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Abanmi, Abdullah,Harthi, Fahad Al,Agla, Rokaiyah Al,Khan, Haseeb Ahmad,Tariq, Mohammad Korean Society for Biochemistry and Molecular Biol 2005 Journal of biochemistry and molecular biology Vol.38 No.3
Alanine at residue 73 (Ala-73) and aspartate at residue 9 (Asp-9) are characteristic to both Cw6 and Cw7 alleles of HLA-C gene and have been suggested as possible markers for psoriasis vulgaris (PsV). However, the results from various ethnic groups/populations are contradictory and inconclusive. In this study, an attempt has been made to examine the association between HLA-C (Ala-73 and Asp-9) and susceptibility to PsV among Saudi patients. Genomic DNA was extracted from 25 Saudi PsV patients and 75 control subjects. Polymerase chain reaction (PCR) was performed to amplify HLA-C sequences using earlier reported primers, C133P and C243PR. Sequence-specific primers were used to specifically detect nucleotide coding for Ala-73 and Asp-9 in all the subjects. The results showed significantly higher frequency of Asp-9 (84.0% versus 61.3%) in PsV patients as compared to controls (p < 0.05, 2-tailed Fisher's exact test). The frequencies of Ala-73 among PsV patients (92%) and controls (88%) did not differ significantly.
Nasir, Muhammad,Johari, Megat Azmi Megat,Yusuf, Moruf Olalekan,Maslehuddin, Mohammed,Al-Harthi, Mamdouh A. Techno-Press 2020 Advances in concrete construction Vol.10 No.5
This study investigated the effect of alkaline activators - NaOH<sub>aq</sub> (NH) (NH: 0-16 M) and Na<sub>2</sub>SiO<sub>3aq</sub> (NS) (NS/NH: 0-3.5) in the synthesis of silico-manganese fume (SMF) and ground blast furnace slag (BFS) blended alkali-activated mortar (AASB). The use of individual activator was ineffective in producing AASB of sufficient fresh and hardened properties, compared to the synergy of both activators. This may be attributed to incomplete dissolution and condensation of oligomers required for gelation of the binder. An inverse relationship was noted among the fresh properties and the NH concentration or NS/NH ratio. This was influenced by the dissolution and condensation of silicate monomers under polymerization process. The maximum 28-day strength of ~45 MPa, setting time of 60 min and flow of 182 mm was obtained with the use of combined activators (10M-NH and NS/NH=2.5). The combined activators at NS/10M-NH=2.5 constituted SiO<sub>2</sub>/Na<sub>2</sub>O, H<sub>2</sub>O/Na<sub>2</sub>O and H<sub>2</sub>O/SiO<sub>2</sub> molar ratio of 1.61, 17.33 and 10.77, respectively. This facilitated the formation of C-S-H, C/K-A-S-H and C-Mn-S-H in the framework together with an increase in the crystallinity due to more silicate re-organization within the aluminosilicate chain. On comparison of the high concentrated with mild alkali synthesized product, it revealed that the concentration of OH<sup>-</sup> and Si monomers together with alkali metals influenced the dissolution of precursors and embedment of the constituent elements in the polymeric matrix. These factors eventually contributed to the microstructural densification of the mortar prepared with NS/10M-NH=2.5 thereby enhancing the compressive strength.
Abdularahman B.O. Mohamed,Salwa Ibrahim Hindawi,Sameer Al-harthi,Qamre Alam,Mohammad Zubair Alam,Absarul Haque,Waseem Ahmad,Ghazi A Damanhouri 대한혈액학회 2016 Blood Research Vol.51 No.4
BackgroundCharacterization of the ABO blood group at the phenotype and genotype levels is clinically essential for transfusion, forensics, and population studies. This study elucidated ABO phenotypes and genotypes, and performed an evaluation of their distribution in in-dividuals from the western region of Saudi Arabia.MethodsOne-hundred and seven samples underwent standard serological techniques for ABO blood group phenotype analysis. ABO alleles and genotypes were identified using multi-plex polymerase chain reaction, and electrophoretic analysis was performed to evaluate the highly polymorphic ABO locus.ResultsA phenotype distribution of 37.4%, 30.8%, 24.3%, and 7.5% was found for blood groups O, A, B, and AB respectively in our study cohort. Genotype analysis identified 10 genotype combinations with the O01/O02 and A102/O02 genotypes being the most frequent with frequencies of 33.6% and 14.95%, respectively. Common genotypes such as A101/A101, A101/A102, A101/B101, B101/B101, and O01/O01 were not detected. Similarly, the rare genotypes, cis-AB01/O02, cis-AB01/O01, and cis-AB01/A102 were not found in our cohort. The most frequently observed allele was O02 (35.98%) followed by the A102 allele (17.76%). Furthermore, our findings are discussed in reference to ABO allele and geno-type frequencies found in other ethnic groups.ConclusionThe study has a significant implication on the management of blood bank and transfusion services in Saudi Arabian patients.
