원문 : 좌업 시간과 알코올 섭취가 30대 남자 사무직 근로자의 혈압과 혈관탄성에 미치는 영향

조봉오 ( Bong Oh Cho ),이인녕 ( In Yeong Lee ),정균근 ( Gyun Geun Jeong ),장창현 ( Chang Hyun Jang ) 한국운동생리학회(구 한국운동과학회) 2014 운동과학 Vol.23 No.3

조봉오, 이인녕, 정균근, 장창현. 좌업 시간과 알코올 섭취가 30대 남자 사무직 근로자의 혈압과 혈관탄성에 미치는 영향. 운동과학, 제23권 3호, 241-248, 2014. 본 연구의 목적은 일과 중 대부분을 좌업근무 형태로 업무를 수행하고, 스트레스로 인해 음주가 잦고, 운동이 부족한 30대 남자 사무직 음주자 15명을 대상으로 좌업 시간과 알코올 섭취가 혈압과 혈관탄성에 미치는 영향을 분석하여 사무직 근로자에게 건강관리에 필요한 정보를 제공하는데 있다. S대학 운동 생리학 실험실에서 사전 인적 사항과 설문을 작성하고, 신장, 체중, 채혈, 혈압, 혈관탄성, BMI를 측정하였다. 알코올 섭취 횟수, 섭취량, 좌업 시간, 그리고 음주 섭취 전과 후 및 시간대별 (10분, 40분, 60분) 혈압과 혈관탄성의 변화를 측정 분석한 결과를 요약하면 다음과 같다. 1) 평균 좌업시간이 9.87시간, 음주횟수 및 음주량은 월 평균 9.13회와 12.47잔 이였다. 2) 알코올 섭취횟수 및 섭취량에 따른 BMI, TC, LDL-C, HDL-C, 혈압과 혈관탄성 비교에서 알코올 섭취횟수에서 좌상지 혈관탄성은 통계적으로 유의한 차이를 나타냈다(p<.05). 3) 알코올 섭취 전, 후 비교 분석 결과 우상지와 좌상지의 혈관탄성에서 통계적으로 유의한 차이가 나타났다(p<.05). 4) 알코올 섭취 후 시간대별 우상지 혈관탄성은 통계적으로 유의한 차이를 나타냈다(p<.05). 이상의 결과를 종합해 볼 때, 좌업 시간이 혈압과 혈관탄성에 미치는 영향은 통계적으로 유의하게 나타나지 않았고, 알코올 섭취는 혈관탄성에 통계적으로 유의한 차이를 나타냄을 알 수 있었다. 따라서 이는 직장생활의 스트레스를 음주로 해소하는 경향이 있음을 보여주며 건강에 부정적인 영향을 주고 있음을 알 수 있었다. 또한, 신체가 음주에 적응되어 실험 시 섭취한 적은 양(1/2병)은 1회 12.47잔에 비해 혈압과 혈관탄성에 큰 영향을 미치지 못한 것으로 사료된다. Cho, Bong-Oh, Lee, In-Yeong, Jeong, Gyun-Geun, Jang, Chang-Hyun. Effects of Sedentary Occupation Time and Alcohol Intake on Blood Pressure and Vascular Compliance in 30s Male White-Collar Workers. Exercise Science, 23(3): 241-248. 2014. The purpose of this study was to examine effects of duration of sedentary office work and alcohol intake on blood pressure and vascular compliance in male subjects who were office workers aged between 30 to 39 and frequently drink alcoholic beverages to cope with their stress without exercising for health. The study was to provide health-related information necessary for white-collar workers. We collected data of demographic information, height, weight, blood sample, blood pressure, vascular compliance, and BMI from 15 subjects in S University`s Exercise Physiology Laboratory, and analyzed the frequency and amount of alcohol intake, duration of sedentary work, and changes in blood pressure and vascular compliance at diffident time points (10, 40, and 60 minutes post drinking) from baseline. I t was found that the average time of sedentary work was 9.87 hours, drinking 9.13 times a month on average, 12.47 glasses of alcohol beverages per drink. In comparison of BMI, TC, LDL-C, HDL-C, blood pressure and vascular compliance upon the frequency and amount of alcohol intake, the upper left limb`s vascular compliance had a statistically significant difference (p<.05). In the result of the comparative analysis of pre-and post-drinking, vascular compliance was significantly different in the upper right and left limbs (p<.05). Vascular compliance in the upper right limb after drinking significantly changed (p<.05). As a result, the duration of sedentary work had no statistically significant difference in blood pressure and vascular compliance. T he vascular compliance after drinking h ad a statistically significant difference. This suggested that the result was an index that shows the trend of the office workers releasing their work stress by drinking alcoholic beverages, and that drinking had negative impacts on them. In addition, a small amount of intake (a half bottle) at the test time, after the body was adjusted to drinking, compared with 12.47 glasses per intake, had no great impacts on blood pressure and vascular compliance.

