Utility of Seated Lateral Radiographs in the Diagnosis and Classification of Lumbar Degenerative Spondylolisthesis

Issa Tariq Z.,Lee Yunsoo,Berthiaume Emily,Lambrechts Mark J.,Zaworski Caroline,Qadiri Qudratallah S.,Spracklen Henley,Padovano Richard,Weber Jackson,Mangan John J.,Canseco Jose A.,Woods Barrett I.,Kay 대한척추외과학회 2023 Asian Spine Journal Vol.17 No.4

Study Design: Retrospective cohort study.Purpose: Our goal was to determine which radiographic images are most essential for degenerative spondylolisthesis (DS) classification and instability detection.Overview of Literature: The heterogeneity in DS requires multiple imaging views to evaluate vertebral translation, disc space, slip angle, and instability. However, there are several restrictions on frequently used imaging perspectives such as flexion-extension and upright radiography.Methods: We assessed baseline neutral upright, standing flexion, seated lateral radiographs, and magnetic resonance imaging (MRI) for patients identified with spondylolisthesis from January 2021 to May 2022 by a single spine surgeon. DS was classified by Meyerding and Clinical and Radiographic Degenerative Spondylolisthesis classifications. A difference of >10° or >8% between views, respectively, was used to characterize angular and translational instability. Analysis of variance and paired chi-square tests were utilized to compare modalities.Results: A total of 136 patients were included. Seated lateral and standing flexion radiographs showed the greatest slip percentage (16.0% and 16.7%), while MRI revealed the lowest (12.2%, <i>p</i> <0.001). Standing flexion and lateral radiographs when seated produced more kyphosis (4.66° and 4.97°, respectively) than neutral upright and MRI (7.19° and 7.20°, <i>p</i> <0.001). Seated lateral performed similarly to standing flexion in detecting all measurement parameters and categorizing DS (all <i>p</i> >0.05). Translational instability was shown to be more prevalent when associated with seated lateral or standing flexion than when combined with neutral upright (31.5% vs. 20.2%, <i>p</i> =0.041; and 28.1% vs. 14.6%, <i>p</i> =0.014, respectively). There were no differences between seated lateral or standing flexion in the detection of instability (all <i>p</i> >0.20).Conclusions: Seated lateral radiographs are appropriate alternatives for standing flexion radiographs. Films taken when standing up straight do not offer any more information for DS detection. Rather than standing flexion-extension radiographs, instability can be detected using an MRI, which is often performed preoperatively, paired with a single seated lateral radiograph.

The Mathematical Operations in Bàtɔ̀nū Numeral System

Issa O. Sanusi,Lateefat Oluwatosin Yusuf 세종대학교 언어연구소 2018 Journal of Universal Language Vol.19 No.1

This paper examines the morphological properties of Bàtɔ̀nū numerals. The primary aim of the paper is to investigate the mathematical operations involved in the Bàtɔ̀nū numeral system. Based on this, the study has the following objectives: To show a descriptive analysis using the lexical phonology and morphology approach in the derivational processes of the numeral system, to show the relevant constraints or imperatives for well-formedness (addition, multiplication, subtraction and conjunction), to examine the representation of number in quality and amount, in line with the system of forming complex numbers and counting operations, finally, to determine the patterns and also the agreed method of counting in Bàtɔ̀nū. The study adopted Mohanan‟s (1982) and Kiparsky‟s (1982a) lexical phonological and morphological theories based on their problem-solving effectiveness and their reliability in handling African language data. Data for the study were generated from both primary and secondary sources. The informant method was adopted in collecting data, through the use of frame technique. The study concluded that Bàtɔ̀nū employed subtractive mechanism in the formation of numeral system. The language uses productively the additive element “kà”1 meaning „and‟ in adding other base numerals. Generally speaking, it could be observed that money counting system in Bàtɔ̀nū employs the mathematical operations of addition, subtraction and multiplication in order to achieve simplicity in the counting system.