Momentum Strategies and Stock Returns: A Case of Saudi Stock Market
Muhammad Asif KHAN,Ramiz Ur REHMAN,Muhammad Ishfaq AHMAD,Majed Al HARTHI 한국유통과학회 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.7
This paper investigates the presence of momentum profits in the Saudi stock market. The study applied a quantitative method by utilizing monthly closing prices of 194 listed firms on Tadawal (Saudi Stock Market). The data from January 2010 to February 2019 is taken from the Tadawal market database for analysis. The sample is further divided into two equal sub-samples based on the structural changes that occurred in the Saudi stock market. Moreover, the high- and low-value traded portfolios are also constructed to examine the presence of momentum profits. Sixteen investment strategies are formed for each sample. The results show a very strong presence of momentum profits in the Saudi stock market for the full sample as well as for the sub-samples. The momentum profits are observed for a longer investment horizon. The results confirm that the short or medium-term formation of portfolios produces negative momentum returns for high-value traded stocks. The low-value traded stocks portfolios give similar results to the full sample results in terms of momentum profits. The results suggest that an investor should keep an eye on the past performance of desired stocks for at least three-nine months in which they are willing to invest.
S.H. Abdul Kaleel,Bijal Kottukkal Bahuleyan,S.K. De,Masihullah Jabarulla Khan,Rachid Sougrat,Mamdouh A. Al-Harthi 한국공업화학회 2012 Journal of Industrial and Engineering Chemistry Vol.18 No.5
Ethylene polymerization was carried out using highly active metallocene catalysts (Cp2ZrCl2 and Cp2TiCl2) in combination with methylalumoxane. Titanium(IV) oxide containing 1% Mn as dopant was used as nanofillers. The influence of filler concentration, reaction temperature and pressure on the catalytic activity and polymer properties was investigated. There was a fourfold increase in the activity of zirconocene catalyst by addition of doped-titania. The morphology indicates that the doped-titania nanoparticles have a nucleus effect on the polymerization and caused a homogeneous PE shell around them. The optimum condition for polymerization was found to be 30 8C.
Taye Saheed Kazeem,Mukarram Zubair,Muhammad Daud,Nuhu Dalhat Mu’azu,Mamdouh Ahmed Al-Harthi 한국화학공학회 2019 Korean Journal of Chemical Engineering Vol.36 No.7
Ternary layered double hydroxide, MgCoAl (MCA) and its graphene-based composite (G/MCA) were fabricated via a simple co-precipitation technique. The composites along with their calcined products (MCA-C) and (G/ MCA-C) were used as adsorbents for the removal of an anionic dye, methyl orange (MO), from aqueous phase. The characterization results (scanning electron microscopy and transmission electron microscopy) revealed homogeneous dispersion of graphene onto the MCA. Calcination of G/MCA resulted in a rough and heterogeneous surface with significant improvement in oxygen functionalities and surface area, which plays a crucial role in improved dye adsorption performance. Adsorptive equilibrium was established at 240 min for MCA and G/MCA and 180min for MCA-C and G/MCA-C respectively at pH 3 and optimum dosage of 10mg. The Redlich-Peterson and Langmuir isotherm models closely describe the adsorption process with maximum adsorption capacities of 357.14, 384.62, 400.12 and 434.78mg/g for MCA, G/MCA, MCA-C, and G/MCA-C respectively. Kinetics modeling indicates the adequacy and fitness of the pseudo-second-order model. A thermodynamics evaluation substantiates the exothermic nature of the adsorption processes. The MO-graphene ternary LDH composite adsorption process is controlled by several mechanisms including hydrogen bonding, surface adsorption, chemical and electrostatic interactions with surface reconstruction. The high removal efficiency of the MO coupled with high recovery and reusability of these nanomaterials showcases their potential for deployment in wastewater treatment.
Evaluation of novel Mg/Al/Ni-BaFe ternary layered hydroxides uptake of methyl orange dye from water
Nuhu Dalhat Mu’azu,Nabeel Jarrah,Mukarram Zubair,Mohammad Saood Manzar,Taye Saheed Kazeem,Mamdouh Al-Harthi 한국화학공학회 2019 Korean Journal of Chemical Engineering Vol.36 No.12
MgAlNi-BaFe ternary layered hydroxide (UMLDH) and its calcined (CMLDH) form were synthesized and tested as adsorbents for methyl orange dye (MO) uptake from water. The adsorptive performances of the new magnetic nanocomposites were modeled, evaluated and optimized via response surface methodology (RSM). The UMLDH and CMLDH maximum removal efficiency and adsorption capacities data were fitted into RSM models with insignificant lack of fit (p-values<0.05) and high R2=0.991-0.997. The UMLDH and CMLDH MO adsorption capacities increased with decrease in both pH and initial MO concentration and decreased when the temperature was increased. Under optimal operating conditions, pseudo-second-order described kinetics of MO sorption on the nanocomposites, while the Freundlich isotherm gave the best fits for both the two adsorbents. The MO uptake simultaneously incorporated both mono and multi-layer surface adsorption involving strong electrostatic attraction and chemical interactions between MO and the adsorbents surface functional groups. Respectively, the obtained maximum Langmuir theoretical sorption capacity of 715.44 and 708mg/g, indicated profoundly improved MO sorption capacities compared with many other magnetic-LDHs. These results demonstrate the potential of MgAlNi-BaFe as excellent adsorbents for effective remediation of dyes wastewater effluents.