초등학교에서의 시설배치유형에 따른 공유영역에 관한 연구 : 광주광역시 초등학교를 중심으로 Focusing on Elementary School in Kwangju

오지영,이봉수,조용준 朝鮮大學校 建設技術硏究所 1999 建設技術硏究 Vol.19 No.3

The common territory of human activity within elementary school is the intermediate area transferred into the private internal area from public external area, accommodates the various acts and is the area of social exchange to settle the extinction from others and to keep a good relationship with them. Common Territory can be divided into the central area which is the first stage in the process of making public area with strong sense of ownership and exclusiveness according to cultural and social environmental characteristics, association area as the place of intermediary nature between public facilities and places which can enhance the sense of closeness by its users and exchange area which can give users the sense of symbolic belonging as the public space by optional and active exchanges by a special motif rather than by direct contact. This study divides the types of common territory used by students and summarizes its users as follows. From the students' side, the common territory used by them is the intermediary area of public areas like playground and gymnasium and the most private area like classroom and it has the types of entrance, arcade connecting central hall and other school buildings, stairs for moving to other classrooms. The frequency of their uses are different depending in the time of use, that is, break, lunch time or after school, but the corridor is most frequently used by students, followed by stairs, entrance, central hall and arcade. It is used mainly for talks or simple play and the sense of public ownership like affection, sense of belonging and exclusiveness and characte-risitcs of close association are shown.

농촌지역 초등학교 유휴시설의 활용방안에 관한 연구 : 해남군 초등학교를 중심으로 Focused on the Elementary School in Hae-Nam

오재섭,이봉수,박향용,유창균,조용준 朝鮮大學校 建設技術硏究所 1998 建設技術硏究 Vol.18 No.2

Recently, number of elementary school students in the rural area have decreased due to move of population to the diminishment of birth population, the generation of idle facilities and even the trend of abolition of school presented problems. This paper was a study of the use plans and generation pattern of idle facilities in present school. And the targeted schools of this study were elementary schools located at Hae-Nam Province in Chun-Nam. The results are as follows : 1) While the number of the elementary school is continuosuly decreased up to now since 1980, the number of branch schools and closed schools is increasing and while general class is decreased continuously, multiple classes are increasing and so the utilization of idle facilities will be continued. 2) The utilization of idle facilities is most frequent in the use of school curriculm(67%), followed by the use of club activities and welfare facilities, but the use by residents is minimum. In the problems in using idle facilities, the lack of finance is most(68%), followed by the lack of illustrative data and technical problems and in the effects of using idle facilities, extra curriculum activities are best and followed by the use of local community and school curriculum. 3) In the most required facilities in using idle facilities, gymnasium and service area are highest and followed by laboratory, learning data room and library and in the common facilities with local residents, swimming pool is most frequent and followed by library.

마우스에서 회양목 추출물의 단회투여독성시험

오정민,조재훈,김봉희,김상겸 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

The single dose toxicity of Buxus microphylla var. koreana Nakai was evaluated in ICR mice. Twenty five mice of each sex were randomly assigned to five groups of 5 mice each and were administered singly by gavage at dose of 0, 222, 667, 2,000 and 5,000 mg/kg body weight. After single administration, signs of toxicity were observed every hour for the first 6 hours and every day for 14 days. At the end of 14-day observation period, all animals were sacrificed for gross postmortem examinations. Neither significant toxic signs nor death was observed during the observation period. In addition, no pathological changes were noticed in macroscopic examination at necropsy. These results indicate that the single oral administration of Buxus microphylla var. koreana Nakai did not cause any toxic effect at the dose of 5,000 mg/kg body weight for both sexes and LD_(50) of Buxus microphylla var. koreana Nakai is greater than 5,000 mg/kg body weight.

시간가변계수를 이용한 Feldstein-Horioka 저축보유계수 추정

오근엽,김봉한,김홍기 충남대학교 경상대학부설 경영경제연구소 1997 경영논집 Vol.13 No.1

본고에서는 시간가변계수모형을 이용하여, Taylor의 자료를 가지고 FH의 저축보유계수를 추정하였다. 이에 이용된 계량기법은 Kalman Filter와 TVC 공적분 방법이다. 그 결과 우리는 양자의 결과가 크게 다르지 않음을 보았다. 또한 우리의 결과는 기존의 논문중의 대표적인 것중의 하나라고 보여지는 Taylor의 결과에도 크게 다르지 않았다. 다만 본 논문에서는 FH저축보유계수의 시간별 변화를 Taylor에 비해서 훨씬 자세하게 볼 수 있게 되었다는 점에서 그 의의가 있다.

