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Sagrario Martinez-Ramirez,Moises Frias,Erika Y. Nakanishi,Holmer Savastano Jr. 한국콘크리트학회 2019 International Journal of Concrete Structures and M Vol.13 No.4
Non-fossil alternative fuels from biomass (agro-industrial, forestry and fodder plants) focus on getting cleaner, cheaper and more environmentally friendly energy sources directly related to the sustainable development of future societies. The resulting ash produced from the biomass calcination is a viable alternative for use as supplementary cementing materials in the construction industry. This study explores the scientific knowledge of calcium-silicate hydrate (C-S-H) gel formation during pozzolanic reaction between the biomass ash and calcium hydroxide through nuclear magnetic resonance technique with two different types of elephant grass ash that have different microstructure. The ash with the highest initial percentage of Q⁴ and Q³ units was found to react most actively and give rise to gels with the greatest inter-tetrahedral connectivity. In contrast, ash with higher content of total SiO₂, exhibited lower reactivity and the C-S-H gel formed is characterised by low inter-tetrahedral connectivity from the earliest ages. Evaluation of C-S-H gel by nuclear magnetic resonance (NMR), as main hydrated phase for the engineering properties, revealed the potential of this tool to determine the effectiveness of this type of grass as raw material in cementing matrices through the evolution of the microstructure of the gel C-S-H formed.
An Unusual Case of Extra-Enteric Blastocystosis in the Uterine Cervix
Yolanda Escutia-Guzman,Williams Arony Martinez-Flores,Joel Martinez-Ocana,Ramon Martinez-Pimentel,Marisol Benitez-Ramirez,Fernando Martinez-Hernandez,Sara Arroyo-Escalante,Mirza Romero-Valdovinos,Guad 대한기생충학열대의학회 2020 The Korean Journal of Parasitology Vol.58 No.5
Establishment of the Latin American Soil Information System Case Colombia - IRAKA
Araujo-Carrillo Gustavo Alfons,Martinez-Maldonado Fabio Ernes,Varon-Ramirez Viviana Marcela,Gomez-Latorre Douglas Andres,Estupinan-Casallas Jhon Mauric,Silva-Arero Elias Alexander,Gonzalez-Jaimes Edua 한국토양비료학회 2019 한국토양비료학회 학술발표회 초록집 Vol.2019 No.8
Leonardo Almeida,Daniel Martinez-Ramirez,Peter J. Rossi,Zhongxing Peng,Aysegul Gunduz,Michael S. Okun 대한신경과학회 2015 Journal of Clinical Neurology Vol.11 No.2
Tourette syndrome is a childhood-onset disorder characterized by a combination of motor andvocal tics, ofen associated with psychiatric comorbidities including attention defcit and hyperactivity disorder and obsessive-compulsive disorder. Despite an onset early in life, half of patients may present symptoms in adulthood, with variable degrees of severity. In select cases,the syndrome may lead to signifcant physical and social impairment, and a worrisome riskfor self injury. Evolving research has provided evidence supporting the idea that the pathophysiology of Tourette syndrome is directly related to a disrupted circuit involving the cortexand subcortical structures, including the basal ganglia, nucleus accumbens, and the amygdala. Tere has also been a notion that a dysfunctional group of neurons in the putamen contributes to an abnormal facilitation of competing motor responses in basal ganglia structures ultimately underpinning the generation of tics. Surgical therapies for Tourette syndrome have beenreserved for a small group of patients not responding to behavioral and pharmacological therapies, and these therapies have been directed at modulating the underlying pathophysiology. Lesion therapy as well as deep brain stimulation has been observed to suppress tics in at leastsome of these cases. In this article, we will review the clinical aspects of Tourette syndrome, aswell as the evolution of surgical approaches and we will discuss the evidence and clinical responses to deep brain stimulation in various brain targets. We will also discuss ongoing research and future directions as well as approaches for open, scheduled and closed loop feedback-driven electrical stimulation for the treatment of Tourette syndrome.
