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함준수(Joon Soo Hahm),이동후(Dong Hoo Lee),박경남(Kyung Nam Park),이민호(Min Ho Lee),이종철(Jong Chul Rhee),기춘석(Choon Suck Kee),유대현(Dae Hyun Yoo) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.2
N/A Gastric emptying time(GET) is influenced by several factors, such as neura), hormonal and composi- tion and physiochemical properties of food. The patients with delayed GET have some upper gastrointestinal symptoms such as recurrent nausea, vomiting, postprandia! Bloating, anorexia, and iveight loss. And also, almost of acute hepatitis and a part of chronic ]iver disease patients have similar symptoms of the patients with delayed GET. Therefore We performed GET measurement in liver disease patients to identify the relationship between nonspecific upper gastrointestinal symp- toms and gastric emptying function. The resu]ts are as followings; 1) Total ]iver disease patients are 28 in number, composed of acute hepatitis 3, chronic hepatitis 18, liver cirrhosis 7. 2) The GET(T1/2) of liver disease patients was delayed significantly than that of the normal volunteers. (Mean+SE;120.8+6.6 vs 89.4+5.9 mins.) 3) The GET of the symptomatic patients (N = 20 ) ivas 128.3+6.8 mins (Mean+SE), and that of the asymptomatic patients (N =8) was 101.8+13.2 mins. The symptomatic patients have delayed GET in 10 patients and asymptomatic patients have delayed GET in 3. 4) The GET of the patients who have elevated serum transaminase level higher than twice of normal is delayed significantly than that of the patients who have serum transaminase level lower than twice of normal. (Mean+SE; 143.4+2.6 vs 110.0+7.4 mins.)
거래비용이 상이한 복수의 유통채널에 대한 다자간 협상전략에 관한 연구
조형래(Hyung Rae Cho),이민호(Min ho Rhee) 한국산업경영시스템학회 2015 한국산업경영시스템학회지 Vol.38 No.4
The proliferation of the Internet and communication technologies and applications, besides the conventional retailers, has led to a new form of distribution channel, namely home sopping through the telephone, TV, catalog or the Internet. The conventional and new distribution channels have different transaction costs perceived by the consumers in the following perspectives: the accessibility to the product information, the traffic cost and the opportunity cost for the time to visit the store, the possibility of 'touch and feel' to test the quality of the product, the delivery time and the concern for the security for the personal information. Difference in the transaction costs between the distribution channels results in the different selling prices even for the same product. Moreover, distribution channels with different selling prices necessarily result in different business surpluses. In this paper, we study the multilateral bargaining strategy of a manufacturer who sells a product through multiple distribution channels with different transaction costs. We first derive the Nash equilibrium solutions for both simultaneous and sequential bargaining games. The numerical analyses for the Nash equilibrium solutions show that the optimal bargaining strategy of the manufacturer heavily depends not only on the degree of competition between the distribution channels but on the difference of the business surpluses of the distribution channels. First, it is shown that there can be four types of locally optimal bargaining strategies if we assume the market powers of the manufacturer over the distribution channels can be different. It is also shown that, among the four local optimal bargaining strategies, simultaneous bargaining with the distribution channels is the most preferred bargaining strategy for the manufacturer.
제조업체, 온라인 유통채널 및 오프라인 유통채널 간의 다자간 협상전략에 관한 연구
조형래(Hyung Rae Cho),이민호(Min ho Rhee),임상규(Sang Gyu Lim) 한국산업경영시스템학회 2014 한국산업경영시스템학회지 Vol.37 No.4
In this paper, we study the bargaining strategy of a manufacturer who sells a product through the online and offline distribution channels. To do this, we derive and analyze the equilibrium solutions for both simultaneous and sequential bargaining games. The result shows that the optimal bargaining strategy heavily depends on the size of the online distribution channel's loyal customers and the difference between the retail prices of the online and the offline distribution channels. It is also shown that, in some cases, the online distribution channel has incentive to downsize its loyal customers and its retail price for a better bargaining outcome.
