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류공식 군산대학교 1979 論文集 Vol.1 No.1
This paper is an attempt to survey and analyze copper contents in the sea-water of downstream of the GumRiver which empties into the Yellow sea holding contaminated water from the mining and metallic industries. To survey and analyze it, eight different areas of sea-water of the Gum River was picked up from the upper surfaces and the lower stratum at each full and ebb tides on April 20, 1978. Then careful examination in to the copper contents was made and the following results were obtained : 1. The sea-water of examining area of the downst rcam of the Gum River holds 0.048-0.141 parts per million (PPM) of copper contents, and the average is around 0.079 (PPM) 2. Copper contents at each full and ebb tides made some differences respectively. At ebb) tide copper contents (0.095) is rather heavier than that (0.063) at the full tide. It indicated that the sea-water comprised much copper contents. 3. It has been examined that the lower stratum (0.092) contains more copper contents than in the upper surface of the sea-water (0.067). 4. The result obtained after the examination by each area indicated that around Jang Hang Refinery, 1st area, the copper contents is heaviest (0.125) and the mouth of downstream of the Gum River, 3rd area, revealed the least amount (0.046) of copper contents. 5. Since the turbidity at the downstream of the Gum River is thick when seen through the naked eyes, the contamination seems to be serious, but it is thought that the pollution of the Gum River is not still sorious in terms of the quantity of copper, on of heavy metal, contained.
Near-Optimal Tracking Control for Discrete-time Systems with Delayed Input
Gong-You Tang,Shi-Yuan Han,Cheng-Ming Zhang 제어·로봇·시스템학회 2010 International Journal of Control, Automation, and Vol.8 No.6
This paper considers the near-optimal tracking control problem for discrete-time systems with delayed input. Using a variable transformation, the system with delayed input is transformed into a non-delayed system, and the quadratic performance index of the optimal tracking control is transformed into a relevant format. The optimal tracking control law is constructed by the solution of a Riccati matrix equation and a Stein matrix equation. A reduced-order observer is constructed to solve the physically realizable problem of the feedforward compensator and a near-optimal tracking control is obtained. Simulation results demonstrate the effectiveness of the optimal tracking control law.
You Zhou,Weihong Zhou,Fangxi Xie,Yu Liu,Xiaoping Li,Xun Gong 한국자동차공학회 2023 International journal of automotive technology Vol.24 No.1
A new mechanical-hydraulic variable valve actuation (VVA) system was developed and a thin-wall orifice velocity control system were analyzed. Meanwhile, influence of speed, needle valve overflow area, oil temperature and oil supply pressure on valve motion characteristics were explored, as well as the VVA system have been applied on a single-cylinder engine preliminary. By the VVA system, valve lifts can be adjusted from maximum of 8.7 mm to fully closing. Valve seating velocity decreased with orifice diameter reducing. Seating velocity can be maintained below 0.5 m/s with 0.8 mm diameter of thin-wall orifice and 3 mm check valve moving distance. Besides that, velocity control system also can help improve the coefficient of cyclic variation of maximum valve lift. Except for the needle valve closing state, valve lift decreased with oil temperature increasing and operating speed reducing under the same needle valve state. Oil supply pressure hardly had no influence on valve lifts, but delayed valve opening timing with pressure decreasing. Thin-wall orifice seating velocity control system was not sensitive to variable oil temperature and supply pressure. Compared with conventional engine, adjusting intake valve by VVA system under un-throttle internal EGR strategy, can improve BSFC and NOX emissions significantly about 13.8 % and 19.8 % on 6 bar IMEP.
