4
Humic acids are compounds resulting from decomposition of organic matter. Despite their common presence, our knowledge of their biological effects is limited, and current findings are controversial. We decided to evaluate the immunological effects of two different types of humic acids, differing in source and biochemical characteristics. Using both components either alone or in combination with the well-established yeast-derived immunomodulator glucan, we measured their effects on both the cellular (phagocytosis and tumor suppression) and humoral (antibody production and cytokine secretion) branches of immune reactions. In summary, our results suggest that humic acids are biologically active immunodulators affecting both the humoral and cellular branches of immune reactions. In addition, the two humic acids studied here are working in synergy in stimulation of the immune reaction, supporting further studies of these natural immunomodulators.
Immunological Effects of Yeast- and Mushroom-Derived β-Glucans
Vaclav Vetvicka,Aruna Vashishta,Sujata Saraswat-Ohri,Jana Vetvickova 한국식품영양과학회 2008 Journal of medicinal food Vol.11 No.4
Glucans have a long history as nonspecific biological modulators. We compared the effects of three different glucans on immune reactions. Using two different administrations (intraperitoneal and oral) and two different animal models, we showed that yeast-derived Betamune™ (Biorigin, São Paulo, Brazil) caused significant stimulation of phagocytic activity as well as potentiation of synthesis and release of interleukin (IL)-1, IL-2, IL-4, IL-6, IL-8, IL-13, and tumor necrosis factor-α. In addition, Betamune inhibited growth of tumor cells in vivo and affected expression of several important genes in breast cancer cells. Compared to adult mice, young animals showed different sensitivity to glucan action.
β(1-3)-D-glucan affects adipogenesis, wound healing and inflammation
Vaclav Vetvicka,Jana Vetvickova 경희대학교 융합한의과학연구소 2011 Oriental Pharmacy and Experimental Medicine Vol.11 No.3
Numerous types of β(1-3)-D-glucans have been isolated from almost every species of yeast, grain, and fungi. These products have been extensively studied for their immunological and pharmacological effects. In this paper we evaluated the possibility whether individual β(1-3)-D-glucans will have an activity in less studied areas such as adipogenesis and inflammation. Our results showed that of the tested β(1-3)-D-glucans, yeast-derived insoluble Glucan #300, strongly inhibited adipogenic differentiation,supported wound healing and significantly lowered skin irritation. The remaining β(1-3)-D-glucans were significantly less active. Taken together, our study showed that with respect to natural β(1-3)-D-glucans, there is a clear yes-or-no effect suggesting that highly purified and highly active β(1-3)-D-glucans will have pleiotropic biological impact, whereas poorly isolated and/or less active β(1-3)-D-glucans will have only mediocre properties.
Numerals in Mongolic and Tungusic languages with notes to code-switching
( Vaclav Blazek ),( Michal Schwarz ) 한국알타이학회 2016 알타이학보 Vol.0 No.26
Numerals represent a specified semantic field, where deep archaisms can appear besides recent loans in various language groups. The comparative method allows us to stratify different layers in lexicon: 1. Substrata; 2. Inherited lexicon; 3. Adstrata. 4. Superstrata. Socio-linguistics mentions situations, when forms of the same meaning, but of various origins, are used in parallel, one alongside another. In the present contribution we study the numerals in Mongolic and Tungusic languages, including analysis of their etymologies, identification of interferences and description of their use in code-switching. In the past this phenomenon could have played a role in the process of adaptation of foreign forms, including numerals, in the same way as in the present. The carefully analyzed stratigraphy of lexicon allows us to identify which of its parts are inherited, which borrowed, from which source and in which period. These results can be used for the determination of original homeland, trajectories of migrations and positions of neighbors.