肺炎 誘發菌의 生育을 抑制하는 韓藥材 探索에 關한 硏究

정병운,서운교,정지천,한영환 동국대학교 한의학연구소 1999 東國韓醫學硏究所論文集 Vol.7 No.2

韓藥材 중 肺炎의 치료효과가 기대되는 淸熱化痰, 止咳平喘藥을 중심으로 23種의 藥材를 사용하여 肺炎을 유발하는 K. pneumoniae, S. pyogenes 및 S. pneumoniae 세균의 생육을 억제하는 藥材를 탐색하고, 탐색된 藥材의 추출물에 대한 세균의 最小生育抑制濃度를 측정하였다. 韓藥材의 水溶性 추출물 중 黃連, 胡黃蓮, 敗醬, 黃芩이 K. pneumoniae에서, 黃連이 S. pyogenes에 대해서 생육억제 효과가 있었으며, S. pneumoniae에 대한 比較沮止環의 直徑은 黃連, 鳥梅, 五味子, 黃芩이 우수하였으나 黃連 추출물 사용시 병원균 모두에서 生育沮止環의 크기가 가장 크게 나타났으며 對照群로 사용된 大腸菌과 枯草菌에서도 어느 정도의 抗細菌 효과를 볼 수 있었다. 에탄올 추출물에서는 敗醬, 黃芩, 五味子, 鳥梅가 K. pneumoniae 세균의 생육을 억제하였으며, S. pyogenes 세균은 黃連, 五味子, 鳥梅, 馬兜鈴찾, 黃芩에 의하여 생육이 억제되어 黃連은 水溶性 및 에탄올 溶解性 주출물에서 모두 우수한 抗細菌 효과를 보여주고 있다. 각 세균에 대한 最小生育沮止濃度(MIC)는 K. pneumoniae 세균일 경우 黃連 및 黃芩의 水溶性 추출물과 鳥梅 및 敗醬의 에탄올 溶解性 추출물이 유의성을 보였으며, S. pyogenes 세균은 黃連의 水溶性 및 에탄올 溶解性 추출물과 鳥梅의 에탄올 溶解性 추출물, S. pneumoniae 세균은 黃連과 鳥梅의 水溶性 및 에탄올 溶解性 주출물에서 유의성이 나타났다. 이상의 결과를 통하여 黃連, 五味子, 鳥梅, 黃芩, 胡黃蓮, 敗醬의 水溶性 및 에탄올 溶解性 추출물이 肺炎 誘發菌f K. pneumoniae, S. pyogenes, S. pneumoniae에 對하여 우수한 生育抑制 作用을 나타냄을 알 수 있었다. The various oriental herbal medicines, which have usually been used for treatment of reducing fever, purging intense heat and detoxication, were screened to determine the antibacterial activity and the minimal inhibitory concentration against pulmonary disease-causing Klebsiella pneumoniae, Streptococcus pyogenes, and Streptococcus pneumoniae. The results obtained were as follows: 1. Among the 23 oriental medicines tested, the water-soluble extracts of Coptis japonica, Scutellaria baicalensis and Picrorrhiza kurroca showed the antibacterial activity against K. pneumoniae and that of C. japonica against S. pyogenes. The antibacterial activities of C. japonica, Prunus mume, Schizandra chinesis, Scutellaria baicalensis were also found against S. pyogenes. When C. japonica was used, the high antibacterial activity was shown against Bacillus subtilis and other extracts showed a little activity against B. subtilis and E. coli as a control. 2. The ethanol-soluble extracts of Patrinia scabriosaefolia, P. mume, S. baicalensis, S. chinensis showed the antibacterial activity against K. pneumoniae and those of S. baicalensis, C. japonica, S. chinensis P. mume against S. pyogenes and S. pneumoniae. However, those extract showed a little antibacterial activity against B. subttilis and E. coli except for that the extract of C. japonica showed comparatively high growth inhibition of B. subtilis. 3. Among the medicinal herbs tested, the water- and ethanol extracts of C. japonica showed very extcellent antibacterial activity against the pathogenic bacteria and controls. 4. When the water-soluble extracts of C. japonica and S. baicalensis, minimal inhibitory concentrations (MICs) against K. pneumoniae were 10 ㎎/㎖ and 22 ㎎/㎖, respectively. The MICs of the ethanol-soluble extracts of P. mume and P. scabriosaefolia were 5 ㎎/㎖ and 20 ㎎/㎖, respectively. 5. For the MICs against S. pyogenes, C. japonica showed 15 ㎎/㎖ with the water-soluble extract and P. mume and C. japonica with the ethanol-souble extract did 5 ㎎/㎖ and 10 ㎎/㎖, respecitively. 6. For the MICs against S. pneumoniae, C. japonica and P. mume with the water- and ethanol-souble extract showed 5 ㎎/㎖ and 10 ㎎/㎖, respecitively. As a result, the highest antibacterial activity was found in the water- and ethanol-soluble extracts of C. Japonica against pulmonary disease-causing bacteria, K. pneumoniae, S. pyogenes, and S. pneumoniae. Also, the water- and ethanol-soluble extracts of S, chinensis, P. mume, S. baicalensis and P. kurrooa showed high antibacterial activities.