Enhancement of nuclear radiation shielding and mechanical properties of YBiBO₃ glasses using La₂O₃

Issa, Shams A.M.,Ali, Atif Mossad,Tekin, H.O.,Saddeek, Y.B.,Al-Hajry, Ali,Algarni, Hamed,Susoy, G. Korean Nuclear Society 2020 Nuclear Engineering and Technology Vol.52 No.6

In this study, nuclear radiation shielding and rigidity parameters of Y (0.1-x)B0.6Bi1.8O3La2x glassy system were investigated in order to determine it's suitability for use as nuclear radiation shielding materials. Therefore, a group of bismuth borate glass samples with La₂O₃ additive were synthesized using the technique of melt quenching. According to the results, the increase of the La₂O₃ additive increases the density of the glass samples and the mass attenuation coefficient (μ_m) values, whereas the half-value layer (HVL) and mean free path (MFP) values decrease. The effective atomic number (Z_eff) is also enhanced with an increment of both mass removal cross section for neutron (Σ_R) and absorption neutron scattering cross section (σ_abs). In addition to the other parameters, rigidity parameter values were theoretically examined. The increase of La₂O₃ causes some other important magnitudes to increase. These are the average crosslink density, the number of bonds per unit volume, as well as the stretching force constant values of these glass samples. These results are in concordance with the increase of elastic moduli in terms of the Makishima-Mackenzie model. This model showed an increase in the rigidity of the glass samples as a function of La₂O₃.

Antiproliferative Effects of Free and Encapsulated Hypericum Perforatum L. Extract and Its Potential Interaction with Doxorubicin for Esophageal Squamous Cell Carcinoma

Issa Amjadi,Mohammad Mohajeri,Andrei Borisov,Motahare-Sadat Hosseini 대한약침학회 2019 Journal of pharmacopuncture Vol.22 No.2

Objectives: Esophageal squamous cell carcinoma (ESCC) is considered as a deadly medical condition that affects a growing number of people worldwide. Targeted therapy of ESCC has been suggested recently and required extensive research. With cyclin D1 as a therapeutic target, the present study aimed at evaluating the anticancer effects of doxorubicin (Dox) or Hypericum perforatum L. (HP) extract encapsulated in poly(lactic-co-glycolic acid) (PLGA) nanoparticles on the ESCC cell line KYSE30. Methods: Nanoparticles were prepared using double emulsion method. Cytotoxicity assay was carried out to measure the anti-proliferation activity of Dox-loaded (Dox NPs) and HP-loaded nanoparticles (HP NPs) against both cancer and normal cell lines. The mRNA gene expression of cyclin D1 was evaluated to validate the cytotoxicity studies at molecular level. Results: Free drugs and nanoparticles significantly inhibited KYSE30 cells by 55-73% and slightly affected normal cells up to 29%. The IC50 of Dox NPs and HP NPs was ~ 0.04-0.06 mg/mL and ~ 0.6-0.7 mg/mL, respectively. Significant decrease occurred in cyclin D1 expression by Dox NPs and HP NPs (P < 0.05). Exposure of KYSE-30 cells to combined treatments including both Dox and HP extract significantly increased the level of cyclin D1 expression as compared to those with individual treatments (P < 0.05). Conclusion: Dox NPs and HP NPs can successfully and specifically target ESCC cells through downregulation of cyclin D1. The simultaneous use of Dox and HP extract should be avoided for the treatment of ESCC.