Israel Parra-Ortega,Diana Guadalupe Alcara-Ramirez,Alma Angelica Ronzon-Ronzon,Fermin Elias-Garcia,Jose Agustin Mata-Chapol,Alejandro Daniel Cervantes-Cot,Briceida Lopez-Martinez,Miguel Angel Villasis 한국영양학회 2021 Nutrition Research and Practice Vol.15 No.S
BACKGROUND/OBJECTIVES: Considering the high number of deaths from coronavirus disease 2019 (COVID-19) in Latin American countries, together with multiple factors that increase the prevalence of vitamin D deficiency, we aimed to determine 25-hydroxyvitamin D (25[OH]D) levels and its association with mortality in patients with critical COVID-19. SUBJECTS/METHODS: This was a prospective observational study including adult patients with critical COVID-19. Data, including clinical characteristics and 25(OH)D levels measured at the time of intensive care unit admission, were collected. All patients were followed until hospital discharge or in-hospital death. The patients were divided into those surviving and deceased patient groups, and univariate and multivariate logistic regression analyses were performed to determine independent predictors of in hospital mortality. RESULTS: The entire cohort comprised 94 patients with critical COVID-19 (males, 59.6%; median age, 61.5 years). The median 25(OH)D level was 12.7 ng/mL, and 15 (16%) and 79 (84%) patients had vitamin D insufficiency and vitamin D deficiency, respectively. The median serum 25(OH)D level was significantly lower in deceased patients compared with surviving (12.1 vs. 18.7 ng/mL, P < 0.001). Vitamin D deficiency was present in 100% of the deceased patients. Multivariate logistic regression analysis revealed that age, body mass index, other risk factors, and 25(OH)D level were independent predictors of mortality. CONCLUSIONS: Vitamin D deficiency was present in 84% of critical COVID-19 patients. Serum 25(OH)D was independently associated with mortality in critical patients with COVID-19.
Perez, Moises Roberto Vallejo,Contreras, Hugo Ricardo Navarro,Herrera, Jesus A. Sosa,Avila, Jose Pablo Lara,Tobias, Hugo Magdaleno Ramirez,Martinez, Fernando Diaz-Barriga,Ramirez, Rogelio Flores,Vazqu The Korean Society of Plant Pathology 2018 Plant Pathology Journal Vol.34 No.5
Clavibacter michiganensis subsp. michiganesis (Cmm) is a quarantine-worthy pest in $M{\acute{e}}xico$. The implementation and validation of new technologies is necessary to reduce the time for bacterial detection in laboratory conditions and Raman spectroscopy is an ambitious technology that has all of the features needed to characterize and identify bacteria. Under controlled conditions a contagion process was induced with Cmm, the disease epidemiology was monitored. Micro-Raman spectroscopy ($532nm\;{\lambda}$ laser) technique was evaluated its performance at assisting on Cmm detection through its characteristic Raman spectrum fingerprint. Our experiment was conducted with tomato plants in a completely randomized block experimental design (13 plants ${\times}$ 4 rows). The Cmm infection was confirmed by 16S rDNA and plants showed symptoms from 48 to 72 h after inoculation, the evolution of the incidence and severity on plant population varied over time and it kept an aggregated spatial pattern. The contagion process reached 79% just 24 days after the epidemic was induced. Micro-Raman spectroscopy proved its speed, efficiency and usefulness as a non-destructive method for the preliminary detection of Cmm. Carotenoid specific bands with wavelengths at 1146 and $1510cm^{-1}$ were the distinguishable markers. Chemometric analyses showed the best performance by the implementation of PCA-LDA supervised classification algorithms applied over Raman spectrum data with 100% of performance in metrics of classifiers (sensitivity, specificity, accuracy, negative and positive predictive value) that allowed us to differentiate Cmm from other endophytic bacteria (Bacillus and Pantoea). The unsupervised KMeans algorithm showed good performance (100, 96, 98, 91 y 100%, respectively).
Correlation between pr1 and pr2 Gene Content and Virulence in Metarhizium anisopliae Strains
( Ninfa M Rosas Garcia ),( Osvaldo Avalos De Leon ),( Jesus M Villegas Mendoza ),( Maribel Mireles Martinez ),( J E Barboza Corona ),( J C Castaneda Ramirez ) 한국미생물 · 생명공학회 2014 Journal of microbiology and biotechnology Vol.24 No.11
Metarhizium anisopliae is a widely studied model to understand the virulence factors that participate in pathogenicity. Proteases such as subtilisin-like enzymes (Pr1) and trypsin-like enzymes (Pr2) are considered important factors for insect cuticle degradation. In four M. anisopliae strains (798, 6342, 6345, and 6347), the presence of pr1 and pr2 genes, as well as the enzymatic activity of these genes, was correlated with their virulence against two different insect pests. The 11 pr1 genes (A, B, C, D, E, F, G, H, I, J, and K) and pr2 gene were found in all strains. The activity of individual Pr1 and Pr2 proteases exhibited variation in time (24, 48, 72, and 96 h) and in the presence or absence of chitin as the inductor. The highest Pr1 enzymatic activity was shown by strain 798 at 48 h with chitin. The highest Pr2 enzymatic activity was exhibited by the 6342 and 6347 strains, both grown with chitin at 24 and 48 h, respectively. Highest mortality on S. exigua was caused by strain 6342 at 48 h, and strains 6342, 6345, and 6347 caused the highest mortality 7 days later. Mortality on Prosapia reached 30% without variation. The presence of subtilisin and trypsin genes and the activity of these proteases in M. anisopliae strains cannot be associated with the virulence against the two insect pests. Probably, subtilisin and trypsin enzyme production is not a vital factor for pathogenicity, but its contribution is important to the pathogenicity process.