E.B 용접된 18% Ni 마르에이징강 박판의 잔류응력및 변형에 관한 연구

정병호,박흥일 釜山工業大學校 1994 論文集 Vol.36 No.-

The residual stress and distortion in 300 grade 18% Ni maraging steel sheet welded with electron beam have been investigated. The main results obtained from this study are as follows; (1) The residual stress showed small compressive in weld centerline and tensile stress in heat affected zone. The residual stress in weldment was almost completely removed by solution treatment at 820℃, 1hour after welding. (2) Transverse bending distortion in bead on plate welding and longitudinal bending distortion in butt welding were mainly observed.

책임운영기관 제도운영의 평가

김병섭,정진우,임보영 서울대학교 행정대학원 2001 行政論叢 Vol.39 No.1

지난 1년간 10개의 책임운영기관들의 운영실태를 분석한 결과 '기관장채용', '조직관리', '인사관리', '재무관리' 부문에 관해 법령상으로는 '자율성' 보장이 일부 제도화되어 있었으나 책임성에 대한 관심 때문에 자율성이 상당히 제약되고 있는 것으로 나타났다. 특히 '재무관리'상의 제약이 가장 많은 것으로 나타났다. 책임운영기관제도가 제대로 정착되기 위해서 자율성이 보다 강화되어야 할 것이며 이와 관련한 정책적 제언을 제시하였다.

소프트웨어 변경관리 노력 추정 모델

손혜정,이병걸 서울여자대학교 컴퓨터과학연구소 2007 정보기술논문지 Vol.5 No.-

소프트웨어 개발주기에서 변경작업은 빈번하게 일어나며, 반드시 관리의 대상이 되어야 한다. 뿐만 아니라 변경작업에 대한 정량적인 측정을 통해 불필요하게 일어나는 변경작업의 원인을 찾아 제거해야 한다. 기존에 가장 널리 알려진 변경관리의 공수(Change Effort)를 추정할 수 있도록 제안된 모델은 개발자의 주관적인 요소가 포함되어 있어 모델의 성능을 검증해볼 수 없는 단점이 있으며, 그 외의 제안되어 있는 모델의 수가 적어 그 성능의 비교가 쉽지 않다. 따라서 본 논문에서는 NASA MDP Dataset 내의 defect data를 이용한 통계분석을 통해 모델을 객관적 요소로 구성하였고, 기존 모델에서 배재된 변경작업의 우선순위라는 새로운 변수를 추가했다. 본 논문에서 제안된 모델은 기존 모델에 비해 일반적인 적용이 쉽고, 개발 조직에서 변경 관리 노력을 추정함으로써 이를 통해 형상관리의 도입 시점을 예측할 수 있다. Changes occurs frequently in software life cycle, so should be managed. Moreover, unnecessary changing factors should be terminated by quantitative measurements. Current studies suggested to infer change efforts includes the subjective factors of development. Thus it is hard to be verified and be compared to a small number of suggested models. This paper proposes a new model consisting of objective factors through statistical analysis using defect data in NASA MDP Dataset. And we add a new factor priority of change to a model. The proposed model in this paper is more easier to apply and makes development organizations can estimate adoption time for Software Configuration Management(SCM) throughout inferring change effort.