Birth Weight Predicts Anthropometric and Body Composition Assessment Results in Adults: A Population-Based Cross-Sectional Study

Issa Al Salmi,Suad Hannawi 대한비만학회 2021 The Korean journal of obesity Vol.30 No.3

Background: A poor intrauterine environment is associated with increased risks of hypertension, chronic kidney disease, and/or diabetes. This study evaluated relationships between birth weight and body habitus in a representative sample of the general population. Methods: Adult participants were asked to complete a birth weight questionnaire. Associations between various current anthropometric and body composition measurements and birth weight were investigated. Results: Of 7,157 respondents, 4,502 reported their birth weight, which ranged from 0.4 to 7.0 kg with a mean and standard deviation of 3.37±0.7 kg; of these, 384 had low birth weights (LBWs; <2.5 kg). In females, lower birth weights were associated with lower height, weight, lean body mass (LBM), total body water (TBW), fat mass (FM), fat%, and fat-free mass (FFM) than those of higher older birth weights (quintiles); however, waist circumference (WC), and hip circumference (HC) were similar across quintiles. In males, LBW was similarly associated with lower height, weight, LBM, TBW, FM, fat%, and FFM, and also with lower WC and HC. The obesity markers such as WC, WHR, and body mass index (BMI) were 47%, 61%, and 45% greater, respectively, in LBW females compared to normal birth weight females, while these associations showed non-significant trend in males with LBW. Conclusion: In adult male and female respondents, LBW was associated with lower body habitus: central obesity and body fatness (BMI, FM, fat%, FFM, FM/FFM, and FM/FFM2) were more pronounced in females than males, even after taking into account current physical activity and socioeconomic status. These findings indicate LBW may contribute to high blood pressure, dysglycemia and metabolic-abnormalities in adults.

Dietary Intake and Accumulation of Phlorotannins in Abalone after Feeding the Phaeophyte Ecklonia stolonifera

Issa Bangoura(이싸 방구라),Yong-Ki Hong(홍용기) 한국생명과학회 2015 생명과학회지 Vol.25 No.7

전복을 4일간 굶긴 후 phlorotannin-고함유 곰피를 제공하여 이의 섭취 및 phlorotannin 축적정도를 조사하였다. 전복의 성장속도는 곰피 혹은 일반 사료로 쓰이는 다시마를 20일간 투여한 경우 서로 비슷하였다. 주된 phlorotannin 성분인 7-phloroeckol 및 eckol은 역상 HPLC로서 측정하였다. 7-phloroeckolol은 섭취 6일만에 전복 건조육 1g당 0.58±0.13 mg 정도 축적되었다. Eckol은 6일만에 전복 건조 육 1g당 0.25±0.05 mg 정도 축적되었으며 실험기간 내 그 정도를 유지하였다. 대조군로서의 다시마 투여 전복은 phlorotannin을 전혀 함유하지 않았다. Phlorotannin은 전복 조직내에서의 구성효소들에 의하여 분해되어 지는것으로 보인다. 그러므로 다양한 생리활성을 지닌 phlorotannin 물질들을 가진 고부가 가치의 전복 생산은 전복수확 6일전부터 간단히 사료만 phlorotannin-고함유 곰피로 바꾸어 공급함으로서 생산가능하다. Dietary intake and bioavailability of phorotannins in abalone was investigated after feeding with the phlorotannin-rich brown seaweed Ecklonia stolonifera after 4 days starvation. Reverse-phase high-performance liquid chromatography (RP-HPLC) affords isolation and quantification of the major phlorotannins of 7-phloroeckol and eckol, which were identified by mass spectrometry and nuclear magnetic resonance. Abalone growth and feed consumption rates were similar when fed either with the E. stolonifera or the common feed seaweed Saccharina japonica for 20 days. Throughout the feeding period, 7-phloroeckolol was accumulated in the abalone flesh tissue up to an average of 0.58±0.13 mg/g dry weight after 6 days. Eckol was reached to 0.25±0.05 mg/g dry tissue after 6 days, and maintained the level until end of feeding period. By feeding S. japonica as a control, no phlorotannins were detected in the abalone tissues. Both of the abalone, fed with E. stolonifera or S. japonica, had enzymes that decomposed 7-phloroeckol and eckol in muscle tissues, with similar degradation rates of ?0.05 or less and ?0.05 mg/ml/hr, respectively. Phlorotannins were reduced by constitutive enzymes in abalone tissues. Therefore, value-added abalone containing bioactive phlorotannins can be produced by simply changing the feed to the phlorotannin-rich brown seaweed E. stolonifera 6 days before harvest.

