Falcine Sinus: Incidence and Imaging Characteristics of Three-Dimensional Contrast-Enhanced Thin-Section Magnetic Resonance Imaging

Ling Lin,Jin-Hua Lin,Jian Guan,Xiao-Ling Zhang,Jian-Ping Chu,Zhi-Yun Yang 대한영상의학회 2018 Korean Journal of Radiology Vol.19 No.3

Objective: To evaluate the incidence, characteristics, and variations of the falcine sinus with contrast-enhanced threedimentional (3D) thin-section magnetic resonance (MR) images. Materials and Methods: A retrospective review identified 1531 patients (745 males and 786 females, 2 months to 85 years) who underwent cranial MR imaging including T1-weighted imaging, T2-weighted imaging, T2-weighted fluid-attenuated inversion recovery, contrast-enhanced 3D thin-section sagittal scans, and MR venography, from June 2014 to January 2016. The incidence, characteristics of the falcine sinus, and coexisted intracranial lesions were confirmed by two neuroradiologists. Results: Falcine sinuses were identified in 81 (38 males and 43 females) cases (5.3%, 81/1531, 5 months to 76 years of age) with calibers ranging from 2.3 mm to 17.0 mm. Three major forms of falcine sinuses were defined: arch-like (n = 47), stick-like (n = 22), and bifurcated (n = 12). Persistent falcine sinuses were found in 57 cases, among which 3 cases showed complicated cerebral anomalies, and 2 cases showed smaller straight sinuses. Recanalization of falcine sinuses were found in 24 cases, including 17 cases with tumor compression, 6 cases with cerebral venous sinus thrombosis, and one case with hypertrophic meningitis. Conclusion: Falcine sinus is not as rare as has been reported previously. Most falcine sinuses are not associated with congenital cerebral abnormalities. Diseases that cause increased pressure in the venous sinus may lead to recanalization of falcine sinus. Illustrating the characteristics of falcine sinus may prompt a more comprehensive understanding and diagnosis of associated diseases, and avoid potential surgical damage in the future.

The Politics of Feminist Knowledge Production in Asian Countries

LING Lin 이화여자대학교 아시아여성학센터 2006 이화여자대학교 아시아여성학센터 학술대회자료집 Vol.2006 No.6

A Novel Cold-adapted Endoglucanase (M6A) from Microbacterium kitamiense S12 Isolated from Qinghai-Tibetan Plateau

Ling Lin,Na Qin,Linyan Guan 한국생물공학회 2019 Biotechnology and Bioprocess Engineering Vol.24 No.3

The gene M6A coding a novel cold-adapt endoglucanase was cloned from Microbacterium kitamiense Sa12 isolated from a wasteland in Saga, Qinghai-Tibetan Plateau. The deduced protein sequence encoded a 411residue polypeptide sharing similar identities with glycosyl hydrolase family 6 enzymes. The recombinant M6A displayed maximum hydrolysis activity of 1.51 U/mg toward soluble cellulose substrate, CMC at 35°C and pH 5.0, and the Km and Vmax value were 2.12 mg/mL and 15.33 μmol/min*mg, respectively. Interestingly, M6A exhibited significant activity even at ice cold condition, showing 30-40% relative activity at 0-5°C, and had good tolerance to Li+, K+, NH4+, Rb+, Ca2+, Mg2+, Zn2+, Mn2+, and Ni2+, expect divalent cation Cu2+ led to 30% residual activity. These properties might make M6A to be a promising candidate used in the psychrophilic industrial process and/ or the volatile and thermosensitive manufacturing process.