비등열전달계수에 대한 상관관계식 개발

金秉宙,金廷憲 弘益大學校 科學技術硏究所 1997 科學技術硏究論文集 Vol.8 No.-

In the present study, experimental data on the boiling heat transfer coefficients have been collectd to construct data-base for the easy comparison and analysis of expermental conditions, characteristics of refrigerants used in the experiment, and the boiling heat transfer coefficient. Correlations published in the open literature for the boiling heat transfer coefficient of pure refrigerant in smooth tube were analyzed based on the data-base. New correlation has been developed and its reliability was confirmed. The results of the present study could be used in the development of correlation for the application to the practical phase change heat transfer process in a wide range.

높이 均衡 트리에 의한 算術式의 竝列性 探索 알고리즘

黃河玎,姜秉旭 嶺南大學校 工業技術硏究所 1988 연구보고 Vol.16 No.2

An efficient algorithm for detecting paprallel processable tasks in arithmetic expressions are proposed in the paper. The priority, commutative law and associative law of arithmetic operations are used to convert the syntax trees to the height-balanced trees for optimal task allocation. A preprocessor, which analyses the expressions in a subset form of the C-language, was designed and implemented. The results from various tests showed correctness and effectiveness of the algorithm.

Anemone의 花粉 2型現象과 葯培養에 關한 硏究

李炳基,高正愛,殷鍾旋 全北大學校 1987 論文集 Vol.29 No.-

In order to investigate the effects fo anther stage, optimal basic media, kinds and concentrations of plant growth regulators, sucrose concentrations for callus and embryo formation, pollen dimorphism and low temperature pretreatment of floral bud on the emergence of embryogenic S pollen of Anemone coronaria in vivo or in vitro, anthers of Anemone coronaria were cultured in Murashige & Skoog's(M&S) and Bourgin & Nitsch's(H) basic media with the combination of auxins and cytodinins. The measurement of anther length could be reliable criterion in determining the optimal anther stages, while floral bud length and anther color could not be a reliable criterion because same sized floral buds showed various degree of microspore development. M&S basic media was more effective on callus formation than H basic media. The addition of plant growth regulators of NAA and BA with M&S basic media was effective on callus formation than 2,4-D and kinetin. The best results was obtained from the combination of 0.5mg/l NAA and 2.0 mg/l BA. The best response of calus formation was obtained from 3% sucrose concentration on M&S basic medium supplemented with 0.5mg/l NAA and 2.0mg/l BA. B type of S pollen was formed on each anther stages except anther stage I in vitro. Callus formation was effective just before or just after at first pollen mitosis, while callus formation was less effective at tetrad or mature pollen staes. Low temperature pretreatment on the first pollen mitosis anthers with 1℃ or 5℃ for 10 days induced above 25% of S pollen. Embryogenic S pollen were divided mostly into A type at 10℃ for 10 days pretreatment and rate of B type pollen was appeared 4.3% which was 5 times more than control. Callus formation was effective at 10℃ for 10 days pretreatment.