MicroRNA-766-3p Inhibits Tumour Progression by Targeting Wnt3a in Hepatocellular Carcinoma
You, Yu,Que, Keting,Zhou, Yun,Zhang, Zhen,Zhao, Xiaoping,Gong, Jianpin,Liu, Zuojin Korean Society for Molecular and Cellular Biology 2018 Molecules and cells Vol.41 No.9
Recent studies have indicated that microRNAs (miRNAs) play an important role in hepatocellular carcinoma (HCC) progression. In this study, we showed that miR-766-3p was decreased in approximately 72% of HCC tissues and cell lines, and its low expression level was significantly correlated with tumour size, TNM stage, metastasis, and poor prognosis in HCC. Ectopic miR-766-3p expression inhibited HCC cell proliferation, colony formation, migration and invasion. In addition, we showed that miR-766-3p repressed Wnt3a expression. A luciferase reporter assay revealed that Wnt3a was a direct target of miR-766-3p, and an inverse correlation between miR-766-3p and Wnt3a expression was observed. Moreover, Wnt3a up-regulation reversed the effects of miR766-3p on HCC progression. In addition, our study showed that miR-766-3p up-regulation decreased the nuclear ${\beta}-catenin$ level and expression of Wnt targets (TCF1 and Survivin) and reduced the level of MAP protein regulator of cytokinesis 1 (PRC1). However, these effects of miR-766-3p were reversed by Wnt3a up-regulation. In addition, PRC1 upregulation increased the nuclear ${\beta}-catenin$ level and protein expression of TCF1 and Survivin. iCRT3, which disrupts the ${\beta}-catenin-TCF4$ interaction, repressed the TCF1, Survivin and PRC1 protein levels. Taken together, our results suggest that miR-766-3p down-regulation promotes HCC cell progression, probably by targeting the Wnt3a/PRC1 pathway, and miR-766-3p may serve as a potential therapeutic target in HCC.
공성화,방찌야,서민숙,현신숙,김희정,이미애1,이미애2,유현희,허재경,김은애,박경숙 성인간호학회 2004 성인간호학회지 Vol.16 No.1
Purpose: The purpose of this study is to evaluate the knowledge and attitudes of oncology ward nurses toward cancer pain management and to find ways to improve the educational program for nurses. Method: A total of 209 nurses working at the oncology ward of three hospitals in Seoul and a Gyenggi Province. The survey instrument used was the 32-item scale for evaluating nurses knowledge and attitudes originally developed by McCaffery and Ferrell'(1990). that was by Kim'(1997). Result: In terms of the nurses knowledge of pain management. the result showed that the nurses scored an average of 67.8 out of 100 for phamacokinetics of opioids. 84.8 for classification of analgesics, 60.1 for pain assessment, and 70.7 for drug administration. 18.2% of the nurses hesitate to inject the narcotic agent because of concerns regarding the drug's potential side effects. there was significant difference in the knowledge of pain management according to the general characteristics of pain in terms of the nurses age(p=.001), position (p=.016). years of experiences(p=.002), experience of cancer pain education(p= .001). Conclusion: The also showed that nurses working at cancer ward lack knowledge. It is important to provide intensive education to nurses about cancer pain management.
Gong Huihui,You Jun,Zhang Xiurong,Liu Yanzhong,Zhao Fengtao,Cui Xinxiao,Zhang Yujuan 한국식물학회 2021 Journal of Plant Biology Vol.64 No.6
Long non-coding RNAs (lncRNAs) play important roles in various biological regulatory processes in which complicated mechanisms are involved, as well as stress-responsive regulation. However, the number, characteristics, sequences and possible effects of lncRNAs in sesame response to salt stress are poorly understood. In this study, a total of 2482 lncRNAs were identified from two contrasting sesame genotypes under salt stress using high-throughput RNA sequencing, of which 599 were intergenic lncRNAs, 293 were antisense lncRNAs and 786 lncRNAs may encode proteins. Expression pattern analysis showed that most lncRNAs were expressed at a low level and a total of 700 differentially expressed lncRNAs were characterized as salt responsive in sesame. A large number of potential target genes of lncRNAs were predicted, and functional annotation analysis indicated that the differentially expressed lncRNAs in salt stress may regulate protein-coding genes involved in several important pathways related to glycolysis/gluconeogenesis, flavonoid biosynthesis, monoterpenoid biosynthesis, biotin metabolism, galactose metabolism, cyanoamino acid metabolism and carotenoid biosynthesis. Integrated analysis of lncRNAs and mRNAs revealed the regulatory role of lncRNAs associated with salt resistance in sesame, and provided convincing proof of the interplay of specific candidate target genes with lncRNAs. Our results indicated that a comprehensive set of lncRNAs with potential target genes were responsive to salt stress in sesame seedlings. These findings provided important information on salinity responses and adaptation of sesame to salt stress and may constitute useful resources for more comprehensive studies on gene regulation in sesame.