Antibacterial pathway of cefquinome against Staphylococcus aureus based on label-free quantitative proteomics analysis

Gao Linglin,Zhu Hao,Chen Yun,Yang Yuhui 한국미생물학회 2021 The journal of microbiology Vol.59 No.12

Cefquinome (CEQ) is a novel β-lactam antibiotic that exhibits excellent antibacterial activity against Staphylococcus aureus. However, the bacterial protein targets of CEQ are unclear. To evaluate the relationship between the pharmacokinetic/ pharmacodynamic (PK/PD) parameters of CEQ and strains with varying degrees of resistance and to elucidate bacterial protein responses to CEQ treatment, label-free quantitative proteomics analysis was conducted. The sensitive S. aureus ATCC6538 and the resistant 2MIC and 8MIC were tested for differentially expressed proteins. An in vitro model was treated with different concentrations of CEQ (3, 5, or 10 μg/ml) with different terminal half-lives (2.5 or 5 h) at different intervals (12 or 24 h). Differentially expressed proteins were evaluated using Gene Ontology analysis followed by KEGG pathway enrichment analysis and STRING network analysis. RT-qPCR was performed to validate the differentially expressed proteins at the molecular level. The results showed that the degree of resistance increased in a cumulative manner and increased gradually with the extension of administration time. The resistant strain would not have appeared in the model only if %T > mutant prevention concentration ≥ 50%. The expression of 45 proteins significantly changed following CEQ treatment, among which 42 proteins were obviously upregulated and 3 were downregulated. GO analysis revealed that the differentially expressed proteins were mainly present on cells and the cell membrane, participated in metabolic and intracellular processes, and had catalytic and binding activities. The RPSO, SDHB, CITZ, ADK, and SAOUHSC 00113 genes in S. aureus may play important roles in the development of resistance to CEQ. These results provided important reference candidate proteins as targets for overcoming S. aureus resistance to CEQ.

ERRATUM : Real-time Measurement of Full Field Retardation Near Quarter Wavelength

Liu, Longhai,Zeng, Aijun,Yuan, Qiao,Zhu, Linglin,Fang, Ruifang,Huang, Huijie Optical Society of Korea 2013 Current Optics and Photonics Vol.17 No.1

Real-time Measurement of Full Field Retardation Near Quarter Wavelength

Longhai Liu,Aijun Zeng,Qiao Yuan,Linglin Zhu,Ruifang Fang,HuijieHuang 한국광학회 2012 Current Optics and Photonics Vol.16 No.4

A real-time method to measure full field retardation near quarter wavelength is proposed. The circularly polarized beam passes through a sample with a large aperture. The measuring beam then goes through a quarter-wave plate and is then split by a Wollaston prism. An image with two sub-images is then detected by a high-speed image sensor. The full field retardation near quarter wavelength can be obtained in real time by processing the image. The measured retardation is independent of the fast axis angle of the sample and the fluctuation of the initial intensity. In experiments, a wedge waveplate is measured with different fast axis angle and initial intensity, and the full field retardations are acquired. The maximum and standard deviation of the full field retardation is 1.5° and 0.4°. The validity of the method is verified.

Natural Flow Characteristics of Liquid Rocket Engine Turbopump during Startup

Runze Zhou,Hui Chen,Liang Dong,Houlin Liu,Linglin Jiang,Zeyu Chen 한국유체기계학회 2022 International journal of fluid machinery and syste Vol.15 No.3

When the liquid rocket engine turbopump starts, the tank valve opens first before the pump is driven. Due to the tank and hydrostatic pressure, there is a passive flow phenomenon inside the pump called natural flow. The impeller is passively rotated by hydraulic impact, which impacts the stability of the turbopump during the initial startup period. In order to study the unsteady natural flow characteristics of the turbopump, the coupled CFD/6DOF solver is used for simulation and obtaining the variation of rotational speed, flow loss, and torque with time. The characteristics of the turbopump impeller's radial and axial force are analyzed. The internal flow field and pressure pulsation features were investigated. The results show that the rotational speed caused by natural flow increases exponentially with time. Furthermore, the natural flow loss and torque gradually decrease with the increased rotational speed and has distinct pulsation characteristics and periodicity. The backflow phenomenon in the flow channel becomes more complex. The suction chamber and the inducer have a buffering effect on the impact of the incoming flow, making the pressure distribution more uniform. Due to the matching angle and the rotor-stator interference, the pressure pulsation in the guide vanes has distinct sub-harmonic interference during the natural flow process.