만성 간질환에서의 ICG - Rmax 와 Thallium - 201 Test per Rectum ( Sunt Index ) 의 임상적 의의
이경상(Kyung Sang Lee),황선호(Seon Ho Hwang),함준수(Joon Soo Hahm),이종철(Jong Chul Rhee),기춘석(Choon Suhk Kee),박경남(Kyung Nam Park),이민호(Min Ho Lee),정화순(Wha Soon Chung),조석신(Seok Shin Cho),이재원(Jae Won Lee) 대한내과학회 1994 대한내과학회지 Vol.46 No.1
N/A Objectives: Thallium-201 test per rectum (shunt index) and ICG-Rmax have been used for studying the portosystemic shunt and the functional reserve of liver. The clinical values of shunt index and ICG-Rmax in pateints with chronic liver disease were evaluated using the data obtained in 74patients. Methods: 0.5mCi thallium-201 was administered per rectum to 37 patients witchronic active hepatitis (CAH) and 37Patients with liver cirrhosis, and the heart to liver uptake ratio was taken at 20min. ICG-Rmax was also taken using Paumgartner`s method. We used simple linear regression and ANOVA methods for the correlation between ICG Rmax and shunt index. Results: 1) The mean shunt index was 0.251±0. 140 in CAH group and 0.565±0.351 in cirrhosis group (P<0,005). 2) The mean ICG-Rmax was 1.720±l.320 (mg/kg/ min) in CAH group and 0.867±0.625 in cirrhosis group (P<0 005). 3) There was no significant correlation between ICG- Rmax and shunt index in CAH group (P=0.358). 4) Correlation between ICG-Rmax and shunt index was significant in cirrhosis group (P=0,001; R-square= 0 321; 1/ICG-Rmax=2 64 * shunt index+0.49) Conclusions: Thallium-201 scintigraphy per rectum and ICG-Rmax may be useful in diagnosis of chronic liver diseases, especially differentiating CAH from cirrhosis. These study will help us to predict the prognosis of chronic liver diseases and give us more information for the treatment of chronic liver diseases.
간장 및 담도 : 간세포암 치료에 있어서 간동맥 색전술의 이용 - 임상경험 24예 -
기춘석(Choon Suhk Kee),박경남(Kyung Nam Park),이민호(Min Ho Lee),이성구(Sung Koo Lee),이종철(Jong Chul Rhee),유종상(Jong Sang Ryue),최호순(Ho Soon Choi),박민선(Min Sun Park),서흥석(Heung Suk Seo) 대한소화기학회 1986 대한소화기학회지 Vol.18 No.1
N/A 24 patients with unresectable hepatocellular carcinoma were treated with transcatheter arterial embolization. The results were as followings: 1) The serum levels of AFP were decreased in about 80 percent of the patients with elevated AFP. 2) We found the low density areas in the CT after embolization which meant the effect. 3) Side effects were fever, nausea and vomiting in almost of all patients but subsided within several to ten days.
간장및 담도 : 만성간질환 환자의 상부위장관 증상에 대한 Domperidone 효과에 대한 연구
함준수(Joon Soo Hahm),이동후(Dong Hoo Lee),이민호(Min Ho Lee),이종철(Jong Chul Rhee),기춘석(Choon Suck Kee),이오영(Oh Yong Lee),안종훈(Jong Hoon Ahn),박경남(Kung Nam Park),조석신(Suck Shin Cho) 대한소화기학회 1990 대한소화기학회지 Vol.22 No.2
N/A The fact that chronic hepatitis patients with dysfunctional upper gastro-intestinal symptoms have delayed gastric empting time was documented in our previous study. Fifteen patients with chronic hepatitis participated in a assessment of the effects of domperidone on gastric empting time and dysfunctional upper gastrointestinal symptoms such as recurrent nausea, vomiting, postprandial bloating, anorexia and meight loss. They were each given domperidone 10 mg t.i.d. for four weeks. The resu1ts are as folIowing; 1) The total patints with chronic hepatitis are 15 in number, composed of chronic active hepatitis 9, chronic persistant hepatitis 6. 2) The GET (T 1/2) OF 15 patients with chronic hepatitis was delayed significantly than that of the normal control. (Mean +- SE; 135.0 +- 6.0 vs 89.4 +- 5.9 mins) (p<0.05). 3) Follow-up GET (T 1/2) of these patients after domperidone treatment were 116.0 +- 5.5 mins but those results were not statistically significant different from initial GET (T 1/2) (135.0 +- 6.0 mins). 4) Domperidone significantly promote dysfunctional gastrointestinal symptoms such as recurrent nausea, vomiting, postprandial bloating, anorexia, and weight loss. (Mean +- SE; 4.3 +- 0.2 vs 0.8 +- 0.2 symptom scores) (p<0.05). 5) The two side effect seen only with domperidone, diarrhea and mild abdominal pain occurred in one patient each and neither was severe enough to require discontinuing the study. No neurologic problems were noted.