공업계 고등학교 건축 관련 전문 교과목에 제시된 진로 교육 내용 분석

최병정,이영석 경기대학교 2005 論文集 Vol.49 No.-

This study analyzed the contents of career education that were presented in 5 professional textbooks related to the construction(Construction Structure , Architectural Design, Construction Technology I, Construction Technology II, and Construction Technology III) for Technical High School. The purpose of this study is to analyze whether the contents of career education within 5 professional textbooks that are learned by students majoring in architecture at the Technical High School, are presented in line with the principle of continuity. The contents were from the professional textbooks among the fields for the contents of career education, and to what extent those are shown. Given synthesizing the analyzed results, first, in 5 professional textbooks that are learned by students majoring in architectural department at Technical High School, the contents in career education are forming disproportion among spheres. Second, in 4 textbooks(Construction Structure, Architectural Design, Construction Technology I. and Construction Technology II) among 5 professional textbooks analyzed, the principle of continuity was not rightly kept. Given putting forward the improvement plans based on these, first, among contents in career education for 5 analyzed textbooks, it is required to allow the spheres for 'human relationship' and 'understanding of economic aspects of work' to possibly appear, and to allow the field for 'self-understanding' to be supplemented a little more. Second, in 「Construction Structure」, 「Architectural Design」, 「Construction Technology I」, and 「Construction Technology II」, the contents in career education need to be formed in line with the principle of continuity Third, it is required the general adjustment in contents between spheres and between each of textbooks for career education, by analyzing the contents in career education that were shown in all the professional textbooks and ordinary textbooks that are learnt by students majoring in architectural department at Technical High School. Finally, it is required to make the detailed guidelines for the contents in career education by textbook in line with the principle of career education on the basis of objectives and contents in career education for a high school.

물류시스템에서의 수요형태에 따른 로트크기 결정기법의 비교분석

김병석,강경식,송수정 明知大學校 産業技術硏究所 1995 産業技術硏究所論文集 Vol.14 No.-

This study is to find the lot sizing technique based on demand pattern in the distribution system. In general, the lot sizing techniques used in the distribution system is the same as the methods of MBP system. This couldn't be applied at the distribution system because of very complicate and manager's lack of understand. The lot sizing techniques used for analyzing and emphasizing productivity in this study are compared with EOQ, LFL, POQ, LTC and PPB.

상부 위암에서 유문보존 근위부 위아전절제술과 공장간치술을 시행한 위전절제술의 비교

노승무,정현용,이병석,조준식,신경숙,송규상,이태용 충남대학교 암공동연구소 2003 암공동연구소 업적집 Vol.3 No.

Purpose: The aim of this study was to evaluate the short-term outcome of a pylorus-preserving proximal gastrectomy by comparing it with a jejunal interposition after a total gastrectomy in proximal gastric adenocarcinoma. Materials and Methods: For 22 patients (12 men and 10 women) who underwent a pylorus-preserving proximal gastrectomy, several clinical parameters were obtained from the medical records retrospectively. In this study, the data were collected between September 1993 and December 1999 at Chungnam National University Hospital, and the results were compared with those of 25 patients (17 men and 8 women) who underwent an isoperistaltic simple jejunal interposition. Results: The average operative time in the pylorus-preserving proximal gastrectomy group (220 minutes) was shorter than that in the jejunal interposition group (243 minutes) (P<0.05). The hemoglobin and hematocrit levels were significantly higher in the pylorus-preserving proximal gastrectomy group at 2 years after the operation. The body weight ratio (postoperative body weight/preoparative body weight) in patients who had a pylorus-preserving proximal gastrectomy was significantly higher than that in patients with a jejunal interposition at 2 years after the operation. The jejunal interposition procedure had better outcomes in anastomotic site stricture, duration of hospital stay, and number of removed lymph nodes (P<0.05). Conclusions: We think that from the viewpoint of quality of life, a pylorus-preserving proximal gastrectomy, as well as a jejunal interposition, is a useful reconstruction method for early adenocarcinomas of the proximal stomach. However, stricture of the esophagogastrostomy site in the pylorus-preserving proximal gastrectomy is a common problem to be solved in the future. (J korean Gastric Cancer Assoc 2002;2:145-150)