Ki-1 임파종 1 예

김용진,김경재,박재복,이지현,안기성,강민모,최석문,황기석 대한내과학회 1993 대한내과학회지 Vol.45 No.4

A 60-year-old man was admitted to our hospital complaining of fever with chillness and anarexia for 12 weeks. Physical examination revealed supraclavicular lymphadenopathy and left inguinal lymphadenopathy. Abdominal CT scan showed the evidence of maked lymphadenopathy on retraperitoneal, external iliac, obturator, left inguinal, and celiac lymph nodes. A pathologic diagnosis of Ki-1(+) lymphoma was made by the biopsed supraclavicular lymph node because the node consisted of large cells with pleomorphic nuclei, scanty cytoplasm, large basophilic nucleoli, atypical vacuoli and large cells were positive for leukocyte common antigen, Ber-H2, marker, and B-cell marker.

The Conjugated Double Bond of Coniferyl Aldehyde Is Essential for Heat Shock Factor 1 Mediated Cytotoprotection

Choi, Seul-Ki,Mun, Gil-Im,Choi, Eun,Kim, Seo-Young,Kwon, Youngjoo,Na, Younghwa,Lee, Yun-Sil American Society of Pharmacognosy 2017 Journal of natural products Vol.80 No.8

<P>Coniferyl aldehyde (1) is previously reported as a potent inducer of heat shock factor 1 (HSF1). Here, we further examined the active pharmacophore of 1 for activation of HSF1 using the derivatives coniferyl alcohol (2), 4-hydroxy-3-methoxyphenylpropanal (3), and 4-hydroxy-3-methoxyphenylpropanol (4). Both 1 and 2 resulted in increased survival days after a lethal radiation (IR) dose. The decrease in bone marrow (BM) cellularity and Ki67-positive BM cells by IR was also significantly restored by 1 or 2 in mice. These results suggested that the vinyl moiety of 1 and 2 is necessary for inducing HSF1, which may be useful for developing small molecules for cytoprotection of normal cells against damage by cytotoxic drugs and radiation.</P>

Therapeutic Effects of Recombinant Human Epidermal Growth Factor (rhEGF) in a Murine Model of Concurrent Chemo- and Radiotherapy-Induced Oral Mucositis

RYU, Seung-Hee,KANG, Ki Mun,MOON, Soo Young,CHAI, Gyu Young,HONG, Joon Pio,CHO, Kyoung-Oh,KANG, Mun-Il,CHOI, Eun Kyung,LEE, Sang-wook Journal of Radiation Research Editorial Committee 2010 JOURNAL OF RADIATION RESEARCH Vol.51 No.5

<P>Concurrent chemotherapy with radiotherapy (CCRT) has been applied for the treatment of advanced stage of head and neck cancer patients. However CCRT is associated with several complications including mucositis, dermatitis, stomatitis, etc. This study was conducted to evaluate the therapeutic effect of systemically administrated recombinant human epidermal growth factor (rhEGF) in CCRT-induced oral mucositis in a mouse model. Oral mucositis was induced in male BALB/c mice through combination treatment with cisplatin (11 mg/kg, i.p.) and irradiation (17 Gy) of the head and neck area. rhEGF (1.0 mg/kg/day for consecutive 3 days) was administered systemically, and the therapeutic effect was determined by histological evaluation of the oral mucosa. To elucidate optimal dose of rhEGF on CCRT-induced mucositis, various concentrations (0.04–3 mg/kg) of rhEGF were injected for 3 days. Systemic rhEGF administration accelerated the recovery of body weight. Histologically, rhEGF-treated mice showed significantly increased epithelial cell layer thickness, basal cell number, and expression of Ki-67 compared to control mice. Most effective dose was 1 mg/kg among other doses tested. Systemic administration of 1 mg/kg of rhEGF reduces the severity of oral mucositis induced by CCRT in a mouse model, suggesting that rhEGF can be used for treating CCRT-induced mucositis during the cancer treatment.</P>

양 족부 열감을 호소하는 하지불안증후군 환자 치험 1례

김경묵,서원주,김수빈,정우상,문상관,권승원,조기호,Kim, Gyeong-muk,Suh, Won-joo,Kim, Su-bin,Jung, Woo-sang,Mun, Sang-kwan,Kwon, Seung-won,Cho, Ki-ho 대한한방내과학회 2018 大韓韓方內科學會誌 Vol.39 No.2

Objectives: The purpose of this study is to evaluate the effectiveness of electroacupuncture on heat sensation of the feet of a 61-year-old female patient with restless leg syndrome. Methods: Electroacupuncture was performed at four acupoints (KI3 (太谿), KI6 (照海), LR3 (太衝), LR2 (行間)) selected to reduce heat sensation in both feet. The patient's symptoms were assessed using the VAS (Visual Analogue Scale), the SF-MPQ (short-form McGill Pain Questionnaire), and the IRLS (International Restless Legs Scale). The treatment was performed from April 20, 2010 to April 24, 2010. Results: During five sessions of electroacupuncture treatments, the VAS, SF-MPQ, and IRLS scores improved throughout the treatment period and afterwards. Conclusions: The results suggest that electroacupuncture at KI3(太谿), KI6(照海), LR3(太衝), LR2(行間) can be effective for reducing hot flush in both feet.