뇌성마비 아동의 임상특성과 관리

오상근,이동배,김봉옥,임종훈 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2

To understand clinical characteristics of children with cerebral palsy, ninety three children who were diagnosed to have cerebral palsy in the Department of Rehabilitation Medicine, Chungnam National University Hospital were studied retrospectively. Their medical records were reviewed to see the types of cerebral palsy, distribution of paralysis, possible cause of cerebral palsy, history of seizure, result of brain imaging studies, such as Computerized Tomography (CT), Magnetic Resonance Imaging (MRI), Electroencephalography (EEG), and Auditory Evoked Potential (AEP) study. The results were as follows : 1) They were sixty-four boys (68.8%) and twenty-nine girls (31.2%) with ages ranging from six months to sixteen years, three months (mean : 3 years 11 months) at initial visit and mean duration of follow up was two years, eight months. 2) The most common type of cerebral palsy was spastic (82.7%) followed by mixed, athetoid, ataxic and rigidity types listed in the order of frequency. 3) Topographic distribution of spastic paralysis was led by diplegia (55.8%) followed by tetraplegia (27.3%), hemiplegia (14,3%), and monoplegia (2.6%).. 4) Prematurity and low birth weight were the leading possible causes for cerebral palsy. 5) Incidence of seizure was 23.6% among these children. 6) History of seizure was not directly correlated with abnormal findings of brain imaging, EEG, or AEP, and clinical correlation is recommended. 7) Forty-nine children (52.7 %) were under regular treatment or special education programs provided locally. Problems such as lack of treatment facilities, financial burden, insufficient treatment time, and unsatisfactory treatment, etc. were noted. With the results above, a locally available, more comprehensive management program is highly recommended to provide the children with cerebral palsy the early diagnosis, appropriate, timely intervention, regular treatment, and special education that are needed. Furthermore, ways to prevent prematurity and low birth weight infant should be sought as they are major risk factors for cerebral palsy.

Protein kinase A 억제제인 KT5720이 글루카곤 매개성 항산화 효소의 발현감소에 미치는 영향

오수진,조재훈,박창식,김상겸,김봉희 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

We reported previously that glucagon decreased alpha- and pi-class glutathione S-transferases (GSTs) and microsomal epoxide hydrolase (mEH) protein levels in primary cultured rat hepatocytes. The present study examines the effects of protein kinase A (PKA) inhibitor, KT5720, on the glucagon-mediated decrease in expression of GSTs and mEH. To assess cell viability, lactate dehydrogenase release and MTT activity were examined in hepatocytes treated KT5720. Cell viability was significantly decreased in a concentration-dependent manner after incubation with KT5720 at the concentrations of I μM or above for 24 h, which was inhibited by the cytochrome P450 inhibitor SKF-525A. In contrast, another PKA inhibitor H89 (up to 25μM) was not toxic to hepatocytes. The glucagon-mediated decrease in expression of alpha- and pi-class GSTs and mEH was completely inhibited by 25μM H89 and attenuated by O.1μM KT5720. This study demonstrates that KT5720 may cause cytotoxicity in rat hepatocytes through cytochrome P450-dependent bioactivation. The present study implicates PKA in mediating the inhibitory effect of glucagon on expression of alpha- and piclass GSTs and mEH.

a-Si:H/a-SiN:H 초격자의 제작 및 특성조사

오성수,양승훈,박봉두 경북대학교 산업기술연구소 1987 産業技術硏究誌 Vol.15 No.-

We fabricated a-Si : H/a-SiN : H superlattices using the RF glow discharge system which was equipped with sliding mask and liquifing system of exhausting gases. Samples were deposited at substrate temperature of 250℃, deposition rate of 0.8 - 1.0 A˚/sec, deposition pressure of 200 mTorr (SiH_4) and 400 mTorr (SiH_4 + NH_3), and Rf power density of 150-200 mW/㎠. Employing a-Si: H layer thickness as a deposition parameter (fixing a-SiN : H layer at 30A˚), we found that the decrease of a-Si : H layer thickness (600→60A˚) was accompanied with the increase of activation energy (0.8→1.0eV). And in particular, persistent photoconductivity was clearly observed in the samples with 60A˚ a-Si :H.

Cu^2+-quinolone 복합체 존재하 DNA의 DNase Ⅰ에 대한 가수분해 반응성 증가

吳鳳京,徐正仁,柳聲元,高東成 충남대학교부설 생명공학연구소 1991 생물공학연구지 Vol.1 No.-

특히, 그람음성 세균에 대한 활성을 가지며 Escherichia coli, Proteus 및 Klebsiella류의 감염에 의한 요도염(urinary tract infections)의 임상학적 치료에 유효함이 증명된1-5 합성 항균제인 nalidixic acid(lethy1-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid)를 비롯한 quinolones 항균제의 개발연구가6 국내외 공히 활발하게 진해되고 있음에도 불구하고 그 작용 메커니즘이 제대로 밝혀지지 못하고있는 실정이다. 이들은 DNA합성을 방해 하므로써 향균 기능을 갖는다고 알려져 있으나 그 표적물(target)이 무엇인가에 대하여는 불분명하다. 이들 quinolones는 생리적 pH에서 음이온으로 존재하므로 정전기적 반발로 인하여 다음이온성(polyanionic)인 DNA와의 직접적 상호작용 가능성이 배제되어 왔으며 일반적인 견해는 DNA gyrase subunit A가 nalidixic acid의 특이한 target인 것으로 알려져 있다.

한국의 국제수지 불균형과 외환시장 압력

吳根燁,黃京淵,成奉錫 충남대학교 경상대학부설 경영경제연구소 1996 경영논집 Vol.11 No.2