Display power analysis and design guidelines to reduce power consumption

Issa, Joseph The Korean Infomation Display Society 2012 Journal of information display Vol.13 No.4

Cold cathode fluorescent lamps (CCFLs) are used to provide lighting for liquid crystal displays (LCDs). This paper presents a set of guidelines for measurement characterization and design to reduce the power consumption of CCFL LCD backlight inverters and panel electronics. The proposed methods aim to reduce the backlight power consumption by fine-tuning a back-light inverter for a specific LCD, using several methods. First, the authors describe their power measurement methodology; and next, they identify different areas for tuning a backlight inverter for a given display. The experiment results showed that power savings can range from 50 to 200mW if the backlight inverter is properly tuned. This paper also proposes an optimized configuration for light-emitting device (LED) panels to reduce power loss by selecting a LED with a specific input voltage and number of cells to help minimize power loss.

Strategic Information Systems Alignment: Alignment of IS/IT with Business Strategy

Issa-Salwe, Abdisalam,Ahmed, Munir,Aloufi, Khalid,Kabir, Muhammad Korea Information Processing Society 2010 Journal of information processing systems Vol.6 No.1

Using information systems effectively requires an understanding of the organisation, management, and the technology shaping the systems. All information systems can be described as organisational and management solutions to challenges posed by the environment. The advances in information systems have affect on our day-to day lives. As the technology is evolving immensely so are the opportunities in a healthy way to prepare the organisation in the competitive advantage environment In order to manage the IS/IT based systems, it is important to have an appropriate strategy that defines the systems and provide means to manage them. Strategic Information Systems Alignment (SISA) is an effective way of developing and maintaining the IS/IT systems that support the business operations. Alignment of the IS/IT plans and the business plans is essential for improved business performance, this research looks at the key features of SISA in the changing business circumstances in Saudi Arabia.

On the characteristics and seismic study of Hat Knee Bracing system, in steel structures

Issa JafarRamaji,Massood Mofid 국제구조공학회 2012 Steel and Composite Structures, An International J Vol.13 No.1

In this study, a new structural bracing system named ‘Hat Knee Bracing’ (HKB) is presented. In this structural system, a special form of diagonal braces, which is connected to the knee elements instead of beam-column joints, is investigated. The diagonal elements provide lateral stiffness during moderate earthquakes. However the knee elements, which is a fuse-like component, is designed to have one plastic joint in the knee elements for dissipation of the energy caused by strong earthquake. First, a suitable shape for brace and knee elements is proposed through elastic studying of the system and several practical parameters are established. Afterward, by developing applicable and highly accurate models in Drain-2DX, the inelastic behavior of the system is carefully considered. In addition, with inelastic study of the new bracing system and comparison with the prevalent Knee Bracing Frame system (KBF model) in nonlinear static and dynamic analysis, the seismic behavior of the new bracing system is reasonably evaluated.

COHOMOLOGY AND DEFORMATIONS OF HOM-LIE-YAMAGUTI COLOR ALGEBRAS

Issa, A. Nourou The Kangwon-Kyungki Mathematical Society 2021 한국수학논문집 Vol.29 No.2

Hom-Lie-Yamaguti color algebras are defined and their representation and cohomology theory is considered. The (2, 3)-cocycles of a given Hom-Lie-Yamaguti color algebra T are shown to be very useful in a study of its deformations. In particular, it is shown that any (2, 3)-cocycle of T gives rise to a Hom-Lie-Yamaguti color structure on T⊕V , where V is a T-module, and that a one-parameter infinitesimal deformation of T is equivalent to that a (2, 3)-cocycle of T (with coefficients in the adjoint representation) defines a Hom-Lie-Yamaguti color algebra of deformation type.