정신과 입원환자의 병원이탈에 대한 고찰

기문상,박상학,김명규 大韓神經精神醫學會 1996 신경정신의학 Vol.35 No.2

This study was a survey of all available hospital records pertaining to the 300 elopers of psychiatric inpatients admitted at Naju National Mental Hospital during the years between 1991-1993. The findings were compared with randomly selected control group of 300 inpatients who admitted during the same period. This study was designed to evaluate the demographic data and clinical characteristics, motivations, and results of elopement in these patients. Results were as follows : 1) During 3 years, 308 of 4670 inpatients(6.5%) committed elopememt. 2) Most of them were involuntarily admitted young male patients and they were likely to be unmarried, unemployed, and high-school graduated compared to control group. Their socioeconomic status were relatively low. 3) While the control group was mainly diagnosed as undifferentiated schizophrenia, more of elopers was diagnosed as paranoid schizophrenia. 4) Clinically, elopers had chronic course of illness, frequent and long-term hospitalization, and previous history of elopement than control group. 5) Patients in open wards showed more frequent elopement behavior than those in closed wards. They were likely to elope during the strolling. Many attempted to elope on Thursday when the family members visited them. 6) Most of the elopers were safely returned to the hospital and the management was simple interview without restraint. Many of families were not unconcerned about the patient's elopement. 7) Elopement group were characterized by their severe psychotic symptoms(hallucination, delusion). poor relationship with treatment teams, and cold familial concerns. It was suggested that the patient's intrapsychic factor(42.8%) was the most important factor in determining the elopement.

PID제어에 의한 單相 昇·降壓 整流器의 입력전류 특성에 관한 연구

徐基永,李壽欽,柳在葉,文相弼,李來一 경남대학교 신소재연구소 1999 論文集 Vol.11 No.-

Distortion Minimized of Input Current for Single-Phase Buck-Boost Rectifier is studied in the paper. To sinusoidal waveform the input current with a near-unity power factor over a wide variety of operating conditions, the output capacitor is operated with voltage reversibility for the supply by arranging the auxiliary diode and power switching device. Then the output voltage is superposed on the input voltage during on time duration of power switching devices in order to minimize the input current distortion caused by the small input voltage when changing the polarity. The tested setup, using two insulated-gate bipolar transistors(IGBT) and a microcomputer, is implemented and IGBT are switched with 20[kHz]. which is out of the audible band. Moreover a rigorous state-space analysis is introduced to predict the operation of the rectifier. The experimental and simulated results confirm that the input current can be sinusoidal waveform with a near-unity power factor and a satisfactory output voltage regulation can be achieved.

3相 4線式 配電系統의 高調波 障害對策에 關한 硏究

姜錤文,柳喆魯,朴正淳 全北大學校 1984 論文集 Vol.26 No.-

The third harmonic current contain much at the poltransformer exciting current of 22.9KV-Y 3-phase 4wire distribution system, therefore, that misoperated groundfault protective relay and overheated main transformer. magnitude of this higher harmonic current keeps under restrict at unbalance, but that presented increase phenomenon due to electro static capacity of cable etc. We install small AC filter on the ground fault relay to prevent this misoperation. In this paper, I deal with higher harmoniㅊs occurrence phenomenon, harmonic analysis method of distribution system circuit and counter-measure of disturbance by harmonic of protection relay.

학교체육 경영 활성화를 규정하는 조직풍토요인의 분석 : In the Case of the Managerial Organization for School Physical Education

원기승,문행자,최경범 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.2

This paper refered to the managerial organization for school physical education. But reports of this type of study have apparently not been published to date. Then in this paper it was indicated that the managerial organization should be discussed from three view points; (1) correlation between the school organization and managerial organization for physical education. (2) contingency theory. (3) motivational approach. The purposes of this paper. therefore, were to clarify the structure of the organizational climate and to analysis the relation between the organizational climate and the effectiveness of managerial organization. The survey was conducted at 7 primary school and 6 junior high school by questionnaire, and the subjects were 312 teachers. The summary of the results were: 1) The organizational climate of a school was consisted of six clements as follow: Maintenance, Cooperation, Task Achievement Job efficiency, Disengagement. Hindrance. These elements were integrated two dimensions that were HUMA-SYSTEM and TECHNICAL-SYSTEM. 2) The correlation between the organizational climate and Integration-Latency function of the managerial organization was significant high. Especially the organizational identification of the managerial organization was significant high. Especially the organizational identification which was one of the effectiveness variables was influenced most strongly by HUMAN and TECHNICAL-SYSTEM dimensions. 3) The positive attitude toward physical education services of teachers created innovation of management for physical education.

外國人勤勞者 雇傭許可制 導入에 대한 妥當性 檢討

高準基,鄭文盛 군산대학교 지역개발연구소 1995 地域開發硏究 Vol.7 No.-

體型別 Harvard Step Test後 血液有形成分의 變化

閔昌基,金文根 忠南大學校體育科學硏究所 1983 體育科學硏究誌 Vol.1 No.1

The purpose of this study was to see the change of the formed elements of blood according to the Somatotypes after the Harvard step test. Six male students of D middle school in Dae ton were served as subjects. They were classified into Endomorphy, Mesomorphy, and Ectomorphy by Sheldon’s anthropometric method. Being based on before and after Harvard step test for 5 minutes, the F ratio of change of the formed elements of blood according to the Somatotype groups obtained the Conclusions as following; 1. The formed elements of blood according to Somatotypes in normal state had no remarkable difference. 2. After Harvard step test, each of the Somatotype group marked increase of the formed elements of blood. 3. After Harvard step test, Mesomorphy was lower than Endomorphy and Ectomorphy in concentration rate of the formed elements of blood. 4. In Hemoglobin, only Endomorphy group had increcesed significantly.