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김세련,김종욱 관동대학교 의과대학 의과학연구소 2005 關東醫大學術誌 Vol.9 No.1
Polycystic ovary syndrome (PCOS) is a heterogenous and a common disorder in the women of reproductive age. In these women the ovary seems to be the primary site of endocrine abnormalities, especially hyperandrogenism. Insulin resistance and hyperinsulinism, the main causes of PCOS, augment hyperandrogenism. There are evidences for underlying genetic causes for PCOS and several candidate genes are suggested. But a lot of thing in genetics still remain to be elucidated. The pathophysiology of PCOS appears to be multifactorial and polygenic and adverse health consequences such as cardiovascular disease, diabetes mellitus, and endometrial cancer are related with PCOS. So, treatment methods should be multiple and individualized.
Ricketts 분석법에 의한 혼합치열기 정상교합 아동의 두부방사선계측학적 평가에 대한 연구
한세현,이상민,정태련 大韓小兒齒科學會 1999 大韓小兒齒科學會誌 Vol.26 No.2
부정교합의 진단과 치료를 위해서는 두 개 및 안면부의 형태와 성장 양상에 대한 지식이 필수적이다. 그러나 소아치과 영역에서 필요한 혼합치열기 아동에 대한 연구는 성인의 그것에 비하여 많지 않음에 저자는 혼합치열기 정상교합 아동의 두부방사선학적 표준치를 얻고자 건치아동 선발대회의 후보중 보존적, 보철적, 교정적, 성형외과적 치료경험이 없고 연구모형 상에서 비교적 교합이 양호하며 안모 및 전신 발육 상태가 정상으로 생각되는 아동 102명(남자 48명, 여자 54명)을 선정하여 측모 두부방사선규격사진을 촬영한 후, Ricketts 분석법에 의해 분석하여 다음과 같은 결론을 얻었다. 1. 전두개저 길이, 후안면고경, 하악체의 길이를 나타내는 항목에서 남자가 여자보다 유의하게 큰 값을 나타내었고(p<0.05), Porion은 남자가 여자에 비해 후방위치하고 있었다(p<0.01) 2. 안면의 깊이를 통해서 본 Pogonion은 남자가 더 전방위치하고 있었고(p<0.05), 하악하연평면각은 남자에서보다 여자에서 유의하게 컸으며(p<0.01), FH 평면에 대해 남자의 상악중절치가 여자에 비해 유의하게 전방으로 경사져 있었다.(p<0.05) 3. 연령에 따라 유의하게 변하는 항목은 전두개저 길이, 상악대구치의 위치(p<0.01), 하악골체의 길이(p<0.05)였다. 4. 상악골의 고경, 안면의 깊이, 하악하연평면각, 상악돌출도등에서도 연령에 따른 변화는 보였지만 유의한 차이는 없었다.(p>0.05) IN order to define a current set of Korean children norm with mixed dentition, following study was done. The subjects were 102 healthy dentition contestants(48boys, 54girls). Standardized lateral head roentgenograms were taken, and Ricketts analysis was done. Results were as follows: 1. Length of anterior cranial base, posterior facial height, corpus length were longer in male than in female(p<0.05), and Porion was located posteriorly in male than in female(p<0.01). 2. Through facial depth, Pogonion of male was more forwardly positioned(p<0.05), mandible was significantly steeper in female, and maxillary anterior teeth were significantly tipped forward in male(p<0.05) 3. Variables such as length of anterior cranial base, upper molar position(p<0.01) and corpus length(p<0.05) were significantly changed by age. 4. Maxillary height, facial depth, mandibular plane angle, convexity were changed by age, but not significantly(p>0.05)
김세련(Kim, Se-Ryun) 대한일어일문학회 2017 일어일문학 Vol.75 No.-
The aim of this paper is to examine how the tasks for the learner studying seven kinds of textbook are handled to realize learner-centered teaching -learning activity and the most significant part is culture education under the current curriculum, especially the Korean-Japanese tasks for understanding different culture. Analysis target is the current seven kinds of high school text book 1. I investigated three domains ; first, cultural contents are covered independently, second, cultural contents are specified in learning objective, third, the content of the tasks and types are well organized. Analysis result shows that (1) there is a culture introduction column in the current seven kinds of high school text book apart from language function. (2) six kinds of textbooks consist of language function and culture except E textbook, which suggest “learning objective” with 84.5% on average. It reveals that such a result has greatly improved compared to Kim Se Ryun(2013)"s rate of goal suggestion that was 57% in 2007 revised textbook. (3) the single tasks and comparative tasks coexist and the rate of Korean-Japanese comparative tasks 67.1%, life culture area 63.8%, tradition and pop culture area 36.2%. Kim Se Ryun(2013)"s 2007 revised textbook leaned to life culture area 5.9% while the small deviation is in the current textbook. I also found that the way to suggest the tasks varied according to textbooks and every unit. (4) the way to suggest the tasks are ‘~let"s investigate’, ‘~let"s compare’, ‘~let’s research and present’, which contribute to develop learner"s independent and comprehensive judgement in the task-centered learning. This result seems to reflect learner-centered discussion rather than teacher-centered knowledge delivery. However, the lack of specified experiental activity is unfortunate. I think the most important part in the class is the textbook, which should be well organized in the domain of learning objective and the tasks under the current curriculum. In addition to, in the light of mutual of cultural education, the higher tasks should be established to attract learner"s motive and so many ways must be invented to meet learner"s needs. I expect that this research will be great helpful in developing future textbook.
( Se Ryun Kwon ) 한국어병학회 2012 한국어병학회지 Vol.25 No.3
Vibrio vulnificus ghosts (VVG) were generated using a mobilizable vector including a thermosensitive expression cassette by conjugation. The vaccine potential of VVG was investigated in mouse. Mice immunized with VVG showed significantly higher antibody titer than those with formalin-killed V. vulnificus. The present study supports the conceptive usefulness of bacterial ghosts as vaccine candidates.
Hepatic Steatosis Is a Significant Factor for Breast Cancer Recurrence after Curative Surgery
( Se Ryun Bae ),( Young-sun Lee ),( Su Min Bang ),( Yoon Seok Lee ),( Ji Hoon Kim ),( Sun Young Yim ),( Young Kul Jung ),( Yeon Seok Seo ),( Hyung Joon Yim ),( Jong Eun Yeon ),( Soon Ho Um ),( Kwan So 대한간학회 2021 춘·추계 학술대회 (KASL) Vol.2021 No.1
Kwon, Se Ryun,Kang, Yue Jai,Lee, Dong Jin,Lee, Eun Hye,Nam, Yoon Kwon,Kim, Sung Koo,Kim, Ki Hong Springer-Verlag 2009 Molecular biotechnology Vol.42 No.2
<P>Vibrio anguillarum ghosts (VAG) were generated, for the first time, using a conjugation vector containing a ghost bacteria inducing cassette, pRK-lambdaP(R)-cI-Elysis, in which the expression of PhiX174 lysis gene E was controlled by the P ( R )/cI regulatory system of lambda phage. By scanning electron microscopy, holes ranging 80-200 nm in diameter were observed in the VAG. To avoid the presence of bacterial genomic DNA and an antibiotic resistance gene in the final VAG product, we constructed a new dual vector, pRK-lambdaP(R)-cI-E-SNA, containing the E-mediated lysis cassette and the staphylococcal nuclease A (SNA)-mediated DNA degradation cassette, and generated safety-enhanced VAG for use as a fish vaccine.</P>