상부위장관 내시경검사 전처치제로 투여한 Rociverine Citrate 의 효과에 관한 관찰
함준수(Joon Soo Hahm),기춘석(Choon Suhk Kee),박경남(Kyung Nam Park),이민호(Min Ho Lee),이종철(Jong Chul Rhee),윤호주(Ho Ju Yung) 대한소화기학회 1988 대한소화기학회지 Vol.20 No.1
N/A A new synthetic smooth muscle-relaxant, Rociverine citrate (Danapen), was tested for spasmolytic action on the smooth musculature of the pyloric sphincter against Hyoscine butylbromide. The total number of subjects was 262 patients and 10 mg of Rociverine citrate were intramuscularly given in 128 cases and 20 mg of Hyoscine butylbrornide were given in the 134 cases. The drug effect were assessed on the degree of opening of the pyloric sphincter and the endoscopists rating of drug performance. The results were as follows; 1) About the pyloric sphincter status, 116 cases (90.6%) of Rociverine citrate premedicated group and 115 cases (85.8%) of Hyoscine butylbromide premedicated group and 115 cases (85.8%) of Hyoscine butylbromide premedicated group showed above than fair response. 2) The ratings of examination procedure by the endoscopist were very good in 76.6%, good in 20.3%, fair in 2.3%, and ineffective in 0.8%, in Rociverine premedicated group and very good in 73.1%, good in 22.4%, fair in 3.7%, and ineffective in 0.8%, in Hyoscine butylbromicle premedicated group. 3) No adverse effects were noted in Rociverine citrate group. Thus, we concluded that the Rociverine citrate is an active drug as a premedication drug for upper endoscopic examination.
B 형 간염바이러스와 연관된 각종 간질환군에서의 혈중 Alphal - Antitrypsin 치의 의의
고윤석(Youn Suck Koh),류우진(Woo Jin Lew),윤호주(Ho Ju Yun),함준수(Joon Soo Hahm),이종철(Jong Chul Rhee),이민호(Min Ho Lee),기춘석(Choon Suhk Kee),박경남(Kyung Nam Park) 대한내과학회 1988 대한내과학회지 Vol.35 No.1
N/A We studied the clinical significance the progress of of α1-antitrypsin (a-AT) as an indicator of hepatitis B virus related diseases, and as a marker of hepatoma by estimating the serum α1-AT level. The results are as follows: 1) The mean and standard deviation of the serum α1-AT level in each group was 198+30 mg/dl in healthy controls, 174±29mg/dl in healthy carriers, 263±68mg/ dl in acute viral hepatitis, 203±57 mg/dl in chronic viral hepatitis, 233±50mg/dl in chronic active hepatitis, 237±71mg/dl in liver cirrhosis, and 346±101mg/dl in hepatoma. 2) The α1-AT level of hepatoma showed the highest elevation in each group (p<0.05). 3) When using 330mg/dl of a-AT as the cut-off value of hepatoma, 27 of 52cases of hepatoma were included. In 20cases of hepatoma which were below 500ng/ml of alpha-Fetoprotein, 12 of the cases were above 330mg/dl of α1-AT. 4) When considering the convenience and laboratory cast of α1-AT, with the above results, we suggest that more extensive studies be done, in the areas of α1-AT as an indicator of the progress of hepatitis B virus related diseases, and as a complemental marker of hepatoma.
완충액과 담즙염 용액사이의 불포화 빌리루빈의 동질분획에 대한 연구
함준수(Joon Soo Hahm),이동후(Dong Hoo Lee),박경남(Kyung Nam Park),이민호(Min Ho Lee),이종철(Jong Chul Rhee),한동수(dong Soo Han),기춘석(Chon Suhk Kee) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.2
N/A Bilirubin is a major component of gallstones and the solubility of unconjugated bilirubin (UCB) has been shown to play an important role in gallstone formation. The mechanism of gallstone formation and solubilization of UCB is, however, still unknown. Several investigators have attempted to determine the chemical nature of bilirubin which are thought to be closely related to its solubility. Hoivever, there is some controversy over the ionization constants and pK values of carboxyl groups of UCR. In the present study, the effect of pH, the type and concentration of bile salt on UCB solubility were studied and the pK values of bilirubin were calculated. The results were as follows: 1) There are more solubilities with higher bile salt concentrations and with increasing pH, and bile salt plays an important role in solubilizing UCB in bile. 2) Bile salt monomers, dimmers and micelles are equally effective in solubilizing bilirubin. 3) The bilirubin in bile is almost entirely in the monoanion (BH- ) form at physiological pH values.